Published in Infect Immun on September 10, 2012
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Fine mapping of the N-terminal cytotoxicity region of Clostridium perfringens enterotoxin by site-directed mutagenesis. Infect Immun (2004) 1.01
Noncytotoxic Clostridium perfringens enterotoxin (CPE) variants localize CPE intestinal binding and demonstrate a relationship between CPE-induced cytotoxicity and enterotoxicity. Infect Immun (2008) 0.99
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Comparative metagenomics reveals host specific metavirulomes and horizontal gene transfer elements in the chicken cecum microbiome. PLoS One (2008) 1.86
Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model. Mol Microbiol (2008) 1.78
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Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model. Infect Immun (2005) 1.49
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Multiplex PCR genotyping assay that distinguishes between isolates of Clostridium perfringens type A carrying a chromosomal enterotoxin gene (cpe) locus, a plasmid cpe locus with an IS1470-like sequence, or a plasmid cpe locus with an IS1151 sequence. J Clin Microbiol (2004) 1.40
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Use of an EZ-Tn5-based random mutagenesis system to identify a novel toxin regulatory locus in Clostridium perfringens strain 13. PLoS One (2009) 1.34
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Development of a duplex PCR genotyping assay for distinguishing Clostridium perfringens type A isolates carrying chromosomal enterotoxin (cpe) genes from those carrying plasmid-borne enterotoxin (cpe) genes. J Clin Microbiol (2003) 1.31
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A novel small acid soluble protein variant is important for spore resistance of most Clostridium perfringens food poisoning isolates. PLoS Pathog (2008) 1.27
Comparison of virulence plasmids among Clostridium perfringens type E isolates. Infect Immun (2007) 1.24
The Agr-like quorum-sensing system regulates sporulation and production of enterotoxin and beta2 toxin by Clostridium perfringens type A non-food-borne human gastrointestinal disease strain F5603. Infect Immun (2011) 1.23
Identification of a prepore large-complex stage in the mechanism of action of Clostridium perfringens enterotoxin. Infect Immun (2007) 1.23
Comparative effects of osmotic, sodium nitrite-induced, and pH-induced stress on growth and survival of Clostridium perfringens type A isolates carrying chromosomal or plasmid-borne enterotoxin genes. Appl Environ Microbiol (2006) 1.18
Compositional and stoichiometric analysis of Clostridium perfringens enterotoxin complexes in Caco-2 cells and claudin 4 fibroblast transfectants. Cell Microbiol (2007) 1.17
Epsilon-toxin plasmids of Clostridium perfringens type D are conjugative. J Bacteriol (2007) 1.16
Genetic characterization of type A enterotoxigenic Clostridium perfringens strains. PLoS One (2009) 1.16
Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model. Infect Immun (2007) 1.15
Prevalence of enterotoxigenic Clostridium perfringens Isolates in Pittsburgh (Pennsylvania) area soils and home kitchens. Appl Environ Microbiol (2007) 1.15
Characterization of virulence plasmid diversity among Clostridium perfringens type B isolates. Infect Immun (2009) 1.14
Death pathways activated in CaCo-2 cells by Clostridium perfringens enterotoxin. Infect Immun (2003) 1.14
Clostridium perfringens toxin genotypes in the feces of healthy North Americans. Anaerobe (2008) 1.12
Sequencing and diversity analyses reveal extensive similarities between some epsilon-toxin-encoding plasmids and the pCPF5603 Clostridium perfringens enterotoxin plasmid. J Bacteriol (2008) 1.11
The importance of calcium influx, calpain and calmodulin for the activation of CaCo-2 cell death pathways by Clostridium perfringens enterotoxin. Cell Microbiol (2005) 1.11
Evaluating the involvement of alternative sigma factors SigF and SigG in Clostridium perfringens sporulation and enterotoxin synthesis. Infect Immun (2010) 1.10
Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias. Infect Immun (2009) 1.10
Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis. Cancer Res (2007) 1.07
Toxin plasmids of Clostridium perfringens. Microbiol Mol Biol Rev (2013) 1.07
Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease. Future Microbiol (2014) 1.07
Characterization of toxin plasmids in Clostridium perfringens type C isolates. Infect Immun (2010) 1.05
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Structure of the food-poisoning Clostridium perfringens enterotoxin reveals similarity to the aerolysin-like pore-forming toxins. J Mol Biol (2011) 1.02
Fine mapping of the N-terminal cytotoxicity region of Clostridium perfringens enterotoxin by site-directed mutagenesis. Infect Immun (2004) 1.01
Evidence that the Agr-like quorum sensing system regulates the toxin production, cytotoxicity and pathogenicity of Clostridium perfringens type C isolate CN3685. Mol Microbiol (2011) 1.01
Evidence for a prepore stage in the action of Clostridium perfringens epsilon toxin. PLoS One (2011) 1.01
Noncytotoxic Clostridium perfringens enterotoxin (CPE) variants localize CPE intestinal binding and demonstrate a relationship between CPE-induced cytotoxicity and enterotoxicity. Infect Immun (2008) 0.99
Identification of a claudin-4 residue important for mediating the host cell binding and action of Clostridium perfringens enterotoxin. Infect Immun (2009) 0.98
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Identification of novel Clostridium perfringens type E strains that carry an iota toxin plasmid with a functional enterotoxin gene. PLoS One (2011) 0.97
CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718. MBio (2013) 0.95
Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection. Infect Immun (2007) 0.94
Further characterization of Clostridium perfringens small acid soluble protein-4 (Ssp4) properties and expression. PLoS One (2009) 0.93
Use of Clostridium perfringens Enterotoxin and the Enterotoxin Receptor-Binding Domain (C-CPE) for Cancer Treatment: Opportunities and Challenges. J Toxicol (2011) 0.92
Human claudin-8 and -14 are receptors capable of conveying the cytotoxic effects of Clostridium perfringens enterotoxin. MBio (2013) 0.92
Role of the Agr-like quorum-sensing system in regulating toxin production by Clostridium perfringens type B strains CN1793 and CN1795. Infect Immun (2012) 0.92
Genotypic and phenotypic characterization of Clostridium perfringens isolates from Darmbrand cases in post-World War II Germany. Infect Immun (2012) 0.91
Development and application of a mouse intestinal loop model to study the in vivo action of Clostridium perfringens enterotoxin. Infect Immun (2011) 0.91
Clostridium perfringens epsilon toxin increases the small intestinal permeability in mice and rats. PLoS One (2009) 0.90
Organization of the cpe locus in CPE-positive clostridium perfringens type C and D isolates. PLoS One (2010) 0.89
Detection of enterotoxigenic Clostridium perfringens in meat samples by using molecular methods. Appl Environ Microbiol (2011) 0.86
Enterotoxigenic Clostridium perfringens: detection and identification. Microbes Environ (2012) 0.83
Clostridium perfringens type A enterotoxin damages the rabbit colon. Infect Immun (2014) 0.83
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Identification of a lambda toxin-negative Clostridium perfringens strain that processes and activates epsilon prototoxin intracellularly. Anaerobe (2012) 0.82
The Sialidases of Clostridium perfringens type D strain CN3718 differ in their properties and sensitivities to inhibitors. Appl Environ Microbiol (2013) 0.82
Evidence that membrane rafts are not required for the action of Clostridium perfringens enterotoxin. Infect Immun (2008) 0.81
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Crystallization and preliminary crystallographic analysis of the Clostridium perfringens enterotoxin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.79
Animal models to study the pathogenesis of enterotoxigenic Clostridium perfringens infections. Microbes Infect (2012) 0.79
Phenotypic and genotypic characterization of tetracycline and minocycline resistance in Clostridium perfringens. Arch Microbiol (2010) 0.78
Clostridium perfringens Sporulation and Sporulation-Associated Toxin Production. Microbiol Spectr (2016) 0.78
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Virulence for chickens of Clostridium perfringens isolated from poultry and other sources. Anaerobe (2010) 0.77
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Ulcerative enteritis-like disease associated with Clostridium perfringens type A in bobwhite quail (Colinus virginianus). Avian Dis (2008) 0.75