Published in Annu Rev Neurosci on January 01, 1979
Flow of information in the light-triggered cyclic nucleotide cascade of vision. Proc Natl Acad Sci U S A (1981) 4.87
Spatial spread of activation and background desensitization in toad rod outer segments. J Physiol (1981) 4.53
The ionic selectivity and calcium dependence of the light-sensitive pathway in toad rods. J Physiol (1985) 3.42
Receptor structure in the bacterial sensing system. Proc Natl Acad Sci U S A (1980) 2.95
Effect of ions on retinal rods from Bufo marinus. J Physiol (1984) 2.38
Patch-clamp recordings of the light-sensitive dark noise in retinal rods from the lizard and frog. J Physiol (1985) 2.26
Incorporation of calcium buffers into salamander retinal rods: a rejection of the calcium hypothesis of phototransduction. J Physiol (1986) 1.79
Control of the light-regulated current in rod photoreceptors by cyclic GMP, calcium, and l-cis-diltiazem. Proc Natl Acad Sci U S A (1986) 1.73
Surfaces of rod photoreceptor disk membranes: integral membrane components. J Cell Biol (1982) 1.67
Control of the generator current in solitary rods of the Ambystoma tigrinum retina. J Physiol (1984) 1.47
Light-induced calcium release by intact retinal rods. Proc Natl Acad Sci U S A (1980) 1.45
The effects of phosphodiesterase inhibitors and lanthanum ions on the light-sensitive current of toad retinal rods. J Physiol (1986) 1.45
Involvement of cyclic GMP in intracellular signaling in the chemotactic response of Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.29
The effect of phosphodiesterase inhibitors on the electrical activity of toad rods. J Physiol (1983) 1.14
Influence of light and calcium on guanosine 5'-triphosphate in isolated frog rod outer segments. J Gen Physiol (1979) 1.06
Calcium and cyclic GMP regulation of light-sensitive protein phosphorylation in frog photoreceptor membranes. J Gen Physiol (1982) 1.03
Antagonism between steady light and phosphodiesterase inhibitors on the kinetics of rod photoresponses. Proc Natl Acad Sci U S A (1982) 0.99
Internal dialysis of Limulus ventral photoreceptors. Proc Natl Acad Sci U S A (1982) 0.98
Preparation and characterization of monoclonal antibodies to several frog rod outer segment proteins. J Gen Physiol (1984) 0.97
Influence of calcium on guanosine 3',5'-cyclic monophosphate levels in frog rod outer segments. J Gen Physiol (1981) 0.97
Calcium effects on frog retinal cyclic guanosine 3', 5'-monophosphate levels and their light-initiated rate of decay. J Gen Physiol (1980) 0.96
Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic adenosine 3','5-monophosphate. J Gen Physiol (1982) 0.94
Light adaption of the cyclic GMP phosphodiesterase of frog photoreceptor membranes mediated by ATP and calcium ions. J Gen Physiol (1981) 0.93
Effects of cyclic adenosine 3',5'-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. J Gen Physiol (1982) 0.89
Calcium-induced inactivation of alamethicin in asymmetric lipid bilayers. J Gen Physiol (1982) 0.88
Regulation of retinal transducin by C-terminal peptides of rhodopsin. Biochem J (1985) 0.81
Effects of calcium and guanosine-3',5'-cyclic-monophosphoric acid on receptor potentials of toad rods. J Physiol (1983) 0.79
Effect of pH on the formation and decay of the metarhodopsins of the frog. J Physiol (1981) 0.77
Molecular motion in spin-labeled phospholipids and membranes. J Am Chem Soc (1971) 7.23
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science (1996) 6.50
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics. Biochemistry (1996) 5.52
Spin-label studies of the excitable membranes of nerve and muscle. Proc Natl Acad Sci U S A (1968) 4.58
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proc Natl Acad Sci U S A (1994) 4.27
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants. Science (1990) 4.07
The membrane dipole potential in a total membrane potential model. Applications to hydrophobic ion interactions with membranes. Biophys J (1986) 3.51
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure. Biochemistry (2000) 3.46
Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure. Biochemistry (2001) 3.45
Electrostatic interactions in membranes and proteins. Annu Rev Biophys Biophys Chem (1986) 3.28
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines. Biochemistry (1989) 3.25
Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: experimental strategies and practical limitations. Biochemistry (2001) 2.89
Preparation and properties of phospholipid bilayers containing rhodopsin. Proc Natl Acad Sci U S A (1972) 2.42
Orientation and motion of amphiphilic spin labels in membranes. Proc Natl Acad Sci U S A (1969) 2.29
Molecular characterization of helix-loop-helix peptides. Science (1992) 2.26
Amplitude, kinetics, and reversibility of a light-induced decrease in guanosine 3',5'-cyclic monophosphate in frog photoreceptor membranes. J Gen Physiol (1979) 2.15
Spin labeled cysteines as sensors for protein-lipid interaction and conformation in rhodopsin. Photochem Photobiol (1992) 1.96
Motion of fatty acid spin labels in the plasma membrane of mycoplasma. Biochim Biophys Acta (1970) 1.91
Lipid requirements for Rhodopsin regenerability. Biochemistry (1973) 1.89
Temperature- and light-dependent structural changes in rhodopsin-lipid membranes. Exp Eye Res (1973) 1.89
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. Biochemistry (1996) 1.88
The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements. Neuron (2000) 1.83
Stability of "salt bridges" in membrane proteins. Proc Natl Acad Sci U S A (1984) 1.79
Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling. Biochemistry (1997) 1.76
Colicin E1 binding to membranes: time-resolved studies of spin-labeled mutants. Science (1993) 1.73
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. Science (1994) 1.70
Control of the cyclic GMP phosphodiesterase of frog photoreceptor membranes. J Gen Physiol (1980) 1.68
Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP. Nature (1992) 1.66
Site-specific incorporation of biophysical probes into proteins. Proc Natl Acad Sci U S A (1994) 1.66
Estimation of membrane surface potential and charge density from the phase equilibrium of a paramagnetic amphiphile. Biochemistry (1976) 1.65
Inhibition of rhodopsin kinase by recoverin. Further evidence for a negative feedback system in phototransduction. J Biol Chem (1995) 1.65
Hydrophobic ion interactions with membranes. Thermodynamic analysis of tetraphenylphosphonium binding to vesicles. Biophys J (1986) 1.64
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study. Science (1996) 1.64
Tear lipocalins bind a broad array of lipid ligands. Curr Eye Res (1995) 1.63
Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study. Biochemistry (2001) 1.62
The intrinsic pKa values for phosphatidylserine and phosphatidylethanolamine in phosphatidylcholine host bilayers. Biophys J (1986) 1.58
Conformation of spin-labeled melittin at membrane surfaces investigated by pulse saturation recovery and continuous wave power saturation electron paramagnetic resonance. Biophys J (1989) 1.57
EPR determination of membrane potentials. Annu Rev Biophys Bioeng (1981) 1.56
Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment. Biochemistry (1999) 1.56
Calculation of electron paramagnetic resonance spectra from Brownian dynamics trajectories: application to nitroxide side chains in proteins. Biophys J (1996) 1.55
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. Biochemistry (1993) 1.55
Protein complement of rod outer segments of frog retina. Biochemistry (1986) 1.54
A multifrequency electron spin resonance study of T4 lysozyme dynamics. Biophys J (1999) 1.54
Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation. Proteins (1989) 1.54
Motion of spin-labeled side chains in T4 lysozyme: effect of side chain structure. Biochemistry (1999) 1.51
Interaction of the isolated transmembrane domain of diphtheria toxin with membranes. Biochemistry (1995) 1.47
Interaction of alpha-crystallin with spin-labeled peptides. Biochemistry (1995) 1.44
Protein global fold determination using site-directed spin and isotope labeling. Protein Sci (2000) 1.42
The aggregation state of spin-labeled melittin in solution and bound to phospholipid membranes: evidence that membrane-bound melittin is monomeric. Proteins (1988) 1.38
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study. Biochemistry (1995) 1.37
Effects of lipid environment on the light-induced conformational changes of rhodopsin. 2. Roles of lipid chain length, unsaturation, and phase state. Biochemistry (1985) 1.37
The interaction of small molecules with spin-labelled erythrocyte membranes. Biochim Biophys Acta (1970) 1.35
Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase. J Gen Physiol (1994) 1.32
Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors. J Biol Chem (1984) 1.31
Identification of a subunit interface in transthyretin amyloid fibrils: evidence for self-assembly from oligomeric building blocks. Biochemistry (2001) 1.30
Electrogenic H+/OH- movement across phospholipid vesicles measured by spin-labeled hydrophobic ions. Biophys J (1983) 1.30
Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study. Biochemistry (1999) 1.30
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8. Biochemistry (2001) 1.29
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation. Biochemistry (1996) 1.28
Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study. Biochemistry (1999) 1.28
Immunospecific targeting of liposomes to cells: a novel and efficient method for covalent attachment of Fab' fragments via disulfide bonds. Biochemistry (1981) 1.27
A method for distance determination in proteins using a designed metal ion binding site and site-directed spin labeling: evaluation with T4 lysozyme. Proc Natl Acad Sci U S A (1995) 1.27
Photoactivated conformational changes in rhodopsin: a time-resolved spin label study. Science (1993) 1.27
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli. Biochemistry (1999) 1.26
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. Proc Natl Acad Sci U S A (1997) 1.25
cGMP binding sites on photoreceptor phosphodiesterase: role in feedback regulation of visual transduction. Proc Natl Acad Sci U S A (1994) 1.24
Membrane-mediated assembly of annexins studied by site-directed spin labeling. J Biol Chem (1998) 1.23
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels. Biochemistry (1996) 1.21
Determination of electrostatic potentials at biological interfaces using electron-electron double resonance. Biophys J (1992) 1.21
Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study. Biochemistry (1999) 1.21
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries. Proc Natl Acad Sci U S A (1991) 1.20
Estimation of transmembrane potentials from phase equilibria of hydrophobic paramagnetic ions. Biochemistry (1978) 1.19
Lateral phase separations in membranes. J Supramol Struct (1973) 1.16
Noncatalytic cGMP-binding sites of amphibian rod cGMP phosphodiesterase control interaction with its inhibitory gamma-subunits. A putative regulatory mechanism of the rod photoresponse. J Biol Chem (1992) 1.16
Regulation of transducin GTPase activity in bovine rod outer segments. J Biol Chem (1994) 1.16
The metabolism of gamma aminobutyric acid in the lobster nervous system. Enzymes in single excitatory and inhibitory axons. J Cell Biol (1970) 1.16
Side chain mobility and ligand interactions of the G strand of tear lipocalins by site-directed spin labeling. Biochemistry (1999) 1.15
Transmembrane electrical currents of spin-labeled hydrophobic ions. Biophys J (1982) 1.14
Purification of rhodopsin on hydroxyapatite columns, detergent exchange, and recombination with phospholipids. Methods Enzymol (1982) 1.14
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state. Proc Natl Acad Sci U S A (1997) 1.13
Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli. Biochemistry (1995) 1.12
Site-directed spin labeling of proteins. Applications to diphtheria toxin. Methods Mol Biol (2000) 1.11
Frog rod outer segments with attached inner segment ellipsoids as an in vitro model for photoreceptors on the retina. J Gen Physiol (1985) 1.10
Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli. Proc Natl Acad Sci U S A (1995) 1.09
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase. Biochemistry (1999) 1.08
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358). Biochemistry (1995) 1.08
Light-induced interfacial potentials in photoreceptor membranes. Biophys J (1980) 1.08
Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles. Biochim Biophys Acta (1973) 1.08
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325). Biochemistry (1995) 1.08
Biochemical steps in visual transduction: roles for nucleotides and calcium ions. Photochem Photobiol (1980) 1.08
Effects of lipid environment on the light-induced conformational changes of rhodopsin. 1. Absence of metarhodopsin II production in dimyristoylphosphatidylcholine recombinant membranes. Biochemistry (1985) 1.08
The effect of two inhalation anesthetics on the order of spin-labeled phospholipid vesicles. Biochim Biophys Acta (1973) 1.07
Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies. J Biol Chem (2001) 1.07
Light-induced dephosphorylation of two proteins in frog rod outer segments: influence of cyclic nucleotides and calcium. J Gen Physiol (1979) 1.06
Phospholipid asymmetry and transmembrane diffusion in photoreceptor disc membranes. Biochemistry (1993) 1.06
Influence of light and calcium on guanosine 5'-triphosphate in isolated frog rod outer segments. J Gen Physiol (1979) 1.06
Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop. Biochemistry (1999) 1.05