Published in PLoS One on August 21, 2012
Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl. Blood (2014) 1.40
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing. Cell Rep (2015) 1.16
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. Elife (2015) 0.84
PHD and TFIIS-Like domains of the Bye1 transcription factor determine its multivalent genomic distribution. PLoS One (2014) 0.77
MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer (2007) 8.17
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet (2002) 5.55
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev (2003) 4.73
Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr Opin Cell Biol (2008) 4.25
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell (2005) 3.70
Actin' together: serum response factor, its cofactors and the link to signal transduction. Trends Cell Biol (2006) 3.65
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest (2006) 3.27
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem (2005) 2.86
Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol Cell Biol (2003) 2.73
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes Dev (2001) 2.68
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet (2001) 2.55
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia. Genes Dev (2008) 2.41
Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. Proc Natl Acad Sci U S A (2001) 2.35
SHARP is a novel component of the Notch/RBP-Jkappa signalling pathway. EMBO J (2002) 2.26
Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex. J Biol Chem (2007) 2.24
SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. Mol Cell (1999) 1.93
A COMPASS in the voyage of defining the role of trithorax/MLL-containing complexes: linking leukemogensis to covalent modifications of chromatin. J Cell Biochem (2005) 1.88
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes. Mol Cell Biol (2007) 1.58
The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model. J Clin Invest (2009) 1.44
spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk. Development (1999) 1.42
A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling. Genes Dev (2003) 1.40
MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia. Gene (2002) 1.36
split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo. Development (2000) 1.36
MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. Oncogene (1999) 1.35
Ott1(Rbm15) has pleiotropic roles in hematopoietic development. Proc Natl Acad Sci U S A (2007) 1.29
Rbm15 modulates Notch-induced transcriptional activation and affects myeloid differentiation. Mol Cell Biol (2007) 1.26
The t(1;22) (p13;q13) is nonrandom and restricted to infants with acute megakaryoblastic leukemia: a Pediatric Oncology Group Study. Blood (1991) 1.23
Role for MKL1 in megakaryocytic maturation. Blood (2009) 1.19
RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway. J Biol Chem (2006) 1.14
CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals. J Biol Chem (2002) 1.13
Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export. J Biol Chem (2005) 1.13
Identification and characterization of a novel human PP1 phosphatase complex. J Biol Chem (2010) 1.09
The human trithorax protein hASH2 functions as an oncoprotein. Cancer Res (2008) 1.08
The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1. J Biol Chem (2009) 1.06
Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells? Int J Hematol (2010) 0.98
OTT-MAL is a deregulated activator of serum response factor-dependent gene expression. Mol Cell Biol (2008) 0.96
Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA. Nucleic Acids Res (2009) 0.96
c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development. Blood (2009) 0.95
SPOC: a widely distributed domain associated with cancer, apoptosis and transcription. BMC Bioinformatics (2004) 0.95
Biology, clinical, and hematologic features of acute megakaryoblastic leukemia in children. Am J Hematol (2003) 0.92
Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen. Mol Cell Biol (2008) 0.89
Fusion of OTT to BSAC results in aberrant up-regulation of transcriptional activity. J Biol Chem (2008) 0.84
Histone deacetylase activity is required for embryonic stem cell differentiation. Genesis (2004) 3.07
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem (2005) 2.86
Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex. J Biol Chem (2007) 2.24
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes. Mol Cell Biol (2007) 1.58
DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells. DNA Cell Biol (2009) 1.44
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer. Mol Cancer Ther (2005) 1.40
Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein. Mol Cell Biol (2005) 1.26
CpG-binding protein is a nuclear matrix- and euchromatin-associated protein localized to nuclear speckles containing human trithorax. Identification of nuclear matrix targeting signals. J Biol Chem (2002) 1.13
Identification and characterization of a novel human PP1 phosphatase complex. J Biol Chem (2010) 1.09
Dynamic loss of H2B ubiquitylation without corresponding changes in H3K4 trimethylation during myogenic differentiation. Mol Cell Biol (2012) 1.06
Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J Biol Chem (2012) 1.04
CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin. FEBS J (2009) 1.01
CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation. Mol Cell Biol (2009) 1.00
Methyl group acceptance assay for the determination of global DNA methylation levels. Methods Mol Biol (2009) 0.95
Antisense targeting of CXXC finger protein 1 inhibits genomic cytosine methylation and primitive hematopoiesis in zebrafish. J Biol Chem (2006) 0.85
CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes. DNA Cell Biol (2008) 0.85
CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB-985 myeloid cell line. DNA Cell Biol (2007) 0.85
The human immunodeficiency virus protease inhibitor ritonavir inhibits lung cancer cells, in part, by inhibition of survivin. J Thorac Oncol (2011) 0.80
Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation. Gene (2009) 0.80
Cloning and characterization of the gene encoding the mouse homologue of CpG binding protein. Gene (2002) 0.80
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity. DNA Repair (Amst) (2009) 0.75
Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity. DNA Repair (Amst) (2003) 0.75
PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity. J Biochem Biophys Methods (2006) 0.75
The epigenetic regulator Cfp1. Biomol Concepts (2010) 0.75