Wolfgang Hans

Author PubWeight™ 38.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell 2009 3.63
2 Rapamycin extends murine lifespan but has limited effects on aging. J Clin Invest 2013 2.23
3 A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol 2013 2.04
4 Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice. Gastroenterology 2004 1.99
5 Targeted estrogen delivery reverses the metabolic syndrome. Nat Med 2012 1.51
6 Mouse phenotyping. Methods 2010 1.43
7 ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta. PLoS Genet 2008 1.37
8 Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. J Biol Chem 2014 1.37
9 Systemic first-line phenotyping. Methods Mol Biol 2009 1.26
10 Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Sci 2011 1.24
11 Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet 2012 1.09
12 Innovations in phenotyping of mouse models in the German Mouse Clinic. Mamm Genome 2012 1.09
13 Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. J Biol Chem 2011 1.05
14 A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis Rheum 2011 1.04
15 Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism. Am J Physiol Renal Physiol 2009 1.02
16 Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. Am J Physiol Renal Physiol 2010 0.93
17 Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice. Hum Mol Genet 2013 0.93
18 A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice. PLoS One 2013 0.89
19 Microphthalmia, parkinsonism, and enhanced nociception in Pitx3 ( 416insG ) mice. Mamm Genome 2009 0.89
20 New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. Mamm Genome 2012 0.88
21 Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology. FASEB J 2012 0.87
22 Pleiotropic effects in Eya3 knockout mice. BMC Dev Biol 2008 0.86
23 SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA Repair (Amst) 2013 0.86
24 Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS One 2009 0.85
25 Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms. Hum Mol Genet 2012 0.85
26 New ENU-induced semidominant mutation, Ali18, causes inflammatory arthritis, dermatitis, and osteoporosis in the mouse. Mamm Genome 2006 0.84
27 Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans. PLoS Genet 2012 0.83
28 Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. PLoS One 2013 0.82
29 Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice. PLoS One 2013 0.80
30 An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease. Am J Pathol 2013 0.78
31 Modeling hepatic osteodystrophy in Abcb4 deficient mice. Bone 2013 0.77
32 Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice. J Biomed Sci 2014 0.77
33 Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines. Eur J Oral Sci 2012 0.76
34 Long-term experiment to study the development, interaction, and influencing factors of DEXA parameters. Mamm Genome 2013 0.76
35 Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels. Biometals 2015 0.75