Harald Grallert

Author PubWeight™ 231.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008 35.06
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
4 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010 16.96
5 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet 2012 11.09
6 Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet 2012 8.42
7 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010 7.94
8 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet 2010 6.66
9 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
10 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One 2007 4.92
11 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
12 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet 2014 4.13
13 Genome-wide association study identifies five loci associated with lung function. Nat Genet 2009 4.10
14 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes 2010 4.07
15 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
16 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
17 Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet 2010 3.21
18 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
19 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
20 Novel biomarkers for pre-diabetes identified by metabolomics. Mol Syst Biol 2012 2.39
21 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet 2012 2.34
22 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
23 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
24 Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol 2009 1.60
25 Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1. BMC Microbiol 2006 1.41
26 Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS One 2012 1.31
27 Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits. Hum Mol Genet 2013 1.23
28 IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies. Diabetes 2006 1.18
29 The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms. Blood 2010 1.16
30 DNA methylation of lipid-related genes affects blood lipid levels. Circ Cardiovasc Genet 2015 1.12
31 Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index. Ann Med 2009 1.10
32 Childhood obesity is associated with changes in the serum metabolite profile. Obes Facts 2012 1.05
33 An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes. Diabetes 2011 1.02
34 Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS). BMC Med Genet 2010 0.96
35 BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1. Diabetes 2010 0.95
36 Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years. Obes Facts 2010 0.94
37 Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol 2013 0.93
38 Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations over the duration of lactation. Am J Clin Nutr 2010 0.93
39 Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. PLoS Genet 2010 0.91
40 Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146. PLoS One 2013 0.90
41 Multi-omic signature of body weight change: results from a population-based cohort study. BMC Med 2015 0.89
42 Association of a MTNR1B gene variant with fasting glucose and HOMA-B in children and adolescents with high BMI-SDS. Eur J Endocrinol 2010 0.89
43 Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans. PLoS One 2012 0.89
44 Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants. BMC Med Genomics 2012 0.87
45 Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa. Obes Facts 2012 0.87
46 Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes. PLoS One 2012 0.87
47 Changes in the serum metabolite profile in obese children with weight loss. Eur J Nutr 2014 0.86
48 Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry. BMC Med Genet 2009 0.86
49 Modulation of insulin degrading enzyme activity and liver cell proliferation. Cell Cycle 2015 0.85
50 An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker. Pain 2015 0.85
51 Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy. Circ Cardiovasc Genet 2012 0.83
52 PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort. Cardiovasc Diabetol 2014 0.82
53 Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. J Clin Endocrinol Metab 2007 0.82
54 On the potential of models for location and scale for genome-wide DNA methylation data. BMC Bioinformatics 2014 0.81
55 Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample. Am J Epidemiol 2008 0.81
56 Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity. BMC Med Genet 2010 0.80
57 Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome. Obes Facts 2009 0.80
58 MTTP variants and body mass index, waist circumference and serum cholesterol level: Association analyses in 7582 participants of the KORA study cohort. Mol Genet Metab 2008 0.80
59 First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study. J Epidemiol Community Health 2010 0.80
60 SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents. Obesity (Silver Spring) 2011 0.80
61 Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups. BMC Med Genet 2009 0.79
62 Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity. PLoS One 2013 0.78
63 Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin. Eur J Endocrinol 2010 0.78
64 Genome-wide association study (GWAS) for molar-incisor hypomineralization (MIH). Clin Oral Investig 2013 0.78
65 Association analysis between the prostaglandin E synthase 2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort. Genet Test Mol Biomarkers 2009 0.78
66 No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children. J Pediatr Endocrinol Metab 2013 0.78
67 No association between the ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German population. Psychiatr Genet 2015 0.78
68 Acute-phase serum amyloid A protein and its implication in the development of type 2 diabetes in the KORA S4/F4 study. Diabetes Care 2012 0.78
69 Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study. Thromb Haemost 2009 0.76
70 SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis. J Clin Periodontol 2014 0.76
71 Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness. Horm Res Paediatr 2012 0.76
72 Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations. Mol Nutr Food Res 2007 0.76
73 Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients. Am J Hematol 2014 0.76
74 Occurrence of the JAK2 V617F mutation in patients with peripheral arterial disease. Am J Hematol 2014 0.75
75 Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals. Mol Genet Metab 2009 0.75
76 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
77 Gene variants of monocyte chemoattractant protein 1 and components of metabolic syndrome in KORA S4, Augsburg. Eur J Endocrinol 2007 0.75
78 Epigenetic regulation of glucose metabolism. Curr Opin Clin Nutr Metab Care 2017 0.75
79 Harmonization of study and reference data by PhaseLift: saving time when imputing study data. Genet Epidemiol 2014 0.75
80 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
81 Association between functional FABP2 promoter haplotypes and body mass index: analyses of 8072 participants of the KORA cohort study. Mol Nutr Food Res 2009 0.75
82 Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome. Nat Commun 2017 0.75