Published in Biochemistry on December 25, 2001
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation. Proc Natl Acad Sci U S A (2008) 5.06
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors. Pharmacol Ther (2006) 3.15
G protein coupled receptor structure and activation. Biochim Biophys Acta (2006) 2.48
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation. Proc Natl Acad Sci U S A (2003) 2.21
G protein-coupled receptor rhodopsin: a prospectus. Annu Rev Physiol (2002) 2.08
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Molecular dynamics investigation of primary photoinduced events in the activation of rhodopsin. Biophys J (2002) 1.62
Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation. Biophys J (2007) 1.37
First principles predictions of the structure and function of g-protein-coupled receptors: validation for bovine rhodopsin. Biophys J (2004) 1.30
The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors. Annu Rev Biophys Biomol Struct (2003) 1.27
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Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence. Proc Natl Acad Sci U S A (2002) 1.18
Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. Biophys J (2004) 1.17
Structural and dynamic effects of cholesterol at preferred sites of interaction with rhodopsin identified from microsecond length molecular dynamics simulations. Proteins (2009) 1.16
Modeling activated states of GPCRs: the rhodopsin template. J Comput Aided Mol Des (2006) 1.06
Concerted interconversion between ionic lock substates of the beta(2) adrenergic receptor revealed by microsecond timescale molecular dynamics. Biophys J (2010) 1.04
Atomistic insights into rhodopsin activation from a dynamic model. J Am Chem Soc (2008) 1.00
Structure and function of G protein-coupled receptors using NMR spectroscopy. Prog Nucl Magn Reson Spectrosc (2010) 1.00
Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment. J Struct Biol (2007) 0.86
NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation. Biochem Biophys Res Commun (2009) 0.84
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A hypothesis for GPCR activation. J Mol Model (2005) 0.83
Active state-like conformational elements in the beta2-AR and a photoactivated intermediate of rhodopsin identified by dynamic properties of GPCRs. Biochemistry (2008) 0.82
Electron paramagnetic resonance study of structural changes in the O photointermediate of bacteriorhodopsin. J Mol Biol (2006) 0.81
Helix 8 plays a crucial role in bradykinin B(2) receptor trafficking and signaling. J Biol Chem (2011) 0.80
Terahertz spectroscopy of bacteriorhodopsin and rhodopsin: similarities and differences. Biophys J (2008) 0.80
Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints. Protein Sci (2003) 0.80
A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors. BMC Biophys (2012) 0.79
The role of membrane curvature elastic stress for function of rhodopsin-like G protein-coupled receptors. Biochimie (2014) 0.79
Agonist-dependent phosphorylation of the formyl peptide receptor is regulated by the membrane proximal region of the cytoplasmic tail. Biochim Biophys Acta (2008) 0.79
Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics. J Biol Chem (2015) 0.77
Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data. J Mol Model (2005) 0.77
Differential dynamics of extracellular and cytoplasmic domains in denatured States of rhodopsin. Biochemistry (2014) 0.77
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In silico analysis of the histaprodifen induced activation pathway of the guinea-pig histamine H(1)-receptor. J Comput Aided Mol Des (2010) 0.75
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