Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
3
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
4
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
5
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
6
|
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study.
|
Lancet
|
2012
|
8.42
|
7
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
8
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
9
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
10
|
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.
|
PLoS One
|
2007
|
4.92
|
11
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
12
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
13
|
Genome-wide association study identifies five loci associated with lung function.
|
Nat Genet
|
2009
|
4.10
|
14
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
15
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
16
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
17
|
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
|
PLoS Genet
|
2010
|
3.21
|
18
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
19
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
20
|
Novel biomarkers for pre-diabetes identified by metabolomics.
|
Mol Syst Biol
|
2012
|
2.39
|
21
|
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
|
PLoS Genet
|
2012
|
2.34
|
22
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
23
|
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.
|
Hum Mol Genet
|
2009
|
1.61
|
24
|
Underlying genetic models of inheritance in established type 2 diabetes associations.
|
Am J Epidemiol
|
2009
|
1.60
|
25
|
Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1.
|
BMC Microbiol
|
2006
|
1.41
|
26
|
Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium.
|
PLoS One
|
2012
|
1.31
|
27
|
Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits.
|
Hum Mol Genet
|
2013
|
1.23
|
28
|
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies.
|
Diabetes
|
2006
|
1.18
|
29
|
The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms.
|
Blood
|
2010
|
1.16
|
30
|
DNA methylation of lipid-related genes affects blood lipid levels.
|
Circ Cardiovasc Genet
|
2015
|
1.12
|
31
|
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.
|
Ann Med
|
2009
|
1.10
|
32
|
Childhood obesity is associated with changes in the serum metabolite profile.
|
Obes Facts
|
2012
|
1.05
|
33
|
An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes.
|
Diabetes
|
2011
|
1.02
|
34
|
Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).
|
BMC Med Genet
|
2010
|
0.96
|
35
|
BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1.
|
Diabetes
|
2010
|
0.95
|
36
|
Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years.
|
Obes Facts
|
2010
|
0.94
|
37
|
Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.
|
Am J Epidemiol
|
2013
|
0.93
|
38
|
Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations over the duration of lactation.
|
Am J Clin Nutr
|
2010
|
0.93
|
39
|
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.
|
PLoS Genet
|
2010
|
0.91
|
40
|
Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
|
PLoS One
|
2013
|
0.90
|
41
|
Multi-omic signature of body weight change: results from a population-based cohort study.
|
BMC Med
|
2015
|
0.89
|
42
|
Association of a MTNR1B gene variant with fasting glucose and HOMA-B in children and adolescents with high BMI-SDS.
|
Eur J Endocrinol
|
2010
|
0.89
|
43
|
Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans.
|
PLoS One
|
2012
|
0.89
|
44
|
Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.
|
BMC Med Genomics
|
2012
|
0.87
|
45
|
Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa.
|
Obes Facts
|
2012
|
0.87
|
46
|
Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.
|
PLoS One
|
2012
|
0.87
|
47
|
Changes in the serum metabolite profile in obese children with weight loss.
|
Eur J Nutr
|
2014
|
0.86
|
48
|
Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry.
|
BMC Med Genet
|
2009
|
0.86
|
49
|
Modulation of insulin degrading enzyme activity and liver cell proliferation.
|
Cell Cycle
|
2015
|
0.85
|
50
|
An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker.
|
Pain
|
2015
|
0.85
|
51
|
Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.
|
Circ Cardiovasc Genet
|
2012
|
0.83
|
52
|
PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort.
|
Cardiovasc Diabetol
|
2014
|
0.82
|
53
|
Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations.
|
J Clin Endocrinol Metab
|
2007
|
0.82
|
54
|
On the potential of models for location and scale for genome-wide DNA methylation data.
|
BMC Bioinformatics
|
2014
|
0.81
|
55
|
Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample.
|
Am J Epidemiol
|
2008
|
0.81
|
56
|
Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity.
|
BMC Med Genet
|
2010
|
0.80
|
57
|
Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.
|
Obes Facts
|
2009
|
0.80
|
58
|
MTTP variants and body mass index, waist circumference and serum cholesterol level: Association analyses in 7582 participants of the KORA study cohort.
|
Mol Genet Metab
|
2008
|
0.80
|
59
|
First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.
|
J Epidemiol Community Health
|
2010
|
0.80
|
60
|
SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents.
|
Obesity (Silver Spring)
|
2011
|
0.80
|
61
|
Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups.
|
BMC Med Genet
|
2009
|
0.79
|
62
|
Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity.
|
PLoS One
|
2013
|
0.78
|
63
|
Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.
|
Eur J Endocrinol
|
2010
|
0.78
|
64
|
Genome-wide association study (GWAS) for molar-incisor hypomineralization (MIH).
|
Clin Oral Investig
|
2013
|
0.78
|
65
|
Association analysis between the prostaglandin E synthase 2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort.
|
Genet Test Mol Biomarkers
|
2009
|
0.78
|
66
|
No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children.
|
J Pediatr Endocrinol Metab
|
2013
|
0.78
|
67
|
No association between the ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German population.
|
Psychiatr Genet
|
2015
|
0.78
|
68
|
Acute-phase serum amyloid A protein and its implication in the development of type 2 diabetes in the KORA S4/F4 study.
|
Diabetes Care
|
2012
|
0.78
|
69
|
Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.
|
Thromb Haemost
|
2009
|
0.76
|
70
|
SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis.
|
J Clin Periodontol
|
2014
|
0.76
|
71
|
Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness.
|
Horm Res Paediatr
|
2012
|
0.76
|
72
|
Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations.
|
Mol Nutr Food Res
|
2007
|
0.76
|
73
|
Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients.
|
Am J Hematol
|
2014
|
0.76
|
74
|
Occurrence of the JAK2 V617F mutation in patients with peripheral arterial disease.
|
Am J Hematol
|
2014
|
0.75
|
75
|
Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals.
|
Mol Genet Metab
|
2009
|
0.75
|
76
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
77
|
Gene variants of monocyte chemoattractant protein 1 and components of metabolic syndrome in KORA S4, Augsburg.
|
Eur J Endocrinol
|
2007
|
0.75
|
78
|
Epigenetic regulation of glucose metabolism.
|
Curr Opin Clin Nutr Metab Care
|
2017
|
0.75
|
79
|
Harmonization of study and reference data by PhaseLift: saving time when imputing study data.
|
Genet Epidemiol
|
2014
|
0.75
|
80
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|
81
|
Association between functional FABP2 promoter haplotypes and body mass index: analyses of 8072 participants of the KORA cohort study.
|
Mol Nutr Food Res
|
2009
|
0.75
|
82
|
Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome.
|
Nat Commun
|
2017
|
0.75
|