Published in Angew Chem Int Ed Engl on August 28, 2012
Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs). Br J Pharmacol (2014) 1.02
Emerging concepts on the anti-inflammatory actions of carbon monoxide-releasing molecules (CO-RMs). Med Gas Res (2012) 0.98
CO-releasing Metal Carbonyl Compounds as Antimicrobial Agents in the Post-antibiotic Era. J Biol Chem (2015) 0.87
Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments. Biochim Biophys Acta (2013) 0.86
Carbon monoxide--physiology, detection and controlled release. Chem Commun (Camb) (2014) 0.85
Gasotransmitters, poisons, and antimicrobials: it's a gas, gas, gas! F1000Prime Rep (2013) 0.80
Carbon monoxide-releasing molecule-3 (CORM-3; Ru(CO)3Cl(glycinate)) as a tool to study the concerted effects of carbon monoxide and nitric oxide on bacterial flavohemoglobin Hmp: applications and pitfalls. J Biol Chem (2014) 0.77
Lighting up carbon monoxide: fluorescent probes for monitoring CO in living cells. Angew Chem Int Ed Engl (2012) 0.77
A minimalist fluorescent probe for differentiating Cys, Hcy and GSH in live cells. Chem Sci (2015) 0.77
The Heme Metabolite Carbon Monoxide Facilitates KSHV Infection by Inhibiting TLR4 Signaling in Endothelial Cells. Front Microbiol (2017) 0.75
A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells. Chem Commun (Camb) (2013) 0.75
Fluorescent probes for imaging formaldehyde in biological systems. Curr Opin Chem Biol (2017) 0.75
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science (2011) 14.29
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (2011) 13.16
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell (2011) 7.37
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell (2012) 7.09
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol (2011) 5.96
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell (2012) 4.18
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat Neurosci (2011) 4.15
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell (2013) 3.13
Gold-catalyzed organic transformations. Chem Rev (2008) 3.06
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet (2011) 2.87
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett (2008) 2.61
Balloon guide catheter improves revascularization and clinical outcomes with the Solitaire device: analysis of the North American Solitaire Acute Stroke Registry. Stroke (2013) 2.46
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol (2012) 2.45
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell (2012) 2.39
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res (2011) 2.36
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature (2008) 2.30
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat Chem Biol (2008) 2.04
Reversible RNA adenosine methylation in biological regulation. Trends Genet (2012) 1.93
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine. Nat Methods (2011) 1.90
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol (2006) 1.83
Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA. Org Lett (2011) 1.82
A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol (2008) 1.80
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl (2010) 1.76
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A (2013) 1.70
5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. Nat Struct Mol Biol (2012) 1.67
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc (2012) 1.66
Brønsted acid catalyzed addition of phenols, carboxylic acids, and tosylamides to simple olefins. Org Lett (2006) 1.63
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell (2012) 1.61
A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli. Nat Methods (2007) 1.54
Selective fluorescent probes for live-cell monitoring of sulphide. Nat Commun (2011) 1.51
A non-heme iron-mediated chemical demethylation in DNA and RNA. Acc Chem Res (2009) 1.51
Mapping recently identified nucleotide variants in the genome and transcriptome. Nat Biotechnol (2012) 1.51
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins. J Am Chem Soc (2005) 1.50
A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. Nat Chem Biol (2011) 1.47
The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proc Natl Acad Sci U S A (2008) 1.39
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA. RNA (2013) 1.37
Mechanism and function of oxidative reversal of DNA and RNA methylation. Annu Rev Biochem (2014) 1.36
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biol (2014) 1.36
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature (2010) 1.36
In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS. J Bacteriol (2010) 1.35
Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA (2010) 1.33
Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A (2009) 1.31
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol (2013) 1.27
The structure of the human AGT protein bound to DNA and its implications for damage detection. J Mol Biol (2005) 1.26
A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus. Mol Microbiol (2008) 1.25
Enhanced 5-methylcytosine detection in single-molecule, real-time sequencing via Tet1 oxidation. BMC Biol (2013) 1.24
B-1 cells in the bone marrow are a significant source of natural IgM. Eur J Immunol (2011) 1.23
Direct reversal of DNA alkylation damage. Chem Rev (2006) 1.22
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus. J Biol Chem (2009) 1.21
Efficient functionalization of aromatic C-H bonds catalyzed by gold(III) under mild and solvent-free conditions. J Org Chem (2004) 1.21
Potential functional roles of DNA demethylation intermediates. Trends Biochem Sci (2013) 1.21
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum Mol Genet (2012) 1.21
Quantitative genetic background of the host influences gut microbiomes in chickens. Sci Rep (2013) 1.20
Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol (2012) 1.20
TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A (2013) 1.19
High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing. Angew Chem Int Ed Engl (2014) 1.18
Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis. Nat Commun (2013) 1.18
Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc Natl Acad Sci U S A (2012) 1.18
Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. J Bacteriol (2010) 1.18
Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli. J Am Chem Soc (2004) 1.16
A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions. J Am Chem Soc (2004) 1.16
High-purity prostate circulating tumor cell isolation by a polymer nanofiber-embedded microchip for whole exome sequencing. Adv Mater (2013) 1.16
Selective recognition of metal ions by metalloregulatory proteins. Curr Opin Chem Biol (2008) 1.16
Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states. J Biol Chem (2011) 1.15
A silver-catalyzed intramolecular amidation of saturated C--h bonds. Angew Chem Int Ed Engl (2004) 1.15
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. J Inorg Biochem (2006) 1.15
Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs). J Pharm Sci (2006) 1.15
A genetically encoded epsilon-N-methyl lysine in mammalian cells. Chembiochem (2010) 1.12
Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA. Proc Natl Acad Sci U S A (2012) 1.11
Gold(I)-catalyzed intra- and intermolecular hydroamination of unactivated olefins. J Am Chem Soc (2006) 1.11
Aureusimines in Staphylococcus aureus are not involved in virulence. PLoS One (2010) 1.11
FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun (2013) 1.10
Silver-catalyzed intermolecular amination of C--H groups. Angew Chem Int Ed Engl (2007) 1.10
Introducing bioorthogonal functionalities into proteins in living cells. Acc Chem Res (2011) 1.10
Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Mol Microbiol (2009) 1.09
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun (2013) 1.08
Spatiotemporal clustering of the epigenome reveals rules of dynamic gene regulation. Genome Res (2012) 1.08
Gold(I)-catalyzed intermolecular addition of phenols and carboxylic acids to olefins. J Am Chem Soc (2005) 1.07
Genome sequences of wild and domestic bactrian camels. Nat Commun (2012) 1.07
Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA. J Org Chem (2011) 1.07
Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol (2008) 1.06
Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe (2013) 1.06
Organocatalysis in cross-coupling: DMEDA-catalyzed direct C-H arylation of unactivated benzene. J Am Chem Soc (2010) 1.05
NanoVelcro Chip for CTC enumeration in prostate cancer patients. Methods (2013) 1.05
Transition metal-mediated bioorthogonal protein chemistry in living cells. Chem Soc Rev (2014) 1.05
Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc Natl Acad Sci U S A (2014) 1.04
AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus. J Am Chem Soc (2011) 1.04
Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+. J Am Chem Soc (2007) 1.03
Chemical modification-assisted bisulfite sequencing (CAB-Seq) for 5-carboxylcytosine detection in DNA. J Am Chem Soc (2013) 1.03
Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor. J Am Chem Soc (2010) 1.03
Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking. J Am Chem Soc (2003) 1.01
Nucleic acid oxidation in DNA damage repair and epigenetics. Chem Rev (2014) 1.01
An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe. Angew Chem Int Ed Engl (2005) 1.00
Stabilization of human papillomavirus virus-like particles by non-ionic surfactants. J Pharm Sci (2005) 1.00
Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies. Nucleic Acids Res (2004) 1.00