SF1 and SF2 helicases: family matters.

Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system. EMBO J (2011) 3.81

Structural insights into RNA recognition by RIG-I. Cell (2011) 3.25

Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature (2011) 3.05

Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics (2013) 2.70

RNA helicases at work: binding and rearranging. Trends Biochem Sci (2011) 2.42

RNA degradation in Saccharomyces cerevisae. Genetics (2012) 2.06

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes. Cell (2013) 2.04

Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability. Mol Cell (2014) 1.95

Human RecQ helicases in DNA repair, recombination, and replication. Annu Rev Biochem (2014) 1.68

Recognition of the pre-miRNA structure by Drosophila Dicer-1. Nat Struct Mol Biol (2011) 1.61

Highlights of the DNA cutters: a short history of the restriction enzymes. Nucleic Acids Res (2013) 1.60

Structural basis for the prion-like MAVS filaments in antiviral innate immunity. Elife (2014) 1.56

Type I restriction enzymes and their relatives. Nucleic Acids Res (2013) 1.54

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling. EMBO Rep (2011) 1.47

P body-associated protein Mov10 inhibits HIV-1 replication at multiple stages. J Virol (2010) 1.40

The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex. Mol Cell (2011) 1.38

DEAD-box proteins as RNA helicases and chaperones. Wiley Interdiscip Rev RNA (2011) 1.37

A structure-based model of RIG-I activation. RNA (2012) 1.33

RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27

Dynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primase. Curr Opin Chem Biol (2011) 1.24

DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster. Nucleic Acids Res (2012) 1.20

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly. Nat Struct Mol Biol (2012) 1.20

RNA helicase proteins as chaperones and remodelers. Annu Rev Biochem (2014) 1.17

Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p. Nature (2012) 1.16

Toward a molecular understanding of RNA remodeling by DEAD-box proteins. RNA Biol (2012) 1.16

DEAD-box helicases as integrators of RNA, nucleotide and protein binding. Biochim Biophys Acta (2013) 1.16

The RNA helicase database. Nucleic Acids Res (2010) 1.15

RNA helicases in splicing. RNA Biol (2012) 1.13

A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast. Nat Struct Mol Biol (2013) 1.12

Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex. ACS Chem Biol (2013) 1.12

Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing. RNA Biol (2012) 1.10

Identification of residues in chromodomain helicase DNA-binding protein 1 (Chd1) required for coupling ATP hydrolysis to nucleosome sliding. J Biol Chem (2011) 1.08

Specificity and nonspecificity in RNA-protein interactions. Nat Rev Mol Cell Biol (2015) 1.08

Structural insights into regulation and action of SWI2/SNF2 ATPases. Curr Opin Struct Biol (2011) 1.07

Nucleosome remodeling and epigenetics. Cold Spring Harb Perspect Biol (2013) 1.07

The thermodynamic basis for viral RNA detection by the RIG-I innate immune sensor. J Biol Chem (2012) 1.06

Plasmodium falciparum XPD translocates in 5' to 3' direction, is expressed throughout the blood stages, and interacts with p44. Protoplasma (2015) 1.05

The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annu Rev Biochem (2015) 1.04

Synergistic activation of eIF4A by eIF4B and eIF4G. Nucleic Acids Res (2010) 1.04

Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines. Curr Opin Struct Biol (2012) 1.04

Fitting CRISPR-associated Cas3 into the helicase family tree. Curr Opin Struct Biol (2014) 1.04

Regulation of translocation polarity by helicase domain 1 in SF2B helicases. EMBO J (2011) 1.04

Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains. Nucleic Acids Res (2012) 1.04

Sequence-dependent base pair stepping dynamics in XPD helicase unwinding. Elife (2013) 1.02

Structure, function and regulation of CSB: a multi-talented gymnast. Mech Ageing Dev (2013) 1.02

RNA helicases: diverse roles in prokaryotic response to abiotic stress. RNA Biol (2012) 1.01

On the importance of cotranscriptional RNA structure formation. RNA (2013) 1.01

The Azoarcus group I intron ribozyme misfolds and is accelerated for refolding by ATP-dependent RNA chaperone proteins. J Biol Chem (2011) 1.00

RNA folding in living cells. RNA Biol (2010) 1.00

Mechanism and regulation of the nonsense-mediated decay pathway. Nucleic Acids Res (2016) 0.99

Structural insights into RNA recognition and activation of RIG-I-like receptors. Curr Opin Struct Biol (2012) 0.99

Roles of DEAD-box proteins in RNA and RNP Folding. RNA Biol (2010) 0.99

Ski2-like RNA helicase structures: common themes and complex assemblies. RNA Biol (2012) 0.97

Structural insights into the activation of RIG-I, a nanosensor for viral RNAs. EMBO Rep (2011) 0.97

Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNA. J Biol Chem (2013) 0.96

Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry. Nucleic Acids Res (2013) 0.96

Chromosome Compaction by Active Loop Extrusion. Biophys J (2016) 0.95

RNA BIOCHEMISTRY. Factor-dependent processivity in human eIF4A DEAD-box helicase. Science (2015) 0.95

Breaking bad: R-loops and genome integrity. Trends Cell Biol (2015) 0.95

Disease-causing missense mutations in human DNA helicase disorders. Mutat Res (2012) 0.95

Novel ATP-independent RNA annealing activity of the dengue virus NS3 helicase. PLoS One (2012) 0.95

RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex. Proc Natl Acad Sci U S A (2012) 0.93

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease. Pharmacol Rev (2015) 0.92

The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase. PLoS One (2013) 0.92

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc Natl Acad Sci U S A (2016) 0.92

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease. Adv Exp Med Biol (2014) 0.92

ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities. Proc Natl Acad Sci U S A (2013) 0.91

Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs. Proc Natl Acad Sci U S A (2012) 0.91

Chromatin remodeling during glucocorticoid receptor regulated transactivation. Biochim Biophys Acta (2012) 0.91

The MOV10 helicase inhibits LINE-1 mobility. J Biol Chem (2013) 0.90

'Black sheep' that don't leave the double-stranded RNA-binding domain fold. Trends Biochem Sci (2014) 0.90

Mechanism of start site selection by RNA polymerase II: interplay between TFIIB and Ssl2/XPB helicase subunit of TFIIH. J Biol Chem (2011) 0.90

ATP-dependent roles of the DEAD-box protein Mss116p in group II intron splicing in vitro and in vivo. J Mol Biol (2011) 0.90

Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities. Nat Commun (2015) 0.90

Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity. J Biol Chem (2014) 0.90

Superfamily 2 helicases. Front Biosci (Landmark Ed) (2012) 0.89

Electron microscopy studies of nucleosome remodelers. Curr Opin Struct Biol (2011) 0.89

Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit. RNA (2013) 0.88

Mitochondrial ribosome assembly in health and disease. Cell Cycle (2015) 0.88

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev (2015) 0.88

Positive evolutionary selection on the RIG-I-like receptor genes in mammals. PLoS One (2013) 0.88

Type III restriction endonuclease EcoP15I is a heterotrimeric complex containing one Res subunit with several DNA-binding regions and ATPase activity. Nucleic Acids Res (2011) 0.87

Crystal structure of the superfamily 1 helicase from Tomato mosaic virus. J Virol (2012) 0.87

Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biol (2014) 0.87

Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni. PLoS Negl Trop Dis (2012) 0.86

Unwinding and rewinding: double faces of helicase? J Nucleic Acids (2012) 0.86

Mov10 and APOBEC3G localization to processing bodies is not required for virion incorporation and antiviral activity. J Virol (2013) 0.86

Grip it and rip it: structural mechanisms of DNA helicase substrate binding and unwinding. Protein Sci (2014) 0.86

Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control. RNA Biol (2012) 0.86

Structure and Mechanisms of SF1 DNA Helicases. Adv Exp Med Biol (2013) 0.86

Generation of a mouse model for studying the role of upregulated RTEL1 activity in tumorigenesis. Transgenic Res (2012) 0.86

Phylogenetic distribution and evolutionary history of bacterial DEAD-Box proteins. J Mol Evol (2011) 0.86

Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases. Proc Natl Acad Sci U S A (2015) 0.86

Saccharomyces cerevisiae Sen1 as a model for the study of mutations in human Senataxin that elicit cerebellar ataxia. Genetics (2014) 0.85

Regulation of DEAH/RHA helicases by G-patch proteins. Biomed Res Int (2015) 0.85

DEAD-box protein CYT-19 is activated by exposed helices in a group I intron RNA. Proc Natl Acad Sci U S A (2014) 0.85

Drosophila dicer-2 cleavage is mediated by helicase- and dsRNA termini-dependent states that are modulated by Loquacious-PD. Mol Cell (2015) 0.84

The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1. Nucleic Acids Res (2012) 0.84

The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection. Nucleic Acids Res (2015) 0.84

Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife (2015) 0.84

WebLogo: a sequence logo generator. Genome Res (2004) 59.58

Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature (2001) 38.75

Structure and mechanism of helicases and nucleic acid translocases. Annu Rev Biochem (2007) 7.83

Classification and evolution of P-loop GTPases and related ATPases. J Mol Biol (2002) 6.85

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism. Cell (1999) 6.84

The DEAD-box protein family of RNA helicases. Gene (2005) 6.10

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding. Structure (1998) 5.83

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity (2009) 5.70

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell (2006) 5.70

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I. Mol Cell (2008) 5.35

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell (2008) 5.20

Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks. Nature (2004) 4.35

Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res (2002) 4.00

Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA. Science (2009) 4.00

Translocation and unwinding mechanisms of RNA and DNA helicases. Annu Rev Biophys (2008) 3.86

Spring-loaded mechanism of DNA unwinding by hepatitis C virus NS3 helicase. Science (2007) 3.70

UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke. Cell (2006) 3.65

RecQ helicases: multifunctional genome caretakers. Nat Rev Cancer (2009) 3.63

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA. Science (2006) 3.60

The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell (2006) 3.51

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase. Structure (1999) 3.37

Dead-box proteins: a family affair--active and passive players in RNP-remodeling. Nucleic Acids Res (2006) 3.26

XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell (2008) 3.14

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I. Proc Natl Acad Sci U S A (2009) 3.05

X-ray structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase core and its complex with DNA. Cell (2005) 3.04

Non-hexameric DNA helicases and translocases: mechanisms and regulation. Nat Rev Mol Cell Biol (2008) 3.00

Structural mechanism of RNA recognition by the RIG-I-like receptors. Immunity (2008) 2.81

Structural basis for DNA duplex separation by a superfamily-2 helicase. Nat Struct Mol Biol (2007) 2.77

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding. EMBO J (2002) 2.52

The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis. Mol Cell (2003) 2.51

Structural analysis of DNA replication fork reversal by RecG. Cell (2001) 2.44

Virus-encoded RNA helicases. J Virol (1997) 2.39

Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis. Mol Cell (2009) 2.36

RNA helicases--one fold for many functions. Curr Opin Struct Biol (2007) 2.34

The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases. Nat Struct Mol Biol (2006) 2.34

Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism. EMBO J (2000) 2.27

Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54. Nat Struct Mol Biol (2005) 2.25

Powering through ribosome assembly. RNA (2009) 2.19

Structure of the DNA repair helicase XPD. Cell (2008) 2.16

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding. Proc Natl Acad Sci U S A (2008) 2.14

Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein. EMBO J (2008) 1.99

Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain. Proc Natl Acad Sci U S A (2005) 1.95

Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proc Natl Acad Sci U S A (2009) 1.94

Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure (2008) 1.86

DEAD-box proteins unwind duplexes by local strand separation. Mol Cell (2007) 1.85

Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81

Enzymic unwinding of DNA. 2. Chain separation by an ATP-dependent DNA unwinding enzyme. Eur J Biochem (1976) 1.79

Studies on three E. coli DEAD-box helicases point to an unwinding mechanism different from that of model DNA helicases. Biochemistry (2004) 1.76

Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures. Nucleic Acids Res (2006) 1.73

DEAD-box proteins can completely separate an RNA duplex using a single ATP. Proc Natl Acad Sci U S A (2008) 1.72

Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidance, encodes a 3' to 5' DNA helicase. J Biol Chem (2005) 1.69

Mechanistic basis of 5'-3' translocation in SF1B helicases. Cell (2009) 1.65

Molecular genetics of RecQ helicase disorders. Cell Mol Life Sci (2007) 1.64

Structural and functional insights into the human Upf1 helicase core. EMBO J (2006) 1.61

Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases. Nucleic Acids Res (2006) 1.61

Site-directed mutagenesis of motif III in PcrA helicase reveals a role in coupling ATP hydrolysis to strand separation. Nucleic Acids Res (1999) 1.60

Crystal structure and functional implications of Pyrococcus furiosus hef helicase domain involved in branched DNA processing. Structure (2005) 1.59

The Pif1p subfamily of helicases: region-specific DNA helicases? Trends Cell Biol (2001) 1.57

A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol Cell (2008) 1.52

Structure of the human RECQ1 helicase reveals a putative strand-separation pin. Proc Natl Acad Sci U S A (2009) 1.52

Nonspecific binding to structured RNA and preferential unwinding of an exposed helix by the CYT-19 protein, a DEAD-box RNA chaperone. Proc Natl Acad Sci U S A (2006) 1.45

Structural insights into the exon junction complex. Curr Opin Struct Biol (2008) 1.44

Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA. Mol Cell (2009) 1.44

Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. EMBO J (2009) 1.44

Domain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ family. Nucleic Acids Res (2003) 1.41

Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol (2009) 1.40

The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins. Nat Struct Mol Biol (2008) 1.38

Structural basis for the function of DEAH helicases. EMBO Rep (2010) 1.34

Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Mol Cell (2009) 1.32

DNA binding to RecD: role of the 1B domain in SF1B helicase activity. EMBO J (2008) 1.32

Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex. Nucleic Acids Res (2001) 1.31

Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival. DNA Repair (Amst) (2010) 1.29

Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I. EMBO J (2008) 1.28

YxiN is a modular protein combining a DEx(D/H) core and a specific RNA-binding domain. J Biol Chem (2005) 1.24

Stepwise translocation of nucleic acid motors. Curr Opin Struct Biol (2010) 1.22

Identification of the SSB binding site on E. coli RecQ reveals a conserved surface for binding SSB's C terminus. J Mol Biol (2009) 1.20

RecQ helicases: multiple structures for multiple functions? HFSP J (2009) 1.20

Mutations in PRP43 that uncouple RNA-dependent NTPase activity and pre-mRNA splicing function. Biochemistry (2006) 1.20

Multiple functions of nuclear DNA helicase II (RNA helicase A) in nucleic acid metabolism. Acta Biochim Biophys Sin (Shanghai) (2004) 1.19

Do human RNA helicases have a role in cancer? Biochim Biophys Acta (2004) 1.19

Evolution of MDA-5/RIG-I-dependent innate immunity: independent evolution by domain grafting. Proc Natl Acad Sci U S A (2008) 1.19

Understanding helicases as a means of virus control. Curr Pharm Des (2006) 1.18

IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1). Hum Mol Genet (2009) 1.15

Plant RNA helicases: linking aberrant and silencing RNA. Trends Plant Sci (2009) 1.12

A conserved phenylalanine of motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteins. Mol Cell Biol (2008) 1.10

Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ. Nucleic Acids Res (2008) 1.07

Drosophila RecQ4 has a 3'-5' DNA helicase activity that is essential for viability. J Biol Chem (2009) 1.06

Structure of the motor subunit of type I restriction-modification complex EcoR124I. Nat Struct Mol Biol (2008) 1.06

Motif III in superfamily 2 "helicases" helps convert the binding energy of ATP into a high-affinity RNA binding site in the yeast DEAD-box protein Ded1. J Mol Biol (2009) 1.05

Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Mol Biol Evol (2001) 1.05

Overexpression of a DEAD box protein (DDX1) in neuroblastoma and retinoblastoma cell lines. J Biol Chem (1998) 1.00

A two-site kinetic mechanism for ATP binding and hydrolysis by E. coli Rep helicase dimer bound to a single-stranded oligodeoxynucleotide. J Mol Biol (1999) 0.98

A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility. Nucleic Acids Res (2008) 0.98

SrmB, a DEAD-box helicase involved in Escherichia coli ribosome assembly, is specifically targeted to 23S rRNA in vivo. Nucleic Acids Res (2009) 0.94

A conformational change in the helicase core is necessary but not sufficient for RNA unwinding by the DEAD box helicase YxiN. Nucleic Acids Res (2009) 0.93

Multiple Escherichia coli RecQ helicase monomers cooperate to unwind long DNA substrates: a fluorescence cross-correlation spectroscopy study. J Biol Chem (2010) 0.93

The NPH-II helicase displays efficient DNA x RNA helicase activity and a pronounced purine sequence bias. J Biol Chem (2010) 0.90

DEAD on. Nat Struct Mol Biol (2006) 0.80

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci U S A (2002) 3.99

From unwinding to clamping - the DEAD box RNA helicase family. Nat Rev Mol Cell Biol (2011) 3.38

Protein displacement by DExH/D "RNA helicases" without duplex unwinding. Science (2004) 3.33

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding. EMBO J (2002) 2.52

The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases. Nat Struct Mol Biol (2006) 2.34

ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1. Biochemistry (2005) 2.26

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding. Proc Natl Acad Sci U S A (2008) 2.14

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proc Natl Acad Sci U S A (2005) 2.00

Involvement of DEAD-box proteins in group I and group II intron splicing. Biochemical characterization of Mss116p, ATP hydrolysis-dependent and -independent mechanisms, and general RNA chaperone activity. J Mol Biol (2006) 1.99

Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition. Cell (2008) 1.91

DEAD-box proteins unwind duplexes by local strand separation. Mol Cell (2007) 1.85

Backbone tracking by the SF2 helicase NPH-II. Nat Struct Mol Biol (2004) 1.61

Do DEAD-box proteins promote group II intron splicing without unwinding RNA? Mol Cell (2007) 1.50

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p. RNA (2007) 1.39

The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex. Mol Cell (2011) 1.38

Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones. J Mol Biol (2009) 1.30

Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro. J Mol Biol (2007) 1.29

Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track. J Mol Biol (2006) 1.18

The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex. Cell (2011) 1.17

DEAD-box helicases as integrators of RNA, nucleotide and protein binding. Biochim Biophys Acta (2013) 1.16

The RNA helicase database. Nucleic Acids Res (2010) 1.15

Hidden specificity in an apparently nonspecific RNA-binding protein. Nature (2013) 1.13

Discriminatory RNP remodeling by the DEAD-box protein DED1. RNA (2006) 1.09

The Ded1/DDX3 subfamily of DEAD-box RNA helicases. Crit Rev Biochem Mol Biol (2014) 1.00

Discovery of antivirulence agents against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2013) 0.99

Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap. J Biol Chem (2009) 0.98

DEAD-box-protein-assisted RNA structure conversion towards and against thermodynamic equilibrium values. J Mol Biol (2007) 0.96

RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase. Biochemistry (2008) 0.96

The natural course of infantile spinal muscular atrophy with respiratory distress type 1 (SMARD1). Pediatrics (2011) 0.93

RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex. Proc Natl Acad Sci U S A (2012) 0.93

Spinal muscular atrophy with respiratory distress type 1 (SMARD1). J Child Neurol (2008) 0.91

DEAD-box helicases form nucleotide-dependent, long-lived complexes with RNA. Biochemistry (2014) 0.84

Helicase multitasking in ribosome assembly. Mol Cell (2009) 0.81

AMP sensing by DEAD-box RNA helicases. J Mol Biol (2013) 0.81

Prediction of functional tertiary interactions and intermolecular interfaces from primary sequence data. J Exp Zool B Mol Dev Evol (2005) 0.80

Biophysics: helicase snaps back. Nature (2005) 0.79

Analysis of duplex unwinding by RNA helicases using stopped-flow fluorescence spectroscopy. Methods Enzymol (2012) 0.79

An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE. Plant Cell (2013) 0.79

Biochemistry: indifferent chaperones. Nature (2007) 0.78

Unwinding initiation by the viral RNA helicase NPH-II. J Mol Biol (2011) 0.77

Methods in enzymology. Preface. Methods Enzymol (2012) 0.76

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability. RNA (2013) 0.76