PubRank

Bruce A J Ponder

Author PubWeight™ 200.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007 29.23
2 Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 2008 9.64
3 Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 2002 8.89
4 A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 2007 7.35
5 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet 2009 7.30
6 Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008 6.22
7 Multiple loci with different cancer specificities within the 8q24 gene desert. J Natl Cancer Inst 2008 5.82
8 A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet 2009 4.38
9 Risk factors for the incidence of breast cancer: do they affect survival from the disease? J Clin Oncol 2008 3.73
10 Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003 3.70
11 Association studies for finding cancer-susceptibility genetic variants. Nat Rev Cancer 2004 3.64
12 Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst 2004 3.53
13 Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer. PLoS Biol 2008 3.49
14 Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012 3.20
15 Association of a common variant of the CASP8 gene with reduced risk of breast cancer. J Natl Cancer Inst 2004 2.66
16 FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. Hum Mol Genet 2009 2.62
17 Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. Am J Hum Genet 2002 2.57
18 Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer 2011 2.42
19 Telomere length in prospective and retrospective cancer case-control studies. Cancer Res 2010 2.30
20 Association between common variation in 120 candidate genes and breast cancer risk. PLoS Genet 2007 2.27
21 Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013 2.24
22 A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer. Cancer Res 2003 2.21
23 Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer. Hum Mol Genet 2005 2.05
24 Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum Mol Genet 2002 2.04
25 Effect of germ-line genetic variation on breast cancer survival in a population-based study. Cancer Res 2002 1.95
26 Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res 2007 1.92
27 Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers. Int J Cancer 2011 1.81
28 BRCA1 and BRCA2 mutations in a population-based study of male breast cancer. Breast Cancer Res 2001 1.66
29 Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. Mol Cancer 2010 1.64
30 IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer. Hum Mol Genet 2005 1.62
31 A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression. PLoS Genet 2011 1.60
32 Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet 2009 1.58
33 Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci 2011 1.57
34 Polymorphisms in DNA repair genes and epithelial ovarian cancer risk. Int J Cancer 2005 1.44
35 Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. Hum Mol Genet 2009 1.42
36 No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk. Cancer Epidemiol Biomarkers Prev 2010 1.40
37 Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet 2013 1.39
38 Fine scale mapping of the breast cancer 16q12 locus. Hum Mol Genet 2010 1.39
39 Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res 2012 1.37
40 RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. Neoplasia 2012 1.36
41 Common variants in mismatch repair genes and risk of invasive ovarian cancer. Carcinogenesis 2006 1.35
42 Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer. Hum Mutat 2007 1.33
43 The genetics of ovarian cancer. Best Pract Res Clin Obstet Gynaecol 2002 1.32
44 Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun 2012 1.27
45 Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis 2006 1.24
46 Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proc Natl Acad Sci U S A 2002 1.23
47 Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk. Breast Cancer Res 2007 1.22
48 Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res 2010 1.22
49 Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Cancer Res 2006 1.21
50 The effects of common genetic variants in oncogenes on ovarian cancer survival. Clin Cancer Res 2008 1.21
51 STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev 2004 1.18
52 Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast. Breast Cancer Res 2009 1.16
53 Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer. Cancer Epidemiol Biomarkers Prev 2009 1.15
54 Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Hum Mol Genet 2010 1.15
55 Master regulators of FGFR2 signalling and breast cancer risk. Nat Commun 2013 1.12
56 Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry. Int J Gynecol Pathol 2004 1.12
57 RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B. Cancer Res 2006 1.12
58 Polymorphisms in the initiators of RET (rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 2005 1.11
59 Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population. Carcinogenesis 2008 1.11
60 The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene. Int J Cancer 2011 1.09
61 Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer. PLoS One 2007 1.08
62 Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression. Cancer Epidemiol Biomarkers Prev 2006 1.06
63 Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer. Mol Cancer 2011 1.05
64 BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk. Int J Cancer 2003 1.05
65 Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2008 1.05
66 Polymorphisms in RET and its coreceptors and ligands as genetic modifiers of multiple endocrine neoplasia type 2A. Cancer Res 2006 1.04
67 Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. J Natl Cancer Inst 2004 1.03
68 Association of the progesterone receptor gene with breast cancer risk: a single-nucleotide polymorphism tagging approach. Cancer Epidemiol Biomarkers Prev 2006 1.03
69 The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6. Cancer Prev Res (Phila) 2011 1.02
70 Common variants in RB1 gene and risk of invasive ovarian cancer. Cancer Res 2006 1.01
71 Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women. Cancer Epidemiol Biomarkers Prev 2008 1.01
72 The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis. Genes Chromosomes Cancer 2012 1.00
73 Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer. Cancer Res 2008 1.00
74 Introducing a new section to Breast Cancer Research: endocrinology and hormone therapy. Breast Cancer Res 2003 0.98
75 The Ret(C620R) mutation affects renal and enteric development in a mouse model of Hirschsprung's disease. Am J Pathol 2006 0.94
76 TOX3 mutations in breast cancer. PLoS One 2013 0.93
77 Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model. Cancer Res 2003 0.92
78 The reliable identification of disease-gene associations. Cancer Epidemiol Biomarkers Prev 2005 0.90
79 BRCA1 and BRCA2 mutations in Russian familial breast cancer. Hum Mutat 2002 0.89
80 BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases. Cancer Res 2003 0.88
81 Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers. Breast Cancer Res 2012 0.88
82 Differential gene expression in the murine gastric fundus lacking interstitial cells of Cajal. BMC Gastroenterol 2003 0.85
83 Hyaluronan-mediated motility receptor gene single nucleotide polymorphisms and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2008 0.84
84 Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005 0.83
85 Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 2004 0.82
86 Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients. Eur J Cancer 2008 0.82
87 Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs. BMC Cancer 2005 0.81
88 Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online. Hum Mutat 2007 0.81
89 FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness. Carcinogenesis 2016 0.78
90 A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation. Mol Endocrinol 2006 0.78
91 Novel SRESPHP peptide mediates specific binding to primary medullary thyroid carcinoma after systemic injection. Hum Gene Ther 2005 0.77
92 Novel human, mouse and xenopus genes encoding a member of the RAS superfamily of low-molecular-weight GTP-binding proteins and its downregulation in W/WV mouse jejunum. J Gastroenterol Hepatol 2004 0.77
93 Long-term follow up of a "sporadic" unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman. Endocr Pathol 2003 0.76
94 Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal. BMC Gastroenterol 2003 0.76
95 Breast Cancer Research--the first ten years. Breast Cancer Res 2008 0.75
96 Reply: a bias in genotyping of the ERBB2 (HER2) Ile655Val variant. Carcinogenesis 2005 0.75