Published in RNA Biol on December 10, 2012
A splicing-dependent transcriptional checkpoint associated with prespliceosome formation. Mol Cell (2014) 1.73
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The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes Dev (2015) 0.91
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A protein map of the yeast activated spliceosome as obtained by electron microscopy. RNA (2016) 0.76
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Rapid, transcript-specific changes in splicing in response to environmental stress. Mol Cell (2007) 2.58
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The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell (2009) 2.39
Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis. Mol Cell (2009) 2.36
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Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics (2001) 2.18
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A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol (2008) 2.12
The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell (2006) 2.09
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Dynamic protein-protein interaction wiring of the human spliceosome. Mol Cell (2012) 2.04
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation. Genes Dev (1987) 1.99
The DECD box putative ATPase Sub2p is an early mRNA export factor. Curr Biol (2001) 1.98
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RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem (2009) 1.93
Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev (2001) 1.91
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2. Genes Dev (2005) 1.90
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nat Struct Mol Biol (2009) 1.89
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Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA (2010) 1.85
The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol (2005) 1.82
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing. RNA (1995) 1.77
The cap and the 3' splice site similarly affect polyadenylation efficiency. Mol Cell Biol (1996) 1.75
Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. Am J Hum Genet (2009) 1.73
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nat Struct Mol Biol (2008) 1.73
Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol (2004) 1.70
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The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol (2006) 1.70
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How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing. RNA (2002) 1.64
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Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol (1999) 1.56
Rearrangement of competing U2 RNA helices within the spliceosome promotes multiple steps in splicing. Genes Dev (2007) 1.53
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Prp8 protein: at the heart of the spliceosome. RNA (2005) 2.89
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Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast. Proc Natl Acad Sci U S A (2011) 1.85
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Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol (2004) 1.70
Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol (2006) 1.38
prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol (2007) 1.32
Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors. RNA (2003) 1.31
Lsm proteins promote regeneration of pre-mRNA splicing activity. Curr Biol (2004) 1.21
Lsm proteins are required for normal processing of pre-tRNAs and their efficient association with La-homologous protein Lhp1p. Mol Cell Biol (2002) 1.20
Nuclear pre-mRNA decapping and 5' degradation in yeast require the Lsm2-8p complex. Mol Cell Biol (2004) 1.19
Prp8p dissection reveals domain structure and protein interaction sites. RNA (2005) 1.15
Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning. Genes Dev (2012) 1.13
Structure, function and regulation of spliceosomal RNA helicases. Curr Opin Cell Biol (2012) 1.10
Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev (2011) 1.01
Modelling reveals kinetic advantages of co-transcriptional splicing. PLoS Comput Biol (2011) 0.99
Cross-talk in transcription, splicing and chromatin: who makes the first call? Biochem Soc Trans (2010) 0.99
Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. RNA (2009) 0.98
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Kinetic analysis of pre-ribosome structure in vivo. RNA (2012) 0.94
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Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8. RNA (2009) 0.86
Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes. Hum Mutat (2010) 0.84
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Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev (2013) 0.83
Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events. RNA Biol (2009) 0.82
Processivity and coupling in messenger RNA transcription. PLoS One (2010) 0.80
A rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation. J R Soc Interface (2013) 0.78
Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast. FEBS J (2009) 0.77