Published in Proc Natl Acad Sci U S A on December 10, 2012
Protein design: toward functional metalloenzymes. Chem Rev (2014) 1.17
Designing functional metalloproteins: from structural to catalytic metal sites. Coord Chem Rev (2013) 1.10
Shaping quaternary assemblies of water-soluble non-peptide helical foldamers by sequence manipulation. Nat Chem (2015) 0.91
Designing hydrolytic zinc metalloenzymes. Biochemistry (2014) 0.91
A de novo designed metalloenzyme for the hydration of CO2. Angew Chem Int Ed Engl (2014) 0.87
Computational study of the activated O(H) state in the catalytic mechanism of cytochrome c oxidase. Proc Natl Acad Sci U S A (2013) 0.86
De novo-designed metallopeptides with type 2 copper centers: modulation of reduction potentials and nitrite reductase activities. J Am Chem Soc (2013) 0.85
De novo protein design as a methodology for synthetic bioinorganic chemistry. Acc Chem Res (2015) 0.83
Artificial metalloenzymes derived from three-helix bundles. Curr Opin Chem Biol (2015) 0.82
Histidine Orientation Modulates the Structure and Dynamics of a de Novo Metalloenzyme Active Site. J Am Chem Soc (2015) 0.78
Electron transfer activity of a de novo designed copper center in a three-helix bundle fold. Biochim Biophys Acta (2015) 0.76
Nitrite Reductase Activity in Engineered Azurin Variants. Inorg Chem (2016) 0.75
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Design of a zinc-finger hydrolase with a synthetic αββ protein. PLoS One (2014) 0.75
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Nitric oxide in biological denitrification: Fe/Cu metalloenzyme and metal complex NO(x) redox chemistry. Chem Rev (2002) 1.81
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Major changes in copper coordination accompany reduction of peptidylglycine monooxygenase: implications for electron transfer and the catalytic mechanism. J Biol Inorg Chem (2000) 1.40
An artificial di-iron oxo-protein with phenol oxidase activity. Nat Chem Biol (2009) 1.37
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The electron-accepting sites in Rhus vernicifera laccase as studied by anaerobic oxidation-reduction titrations. Eur J Biochem (1971) 1.15
Thermodynamic model for the stabilization of trigonal thiolato mercury(II) in designed three-stranded coiled coils. Biochemistry (2001) 1.15
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Binding of Cu(II) or Zn(II) in a de novo designed triple-stranded alpha-helical coiled-coil toward a prototype for a metalloenzyme. J Pept Res (2004) 1.05
Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering. Biochemistry (2012) 1.04
Thermodynamic equilibrium between blue and green copper sites and the role of the protein in controlling function. Proc Natl Acad Sci U S A (2009) 1.01
Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1. J Am Chem Soc (2011) 1.01
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An atypical linear Cu(I)-S2 center constitutes the high-affinity metal-sensing site in the CueR metalloregulatory protein. J Am Chem Soc (2003) 0.98
A random-sequential mechanism for nitrite binding and active site reduction in copper-containing nitrite reductase. J Biol Chem (2006) 0.97
Two-metal ion, Ni(II) and Cu(II), binding alpha-helical coiled coil peptide. J Am Chem Soc (2004) 0.95
Binding of nitrite and its reductive activation to nitric oxide at biomimetic copper centers. J Biol Inorg Chem (2000) 0.90
Ab initio modelling of the structure and redox behaviour of copper(I) bound to a His-His model peptide: relevance to the beta-amyloid peptide of Alzheimer's disease. J Biol Inorg Chem (2006) 0.89
Spectroscopic identification of different types of copper centers generated in synthetic four-helix bundle proteins. J Am Chem Soc (2004) 0.88
A stable hyponitrite-bridged iron porphyrin complex. J Am Chem Soc (2009) 0.86
De novo design and characterization of copper centers in synthetic four-helix-bundle proteins. J Am Chem Soc (2001) 0.86
Using synthetic chemistry to understand copper protein active sites: a personal perspective. J Biol Inorg Chem (2006) 0.83
Cu(I) binding properties of a designed metalloprotein. J Inorg Biochem (2009) 0.82
Evidence that a miniature CuI metalloprotein undergoes collisional electron transfer in the inverted Marcus region. Angew Chem Int Ed Engl (2006) 0.81
The effect of the side chain length of Asp and Glu on coordination structure of Cu(2+) in a de novo designed protein. Biopolymers (2009) 0.81
Incorporating electron-transfer functionality into synthetic metalloproteins from the bottom-up. Inorg Chem (2006) 0.81
Spectroscopic characterization of reaction intermediates in a model for copper nitrite reductase. Angew Chem Int Ed Engl (2006) 0.81
Oxygen activation in a copper-containing amine oxidase. Biochem Soc Trans (2003) 0.80
Creation of a type 1 blue copper site within a de novo coiled-coil protein scaffold. J Am Chem Soc (2010) 0.80
Creation of a binuclear purple copper site within a de novo coiled-coil protein. Biochemistry (2012) 0.79
Electroreduction of nitrite to nitrogen oxide by a copper-containing nitrite reductase model complex incorporated into collagen film. Bioelectrochemistry (2009) 0.79
Electroreduction of nitrite on gold electrode modified with Cu-containing nitrite reductase model complex. Chem Commun (Camb) (2005) 0.79
Control of enzyme reaction by a designed metal-ion-dependent α-helical coiled-coil protein. J Biol Inorg Chem (2012) 0.78
Reevaluation of copper(I) affinity for amyloid-β peptides by competition with ferrozine--an unusual copper(I) indicator. Chemistry (2011) 0.78
(N-Benzyl-bis-N',N''-salicylidene)-cis-1,3,5-triaminocyclohexane copper(II): a novel catalyst for the aerobic oxidation of benzyl alcohol. Dalton Trans (2005) 0.78
Nitrite reduction by copper complexes. Dalton Trans (2009) 0.78
The electronic structure of Mn in oxides, coordination complexes, and the oxygen-evolving complex of photosystem II studied by resonant inelastic X-ray scattering. J Am Chem Soc (2004) 2.77
Structural and functional evolution of metallacrowns. Chem Rev (2007) 2.41
Cu(I) recognition via cation-pi and methionine interactions in CusF. Nat Chem Biol (2007) 2.28
Structural, spectroscopic, and reactivity models for the manganese catalases. Chem Rev (2004) 1.60
Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of Plasmodium falciparum. Chem Biol (2012) 1.59
Comparison of the binding of cadmium(II), mercury(II), and arsenic(III) to the de novo designed peptides TRI L12C and TRI L16C. J Am Chem Soc (2002) 1.50
Hydrolytic catalysis and structural stabilization in a designed metalloprotein. Nat Chem (2011) 1.37
Isolation of the first ferromagnetically coupled Mn(III/IV) complex. Chem Commun (Camb) (2003) 1.33
An engineered pathway for the formation of protein disulfide bonds. Science (2004) 1.29
Corroborative models of the cobalt(II) inhibited Fe/Mn superoxide dismutases. Inorg Chem (2005) 1.26
Reexamination of lead(II) coordination preferences in sulfur-rich sites: implications for a critical mechanism of lead poisoning. J Am Chem Soc (2005) 1.26
Peptidic models for the binding of Pb(II), Bi(III) and Cd(II) to mononuclear thiolate binding sites. J Biol Inorg Chem (2006) 1.24
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers. ACS Nano (2008) 1.22
Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation. Science (2009) 1.21
Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils. Proc Natl Acad Sci U S A (2007) 1.19
Probing metal-protein interactions using a de novo design approach. Curr Opin Chem Biol (2005) 1.18
Reflections on Small Molecule Manganese Models that Seek to Mimic Photosynthetic Water Oxidation Chemistry. Coord Chem Rev (2008) 1.18
Protein design: toward functional metalloenzymes. Chem Rev (2014) 1.17
Preparation of highly efficient manganese catalase mimics. Inorg Chem (2002) 1.12
The PcoC copper resistance protein coordinates Cu(I) via novel S-methionine interactions. J Am Chem Soc (2003) 1.12
Understanding metalloprotein folding using a de novo design strategy. Inorg Chem (2004) 1.12
Assessing the integrity of designed homomeric parallel three-stranded coiled coils in the presence of metal ions. Inorg Chem (2006) 1.11
Designing functional metalloproteins: from structural to catalytic metal sites. Coord Chem Rev (2013) 1.10
A method for normalization of X-ray absorption spectra. J Synchrotron Radiat (2005) 1.10
Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils. Angew Chem Int Ed Engl (2006) 1.09
Synthesis and magnetic properties of a metallacryptate that behaves as a single-molecule magnet. Angew Chem Int Ed Engl (2003) 1.08
A light-dependent mechanism for massive accumulation of manganese in the photosynthetic bacterium Synechocystis sp. PCC 6803. Biochemistry (2002) 1.08
Heterochromia in designed metallopeptides: geometry-selective binding of CdII in a de novo peptide. Angew Chem Int Ed Engl (2007) 1.07
Linear free-energy analysis of mercury(II) and cadmium(II) binding to three-stranded coiled coils. Biochemistry (2005) 1.06
Using diastereopeptides to control metal ion coordination in proteins. Proc Natl Acad Sci U S A (2008) 1.06
The interaction of mitochondrial iron with manganese superoxide dismutase. J Biol Chem (2009) 1.06
Site-selective metal binding by designed alpha-helical peptides. J Am Chem Soc (2005) 1.05
Coencapsulation of arsenic- and platinum-based drugs for targeted cancer treatment. Angew Chem Int Ed Engl (2009) 1.04
Hg(II) binding to a weakly associated coiled coil nucleates an encoded metalloprotein fold: a kinetic analysis. Proc Natl Acad Sci U S A (2003) 1.02
Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides. Dalton Trans (2009) 1.02
The correlation of 113Cd NMR and 111mCd PAC spectroscopies provides a powerful approach for the characterization of the structure of Cd(II)-substituted Zn(II) proteins. Chemistry (2009) 1.01
Control of metal coordination number in de novo designed peptides through subtle sequence modifications. J Am Chem Soc (2004) 1.00
XANES evidence against a manganyl species in the S3 state of the oxygen-evolving complex. J Am Chem Soc (2004) 0.99
Structural characterization of the zinc site in protein farnesyltransferase. J Am Chem Soc (2003) 0.99
Switching the chirality of the metal environment alters the coordination mode in designed peptides. Angew Chem Int Ed Engl (2009) 0.99
An atypical linear Cu(I)-S2 center constitutes the high-affinity metal-sensing site in the CueR metalloregulatory protein. J Am Chem Soc (2003) 0.98
Structural comparisons of apo- and metalated three-stranded coiled coils clarify metal binding determinants in thiolate containing designed peptides. J Am Chem Soc (2010) 0.98
EXAFS studies of the zinc sites of UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). J Inorg Biochem (2003) 0.95
Probing a homoleptic PbS3 coordination environment in a designed peptide using 207Pb NMR spectroscopy: implications for understanding the molecular basis of lead toxicity. Angew Chem Int Ed Engl (2010) 0.95
pH-dependent structures of the manganese binding sites in oxalate decarboxylase as revealed by high-field electron paramagnetic resonance. J Phys Chem B (2009) 0.95
Experimental and computational X-ray emission spectroscopy as a direct probe of protonation states in oxo-bridged Mn(IV) dimers relevant to redox-active metalloproteins. Inorg Chem (2013) 0.94
Design of thiolate rich metal binding sites within a peptidic framework. Inorg Chem (2008) 0.93
Controllable formation of heterotrimetallic coordination compounds: systematically incorporating lanthanide and alkali metal ions into the manganese 12-metallacrown-4 framework. Inorg Chem (2014) 0.93
Controlling and fine tuning the physical properties of two identical metal coordination sites in de novo designed three stranded coiled coil peptides. J Am Chem Soc (2010) 0.92
Influence of active site location on catalytic activity in de novo-designed zinc metalloenzymes. J Am Chem Soc (2013) 0.91
Designing hydrolytic zinc metalloenzymes. Biochemistry (2014) 0.91
Ternary complexes of gentamicin with iron and lipid catalyze formation of reactive oxygen species. Chem Res Toxicol (2005) 0.91
Design of a three-helix bundle capable of binding heavy metals in a triscysteine environment. Angew Chem Int Ed Engl (2011) 0.91
Assembly of near-infrared luminescent lanthanide host(host-guest) complexes with a metallacrown sandwich motif. Angew Chem Int Ed Engl (2011) 0.90
Isolation of elusive tetranuclear and pentanuclear M(II)-hydroximate intermediates in the assembly of lanthanide [15-metallacrown-5] complexes. Inorg Chem (2013) 0.89
Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α3DIV, that Sequesters Toxic Heavy Metals. Biochemistry (2015) 0.87
Electronic structural changes of Mn in the oxygen-evolving complex of photosystem II during the catalytic cycle. Inorg Chem (2013) 0.87
A de novo designed metalloenzyme for the hydration of CO2. Angew Chem Int Ed Engl (2014) 0.87
The importance of stereochemically active lone pairs for influencing Pb(II) and As(III) protein binding. Chemistry (2012) 0.87
The protonation states of oxo-bridged Mn(IV) dimers resolved by experimental and computational Mn K pre-edge X-ray absorption spectroscopy. Inorg Chem (2013) 0.87
Multinuclear Fe(III) complexes with polydentate ligands of the family of dicarboxyimidazoles: nuclearity- and topology-controlled syntheses and Magneto-structural correlations. Inorg Chem (2005) 0.87
De novo-designed metallopeptides with type 2 copper centers: modulation of reduction potentials and nitrite reductase activities. J Am Chem Soc (2013) 0.85
Pb-207 NMR spectroscopy reveals that Pb(II) coordinates with glutathione (GSH) and tris cysteine zinc finger proteins in a PbS3 coordination environment. J Inorg Biochem (2011) 0.85
Highly emitting near-infrared lanthanide "encapsulated sandwich" metallacrown complexes with excitation shifted toward lower energy. J Am Chem Soc (2014) 0.85
Reactivity of peroxo forms of the vanadium haloperoxidase cofactor. A DFT investigation. J Am Chem Soc (2005) 0.85
Preparation of resolved fourfold symmetric amphiphilic helices using chiral metallacrown building blocks. Angew Chem Int Ed Engl (2002) 0.84
Solution chemistry of copper(II)-gentamicin complexes: relevance to metal-related aminoglycoside toxicity. Inorg Chem (2003) 0.83
Activation of Escherichia coli UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase by Fe2+ yields a more efficient enzyme with altered ligand affinity. Biochemistry (2010) 0.83
Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution. Chemistry (2013) 0.82
Metalloprotein folding. Inorg Chem (2004) 0.82
Solvent dependent assembly of lanthanide metallacrowns using building blocks with incompatible symmetry preferences. Inorg Chem (2014) 0.81
Gd(III)[15-metallacrown-5] recognition of chiral α-amino acid analogues. Inorg Chem (2011) 0.81
Heavy-metal complexation by de novo peptide design. Curr Opin Drug Discov Devel (2002) 0.81
Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide. Chem Commun (Camb) (2013) 0.81
De Novo Design and Characterization of Copper Metallopeptides Inspired by Native Cupredoxins. Inorg Chem (2015) 0.81
Reevaluation of the kinetics of polynuclear mimics for manganese catalases. Inorg Chem (2007) 0.80
Structural and physical characterization of tetranuclear [Mn(II)3Mn(IV)] and [Mn(II)2Mn(III)2] valence-isomer manganese complexes. Inorg Chem (2008) 0.80
Insight into the catalytic mechanism of vanadium haloperoxidases. DFT investigation of vanadium cofactor reactivity. Inorg Chem (2006) 0.80
The relationship between the manganese(II) zero-field interaction and Mn(II)/Mn(III) redox potential of Mn(4'-X-terpy)2 complexes. J Am Chem Soc (2007) 0.80
The first spectroscopic model for the S1 state multiline signal of the OEC. Biochim Biophys Acta (2004) 0.80
Experimental and theoretical evaluation of multisite cadmium(II) exchange in designed three-stranded coiled-coil peptides. J Am Chem Soc (2012) 0.79
Structure and dynamics of metalloproteins in live cells. Methods Cell Biol (2008) 0.79
Evaluating hydrogen bond interactions in enzymes containing Mn(III)-histidine complexation using manganese-imidazole complexes. J Biol Inorg Chem (2002) 0.79
Synthesis, structure, and magnetic properties of a large lanthanide-transition-metal single-molecule magnet. Angew Chem Int Ed Engl (2004) 0.79
Models for the lower S states of photosystem II: a trinuclear mixed-valent MnII/MnIV/MnII complex. Inorg Chem (2003) 0.78
Tuning the redox properties of manganese(II) and its implications to the electrochemistry of manganese and iron superoxide dismutases. Inorg Chem (2008) 0.78
Assessing the dependence of (51)V A(z) value on the aromatic ring orientation of V(IV)O(2+) pyridine complexes. Inorg Chem (2009) 0.78