Published in PLoS One on October 15, 2012
Vitamin E inadequacy in humans: causes and consequences. Adv Nutr (2014) 0.97
Novel liquid chromatography-mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos. Redox Biol (2013) 0.96
Lethal Dysregulation of Energy Metabolism During Embryonic Vitamin E Deficiency. Free Radic Biol Med (2017) 0.89
Novel function of vitamin E in regulation of zebrafish (Danio rerio) brain lysophospholipids discovered using lipidomics. J Lipid Res (2015) 0.84
Interactions between α-tocopherol, polyunsaturated fatty acids, and lipoxygenases during embryogenesis. Free Radic Biol Med (2013) 0.78
Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets. Free Radic Biol Med (2017) 0.75
Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72
High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc (2008) 10.25
p53 activation by knockdown technologies. PLoS Genet (2007) 6.85
ON THE EXISTENCE OF A HITHERTO UNRECOGNIZED DIETARY FACTOR ESSENTIAL FOR REPRODUCTION. Science (1922) 3.86
Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis (2001) 3.04
Proteomics of early zebrafish embryos. BMC Dev Biol (2006) 2.36
Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in Italian families. Neurol Sci (2004) 1.92
Achieving targeted and quantifiable alteration of mRNA splicing with Morpholino oligos. Biochem Biophys Res Commun (2007) 1.56
The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein. J Mol Biol (2003) 1.54
Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E. Proc Natl Acad Sci U S A (2000) 1.41
Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency. Proc Natl Acad Sci U S A (2003) 1.31
Alpha-tocopherol transfer protein is important for the normal development of placental labyrinthine trophoblasts in mice. J Biol Chem (2000) 1.22
Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol (2010) 1.22
Turning gene function ON and OFF using sense and antisense photo-morpholinos in zebrafish. Development (2012) 1.19
Lessons from morpholino-based screening in zebrafish. Brief Funct Genomics (2011) 1.14
Zebrafish (Danio rerio) fed vitamin E-deficient diets produce embryos with increased morphologic abnormalities and mortality. J Nutr Biochem (2011) 1.08
β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos. Development (2012) 1.05
The alpha-tocopherol transfer protein. Vitam Horm (2007) 1.03
α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome. Free Radic Biol Med (2011) 0.97
Distribution and transfer pathways of antioxidant molecules inside the first trimester human gestational sac. J Clin Endocrinol Metab (2004) 0.97
Molecular determinants of heritable vitamin E deficiency. Biochemistry (2004) 0.95
Spatacsin and spastizin act in the same pathway required for proper spinal motor neuron axon outgrowth in zebrafish. Neurobiol Dis (2012) 0.95
Ataxia caused by mutations in the alpha-tocopherol transfer protein gene. J Neurol Neurosurg Psychiatry (2000) 0.92
Preparation of fluorescent tocopherols for use in protein binding and localization with the alpha-tocopherol transfer protein. Bioorg Med Chem (2006) 0.90
Human placental trophoblast cells express alpha-tocopherol transfer protein. Placenta (2003) 0.89
Zinc transporter expression in zebrafish (Danio rerio) during development. Comp Biochem Physiol C Toxicol Pharmacol (2011) 0.89
Alpha-tocopherol transfer protein is specifically localized at the implantation site of pregnant mouse uterus. Biol Reprod (2002) 0.88
The Amotl2 gene inhibits Wnt/β-catenin signaling and regulates embryonic development in zebrafish. J Biol Chem (2012) 0.87
Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placenta. Free Radic Res (2004) 0.86
The Osr1 and Osr2 genes act in the pronephric anlage downstream of retinoic acid signaling and upstream of Wnt2b to maintain pectoral fin development. Development (2011) 0.85
Biological activity of vitamin E compounds and natural materials by the resorption-gestation test, and chemical determination of the vitamin E activity in foods and feeds. J Nutr (1977) 0.84
Expression and refolding of recombinant human alpha-tocopherol transfer protein capable of specific alpha-tocopherol binding. Protein Expr Purif (2002) 0.83
Maternal dietary loads of α-tocopherol depress protein kinase C signaling and synaptic plasticity in rat postnatal developing hippocampus and promote permanent deficits in adult offspring. J Nutr Biochem (2010) 0.81
Maternal dietary loads of α-tocopherol differentially influence fear conditioning and spatial learning in adult offspring. Physiol Behav (2011) 0.79
Biopotencies in rats of several forms of alpha-tocopherol. J Nutr (1979) 0.79
Structure and function of alpha-tocopherol transfer protein: implications for vitamin E metabolism and AVED. Vitam Horm (2007) 0.78
Majority of Americans not consuming vitamin E RDA. J Nutr (2011) 0.78
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature (2012) 10.99
Vitamin E, antioxidant and nothing more. Free Radic Biol Med (2007) 3.87
Vitamins E and C are safe across a broad range of intakes. Am J Clin Nutr (2005) 2.72
Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation. Free Radic Biol Med (2005) 1.85
Regenerative growth is impacted by TCDD: gene expression analysis reveals extracellular matrix modulation. Toxicol Sci (2006) 1.74
Smoking and exposure to environmental tobacco smoke decrease some plasma antioxidants and increase gamma-tocopherol in vivo after adjustment for dietary antioxidant intakes. Am J Clin Nutr (2003) 1.74
Recommendations for control of pathogens and infectious diseases in fish research facilities. Comp Biochem Physiol C Toxicol Pharmacol (2008) 1.66
Sulfidation of silver nanoparticles: natural antidote to their toxicity. Environ Sci Technol (2013) 1.64
In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish. Carbon N Y (2007) 1.62
Evaluation of embryotoxicity using the zebrafish model. Methods Mol Biol (2011) 1.57
Subcutaneous vitamin E ameliorates liver injury in an in vivo model of steatocholestasis. Hepatology (2007) 1.53
Development and maintenance of a specific pathogen-free (SPF) zebrafish research facility for Pseudoloma neurophilia. Dis Aquat Organ (2011) 1.53
Effects of suboptimal doses of the AT1 receptor blocker, telmisartan, with the angiotensin-converting enzyme inhibitor, ramipril, on cerebral arterioles in spontaneously hypertensive rat. J Hypertens (2010) 1.49
Automated zebrafish chorion removal and single embryo placement: optimizing throughput of zebrafish developmental toxicity screens. J Lab Autom (2012) 1.46
Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements. Am J Clin Nutr (2004) 1.46
Gene expression profiling from formalin-fixed paraffin-embedded tumors of pediatric glioblastoma. Clin Cancer Res (2007) 1.44
Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish. Toxicol Appl Pharmacol (2008) 1.42
Multidimensional in vivo hazard assessment using zebrafish. Toxicol Sci (2013) 1.41
Systematic evaluation of nanomaterial toxicity: utility of standardized materials and rapid assays. ACS Nano (2011) 1.37
Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish. Neurotoxicol Teratol (2004) 1.37
How much vitamin E? ... Just enough! Am J Clin Nutr (2006) 1.35
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas. Clin Cancer Res (2011) 1.35
Unraveling tissue regeneration pathways using chemical genetics. J Biol Chem (2007) 1.35
Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol Sci (2002) 1.33
Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome. Free Radic Biol Med (2007) 1.30
Ligand specificity in the CRAL-TRIO protein family. Biochemistry (2003) 1.29
Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production. Free Radic Biol Med (2005) 1.28
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands. J Med Chem (2009) 1.28
Ethanol-dependent toxicity in zebrafish is partially attenuated by antioxidants. Neurotoxicol Teratol (2006) 1.21
Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in rats. J Nutr (2009) 1.21
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes. Anal Biochem (2006) 1.21
Does gamma-tocopherol play a role in the primary prevention of heart disease and cancer? A review. J Am Coll Nutr (2006) 1.19
Neurodevelopmental low-dose bisphenol A exposure leads to early life-stage hyperactivity and learning deficits in adult zebrafish. Toxicology (2011) 1.18
Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1. Mol Pharmacol (2005) 1.16
Differential stability of lead sulfide nanoparticles influences biological responses in embryonic zebrafish. Arch Toxicol (2010) 1.16
The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor. Mol Pharmacol (2002) 1.15
Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery. Mol Nutr Food Res (2009) 1.13
Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats. Free Radic Biol Med (2006) 1.13
Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration. J Lipid Res (2005) 1.12
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. PLoS One (2012) 1.12
Persistent adult zebrafish behavioral deficits results from acute embryonic exposure to gold nanoparticles. Comp Biochem Physiol C Toxicol Pharmacol (2011) 1.11
Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2. Drug Metab Dispos (2005) 1.11
Dietary patterns are associated with plasma F₂-isoprostanes in an observational cohort study of adults. Free Radic Biol Med (2012) 1.08
Dithiocarbamates have a common toxic effect on zebrafish body axis formation. Toxicol Appl Pharmacol (2006) 1.08
Zebrafish (Danio rerio) fed vitamin E-deficient diets produce embryos with increased morphologic abnormalities and mortality. J Nutr Biochem (2011) 1.08
Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator. Mol Pharmacol (2007) 1.07
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor. PLoS One (2010) 1.07
Antioxidant supplementation decreases lipid peroxidation biomarker F(2)-isoprostanes in plasma of smokers. Cancer Epidemiol Biomarkers Prev (2002) 1.07
Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. Nutr Cancer (2004) 1.07
Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish. FASEB J (2008) 1.07
{alpha}-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid status. Am J Clin Nutr (2005) 1.06
A history of vitamin E. Ann Nutr Metab (2012) 1.06
Nicotinic receptors mediate changes in spinal motoneuron development and axonal pathfinding in embryonic zebrafish exposed to nicotine. J Neurosci (2002) 1.06
Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis. Mol Cancer Ther (2003) 1.05
Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners. Free Radic Biol Med (2004) 1.05
Endurance exercise results in DNA damage as detected by the comet assay. Free Radic Biol Med (2004) 1.04
Intracellular trafficking of vitamin E in hepatocytes: the role of tocopherol transfer protein. J Lipid Res (2005) 1.04
Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics. J Biol Chem (2004) 1.04
MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J (2012) 1.04
Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS). Aquat Toxicol (2010) 1.04
Vitamin E. Vitam Horm (2007) 1.03
Molecular signaling networks that choreograph epimorphic fin regeneration in zebrafish - a mini-review. Gerontology (2009) 1.03
Comparative expression profiling reveals an essential role for raldh2 in epimorphic regeneration. J Biol Chem (2009) 1.02
Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Toxicol Appl Pharmacol (2013) 1.02
gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury. Free Radic Biol Med (2008) 1.02
Developmental toxicity of the dithiocarbamate pesticide sodium metam in zebrafish. Toxicol Sci (2004) 1.02
An isoform of ZBP-89 predisposes the colon to colitis. Nucleic Acids Res (2006) 1.02
The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells. PLoS One (2012) 1.01
Mechanisms of aortic and cardiac dysfunction in uremic mice with aortic calcification. Circulation (2008) 1.01
Aryl hydrocarbon receptor activation inhibits regenerative growth. Mol Pharmacol (2005) 1.00
Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology. Lipids (2008) 1.00
Vitamin E biokinetics, oxidative stress and cigarette smoking. Pathophysiology (2006) 0.99
Toxicity of chlorine to zebrafish embryos. Dis Aquat Organ (2014) 0.99
Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens (2005) 0.99
Aryl hydrocarbon receptor activation impairs extracellular matrix remodeling during zebra fish fin regeneration. Toxicol Sci (2006) 0.98
Integrating zebrafish toxicology and nanoscience for safer product development. Green Chem (2013) 0.98
Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior. Toxicol Sci (2011) 0.97
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish. J Biol Chem (2011) 0.97
Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation. Mol Cell Biol (2006) 0.97
Vitamin E inadequacy in humans: causes and consequences. Adv Nutr (2014) 0.97
Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio). J Nutr (2011) 0.96
AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration. Biochem Pharmacol (2008) 0.96
Gold nanoparticles disrupt zebrafish eye development and pigmentation. Toxicol Sci (2013) 0.96
Differential response of human ovarian cancer cells to induction of apoptosis by vitamin E Succinate and vitamin E analogue, alpha-TEA. Cancer Res (2004) 0.96
Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis. Cancer Chemother Pharmacol (2004) 0.95
Alpha-tocopherol modulates genes involved in hepatic xenobiotic pathways in mice. J Nutr Biochem (2008) 0.95
Human vitamin E requirements assessed with the use of apples fortified with deuterium-labeled alpha-tocopheryl acetate. Am J Clin Nutr (2006) 0.95
Vitamin E trafficking in neurologic health and disease. Annu Rev Nutr (2013) 0.95
Vitamin E and transfer proteins. Curr Opin Lipidol (2003) 0.95