Published in PLoS One on September 05, 2012
The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning. Neuron (2016) 1.48
Activation of transposable elements during aging and neuronal decline in Drosophila. Nat Neurosci (2013) 1.43
Mobile DNA elements in the generation of diversity and complexity in the brain. Nat Rev Neurosci (2014) 1.35
The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs. RNA (2014) 1.06
Transcriptional landscape of repetitive elements in normal and cancer human cells. BMC Genomics (2014) 1.01
The role of transposable elements in health and diseases of the central nervous system. J Neurosci (2013) 1.01
Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions. Genome Biol (2014) 1.00
Retroviruses and amyotrophic lateral sclerosis. Antiviral Res (2013) 0.94
TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets. Bioinformatics (2015) 0.94
Stress and the dynamic genome: Steroids, epigenetics, and the transposome. Proc Natl Acad Sci U S A (2014) 0.89
The RNA-centred view of the synapse: non-coding RNAs and synaptic plasticity. Philos Trans R Soc Lond B Biol Sci (2014) 0.89
Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity. Front Neurosci (2015) 0.79
TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA. EMBO J (2014) 0.77
RNA interference machinery-mediated gene regulation in mouse adult neural stem cells. BMC Neurosci (2015) 0.76
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain. Proc Natl Acad Sci U S A (2016) 0.75
Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS. PLoS Genet (2017) 0.75
Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder. Sci Rep (2016) 0.75
Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes. Nucleus (2017) 0.75
Transposable elements in Drosophila. Mob Genet Elements (2017) 0.75
STEAK: A specific tool for transposable elements and retrovirus detection in high-throughput sequencing data. Virus Evol (2017) 0.75
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. Nucleic Acids Res (2017) 0.75
DNA strand breaks and TDP-43 mislocation are absent in the murine hSOD1G93A model of amyotrophic lateral sclerosis in vivo and in vitro. PLoS One (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Differential expression analysis for sequence count data. Genome Biol (2010) 64.56
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
Repbase Update, a database of eukaryotic repetitive elements. Cytogenet Genome Res (2005) 23.41
The UCSC Genome Browser database: update 2011. Nucleic Acids Res (2010) 16.24
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science (2009) 12.99
PeakSeq enables systematic scoring of ChIP-seq experiments relative to controls. Nat Biotechnol (2009) 11.28
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature (2005) 6.95
MEME-ChIP: motif analysis of large DNA datasets. Bioinformatics (2011) 6.52
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat Struct Mol Biol (2009) 6.37
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci (2011) 6.01
Repetitive DNA and next-generation sequencing: computational challenges and solutions. Nat Rev Genet (2011) 5.58
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. Nat Neurosci (2011) 5.24
L1 retrotransposition in human neural progenitor cells. Nature (2009) 4.78
Somatic retrotransposition alters the genetic landscape of the human brain. Nature (2011) 4.16
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature (2011) 3.90
Active human retrotransposons: variation and disease. Curr Opin Genet Dev (2012) 3.60
L1 retrotransposition in neurons is modulated by MeCP2. Nature (2010) 3.25
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes. J Biol Chem (2010) 2.72
Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Curr Opin Neurobiol (2011) 2.48
iCLIP predicts the dual splicing effects of TIA-RNA interactions. PLoS Biol (2010) 2.39
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci U S A (2010) 1.92
The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation. RNA Biol (2010) 1.66
The struggle for life of the genome's selfish architects. Biol Direct (2011) 1.64
Small RNA-mediated quiescence of transposable elements in animals. Dev Cell (2010) 1.63
Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus (2009) 1.62
TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies. Trends Mol Med (2011) 1.38
RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS. Mol Cell Neurosci (2011) 1.38
Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis. Ann Neurol (2011) 1.21
BM-map: Bayesian mapping of multireads for next-generation sequencing data. Biometrics (2011) 1.11
The prevalence of human endogenous retroviruses in cerebrospinal fluids from patients with sporadic Creutzfeldt-Jakob disease. J Clin Virol (2009) 1.02
Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration. Hum Mol Genet (2011) 0.92
TDP-43: multiple targets, multiple disease mechanisms? Nat Neurosci (2011) 0.89
Differential display detects host nucleic acid motifs altered in scrapie-infected brain. J Mol Biol (2009) 0.86
Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis). Mol Neurodegener (2011) 0.86
Expression profiles of endogenous retroviruses in Old World monkeys. J Virol (2006) 0.83
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. Genes Dev (2008) 3.19
Pax6 is a human neuroectoderm cell fate determinant. Cell Stem Cell (2010) 2.46
Deconstructing memory in Drosophila. Curr Biol (2005) 2.41
Short- and long-term memory in Drosophila require cAMP signaling in distinct neuron types. Curr Biol (2009) 2.23
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. J Neurosci (2013) 2.04
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells. Cell Res (2009) 1.97
Multiple roles for Piwi in silencing Drosophila transposons. Genes Dev (2013) 1.96
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood (2011) 1.83
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. J Neurosci (2010) 1.57
A flagellar polycystin-2 homolog required for male fertility in Drosophila. Curr Biol (2003) 1.56
Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. Hum Mol Genet (2009) 1.54
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination. J Biol Chem (2004) 1.53
Ascorbic acid enhances the cardiac differentiation of induced pluripotent stem cells through promoting the proliferation of cardiac progenitor cells. Cell Res (2011) 1.47
Phytate, calcium, iron, and zinc contents and their molar ratios in foods commonly consumed in China. J Agric Food Chem (2005) 1.43
ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein. FASEB J (2006) 1.43
Activation of transposable elements during aging and neuronal decline in Drosophila. Nat Neurosci (2013) 1.43
Transcriptome analysis of early organogenesis in human embryos. Dev Cell (2010) 1.37
Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes. Invest Ophthalmol Vis Sci (2008) 1.32
Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila. Proc Natl Acad Sci U S A (2011) 1.27
Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proc Natl Acad Sci U S A (2009) 1.26
Changes of higher order aberration with various pupil sizes in the myopic eye. J Refract Surg (2003) 1.26
Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear. Proc Natl Acad Sci U S A (2010) 1.25
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. J Biol Chem (2004) 1.24
Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes. Cell Res (2013) 1.24
An ultra-short dopamine pathway regulates basal ganglia output. J Neurosci (2009) 1.23
Facilitating Akt clearance via manipulation of Hsp70 activity and levels. J Biol Chem (2009) 1.22
CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut (2012) 1.17
Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP. J Invest Dermatol (2010) 1.14
Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development (2009) 1.14
CREB and the discovery of cognitive enhancers. J Mol Neurosci (2002) 1.14
NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome. Proc Natl Acad Sci U S A (2013) 1.12
Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proc Natl Acad Sci U S A (2010) 1.12
Role of Oct4 in maintaining and regaining stem cell pluripotency. Stem Cell Res Ther (2010) 1.12
Effect of life history on microRNA expression during C. elegans development. RNA (2011) 1.11
Critical roles of coactivator p300 in mouse embryonic stem cell differentiation and Nanog expression. J Biol Chem (2009) 1.10
Calcineurin-NFAT signaling critically regulates early lineage specification in mouse embryonic stem cells and embryos. Cell Stem Cell (2011) 1.10
Identification of synaptic targets of Drosophila pumilio. PLoS Comput Biol (2008) 1.10
Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line. Eur J Pharmacol (2010) 1.09
Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells. Mol Cell Biol (2007) 1.08
Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1. FASEB J (2007) 1.08
Ethanol sensitivity and tolerance in long-term memory mutants of Drosophila melanogaster. Alcohol Clin Exp Res (2008) 1.08
PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation. J Biol Chem (2009) 1.08
Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner. Cell Res (2009) 1.08
Next-generation DNA re-sequencing identifies common variants of TYR and HLA-A that modulate the risk of generalized vitiligo via antigen presentation. J Invest Dermatol (2012) 1.07
Temporal and parental-specific expression of imprinted genes in a newly derived Chinese human embryonic stem cell line and embryoid bodies. Hum Mol Genet (2005) 1.07
Imbalance of Hsp70 family variants fosters tau accumulation. FASEB J (2012) 1.07
Activation of paternally expressed imprinted genes in newly derived germline-competent mouse parthenogenetic embryonic stem cell lines. Cell Res (2007) 1.07
Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein. J Biol Chem (2003) 1.06
Hsc70 rapidly engages tau after microtubule destabilization. J Biol Chem (2010) 1.06
Isolation and analysis of water stress induced genes in maize seedlings by subtractive PCR and cDNA macroarray. Plant Mol Biol (2004) 1.04
Dual functions of T-box 3 (Tbx3) in the control of self-renewal and extraembryonic endoderm differentiation in mouse embryonic stem cells. J Biol Chem (2010) 1.04
Is Rasch model analysis applicable in small sample size pilot studies for assessing item characteristics? An example using PROMIS pain behavior item bank data. Qual Life Res (2013) 1.04
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau. Biol Psychiatry (2013) 1.03
Targeting axon growth from neuronal transplants along preformed guidance pathways in the adult CNS. J Neurosci (2008) 1.03
Reprogramming of somatic cells via TAT-mediated protein transduction of recombinant factors. Biomaterials (2012) 1.02
Germline-competent mouse-induced pluripotent stem cell lines generated on human fibroblasts without exogenous leukemia inhibitory factor. PLoS One (2009) 1.01
E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation. Proc Natl Acad Sci U S A (2013) 1.00
Expression of Gpr177, a Wnt trafficking regulator, in mouse embryogenesis. Dev Dyn (2010) 1.00
WNT signaling determines tumorigenicity and function of ESC-derived retinal progenitors. J Clin Invest (2013) 1.00
Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. Hum Mol Genet (2008) 1.00
Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear. J Neurosci (2013) 0.99
Mode of action of taurine as a neuroprotector. Brain Res (2005) 0.99
Ly-1 antibody reactive clone is an important nucleolar protein for control of self-renewal and differentiation in embryonic stem cells. Stem Cells (2009) 0.98
Ionic dysregulatory phenotyping of pathologic retinal thinning with manganese-enhanced MRI. Invest Ophthalmol Vis Sci (2008) 0.98
A versatile and efficient ligand for copper-catalyzed formation of C-N, C-O, and P-C bonds: pyrrolidine-2-phosphonic acid phenyl monoester. Chemistry (2006) 0.98
HER2-positive patients receiving trastuzumab treatment have a comparable prognosis with HER2-negative advanced gastric cancer patients: a prospective cohort observation. Int J Cancer (2013) 0.97
Influence of iodine on the reference interval of TSH and the optimal interval of TSH: results of a follow-up study in areas with different iodine intakes. Clin Endocrinol (Oxf) (2008) 0.97
Protective function of taurine in glutamate-induced apoptosis in cultured neurons. J Neurosci Res (2009) 0.96
Sample size and power estimates for a confirmatory factor analytic model in exercise and sport: a Monte Carlo approach. Res Q Exerc Sport (2011) 0.96
Iron and zinc deficiencies in China: what is a feasible and cost-effective strategy? Public Health Nutr (2007) 0.96
Identification of karyopherin-alpha 2 as an Oct4 associated protein. J Genet Genomics (2008) 0.96
An atlas of chromatoid body components. RNA (2014) 0.95
Large scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells. Mol Cell Proteomics (2010) 0.94
Serum C-reactive protein as an important prognostic variable in patients with diffuse large B cell lymphoma. Tumour Biol (2012) 0.94
The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation. J Biol Chem (2004) 0.94
Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma. J Transl Med (2012) 0.93
Toward clinical application of manganese-enhanced MRI of retinal function. Brain Res Bull (2009) 0.93
Role of glutamate decarboxylase (GAD) isoform, GAD65, in GABA synthesis and transport into synaptic vesicles-Evidence from GAD65-knockout mice studies. Brain Res (2007) 0.93
Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell Rep (2013) 0.92
DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. J Mol Biol (2012) 0.92
Ethics: China already has clear stem-cell guidelines. Nature (2006) 0.91
Sphingolipids as new biomarkers for assessment of delayed-type hypersensitivity and response to triptolide. PLoS One (2012) 0.91
The neuroprotective effects of Coccomyxa gloeobotrydiformis on the ischemic stroke in a rat model. Int J Biol Sci (2013) 0.90
Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway. J Biol Chem (2011) 0.90
Assessment of intake inadequacy and food sources of zinc of people in China. Public Health Nutr (2007) 0.90
Lauren classification combined with HER2 status is a better prognostic factor in Chinese gastric cancer patients. BMC Cancer (2014) 0.90
Comparison of clinicopathological characteristics and prognoses between bilateral and unilateral breast cancer. J Cancer Res Clin Oncol (2012) 0.90
Derivation and transcriptional profiling analysis of pluripotent stem cell lines from rat blastocysts. Cell Res (2009) 0.90
NELF potentiates gene transcription in the Drosophila embryo. PLoS One (2010) 0.89
Inducible and reversible suppression of Npm1 gene expression using stably integrated small interfering RNA vector in mouse embryonic stem cells. Biochem Biophys Res Commun (2006) 0.89
Differences in optical properties between healthy and pathological human colon tissues using a Ti:sapphire laser: an in vitro study using the Monte Carlo inversion technique. J Biomed Opt (2005) 0.88
Comparison of microRNA expression in hippocampus and the marginal division (MrD) of the neostriatum in rats. J Biomed Sci (2013) 0.88
Itch, an E3 ligase of Oct4, is required for embryonic stem cell self-renewal and pluripotency induction. J Cell Physiol (2013) 0.88
Genotypic analysis on the ORF-K1 gene of human herpesvirus 8 from patients with Kaposi's sarcoma in Xinjiang, China. J Genet Genomics (2008) 0.87
Efficient derivation of Chinese human embryonic stem cell lines from frozen embryos. In Vitro Cell Dev Biol Anim (2010) 0.87
Implications of poly(N-isopropylacrylamide)-g-poly(ethylene glycol) with codissolved brain-derived neurotrophic factor injectable scaffold on motor function recovery rate following cervical dorsolateral funiculotomy in the rat. J Neurosurg Spine (2013) 0.87