Published in Proc Natl Acad Sci U S A on April 01, 1990
Cloning, characterization, and expression of a cDNA encoding a 50-kilodalton protein specifically induced by cold acclimation in wheat. Plant Physiol (1992) 2.38
Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824. J Bacteriol (1994) 1.87
Osmoprotective compounds in the Plumbaginaceae: a natural experiment in metabolic engineering of stress tolerance. Proc Natl Acad Sci U S A (1994) 1.73
Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes. J Bacteriol (1996) 1.50
'Unknown' proteins and 'orphan' enzymes: the missing half of the engineering parts list--and how to find it. Biochem J (2009) 1.47
Protein changes in response to progressive water deficit in maize . Quantitative variation and polypeptide identification Plant Physiol (1998) 1.46
Genetic engineering of glycinebetaine production toward enhancing stress tolerance in plants: metabolic limitations. Plant Physiol (2000) 1.42
aldB, an RpoS-dependent gene in Escherichia coli encoding an aldehyde dehydrogenase that is repressed by Fis and activated by Crp. J Bacteriol (1995) 1.28
Molecular cloning and DNA sequencing of the Escherichia coli K-12 ald gene encoding aldehyde dehydrogenase. J Bacteriol (1991) 1.25
NAD-dependent DNA-binding activity of the bifunctional NadR regulator of Salmonella typhimurium. J Bacteriol (1999) 1.23
Cloning of genes coding for L-sorbose and L-sorbosone dehydrogenases from Gluconobacter oxydans and microbial production of 2-keto-L-gulonate, a precursor of L-ascorbic acid, in a recombinant G. oxydans strain. Appl Environ Microbiol (1997) 1.20
Genes for direct methylation of glycine provide high levels of glycinebetaine and abiotic-stress tolerance in Synechococcus and Arabidopsis. Proc Natl Acad Sci U S A (2005) 1.11
Differential responses of nitrogen-fixing cyanobacteria to salinity and osmotic stresses. Appl Environ Microbiol (1993) 1.10
Molecular cloning of the mitochondrial aldehyde dehydrogenase gene of Saccharomyces cerevisiae by genetic complementation. J Bacteriol (1991) 1.02
Long-chain aldehyde dehydrogenase that participates in n-alkane utilization and wax ester synthesis in Acinetobacter sp. strain M-1. Appl Environ Microbiol (2000) 1.00
Synthesis of glycine betaine from exogenous choline in the moderately halophilic bacterium halomonas elongata Appl Environ Microbiol (1998) 0.99
Aldehyde Dehydrogenases in Arabidopsis thaliana: Biochemical Requirements, Metabolic Pathways, and Functional Analysis. Front Plant Sci (2011) 0.97
Rapid purification and properties of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa. J Bacteriol (1999) 0.95
Characterization of the major fragance gene from an aromatic japonica rice and analysis of its diversity in Asian cultivated rice. Theor Appl Genet (2008) 0.94
Purification and properties of betaine aldehyde dehydrogenase from Avena sativa. J Plant Res (2003) 0.89
Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria. Br J Clin Pharmacol (2003) 0.88
An unusual posttranscriptional processing in two betaine aldehyde dehydrogenase loci of cereal crops directed by short, direct repeats in response to stress conditions. Plant Physiol (2007) 0.83
Comparative proteomic analysis of longan (Dimocarpus longan Lour.) seed abortion. Planta (2010) 0.82
Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases. Protein Sci (2006) 0.82
The choline-converting pathway in Staphylococcus xylosus C2A: genetic and physiological characterization. J Bacteriol (1999) 0.81
Contribution and distribution of inorganic ions and organic compounds to the osmotic adjustment in Halostachys caspica response to salt stress. Sci Rep (2015) 0.80
Plastid-expressed choline monooxygenase gene improves salt and drought tolerance through accumulation of glycine betaine in tobacco. Plant Cell Rep (2008) 0.80
Functional analysis of BADH gene promoter from Suaeda liaotungensis K. Plant Cell Rep (2007) 0.79
TraeALDH7B1-5A, encoding aldehyde dehydrogenase 7 in wheat, confers improved drought tolerance in Arabidopsis. Planta (2015) 0.77
Enhancement of coenzyme binding by a single point mutation at the coenzyme binding domain of E. coli lactaldehyde dehydrogenase. Protein Sci (2008) 0.76
Functional and expression analyses of two kinds of betaine aldehyde dehydrogenases in a glycinebetaine-hyperaccumulating graminaceous halophyte, Leymus chinensis. Springerplus (2015) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1990) 0.75
Biophysical studies of an NAD(P)(+)-dependent aldehyde dehydrogenase from Bacillus licheniformis. Eur Biophys J (2011) 0.75
Rice choline monooxygenase (OsCMO) protein functions in enhancing glycine betaine biosynthesis in transgenic tobacco but does not accumulate in rice (Oryza sativa L. ssp. japonica). Plant Cell Rep (2012) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Production of single-stranded plasmid DNA. Methods Enzymol (1987) 39.38
Selection of AUG initiation codons differs in plants and animals. EMBO J (1987) 12.73
Molecular biology of osmoregulation. Science (1984) 8.55
Abscisic acid and water-stress induce the expression of a novel rice gene. EMBO J (1988) 6.78
Simultaneous determination of hemes a, b, and c from pyridine hemochrome spectra. Anal Biochem (1987) 5.10
Choline-glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli. J Bacteriol (1986) 4.82
Molecular Cloning of Osmotin and Regulation of Its Expression by ABA and Adaptation to Low Water Potential. Plant Physiol (1989) 3.28
Influence of single amino acid substitutions on electrophoretic mobility of sodium dodecyl sulfate-protein complexes. Biochem Biophys Res Commun (1978) 3.26
DNA sequences required for anaerobic expression of the maize alcohol dehydrogenase 1 gene. Proc Natl Acad Sci U S A (1987) 3.06
Betaine synthesis in chenopods: Localization in chloroplasts. Proc Natl Acad Sci U S A (1985) 2.61
Transcriptional and post-transcriptional regulation of storage protein gene expression in sulfur-deficient pea seeds. Nucleic Acids Res (1985) 2.44
Ion Homeostasis in Chloroplasts under Salinity and Mineral Deficiency : I. Solute Concentrations in Leaves and Chloroplasts from Spinach Plants under NaCl or NaNO(3) Salinity. Plant Physiol (1988) 2.15
The Pseudomonas oleovorans alkBAC operon encodes two structurally related rubredoxins and an aldehyde dehydrogenase. J Biol Chem (1989) 1.83
Time Course of mRNA Induction Elicited by Salt Stress in the Common Ice Plant (Mesembryanthemum crystallinum). Plant Physiol (1989) 1.81
Protons, osmolytes, and fitness of internal milieu for protein function. Am J Physiol (1986) 1.80
Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2. Proc Natl Acad Sci U S A (1985) 1.75
Cloning and characterization of the aldA gene of Aspergillus nidulans. Gene (1987) 1.70
Molecular cloning of cDNA for Avena phytochrome. Proc Natl Acad Sci U S A (1984) 1.38
Betaine aldehyde oxidation by spinach chloroplasts. Plant Physiol (1986) 1.34
The cytoplasmic isoenzyme of horse liver aldehyde dehydrogenase. Relationship to the corresponding human isoenzyme. Eur J Biochem (1984) 1.32
A rapid single-stranded cloning, sequencing, insertion, and deletion strategy. Methods Enzymol (1987) 1.29
Regulation of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (AldDH) in Aspergillus nidulans. Proc R Soc Lond B Biol Sci (1983) 1.26
Betaine accumulation and betaine-aldehyde dehydrogenase in spinach leaves. Plant Physiol (1981) 1.22
Betaine aldehyde dehydrogenase from spinach leaves: purification, in vitro translation of the mRNA, and regulation by salinity. Arch Biochem Biophys (1989) 1.20
Mitochondrial aldehyde dehydrogenase from horse liver. Correlations of the same species variants for both the cytosolic and the mitochondrial forms of an enzyme. Eur J Biochem (1988) 1.15
Betaine aldehyde dehydrogenase polymorphism in spinach: genetic and biochemical characterization. Biochem Genet (1988) 1.10
Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase. Proc Natl Acad Sci U S A (1988) 1.09
Primary structures of rat and bovine liver mitochondrial aldehyde dehydrogenases deduced from cDNA sequences. Eur J Biochem (1989) 1.09
Purification of betaine-aldehyde dehydrogenase from spinach leaves and preparation of its antibody. J Biochem (1987) 1.00
Betaine aldehyde dehydrogenase: assay and partial purification. Biochim Biophys Acta (1968) 0.79
Prokaryotic osmoregulation: genetics and physiology. Annu Rev Microbiol (1991) 7.57
Relationship between Ethylene Evolution and Senescence in Morning-Glory Flower Tissue. Plant Physiol (1976) 7.46
Water potential in excised leaf tissue: comparison of a commercial dew point hygrometer and a thermocouple psychrometer on soybean, wheat, and barley. Plant Physiol (1978) 4.12
Amino Acids Translocated from Turgid and Water-stressed Barley Leaves: I. Phloem Exudation Studies. Plant Physiol (1979) 2.45
Water stress enhances expression of an alpha-amylase gene in barley leaves. Plant Physiol (1986) 2.35
Induction of lactate dehydrogenase isozymes by oxygen deficit in barley root tissue. Plant Physiol (1986) 2.31
Radiotracer evidence implicating phosphoryl and phosphatidyl bases as intermediates in betaine synthesis by water-stressed barley leaves. Plant Physiol (1981) 2.04
S-methylmethionine plays a major role in phloem sulfur transport and is synthesized by a novel type of methyltransferase. Plant Cell (1999) 1.86
Metabolic engineering of plants for osmotic stress resistance. Curr Opin Plant Biol (1999) 1.82
Evidence for a ferredoxin-dependent choline monooxygenase from spinach chloroplast stroma. Plant Physiol (1989) 1.78
A new route for synthesis of dimethylsulphoniopropionate in marine algae. Nature (1997) 1.69
Purification and characterization of a novel methyltransferase responsible for biosynthesis of halomethanes and methanethiol in Brassica oleracea. J Biol Chem (1995) 1.60
Purification and properties of hypoxically induced lactate dehydrogenase from barley roots. Plant Physiol (1986) 1.45
Proline Accumulation in Water-stressed Barley Leaves in Relation to Translocation and the Nitrogen Budget. Plant Physiol (1979) 1.41
Enhanced synthesis of choline and glycine betaine in transgenic tobacco plants that overexpress phosphoethanolamine N-methyltransferase. Proc Natl Acad Sci U S A (2001) 1.39
Plants synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme. J Biol Chem (2001) 1.38
The endogenous choline supply limits glycine betaine synthesis in transgenic tobacco expressing choline monooxygenase. Plant J (1998) 1.38
Oxygen-18 and deuterium labeling studies of choline oxidation by spinach and sugar beet. Plant Physiol (1988) 1.35
Purification and properties of S-adenosyl-L-methionine:L-methionine S-methyltransferase from Wollastonia biflora leaves. J Biol Chem (1995) 1.35
Betaine aldehyde oxidation by spinach chloroplasts. Plant Physiol (1986) 1.34
cDNA cloning of phosphoethanolamine N-methyltransferase from spinach by complementation in Schizosaccharomyces pombe and characterization of the recombinant enzyme. J Biol Chem (2000) 1.33
Choline monooxygenase, an unusual iron-sulfur enzyme catalyzing the first step of glycine betaine synthesis in plants: prosthetic group characterization and cDNA cloning. Proc Natl Acad Sci U S A (1997) 1.30
Salt-inducible betaine aldehyde dehydrogenase from sugar beet: cDNA cloning and expression. Plant Mol Biol (1992) 1.26
Hypoxically inducible barley lactate dehydrogenase: cDNA cloning and molecular analysis. Proc Natl Acad Sci U S A (1990) 1.25
Three alcohol dehydrogenase genes in wild and cultivated barley: characterization of the products of variant alleles. Biochem Genet (1984) 1.23
Betaine aldehyde dehydrogenase from spinach leaves: purification, in vitro translation of the mRNA, and regulation by salinity. Arch Biochem Biophys (1989) 1.20
Dimethylsulfoniopropionate biosynthesis in Spartina alterniflora1. Evidence that S-methylmethionine and dimethylsulfoniopropylamine are intermediates. Plant Physiol (1998) 1.19
Evidence implicating dimethylsulfoniopropionaldehyde as an intermediate in dimethylsulfoniopropionate biosynthesis. Plant Physiol (1995) 1.18
Betaine deficiency in maize : complementation tests and metabolic basis. Plant Physiol (1991) 1.16
The S-methylmethionine cycle in angiosperms: ubiquity, antiquity and activity. Plant J (2001) 1.15
Betaine-aldehyde dehydrogenase from amaranth leaves efficiently catalyzes the NAD-dependent oxidation of dimethylsulfoniopropionaldehyde to dimethylsulfoniopropionate. Arch Biochem Biophys (1997) 1.13
Betaine aldehyde dehydrogenase polymorphism in spinach: genetic and biochemical characterization. Biochem Genet (1988) 1.10
Choline oxidation by intact spinach chloroplasts. Plant Physiol (1988) 1.08
Isolation, characterization, and functional expression of cDNAs encoding NADH-dependent methylenetetrahydrofolate reductase from higher plants. J Biol Chem (1999) 1.04
Metabolic modeling identifies key constraints on an engineered glycine betaine synthesis pathway in tobacco. Plant Physiol (2000) 1.02
Radiotracer and computer modeling evidence that phospho-base methylation is the main route of choline synthesis in tobacco. Plant Physiol (2000) 1.02
Characterization and functional expression of cDNAs encoding methionine-sensitive and -insensitive homocysteine S-methyltransferases from Arabidopsis. J Biol Chem (2000) 0.99
Salinity promotes accumulation of 3-dimethylsulfoniopropionate and its precursor S-methylmethionine in chloroplasts. Plant Physiol (1998) 0.88
Comparative biochemical and immunological studies of the glycine betaine synthesis pathway in diverse families of dicotyledons. Planta (1989) 0.87
Osmotic stress induces expression of choline monooxygenase in sugar beet and amaranth. Plant Physiol (1998) 0.87
Induction of a Specific N-Methyltransferase Enzyme by Long-Term Heat Stress during Barley Leaf Growth. Plant Physiol (1985) 0.85
Choline import into chloroplasts limits glycine betaine synthesis in tobacco: analysis of plants engineered with a chloroplastic or a cytosolic pathway. Metab Eng (2000) 0.79
Biochemical evidence for two novel enzymes in the biosynthesis of 3-dimethylsulfoniopropionate in Spartina alterniflora. Plant Physiol (2000) 0.78
Translocation and metabolism of glycine betaine by barley plants in relation to water stress. Planta (1980) 0.78
Sucrose suppression of chlorophyll synthesis in carrot callus cultures. Planta (1971) 0.76
Water stress provokes a generalized increase in phosphatidylcholine turnover in barley leaves. Planta (1982) 0.75
Sucrose suppression of chlorophyll synthesis in carrot tissue cultures: The role of invertase. Planta (1971) 0.75