Published in Phytochemistry on September 23, 2012
To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism. Annu Rev Plant Biol (2014) 1.28
Gene discovery of modular diterpene metabolism in nonmodel systems. Plant Physiol (2013) 1.26
The application of synthetic biology to elucidation of plant mono-, sesqui-, and diterpenoid metabolism. Mol Plant (2014) 1.03
Heterologous expression and transcript analysis of gibberellin biosynthetic genes of grasses reveals novel functionality in the GA3ox family. BMC Plant Biol (2015) 0.98
Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals. Phytochemistry (2012) 0.97
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. Biochem J (2013) 0.91
Efficient heterocyclisation by (di)terpene synthases. Chem Commun (Camb) (2015) 0.89
Andrographis paniculata transcriptome provides molecular insights into tissue-specific accumulation of medicinal diterpenes. BMC Genomics (2015) 0.82
Product Rearrangement from Altering a Single Residue in the Rice syn-Copalyl Diphosphate Synthase. Org Lett (2016) 0.79
Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha. Plant Cell (2016) 0.77
Transcripts of two ent-copalyl diphosphate synthase genes differentially localize in rice plants according to their distinct biological roles. J Exp Bot (2014) 0.77
Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis. Metab Eng (2016) 0.76
The map-based sequence of the rice genome. Nature (2005) 24.17
Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res (2008) 19.09
The B73 maize genome: complexity, diversity, and dynamics. Science (2009) 18.73
Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science (2003) 8.65
The Arabidopsis GA1 locus encodes the cyclase ent-kaurene synthetase A of gibberellin biosynthesis. Plant Cell (1994) 6.50
Cloning and characterization of the maize An1 gene. Plant Cell (1995) 4.25
An overview of gibberellin metabolism enzyme genes and their related mutants in rice. Plant Physiol (2004) 3.32
Two Classes of Plant Antibiotics: Phytoalexins versus "Phytoanticipins" Plant Cell (1994) 2.16
A modular approach for facile biosynthesis of labdane-related diterpenes. J Am Chem Soc (2007) 2.13
Two rings in them all: the labdane-related diterpenoids. Nat Prod Rep (2010) 2.07
Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites. J Am Chem Soc (2001) 2.07
Rice contains two disparate ent-copalyl diphosphate synthases with distinct metabolic functions. Plant Physiol (2004) 1.88
Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products. Plant J (2004) 1.85
The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A. Plant J (1997) 1.82
Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants. Phytochemistry (2006) 1.81
Gibberellin biosynthesis in bacteria: separate ent-copalyl diphosphate and ent-kaurene synthases in Bradyrhizobium japonicum. FEBS Lett (2008) 1.73
Regulation of gibberellin biosynthesis genes during flower and early fruit development of tomato. Plant J (1999) 1.67
A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org Lett (2009) 1.65
Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis. Plant J (2004) 1.64
Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism. Plant Physiol (2007) 1.37
Identity, regulation, and activity of inducible diterpenoid phytoalexins in maize. Proc Natl Acad Sci U S A (2011) 1.33
Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase. Nat Chem Biol (2011) 1.33
Recent advances regarding diterpene cyclase genes in higher plants and fungi. Biosci Biotechnol Biochem (2008) 1.27
Diterpene synthesis in Stevia rebaudiana: recruitment and up-regulation of key enzymes from the gibberellin biosynthetic pathway. Plant J (1999) 1.27
The maize An2 gene is induced by Fusarium attack and encodes an ent-copalyl diphosphate synthase. Plant Mol Biol (2005) 1.26
Isolation of gibberellin metabolic pathway genes from barley and comparative mapping in barley, wheat and rice. Theor Appl Genet (2004) 1.04
The first step of gibberellin biosynthesis in pumpkin is catalyzed by at least two copalyl diphosphate synthases encoded by differentially regulated genes. Plant Physiol (1998) 0.99
Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals. Phytochemistry (2012) 0.97
Germination of photoblastic lettuce seeds is regulated via the control of endogenous physiologically active gibberellin content, rather than of gibberellin responsiveness. J Exp Bot (2008) 0.95
A single residue switch for Mg(2+)-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism. J Biol Chem (2010) 0.90
Cloning and characterization of cDNAs encoding ent-copalyl diphosphate synthases in wheat: insight into the evolution of rice phytoalexin biosynthetic genes. Biosci Biotechnol Biochem (2009) 0.89
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Semidwarf (sd-1), "green revolution" rice, contains a defective gibberellin 20-oxidase gene. Proc Natl Acad Sci U S A (2002) 3.51
A modular approach for facile biosynthesis of labdane-related diterpenes. J Am Chem Soc (2007) 2.13
Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis. Plant Physiol (2004) 2.06
A rice semi-dwarf gene, Tan-Ginbozu (D35), encodes the gibberellin biosynthesis enzyme, ent-kaurene oxidase. Plant Mol Biol (2004) 2.00
Identification of a biosynthetic gene cluster in rice for momilactones. J Biol Chem (2007) 1.96
Rice contains two disparate ent-copalyl diphosphate synthases with distinct metabolic functions. Plant Physiol (2004) 1.88
Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products. Plant J (2004) 1.85
Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. Appl Microbiol Biotechnol (2009) 1.80
Functional characterization of the rice kaurene synthase-like gene family. Phytochemistry (2006) 1.79
Gibberellin biosynthesis in bacteria: separate ent-copalyl diphosphate and ent-kaurene synthases in Bradyrhizobium japonicum. FEBS Lett (2008) 1.73
CYP76M7 is an ent-cassadiene C11alpha-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice. Plant Cell (2009) 1.73
Behavioral oscillations in attention: rhythmic α pulses mediated through θ band. J Neurosci (2014) 1.69
A functional genomics approach to tanshinone biosynthesis provides stereochemical insights. Org Lett (2009) 1.65
Following evolution's lead to a single residue switch for diterpene synthase product outcome. Proc Natl Acad Sci U S A (2007) 1.64
Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis. Plant J (2004) 1.64
Tissue-specific localization of an abscisic acid biosynthetic enzyme, AAO3, in Arabidopsis. Plant Physiol (2004) 1.60
Drought induction of Arabidopsis 9-cis-epoxycarotenoid dioxygenase occurs in vascular parenchyma cells. Plant Physiol (2008) 1.52
CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts. Proc Natl Acad Sci U S A (2013) 1.44
Diterpene cyclases and the nature of the isoprene fold. Proteins (2010) 1.41
CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice. Plant J (2010) 1.39
Probing the role of the DXDD motif in Class II diterpene cyclases. Chembiochem (2007) 1.39
Terpenoid synthase structures: a so far incomplete view of complex catalysis. Nat Prod Rep (2012) 1.39
Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism. Plant Physiol (2007) 1.37
Increasing complexity of a diterpene synthase reaction with a single residue switch. J Am Chem Soc (2008) 1.36
A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase. J Am Chem Soc (2007) 1.34
Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase. Nat Chem Biol (2011) 1.33
Molecular characterization of Rht-1 dwarfing genes in hexaploid wheat. Plant Physiol (2011) 1.29
Genetic evidence for natural product-mediated plant-plant allelopathy in rice (Oryza sativa). New Phytol (2011) 1.28
To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism. Annu Rev Plant Biol (2014) 1.28
Characterization of a rice gene family encoding type-A diterpene cyclases. Biosci Biotechnol Biochem (2006) 1.26
Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster. J Biol Chem (2012) 1.26
16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: potent mechanism-based inhibitors of recombinant ent-kaurene synthase from Arabidopsis thaliana. J Am Chem Soc (2007) 1.23
Manipulation of plant innate immunity and gibberellin as factor of compatibility in the mutualistic association of barley roots with Piriformospora indica. Plant J (2009) 1.23
A cold-regulated nucleic acid-binding protein of winter wheat shares a domain with bacterial cold shock proteins. J Biol Chem (2002) 1.22
Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates. J Am Chem Soc (2002) 1.19
Auxin from the developing inflorescence is required for the biosynthesis of active gibberellins in barley stems. Plant Physiol (2004) 1.18
Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis. J Am Chem Soc (2009) 1.18
Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7. FEBS Lett (2011) 1.17
An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase. Arch Biochem Biophys (2005) 1.16
Diterpene cyclases responsible for the biosynthesis of phytoalexins, momilactones A, B, and oryzalexins A-F in rice. Biosci Biotechnol Biochem (2004) 1.14
CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism. Plant Physiol (2012) 1.14
Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants. Phytochemistry (2009) 1.14
Characterization and inhibition of a class II diterpene cyclase from Mycobacterium tuberculosis: implications for tuberculosis. J Biol Chem (2009) 1.13
Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi. Proc Natl Acad Sci U S A (2007) 1.12
Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry. J Am Chem Soc (2012) 1.11
Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis. J Biol Chem (2012) 1.09
Inhibition of tiller bud outgrowth in the tin mutant of wheat is associated with precocious internode development. Plant Physiol (2012) 1.09
Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza. BMC Genomics (2014) 1.08
Regulation of flowering in the long-day grass Lolium temulentum by gibberellins and the FLOWERING LOCUS T gene. Plant Physiol (2006) 1.07
Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis. Biochem J (2010) 1.06
Isolation of gibberellin metabolic pathway genes from barley and comparative mapping in barley, wheat and rice. Theor Appl Genet (2004) 1.04
Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice. FEBS Lett (2004) 1.04
Distribution of photoperiod-insensitive alleles Ppd-B1a and Ppd-D1a and their effect on heading time in Japanese wheat cultivars. Breed Sci (2011) 1.03
Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae. Org Biomol Chem (2013) 1.02
Phytochrome- and gibberellin-mediated regulation of abscisic acid metabolism during germination of photoblastic lettuce seeds. Plant Physiol (2008) 1.01
Electrostatic effects on (di)terpene synthase product outcome. Chem Commun (Camb) (2011) 1.00
Monoterpene biosynthesis pathway construction in Escherichia coli. Phytochemistry (2003) 1.00
A novel labda-7,13e-dien-15-ol-producing bifunctional diterpene synthase from Selaginella moellendorffii. Chembiochem (2011) 1.00
Learning new color names produces rapid increase in gray matter in the intact adult human cortex. Proc Natl Acad Sci U S A (2011) 0.99
Knowledge, attitudes, and behaviour regarding breast cancer screening among women from different socio-economic regions in southwest China: a cross-sectional study. Asian Pac J Cancer Prev (2011) 0.99
Combined use of decellularized allogeneic artery conduits with autologous transdifferentiated adipose-derived stem cells for facial nerve regeneration in rats. Biomaterials (2011) 0.98
Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals. Biochem J (2011) 0.98
Synthesis of (+/-)-nosyberkol (isotuberculosinol, revised structure of edaxadiene) and (+/-)-tuberculosinol. Org Lett (2010) 0.97
Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals. Phytochemistry (2012) 0.97
Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins. Plant J (2014) 0.96
Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali. Biosci Biotechnol Biochem (2008) 0.96
Domain loss has independently occurred multiple times in plant terpene synthase evolution. Plant J (2011) 0.96
Isolation and characterization of a marine magnetotactic spirillum axenic culture QH-2 from an intertidal zone of the China Sea. Res Microbiol (2010) 0.96
Human visual cortex responds to invisible chromatic flicker. Nat Neurosci (2007) 0.95
A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase. Org Lett (2012) 0.95
Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia. J Bacteriol (2013) 0.95
Germination of photoblastic lettuce seeds is regulated via the control of endogenous physiologically active gibberellin content, rather than of gibberellin responsiveness. J Exp Bot (2008) 0.95
Novel product chemistry from mechanistic analysis of ent-copalyl diphosphate synthases from plant hormone biosynthesis. Angew Chem Int Ed Engl (2014) 0.95
CsAGP1, a gibberellin-responsive gene from cucumber hypocotyls, encodes a classical arabinogalactan protein and is involved in stem elongation. Plant Physiol (2003) 0.94
Emission of ent-kaurene, a diterpenoid hydrocarbon precursor for gibberellins, into the headspace from plants. Plant Cell Physiol (2004) 0.93
Neural response phase tracks how listeners learn new acoustic representations. Curr Biol (2013) 0.92
Cloning of a gene cluster responsible for the biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase alpha. Biosci Biotechnol Biochem (2004) 0.92
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. Biochem J (2013) 0.91