Published in J Bacteriol on August 24, 2007
Genetic characterization of type A enterotoxigenic Clostridium perfringens strains. PLoS One (2009) 1.16
Characterization of virulence plasmid diversity among Clostridium perfringens type B isolates. Infect Immun (2009) 1.14
Sequencing and diversity analyses reveal extensive similarities between some epsilon-toxin-encoding plasmids and the pCPF5603 Clostridium perfringens enterotoxin plasmid. J Bacteriol (2008) 1.11
Conjugative botulinum neurotoxin-encoding plasmids in Clostridium botulinum. PLoS One (2010) 1.08
Toxin plasmids of Clostridium perfringens. Microbiol Mol Biol Rev (2013) 1.07
Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease. Future Microbiol (2014) 1.07
Characterization of toxin plasmids in Clostridium perfringens type C isolates. Infect Immun (2010) 1.05
The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence. Infect Immun (2009) 1.02
Clostridium Perfringens Toxins Involved in Mammalian Veterinary Diseases. Open Toxinology J (2010) 1.01
Functional characterization and localization of the TcpH conjugation protein from Clostridium perfringens. J Bacteriol (2008) 0.98
Necrotic enteritis-derived Clostridium perfringens strain with three closely related independently conjugative toxin and antibiotic resistance plasmids. MBio (2011) 0.98
Epsilon toxin is essential for the virulence of Clostridium perfringens type D infection in sheep, goats, and mice. Infect Immun (2013) 0.94
The putative coupling protein TcpA interacts with other pCW3-encoded proteins to form an essential part of the conjugation complex. J Bacteriol (2009) 0.93
Genotypic and phenotypic characterization of Clostridium perfringens isolates from Darmbrand cases in post-World War II Germany. Infect Immun (2012) 0.91
tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens. J Bacteriol (2009) 0.84
Identification of accessory genome regions in poultry Clostridium perfringens isolates carrying the netB plasmid. J Bacteriol (2013) 0.84
Identification of a lambda toxin-negative Clostridium perfringens strain that processes and activates epsilon prototoxin intracellularly. Anaerobe (2012) 0.82
Clostridium perfringens type A-E toxin plasmids. Res Microbiol (2014) 0.78
Two novel membrane proteins, TcpD and TcpE, are essential for conjugative transfer of pCW3 in Clostridium perfringens. J Bacteriol (2014) 0.76
Plasmid Characterization and Chromosome Analysis of Two netF+ Clostridium perfringens Isolates Associated with Foal and Canine Necrotizing Enteritis. PLoS One (2016) 0.75
The NEAT Domain-Containing Proteins of Clostridium perfringens Bind Heme. PLoS One (2016) 0.75
Clostridial enteric diseases of domestic animals. Clin Microbiol Rev (1996) 4.97
Molecular genetics and pathogenesis of Clostridium perfringens. Microbiol Rev (1991) 3.81
Clostridium perfringens: toxinotype and genotype. Trends Microbiol (1999) 3.21
Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol (2006) 2.65
Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringens. Mol Microbiol (1994) 2.37
Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier. Mol Microbiol (2002) 2.19
Occurrence of Clostridium perfringens beta2-toxin amongst animals, determined using genotyping and subtyping PCR assays. Epidemiol Infect (2000) 2.18
Isolation and characterization of multiply antibiotic-resistant Clostridum perfringens strains from porcine feces. Antimicrob Agents Chemother (1978) 2.11
Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringens. Mol Microbiol (1992) 2.09
Construction of a sequenced Clostridium perfringens-Escherichia coli shuttle plasmid. Plasmid (1992) 2.09
Clostridium perfringens toxins (type A, B, C, D, E). Pharmacol Ther (1980) 2.02
The enteric toxins of Clostridium perfringens. Rev Physiol Biochem Pharmacol (2004) 1.99
Enterotoxin plasmid from Clostridium perfringens is conjugative. Infect Immun (2001) 1.76
Electroporation-mediated transformation of lysostaphin-treated Clostridium perfringens. Gene (1989) 1.72
Identification of a transferable tetracycline resistance plasmid (pCW3) from Clostridium perfringens. Plasmid (1978) 1.68
Complete sequencing and diversity analysis of the enterotoxin-encoding plasmids in Clostridium perfringens type A non-food-borne human gastrointestinal disease isolates. J Bacteriol (2006) 1.63
Effects of alpha and theta toxins from Clostridium perfringens on human polymorphonuclear leukocytes. J Infect Dis (1987) 1.56
Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model. Infect Immun (2005) 1.49
Lambda-toxin of Clostridium perfringens activates the precursor of epsilon-toxin by releasing its N- and C-terminal peptides. Microbiol Immunol (1997) 1.48
Transferable tetracycline resistance in Clostridium perfringens strains of porcine origin. Can J Microbiol (1983) 1.48
Evidence that Tn5565, which includes the enterotoxin gene in Clostridium perfringens, can have a circular form which may be a transposition intermediate. FEMS Microbiol Lett (1999) 1.39
Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens. J Bacteriol (2006) 1.39
Worldwide distribution of the conjugative Clostridium perfringens tetracycline resistance plasmid, pCW3. Plasmid (1985) 1.38
Clostridium perfringens in animal disease: a review of current knowledge. Can Vet J (1980) 1.37
Molecular analysis of transferable tetracycline resistance plasmids from Clostridium perfringens. J Bacteriol (1985) 1.31
Virulence plasmid diversity in Clostridium perfringens type D isolates. Infect Immun (2007) 1.30
Clostridium perfringens epsilon-toxin acts on MDCK cells by forming a large membrane complex. J Bacteriol (1997) 1.26
Genetic organization and distribution of tetracycline resistance determinants in Clostridium perfringens. Antimicrob Agents Chemother (1996) 1.09
Evaluation of a new cytotoxicity assay for Clostridium perfringens type D epsilon toxin. FEMS Microbiol Lett (1994) 1.06
Diagnosis of Clostridium perfringens intestinal infections in sheep and goats. Anaerobe (2004) 1.02
Clostridium perfringens epsilon-toxin increases permeability of single perfused microvessels of rat mesentery. Infect Immun (2005) 1.01
Development of monoclonal antibodies suitable for use in antigen quantification potency tests for clostridial veterinary vaccines. Dev Biol Stand (1999) 0.94
The recA gene from Clostridium perfringens is induced by methyl methanesulphonate and contains an upstream Cheo box. Microbiology (1997) 0.83
Toxin B is essential for virulence of Clostridium difficile. Nature (2009) 5.49
Using targeted risk factor reduction to prevent falls in older in-patients: a randomised controlled trial. Age Ageing (2004) 3.27
Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens. Genome Res (2006) 2.84
Genome reduction in Leptospira borgpetersenii reflects limited transmission potential. Proc Natl Acad Sci U S A (2006) 2.71
Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol (2006) 2.65
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. PLoS One (2008) 2.35
NetB, a new toxin that is associated with avian necrotic enteritis caused by Clostridium perfringens. PLoS Pathog (2008) 2.23
Association of beta2 toxin production with Clostridium perfringens type A human gastrointestinal disease isolates carrying a plasmid enterotoxin gene. Mol Microbiol (2005) 2.06
Construction of an alpha toxin gene knockout mutant of Clostridium perfringens type A by use of a mobile group II intron. Appl Environ Microbiol (2005) 2.01
Clostridial enteric infections in pigs. J Vet Diagn Invest (2005) 1.83
Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model. Mol Microbiol (2008) 1.78
Detection of enterotoxigenic Clostridium perfringens type A isolates in American retail foods. Appl Environ Microbiol (2004) 1.66
Organization of the plasmid cpe Locus in Clostridium perfringens type A isolates. Infect Immun (2002) 1.63
Complete sequencing and diversity analysis of the enterotoxin-encoding plasmids in Clostridium perfringens type A non-food-borne human gastrointestinal disease isolates. J Bacteriol (2006) 1.63
Alpha-toxin of Clostridium perfringens is not an essential virulence factor in necrotic enteritis in chickens. Infect Immun (2006) 1.62
Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression. J Bacteriol (2002) 1.53
Revised nomenclature for transposable genetic elements. Plasmid (2008) 1.50
Epsilon-toxin is required for most Clostridium perfringens type D vegetative culture supernatants to cause lethality in the mouse intravenous injection model. Infect Immun (2005) 1.49
Dissecting the contributions of Clostridium perfringens type C toxins to lethality in the mouse intravenous injection model. Infect Immun (2006) 1.49
Multiplex PCR genotyping assay that distinguishes between isolates of Clostridium perfringens type A carrying a chromosomal enterotoxin gene (cpe) locus, a plasmid cpe locus with an IS1470-like sequence, or a plasmid cpe locus with an IS1151 sequence. J Clin Microbiol (2004) 1.40
Identification, distribution, and expression of novel genes in 10 clinical isolates of nontypeable Haemophilus influenzae. Infect Immun (2005) 1.39
Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens. Trends Microbiol (2008) 1.39
Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens. J Bacteriol (2006) 1.39
Contact with enterocyte-like Caco-2 cells induces rapid upregulation of toxin production by Clostridium perfringens type C isolates. Cell Microbiol (2009) 1.38
Study of feline injection site sarcomas. Vet Rec (2006) 1.38
Further comparison of temperature effects on growth and survival of Clostridium perfringens type A isolates carrying a chromosomal or plasmid-borne enterotoxin gene. Appl Environ Microbiol (2006) 1.38
The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives. Gut Microbes (2010) 1.37
Use of an EZ-Tn5-based random mutagenesis system to identify a novel toxin regulatory locus in Clostridium perfringens strain 13. PLoS One (2009) 1.34
Genotyping and phenotyping of beta2-toxigenic Clostridium perfringens fecal isolates associated with gastrointestinal diseases in piglets. J Clin Microbiol (2003) 1.32
The alpha-toxin of Clostridium septicum is essential for virulence. Mol Microbiol (2005) 1.32
Structure of the claudin-binding domain of Clostridium perfringens enterotoxin. J Biol Chem (2007) 1.32
Effects of Clostridium perfringens beta-toxin on the rabbit small intestine and colon. Infect Immun (2008) 1.32
Development of a duplex PCR genotyping assay for distinguishing Clostridium perfringens type A isolates carrying chromosomal enterotoxin (cpe) genes from those carrying plasmid-borne enterotoxin (cpe) genes. J Clin Microbiol (2003) 1.31
Virulence plasmid diversity in Clostridium perfringens type D isolates. Infect Immun (2007) 1.30
Binary toxin production in Clostridium difficile is regulated by CdtR, a LytTR family response regulator. J Bacteriol (2007) 1.29
Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol (2005) 1.28
The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile. PLoS Pathog (2011) 1.28
A novel small acid soluble protein variant is important for spore resistance of most Clostridium perfringens food poisoning isolates. PLoS Pathog (2008) 1.27
Genome sequence and identification of candidate vaccine antigens from the animal pathogen Dichelobacter nodosus. Nat Biotechnol (2007) 1.25
Comparison of virulence plasmids among Clostridium perfringens type E isolates. Infect Immun (2007) 1.24
The Agr-like quorum-sensing system regulates sporulation and production of enterotoxin and beta2 toxin by Clostridium perfringens type A non-food-borne human gastrointestinal disease strain F5603. Infect Immun (2011) 1.23
Identification of a prepore large-complex stage in the mechanism of action of Clostridium perfringens enterotoxin. Infect Immun (2007) 1.23
The VirSR two-component signal transduction system regulates NetB toxin production in Clostridium perfringens. Infect Immun (2010) 1.20
Extensive genomic plasticity in Pseudomonas aeruginosa revealed by identification and distribution studies of novel genes among clinical isolates. Infect Immun (2006) 1.20
TcpA, an FtsK/SpoIIIE homolog, is essential for transfer of the conjugative plasmid pCW3 in Clostridium perfringens. J Bacteriol (2007) 1.19
Comparative effects of osmotic, sodium nitrite-induced, and pH-induced stress on growth and survival of Clostridium perfringens type A isolates carrying chromosomal or plasmid-borne enterotoxin genes. Appl Environ Microbiol (2006) 1.18
Compositional and stoichiometric analysis of Clostridium perfringens enterotoxin complexes in Caco-2 cells and claudin 4 fibroblast transfectants. Cell Microbiol (2007) 1.17
Genetic characterization of type A enterotoxigenic Clostridium perfringens strains. PLoS One (2009) 1.16
Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model. Infect Immun (2007) 1.15
Prevalence of enterotoxigenic Clostridium perfringens Isolates in Pittsburgh (Pennsylvania) area soils and home kitchens. Appl Environ Microbiol (2007) 1.15
Death pathways activated in CaCo-2 cells by Clostridium perfringens enterotoxin. Infect Immun (2003) 1.14
Characterization of virulence plasmid diversity among Clostridium perfringens type B isolates. Infect Immun (2009) 1.14
The role of toxin A and toxin B in the virulence of Clostridium difficile. Trends Microbiol (2011) 1.14
Clostridium perfringens toxin genotypes in the feces of healthy North Americans. Anaerobe (2008) 1.12
The spatial organization of the VirR boxes is critical for VirR-mediated expression of the perfringolysin O gene, pfoA, from Clostridium perfringens. J Bacteriol (2004) 1.11
Sequencing and diversity analyses reveal extensive similarities between some epsilon-toxin-encoding plasmids and the pCPF5603 Clostridium perfringens enterotoxin plasmid. J Bacteriol (2008) 1.11
The importance of calcium influx, calpain and calmodulin for the activation of CaCo-2 cell death pathways by Clostridium perfringens enterotoxin. Cell Microbiol (2005) 1.11
The subtilisin-like protease AprV2 is required for virulence and uses a novel disulphide-tethered exosite to bind substrates. PLoS Pathog (2010) 1.10
Evaluating the involvement of alternative sigma factors SigF and SigG in Clostridium perfringens sporulation and enterotoxin synthesis. Infect Immun (2010) 1.10
Development and application of new mouse models to study the pathogenesis of Clostridium perfringens type C Enterotoxemias. Infect Immun (2009) 1.10
Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. PLoS Pathog (2009) 1.09
The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria. Mol Microbiol (2011) 1.07
Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum. PLoS Pathog (2008) 1.07
Toxin plasmids of Clostridium perfringens. Microbiol Mol Biol Rev (2013) 1.07
The FxRxHrS motif: a conserved region essential for DNA binding of the VirR response regulator from Clostridium perfringens. J Mol Biol (2002) 1.07