Published in Diabetes on August 24, 2012
Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity. Front Endocrinol (Lausanne) (2013) 1.06
Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun (2014) 1.02
A novel method for identifying nonlinear gene-environment interactions in case-control association studies. Hum Genet (2013) 1.00
Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups. PLoS One (2013) 0.91
Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism. Nucl Receptor Res (2015) 0.90
Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance. Diabetologia (2013) 0.89
The contribution of biogeographical ancestry and socioeconomic status to racial/ethnic disparities in type 2 diabetes mellitus: results from the Boston Area Community Health Survey. Ann Epidemiol (2014) 0.89
Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation. Nucleic Acids Res (2013) 0.86
No detectable association of IGF2BP2 and SLC30A8 genes with type 2 diabetes in the population of Hyderabad, India. Meta Gene (2013) 0.86
Hypospadias and genes related to genital tubercle and early urethral development. J Urol (2013) 0.85
Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism. Andrology (2013) 0.85
Quantitative assessment of the effect of KCNJ11 gene polymorphism on the risk of type 2 diabetes. PLoS One (2014) 0.84
Circadian gene variants in cancer. Ann Med (2014) 0.81
Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest. Hum Hered (2014) 0.81
KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus. J Diabetes Res (2015) 0.80
Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk. Birth Defects Res A Clin Mol Teratol (2016) 0.80
The Relationship between Native American Ancestry, Body Mass Index and Diabetes Risk among Mexican-Americans. PLoS One (2015) 0.77
Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women. AIDS (2014) 0.77
Role of Ink4a/Arf locus in beta cell mass expansion under physiological and pathological conditions. J Diabetes Res (2014) 0.77
Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis. Med Sci Monit (2015) 0.77
Gene Polymorphism Association with Type 2 Diabetes and Related Gene-Gene and Gene-Environment Interactions in a Uyghur Population. Med Sci Monit (2016) 0.76
Islet biology, the CDKN2A/B locus and type 2 diabetes risk. Diabetologia (2016) 0.76
Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population. Diabetol Metab Syndr (2015) 0.75
Genetic variants in KCNJ11, TCF7L2 and HNF4A are associated with type 2 diabetes, BMI and dyslipidemia in families of Northeastern Mexico: A pilot study. Exp Ther Med (2016) 0.75
País de gordos/país de muertos: Obesity, death and nation in biomedical and forensic genetics in Mexico. Soc Stud Sci (2015) 0.75
Maternal BMI as a predictor of methylation of obesity-related genes in saliva samples from preschool-age Hispanic children at-risk for obesity. BMC Genomics (2017) 0.75
CDC123/CAMK1D gene rs12779790 polymorphism and rs10811661 polymorphism upstream of the CDKN2A/2B gene in women with gestational diabetes. J Perinatol (2017) 0.75
Can data science inform environmental justice and community risk screening for type 2 diabetes? PLoS One (2015) 0.75
The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican-Mestizo Population. Biomed Res Int (2015) 0.75
FTO Genotype and Type 2 Diabetes Mellitus: Spatial Analysis and Meta-Analysis of 62 Case-Control Studies from Different Regions. Genes (Basel) (2017) 0.75
Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children. Sci Rep (2016) 0.75
Contribution of independent and pleiotropic genetic effects in the metabolic syndrome in a hypertensive rat. PLoS One (2017) 0.75
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem (1972) 95.79
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics (2003) 53.11
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science (2007) 32.97
Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract (2009) 25.83
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet (2008) 9.39
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet (2008) 8.63
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med (2006) 7.75
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest (2007) 5.02
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes (2006) 3.79
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Diabetes (2007) 3.24
The genetics of type 2 diabetes: what have we learned from GWAS? Ann N Y Acad Sci (2010) 3.09
Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes (2007) 2.91
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function. Diabetes (2007) 2.73
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes (2006) 2.58
Prevalence and distribution of type 2 diabetes mellitus in Mexican adult population: a probabilistic survey. Salud Publica Mex (2010) 1.83
The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies. BMC Med Genet (2008) 1.68
The FTO gene is associated with adulthood obesity in the Mexican population. Obesity (Silver Spring) (2008) 1.62
Genome-wide association study of type 2 diabetes in a sample from Mexico City and a meta-analysis of a Mexican-American sample from Starr County, Texas. Diabetologia (2011) 1.60
Genetics of type 2 diabetes: the GWAS era and future perspectives [Review]. Endocr J (2011) 1.56
A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population. Diabetologia (2007) 1.50
The new type 2 diabetes gene TCF7L2. Curr Opin Clin Nutr Metab Care (2007) 1.41
The emerging genetics of type 2 diabetes. Trends Mol Med (2010) 1.38
Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes (2008) 1.33
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. J Clin Endocrinol Metab (2008) 1.31
Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies. J Am Coll Cardiol (2011) 1.26
Association of the ATP-binding cassette transporter A1 R230C variant with early-onset type 2 diabetes in a Mexican population. Diabetes (2007) 1.16
The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans. J Clin Invest (2011) 1.12
Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City. Diabetes Metab Res Rev (2010) 1.07
Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals. Diabetologia (2009) 1.02
Prevalence and characteristics of early-onset type 2 diabetes in Mexico. Am J Med (2002) 0.99
Association of TCF7L2 polymorphisms with type 2 diabetes in Mexico City. Clin Genet (2007) 0.94
Early-onset type 2 diabetes in a Mexican survey: results from the National Health and Nutrition Survey 2006. Salud Publica Mex (2010) 0.86
Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab (2004) 0.85
Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians. Diabetes (2007) 0.83
LOC387761 polymorphism is associated with type 2 diabetes in the Mexican population. Genet Test Mol Biomarkers (2011) 0.82
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Reconstructing Native American population history. Nature (2012) 3.49
Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30
Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol (2005) 3.03
Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet (2007) 2.72
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature (2013) 2.57
SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome. Circulation (2007) 2.42
PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36
Genetic ancestry is associated with subclinical cardiovascular disease in African-Americans and Hispanics from the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet (2009) 2.31
Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev (2008) 2.29
Slower fibrosis progression in HIV/HCV-coinfected patients with successful HIV suppression using antiretroviral therapy. J Hepatol (2005) 2.27
Antioxidant supplementation and lung functions among children with asthma exposed to high levels of air pollutants. Am J Respir Crit Care Med (2002) 2.22
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19
ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med (2008) 2.18
Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet (2008) 1.89
Ancestry-related assortative mating in Latino populations. Genome Biol (2009) 1.79
Chronic hepatitis C in patients with persistently normal alanine transaminase levels. Clin Gastroenterol Hepatol (2006) 1.77
High adiponectin concentrations are associated with the metabolically healthy obese phenotype. J Clin Endocrinol Metab (2008) 1.76
Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet (2012) 1.75
The FTO gene is associated with adulthood obesity in the Mexican population. Obesity (Silver Spring) (2008) 1.62
A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans. Hum Mol Genet (2010) 1.60
Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res (2008) 1.58
Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthma. J Asthma (2007) 1.57
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
Differences in allergic sensitization by self-reported race and genetic ancestry. J Allergy Clin Immunol (2008) 1.47
ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med (2003) 1.47
Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arterioscler Thromb Vasc Biol (2005) 1.46
Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics. Hum Genet (2006) 1.43
Diacylglycerol kinase K variants impact hypospadias in a California study population. J Urol (2012) 1.43
Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area. Cancer Epidemiol Biomarkers Prev (2006) 1.30
The ATP-binding cassette transporter A1 R230C variant affects HDL cholesterol levels and BMI in the Mexican population: association with obesity and obesity-related comorbidities. Diabetes (2007) 1.29
Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet (2005) 1.27
Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. J Med Genet (2013) 1.26
Metabolic syndrome and non-alcoholic fatty liver disease. Ann Hepatol (2009) 1.24
Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility. Am J Hum Genet (2003) 1.24
Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma. Pharmacogenet Genomics (2009) 1.24
Founder effect for the Ala431Glu mutation of the presenilin 1 gene causing early-onset Alzheimer's disease in Mexican families. Neurogenetics (2006) 1.24
Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients. Ann Allergy Asthma Immunol (2008) 1.23
Differences in albuminuria between Hispanics and whites: an evaluation by genetic ancestry and country of origin: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet (2010) 1.23
Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. Stroke (2005) 1.21
Association of the ATP-binding cassette transporter A1 R230C variant with early-onset type 2 diabetes in a Mexican population. Diabetes (2007) 1.16
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity. Hum Mol Genet (2008) 1.15
Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome. Diabetes (2006) 1.15
Effect of the diagnostic criteria of the International Association of Diabetes and Pregnancy Study Groups on the prevalence of gestational diabetes mellitus in urban Mexican women: a cross-sectional study. Endocr Pract (2012) 1.14
The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans. J Clin Invest (2011) 1.12
Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma. Am J Respir Crit Care Med (2007) 1.10
Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. J Biol Chem (2009) 1.08
The ABCA1 gene R230C variant is associated with decreased risk of premature coronary artery disease: the genetics of atherosclerotic disease (GEA) study. PLoS One (2012) 1.08
Relationship between recent short-acting beta-agonist use and subsequent asthma exacerbations. Ann Allergy Asthma Immunol (2008) 1.04
Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus. Arthritis Rheum (2010) 1.04
Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma. J Allergy Clin Immunol (2007) 1.02
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circ Cardiovasc Genet (2009) 1.01
Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum (2012) 1.01
The epidemiologic burden of hepatitis C virus infection in Latin America . Ann Hepatol (2012) 1.00
Genetic heterogeneity of autosomal dominant hypercholesterolemia in Mexico. Arch Med Res (2006) 0.99
Contribution of common genetic variants to obesity and obesity-related traits in mexican children and adults. PLoS One (2013) 0.96
Elevated vasoinhibins may contribute to endothelial cell dysfunction and low birth weight in preeclampsia. Lab Invest (2007) 0.95
Radioiodine treatment in autoimmune hyperthyroidism: analysis of outcomes in relation to dosage. Arch Med Res (2007) 0.94
Breast-feeding practices in Mexico: results from the Second National Nutrition Survey 1999. Salud Publica Mex (2003) 0.94
The risk of gestational diabetes mellitus among Mexican women with a history of infertility and polycystic ovary syndrome. Fertil Steril (2012) 0.91
Evolutionary responses to a constructed niche: ancient Mesoamericans as a model of gene-culture coevolution. PLoS One (2012) 0.91
A dietary pattern including nopal, chia seed, soy protein, and oat reduces serum triglycerides and glucose intolerance in patients with metabolic syndrome. J Nutr (2011) 0.91
Methylenetetrahydrofolate reductase C677T and glutathione S-transferase P1 A313G are associated with a reduced risk of preeclampsia in Maya-Mestizo women. Hypertens Res (2008) 0.90
Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes. BMC Med Genomics (2012) 0.90
Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arterioscler Thromb Vasc Biol (2009) 0.90
Balapiravir plus peginterferon alfa-2a (40KD)/ribavirin in a randomized trial of hepatitis C genotype 1 patients. Ann Hepatol (2011) 0.90
PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population. PLoS One (2012) 0.89
Population stratification in a case-control study of brain arteriovenous malformation in Latinos. Neuroepidemiology (2008) 0.89
Rheumatoid arthritis in Latin Americans enriched for Amerindian ancestry is associated with loci in chromosomes 1, 12, and 13, and the HLA class II region. Arthritis Rheum (2013) 0.89
Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia. Circ Res (2003) 0.88
Impact of traffic flow on the asthma prevalence among school children in Lima, Peru. J Asthma (2007) 0.88
Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler Thromb Vasc Biol (2008) 0.88
Poor compliance with appropriate feeding practices in children under 2 y in Mexico. J Nutr (2006) 0.85
Hypospadias and genes related to genital tubercle and early urethral development. J Urol (2013) 0.85
Hypoalphalipoproteinemia in populations of Native American ancestry: an opportunity to assess the interaction of genes and the environment. Curr Opin Lipidol (2009) 0.85
Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab (2004) 0.85
Mutations in MODY genes are not common cause of early-onset type 2 diabetes in Mexican families. JOP (2005) 0.85
[Gene geography of Chile: regional distribution of American, European and African genetic contributions]. Rev Med Chil (2014) 0.84
Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles. Arterioscler Thromb Vasc Biol (2011) 0.84
Von Hippel-Lindau disease germline mutations in Mexican patients with cerebellar hemangioblastoma. J Neurosurg (2006) 0.83
LOC387761 polymorphism is associated with type 2 diabetes in the Mexican population. Genet Test Mol Biomarkers (2011) 0.82
Association between rs2981582 polymorphism in the FGFR2 gene and the risk of breast cancer in Mexican women. Arch Med Res (2013) 0.82
Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolism. Genes Nutr (2014) 0.82
GENEHUNTER versus SimWalk2 in the context of an extended kindred and a qualitative trait locus. Genetica (2005) 0.82
Carbohydrate intake modulates the effect of the ABCA1-R230C variant on HDL cholesterol concentrations in premenopausal women. J Nutr (2011) 0.82
Delta-sarcoglycan gene polymorphism frequency in Amerindian and Mestizo populations of Mexico. Genet Test Mol Biomarkers (2010) 0.81