Characterization of hepatitis C virus (HCV) quasispecies dynamics upon short-term dual therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS3/4 protease inhibitor danoprevir.

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Published in Antimicrob Agents Chemother on August 06, 2012

Authors

S Le Pogam1, J M Yan, M Chhabra, M Ilnicka, H Kang, A Kosaka, S Ali, D J Chin, N S Shulman, P Smith, K Klumpp, I Nájera

Author Affiliations

1: Roche, Nutley, New Jersey, USA.

Associated clinical trials:

A Study of Combination Treatment With an HCV Polymerase Inhibitor (RO5024048) and an HCV Protease Inhibitor (RO5190591/Danoprevir) in Genotype 1 Chronic Hepatitis C Patients | NCT00801255

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