Published in Cell Mol Immunol on October 22, 2012
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New developments in Toll-like receptor targeted therapeutics. Curr Opin Pharmacol (2012) 1.10
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TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine (2010) 0.91
Genetic modulation of TLR8 response following bacterial phagocytosis. Hum Mutat (2010) 0.88
R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes. BMC Infect Dis (2012) 0.86
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Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod. Mol Immunol (2008) 0.86
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VTX-1463, a novel TLR8 agonist for the treatment of allergic rhinitis. Expert Opin Investig Drugs (2011) 0.84
The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation. Cell Immunol (2011) 0.83
Maternal and congenital syphilis in rural Haiti. Rev Panam Salud Publica (2009) 1.44
Phagocytosis of Borrelia burgdorferi and Treponema pallidum potentiates innate immune activation and induces gamma interferon production. Infect Immun (2007) 1.42
Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta. Proc Natl Acad Sci U S A (2011) 1.36
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Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade. Proc Natl Acad Sci U S A (2011) 1.33
Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes. Infect Immun (2007) 1.31
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CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi. Proc Natl Acad Sci U S A (2012) 1.18
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TP0326, a Treponema pallidum β-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein. Mol Microbiol (2011) 1.06
CD14 signaling restrains chronic inflammation through induction of p38-MAPK/SOCS-dependent tolerance. PLoS Pathog (2009) 1.06
Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartments. PLoS Negl Trop Dis (2012) 1.05
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Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence. Infect Immun (2010) 0.98
Familial disease, the HLA-DRB1 shared epitope and anti-CCP antibodies influence time at appearance of substantial joint damage in rheumatoid arthritis. J Autoimmun (2008) 0.97
TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure. J Bacteriol (2012) 0.96
Serine lipids of Porphyromonas gingivalis are human and mouse Toll-like receptor 2 ligands. Infect Immun (2013) 0.93
Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes. J Leukoc Biol (2013) 0.91
Atovaquone and azithromycin treatment for babesiosis in an infant. Pediatr Infect Dis J (2007) 0.89
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Gestational and congenital syphilis epidemic in the Colombian Pacific Coast. Sex Transm Dis (2013) 0.80
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Streptococcus pyogenes pyomyositis. Pediatr Infect Dis J (2002) 0.78
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Anti-CCP antibodies are associated with early age at onset in patients with rheumatoid arthritis. Joint Bone Spine (2011) 0.77
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MyD88 deficiency markedly worsens tissue inflammation and bacterial clearance in mice infected with Treponema pallidum, the agent of syphilis. PLoS One (2013) 0.75
Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4. Sci Rep (2016) 0.75
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Open-label evaluation of a novel skin brightening system containing 0.01% decapeptide-12 in combination with 20% buffered glycolic acid for the treatment of mild to moderate facial melasma. J Drugs Dermatol (2013) 0.75
Corrigendum: Pregnane X Receptor Regulates Pathogen-Induced Inflammation and Host Defense against an Intracellular Bacterial Infection through Toll-like Receptor 4. Sci Rep (2017) 0.75
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