Splenic red pulp macrophages produce type I interferons as early sentinels of malaria infection but are dispensable for control.

PubWeight™: 0.94‹?›

🔗 View Article (PMC 3483282)

Published in PLoS One on October 29, 2012

Authors

Charles C Kim1, Christopher S Nelson, Emily B Wilson, Baidong Hou, Anthony L DeFranco, Joseph L DeRisi

Author Affiliations

1: Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Articles citing this

Macrophage Colony Stimulating Factor Derived from CD4+ T Cells Contributes to Control of a Blood-Borne Infection. PLoS Pathog (2016) 1.39

Differential induction of TLR3-dependent innate immune signaling by closely related parasite species. PLoS One (2014) 1.11

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity. J Clin Invest (2014) 0.96

Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality. Proc Natl Acad Sci U S A (2014) 0.91

Toll-like receptor 7 mediates early innate immune responses to malaria. Infect Immun (2013) 0.85

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure. PLoS Pathog (2015) 0.83

JUNB is a key transcriptional modulator of macrophage activation. J Immunol (2014) 0.80

Krüppel mediates the selective rebalancing of ion channel expression. Neuron (2014) 0.80

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. PLoS Pathog (2016) 0.78

Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria. PLoS Pathog (2016) 0.77

Interferons and interferon regulatory factors in malaria. Mediators Inflamm (2014) 0.77

A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection. PLoS One (2016) 0.76

CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans. PLoS Pathog (2016) 0.75

STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria. PLoS Pathog (2016) 0.75

The p60 and NamA autolysins from Listeria monocytogenes contribute to host colonization and induction of protective memory. Cell Microbiol (2014) 0.75

From the Cradle to the Grave: The Role of Macrophages in Erythropoiesis and Erythrophagocytosis. Front Immunol (2017) 0.75

Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections. Parasite Immunol (2015) 0.75

Articles cited by this

IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature (2005) 13.23

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity (2000) 10.34

Plasmacytoid dendritic cells in immunity. Nat Immunol (2004) 9.11

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification. Nucleic Acids Res (2009) 5.03

Type I interferon: friend or foe? J Exp Med (2010) 4.40

An atomic model of the interferon-beta enhanceosome. Cell (2007) 4.22

Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J Exp Med (2002) 3.86

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med (2005) 3.85

Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity (2008) 3.48

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc Natl Acad Sci U S A (2007) 3.41

Migration of dendritic cell subsets and their precursors. Annu Rev Immunol (2008) 3.04

Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses. Immunity (2007) 2.78

Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance. Immunol Rev (2010) 2.55

Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J Immunol (2004) 2.33

The importance of the spleen in malaria. Trends Parasitol (2005) 2.23

Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature (2008) 2.18

Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses. J Immunol (2010) 2.09

Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. Immunity (2008) 1.97

Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7. PLoS Pathog (2009) 1.95

Induction of an IL7-R(+)c-Kit(hi) myelolymphoid progenitor critically dependent on IFN-gamma signaling during acute malaria. Nat Immunol (2010) 1.80

CD4+ T cells and B cells are necessary for the transfer of protective immunity to Plasmodium chabaudi chabaudi. Eur J Immunol (1991) 1.65

Splenic marginal metallophilic macrophages and marginal zone macrophages are the major interferon-alpha/beta producers in mice upon intravenous challenge with herpes simplex virus. Scand J Immunol (1999) 1.52

Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes. PLoS Pathog (2009) 1.50

Gene-targeted mice lacking B cells are unable to eliminate a blood stage malaria infection. J Immunol (1996) 1.49

Visualization of IFNbeta production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo. Proc Natl Acad Sci U S A (2008) 1.44

Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria. Blood (2009) 1.40

Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog (2006) 1.40

Positive correlation between degree of parasitemia, interferon titers, and natural killer cell activity in Plasmodium falciparum-infected children. J Immunol (1981) 1.38

Roles of CD4- and CD8-bearing T lymphocytes in the immune response to the erythrocytic stages of Plasmodium chabaudi. Infect Immun (1988) 1.38

Pitting function of the spleen in malaria: ultrastructural observations. Science (1972) 1.28

Role of mononuclear phagocytes in elimination of Plasmodium chabaudi AS infection. Parasite Immunol (1989) 1.21

Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun (2007) 1.19

Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria. Int J Parasitol (2009) 1.16

The resolution of acute malaria in a definitive model of B cell deficiency, the JHD mouse. J Immunol (1994) 1.11

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection. Eur J Immunol (2011) 1.10

Impact of macrophage and dendritic cell subset elimination on antiviral immunity, viral clearance and production of type 1 interferon. Virology (2005) 1.10

A distinct peripheral blood monocyte phenotype is associated with parasite inhibitory activity in acute uncomplicated Plasmodium falciparum malaria. PLoS Pathog (2009) 1.09

Trafficking of Plasmodium chabaudi adami-infected erythrocytes within the mouse spleen. Proc Natl Acad Sci U S A (1996) 1.05

Histological changes in the spleen and liver of C57BL/6 and A/J mice during Plasmodium chabaudi AS infection. Exp Mol Pathol (1989) 1.02

Massive destruction of malaria-parasitized red blood cells despite spleen closure. Infect Immun (2005) 0.98

Splenic gammadelta T cells regulated by CD4+ T cells are required to control chronic Plasmodium chabaudi malaria in the B-cell-deficient mouse. Infect Immun (2006) 0.95

Experimental malaria infection triggers early expansion of natural killer cells. Infect Immun (2008) 0.89

Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery. J Immunol Methods (2009) 0.87

Articles by these authors

Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science (2003) 18.34

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature (2006) 12.92

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol (2003) 11.86

Retracted Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog (2006) 10.08

Assemblathon 1: a competitive assessment of de novo short read assembly methods. Genome Res (2011) 8.38

Microarray-based detection and genotyping of viral pathogens. Proc Natl Acad Sci U S A (2002) 7.27

Viral discovery and sequence recovery using DNA microarrays. PLoS Biol (2003) 5.95

Chemical genetics of Plasmodium falciparum. Nature (2010) 5.52

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray. Genome Biol (2003) 4.24

Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis (2007) 4.16

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae. PLoS Biol (2004) 4.03

Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity (2008) 3.48

Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections. Proc Natl Acad Sci U S A (2008) 2.84

Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains. Nucleic Acids Res (2006) 2.78

Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med (2014) 2.71

Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent. Virol J (2008) 2.69

The complete genome of klassevirus - a novel picornavirus in pediatric stool. Virol J (2009) 2.46

Human enterovirus 109: a novel interspecies recombinant enterovirus isolated from a case of acute pediatric respiratory illness in Nicaragua. J Virol (2010) 2.31

Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia. PLoS One (2011) 2.23

Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum. PLoS Biol (2011) 2.21

Searching for new antimalarial therapeutics amongst known drugs. Chem Biol Drug Des (2006) 2.10

De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis. Nat Biotechnol (2010) 2.05

Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle. Genome Biol (2007) 2.03

Tetracyclines specifically target the apicoplast of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother (2006) 1.95

Genome-wide diversity and selective pressure in the human rhinovirus. Virol J (2007) 1.94

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns. Genome Biol (2005) 1.93

Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors. J Biol Chem (2004) 1.85

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. Clin Infect Dis (2006) 1.84

N-terminal processing of proteins exported by malaria parasites. Mol Biochem Parasitol (2008) 1.81

Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface. Proc Natl Acad Sci U S A (2011) 1.80

The kinetochore is an enhancer of pericentric cohesin binding. PLoS Biol (2004) 1.79

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. Nat Immunol (2011) 1.77

Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nat Immunol (2006) 1.76

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity (2011) 1.70

Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray. J Clin Microbiol (2007) 1.67

Visualizing lipid raft dynamics and early signaling events during antigen receptor-mediated B-lymphocyte activation. Mol Biol Cell (2003) 1.66

NK cells and immune "memory". J Immunol (2011) 1.66

Comparative analysis of tandem repeats from hundreds of species reveals unique insights into centromere evolution. Genome Biol (2013) 1.65

Rapid DNA mapping by fluorescent single molecule detection. Nucleic Acids Res (2006) 1.63

Virus identification in unknown tropical febrile illness cases using deep sequencing. PLoS Negl Trop Dis (2012) 1.52

Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.52

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. Nucleic Acids Res (2011) 1.48

Discovery of a novel polyomavirus in acute diarrheal samples from children. PLoS One (2012) 1.48

B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity (2012) 1.47

Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells. Nat Immunol (2012) 1.41

Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors. Proc Natl Acad Sci U S A (2010) 1.37

HMMSplicer: a tool for efficient and sensitive discovery of known and novel splice junctions in RNA-Seq data. PLoS One (2010) 1.36

The long march: a sample preparation technique that enhances contig length and coverage by high-throughput short-read sequencing. PLoS One (2008) 1.31

Lipid rafts and B cell signaling. Semin Cell Dev Biol (2007) 1.29

Mapping of the functional interconnections between thalamic reticular neurons using photostimulation. J Neurophysiol (2006) 1.29

The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 1.27

Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2005) 1.25

Parallel synthesis and antimalarial screening of a 4-aminoquinoline library. J Comb Chem (2004) 1.23

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance. J Immunol (2009) 1.21

Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4. Virol J (2009) 1.19

Using a pan-viral microarray assay (Virochip) to screen clinical samples for viral pathogens. J Vis Exp (2011) 1.17

Mnd1p: an evolutionarily conserved protein required for meiotic recombination. Proc Natl Acad Sci U S A (2002) 1.17

Structure of the transcriptional network controlling white-opaque switching in Candida albicans. Mol Microbiol (2013) 1.14

TLR signaling in B-cell development and activation. Cell Mol Immunol (2012) 1.12

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice. J Immunol (2013) 1.09

Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation. Proc Natl Acad Sci U S A (2013) 1.03

Making and breaking tolerance. Curr Opin Immunol (2002) 1.03

Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains. Proc Natl Acad Sci U S A (2013) 1.03

Contribution of Toll-like receptor signaling to germinal center antibody responses. Immunol Rev (2012) 1.02

Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation. Genome Biol (2014) 1.02

B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice. Proc Natl Acad Sci U S A (2011) 1.01

Past, present, and future of arenavirus taxonomy. Arch Virol (2015) 1.00

B cell-specific loss of Lyn kinase leads to autoimmunity. J Immunol (2013) 1.00

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. J Exp Med (2014) 0.98

Development of a new generation of 4-aminoquinoline antimalarial compounds using predictive pharmacokinetic and toxicology models. J Med Chem (2010) 0.98

Identification and manipulation of the molecular determinants influencing poliovirus recombination. PLoS Pathog (2013) 0.98

DNA microarrays for malaria. Trends Parasitol (2002) 0.97

Serological evidence of human klassevirus infection. Clin Vaccine Immunol (2010) 0.97

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum. J Med Chem (2006) 0.96

Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. Blood (2011) 0.96

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum. Bioorg Med Chem (2005) 0.95

Improved methods for magnetic purification of malaria parasites and haemozoin. Malar J (2010) 0.95

Pernicious plans revealed: Plasmodium falciparum genome wide expression analysis. Curr Opin Microbiol (2004) 0.94

Draft Genome Sequences of Marine RNA Viruses SF-1, SF-2, and SF-3 Recovered from San Francisco Wastewater. Genome Announc (2015) 0.92

Draft Genome Sequences of Leviviridae RNA Phages EC and MB Recovered from San Francisco Wastewater. Genome Announc (2015) 0.92

Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis. Virol J (2012) 0.91

Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells. J Immunol (2008) 0.91

Plate-based transfection and culturing technique for genetic manipulation of Plasmodium falciparum. Malar J (2012) 0.91

Maximal adjuvant activity of nasally delivered IL-1α requires adjuvant-responsive CD11c(+) cells and does not correlate with adjuvant-induced in vivo cytokine production. J Immunol (2012) 0.89

Experimental malaria infection triggers early expansion of natural killer cells. Infect Immun (2008) 0.89

Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc Natl Acad Sci U S A (2012) 0.89

ReCombine: a suite of programs for detection and analysis of meiotic recombination in whole-genome datasets. PLoS One (2011) 0.85

ACBD3 interaction with TBC1 domain 22 protein is differentially affected by enteroviral and kobuviral 3A protein binding. MBio (2013) 0.84

Optimization of propafenone analogues as antimalarial leads. J Med Chem (2011) 0.82

Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor. J Am Chem Soc (2012) 0.82

Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells. Eur J Immunol (2011) 0.81

Signaling mutations and autoimmunity. Curr Dir Autoimmun (2003) 0.81

Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity. J Med Chem (2011) 0.81