Published in Angew Chem Int Ed Engl on January 01, 2009
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Hydrolytic catalysis and structural stabilization in a designed metalloprotein. Nat Chem (2011) 1.37
Isolation of the first ferromagnetically coupled Mn(III/IV) complex. Chem Commun (Camb) (2003) 1.33
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Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils. Proc Natl Acad Sci U S A (2007) 1.19
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Reflections on Small Molecule Manganese Models that Seek to Mimic Photosynthetic Water Oxidation Chemistry. Coord Chem Rev (2008) 1.18
Protein design: toward functional metalloenzymes. Chem Rev (2014) 1.17
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Structure-based design, synthesis, evaluation, and crystallographic studies of conformationally constrained Smac mimetics as inhibitors of the X-linked inhibitor of apoptosis protein (XIAP). J Med Chem (2008) 1.11
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Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils. Angew Chem Int Ed Engl (2006) 1.09
Synthesis and magnetic properties of a metallacryptate that behaves as a single-molecule magnet. Angew Chem Int Ed Engl (2003) 1.08
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Heterochromia in designed metallopeptides: geometry-selective binding of CdII in a de novo peptide. Angew Chem Int Ed Engl (2007) 1.07
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Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold. J Med Chem (2012) 1.06
Site-selective metal binding by designed alpha-helical peptides. J Am Chem Soc (2005) 1.05
Crystal structure of banana lectin reveals a novel second sugar binding site. Glycobiology (2005) 1.03
Hg(II) binding to a weakly associated coiled coil nucleates an encoded metalloprotein fold: a kinetic analysis. Proc Natl Acad Sci U S A (2003) 1.02
Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides. Dalton Trans (2009) 1.02
CSAR data set release 2012: ligands, affinities, complexes, and docking decoys. J Chem Inf Model (2013) 1.02
The correlation of 113Cd NMR and 111mCd PAC spectroscopies provides a powerful approach for the characterization of the structure of Cd(II)-substituted Zn(II) proteins. Chemistry (2009) 1.01
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Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence. Mol Microbiol (2005) 1.00
Control of metal coordination number in de novo designed peptides through subtle sequence modifications. J Am Chem Soc (2004) 1.00
Designing a functional type 2 copper center that has nitrite reductase activity within α-helical coiled coils. Proc Natl Acad Sci U S A (2012) 0.99
XANES evidence against a manganyl species in the S3 state of the oxygen-evolving complex. J Am Chem Soc (2004) 0.99
Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades. J Biol Chem (2002) 0.98
Structural comparisons of apo- and metalated three-stranded coiled coils clarify metal binding determinants in thiolate containing designed peptides. J Am Chem Soc (2010) 0.98
Ordering a dynamic protein via a small-molecule stabilizer. J Am Chem Soc (2013) 0.97
3-Substituted-N-(4-hydroxynaphthalen-1-yl)arylsulfonamides as a novel class of selective Mcl-1 inhibitors: structure-based design, synthesis, SAR, and biological evaluation. J Med Chem (2014) 0.96
Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains. Anal Biochem (2007) 0.96
Laboratory evolution of one disulfide isomerase to resemble another. Proc Natl Acad Sci U S A (2007) 0.95
Probing a homoleptic PbS3 coordination environment in a designed peptide using 207Pb NMR spectroscopy: implications for understanding the molecular basis of lead toxicity. Angew Chem Int Ed Engl (2010) 0.95
pH-dependent structures of the manganese binding sites in oxalate decarboxylase as revealed by high-field electron paramagnetic resonance. J Phys Chem B (2009) 0.95
Experimental and computational X-ray emission spectroscopy as a direct probe of protonation states in oxo-bridged Mn(IV) dimers relevant to redox-active metalloproteins. Inorg Chem (2013) 0.94
Controllable formation of heterotrimetallic coordination compounds: systematically incorporating lanthanide and alkali metal ions into the manganese 12-metallacrown-4 framework. Inorg Chem (2014) 0.93
Design of thiolate rich metal binding sites within a peptidic framework. Inorg Chem (2008) 0.93
Structural bases for the different anti-fibrillatory effects of chloroquine and quinidine. Cardiovasc Res (2011) 0.93
Controlling and fine tuning the physical properties of two identical metal coordination sites in de novo designed three stranded coiled coil peptides. J Am Chem Soc (2010) 0.92
Influence of active site location on catalytic activity in de novo-designed zinc metalloenzymes. J Am Chem Soc (2013) 0.91
Designing hydrolytic zinc metalloenzymes. Biochemistry (2014) 0.91
Interaction of a cyclic, bivalent smac mimetic with the x-linked inhibitor of apoptosis protein. Biochemistry (2008) 0.91
Design of a three-helix bundle capable of binding heavy metals in a triscysteine environment. Angew Chem Int Ed Engl (2011) 0.91
Ternary complexes of gentamicin with iron and lipid catalyze formation of reactive oxygen species. Chem Res Toxicol (2005) 0.91
Assembly of near-infrared luminescent lanthanide host(host-guest) complexes with a metallacrown sandwich motif. Angew Chem Int Ed Engl (2011) 0.90
Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression. J Med Chem (2012) 0.89
Isolation of elusive tetranuclear and pentanuclear M(II)-hydroximate intermediates in the assembly of lanthanide [15-metallacrown-5] complexes. Inorg Chem (2013) 0.89
Structural basis for the enhanced stability of highly fluorinated proteins. Proc Natl Acad Sci U S A (2012) 0.88
The tail of KdsC: conformational changes control the activity of a haloacid dehalogenase superfamily phosphatase. J Biol Chem (2009) 0.88
Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α3DIV, that Sequesters Toxic Heavy Metals. Biochemistry (2015) 0.87
Multinuclear Fe(III) complexes with polydentate ligands of the family of dicarboxyimidazoles: nuclearity- and topology-controlled syntheses and Magneto-structural correlations. Inorg Chem (2005) 0.87
The protonation states of oxo-bridged Mn(IV) dimers resolved by experimental and computational Mn K pre-edge X-ray absorption spectroscopy. Inorg Chem (2013) 0.87
Electronic structural changes of Mn in the oxygen-evolving complex of photosystem II during the catalytic cycle. Inorg Chem (2013) 0.87
Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity. Mol Endocrinol (2010) 0.87
The importance of stereochemically active lone pairs for influencing Pb(II) and As(III) protein binding. Chemistry (2012) 0.87
A de novo designed metalloenzyme for the hydration of CO2. Angew Chem Int Ed Engl (2014) 0.87
Conserved residues in the HAMP domain define a new family of proposed bipartite energy taxis receptors. J Bacteriol (2008) 0.86
Modeling the tertiary structure of the patatin domain of neuropathy target esterase. Protein J (2007) 0.85
De novo-designed metallopeptides with type 2 copper centers: modulation of reduction potentials and nitrite reductase activities. J Am Chem Soc (2013) 0.85
Structure-based design of potent Bcl-2/Bcl-xL inhibitors with strong in vivo antitumor activity. J Med Chem (2012) 0.85
Pb-207 NMR spectroscopy reveals that Pb(II) coordinates with glutathione (GSH) and tris cysteine zinc finger proteins in a PbS3 coordination environment. J Inorg Biochem (2011) 0.85
Highly emitting near-infrared lanthanide "encapsulated sandwich" metallacrown complexes with excitation shifted toward lower energy. J Am Chem Soc (2014) 0.85
Reactivity of peroxo forms of the vanadium haloperoxidase cofactor. A DFT investigation. J Am Chem Soc (2005) 0.85
Preparation of resolved fourfold symmetric amphiphilic helices using chiral metallacrown building blocks. Angew Chem Int Ed Engl (2002) 0.84
Solution chemistry of copper(II)-gentamicin complexes: relevance to metal-related aminoglycoside toxicity. Inorg Chem (2003) 0.83
Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution. Chemistry (2013) 0.82
Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc Natl Acad Sci U S A (2013) 0.82
Metalloprotein folding. Inorg Chem (2004) 0.82
Heavy-metal complexation by de novo peptide design. Curr Opin Drug Discov Devel (2002) 0.81
Solvent dependent assembly of lanthanide metallacrowns using building blocks with incompatible symmetry preferences. Inorg Chem (2014) 0.81
Gd(III)[15-metallacrown-5] recognition of chiral α-amino acid analogues. Inorg Chem (2011) 0.81
De Novo Design and Characterization of Copper Metallopeptides Inspired by Native Cupredoxins. Inorg Chem (2015) 0.81
Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity. ACS Chem Biol (2016) 0.81
Insight into the catalytic mechanism of vanadium haloperoxidases. DFT investigation of vanadium cofactor reactivity. Inorg Chem (2006) 0.80
The relationship between the manganese(II) zero-field interaction and Mn(II)/Mn(III) redox potential of Mn(4'-X-terpy)2 complexes. J Am Chem Soc (2007) 0.80
A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions. Assay Drug Dev Technol (2011) 0.80
The first spectroscopic model for the S1 state multiline signal of the OEC. Biochim Biophys Acta (2004) 0.80
Reevaluation of the kinetics of polynuclear mimics for manganese catalases. Inorg Chem (2007) 0.80
Structural and physical characterization of tetranuclear [Mn(II)3Mn(IV)] and [Mn(II)2Mn(III)2] valence-isomer manganese complexes. Inorg Chem (2008) 0.80