Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the Intensive Care Unit: executive summary.

Implementing the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle into everyday care: opportunities, challenges, and lessons learned for implementing the ICU Pain, Agitation, and Delirium Guidelines. Crit Care Med (2013) 1.28

Preventing delirium in the intensive care unit. Crit Care Clin (2013) 0.96

A Physiologically Based Pharmacokinetic Modeling Approach to Predict Buprenorphine Pharmacokinetics following Intravenous & Sublingual Administration. Br J Clin Pharmacol (2017) 0.79

Clinical practice guidelines for delirium management: potential application in palliative care. J Pain Symptom Manage (2014) 0.79

Quality of clinical practice guidelines in delirium: a systematic appraisal. BMJ Open (2017) 0.79

Identification of acute brain failure using electronic medical records. J Crit Care (2016) 0.75

Screening and Management of Delirium in Critically Ill Patients. Hosp Pharm (2015) 0.75

Incidence and risk factors of delirium in multi-center Thai surgical intensive care units: a prospective cohort study. J Intensive Care (2015) 0.75

Addition of dexmedetomidine to benzodiazepines for patients with alcohol withdrawal syndrome in the intensive care unit: a randomized controlled study. Ann Intensive Care (2015) 0.75

Seeking to humanize intensive care. Rev Bras Ter Intensiva (2017) 0.75

Evaluating physical functioning in critical care: considerations for clinical practice and research. Crit Care (2017) 0.75

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med (2013) 39.56

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57

Grading quality of evidence and strength of recommendations. BMJ (2004) 26.08

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med (2013) 17.37

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell (2006) 11.79

GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol (2010) 11.77

Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet (2009) 11.72

Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med (2013) 11.44

Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA (2010) 10.82

Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA (2009) 10.24

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet (2008) 10.13

Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med (2002) 9.74

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33

Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA (2007) 7.74

Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. JAMA (2012) 6.69

Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr (2009) 6.54

Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA (2008) 6.39

Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). JAMA (2003) 6.24

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med (2008) 5.30

An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations. Am J Respir Crit Care Med (2006) 5.29

Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ (2008) 5.16

Practice guidelines for central venous access: a report by the American Society of Anesthesiologists Task Force on Central Venous Access. Anesthesiology (2012) 4.97

Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis (2001) 4.94

Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82

Costs associated with delirium in mechanically ventilated patients. Crit Care Med (2004) 4.75

Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med (2010) 4.69

Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit. Am J Respir Crit Care Med (2014) 4.54

Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive Care Med (2013) 4.37

Delirium in the cardiovascular ICU: exploring modifiable risk factors. Crit Care Med (2013) 4.34

Clinical practice guidelines for support of the family in the patient-centered intensive care unit: American College of Critical Care Medicine Task Force 2004-2005. Crit Care Med (2007) 4.14

Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med (2003) 4.04

Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology (2006) 4.03

Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96

The Future of Anesthesiology: Should the Perioperative Surgical Home Redefine Us? Anesth Analg (2015) 3.84

Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest (2001) 3.77

Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America. Crit Care Med (2008) 3.67

GRADE guidelines 6. Rating the quality of evidence--imprecision. J Clin Epidemiol (2011) 3.54

Guidelines for the inter- and intrahospital transport of critically ill patients. Crit Care Med (2004) 3.53

A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients. Crit Care Med (2006) 3.49

Weaning patients from the ventilator. N Engl J Med (2012) 3.49

The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med (2010) 3.47

Chlorhexidine, toothbrushing, and preventing ventilator-associated pneumonia in critically ill adults. Am J Crit Care (2009) 3.47

Effectiveness and safety of the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle. Crit Care Med (2014) 3.46

Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients. Intensive Care Med (2012) 3.39

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med (2014) 3.37

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis. Oncogene (2003) 3.37

Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med (2010) 3.32

GRADE guidelines: 9. Rating up the quality of evidence. J Clin Epidemiol (2011) 3.30

Validity of composite end points in clinical trials. BMJ (2005) 3.26

A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab (2003) 3.25

Intensive care unit quality improvement: a "how-to" guide for the interdisciplinary team. Crit Care Med (2006) 3.15

Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ (2007) 3.06

A readers' guide to the interpretation of diagnostic test properties: clinical example of sepsis. Intensive Care Med (2003) 3.06

Preoperative clinic visits reduce operating room cancellations and delays. Anesthesiology (2005) 3.03

GRADE guidelines: 7. Rating the quality of evidence--inconsistency. J Clin Epidemiol (2011) 3.02

Immortal time bias in critical care research: application of time-varying Cox regression for observational cohort studies. Crit Care Med (2009) 2.96

Efficacy and safety of quetiapine in critically ill patients with delirium: a prospective, multicenter, randomized, double-blind, placebo-controlled pilot study. Crit Care Med (2010) 2.92

Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system. BMC Health Serv Res (2005) 2.91

Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. Crit Care Med (2010) 2.86

Six-month neuropsychological outcome of medical intensive care unit patients. Crit Care Med (2003) 2.83

GRADE guidelines: 8. Rating the quality of evidence--indirectness. J Clin Epidemiol (2011) 2.83

Pay for performance in critical care: an executive summary of the position paper by the Society of Critical Care Medicine. Crit Care Med (2009) 2.78

Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med (2009) 2.77

Findings on the portable chest radiograph correlate with fluid balance in critically ill patients. Chest (2002) 2.77

Dexmedetomidine: an updated review. Ann Pharmacother (2007) 2.77

Acute kidney injury and cardiovascular outcomes in acute severe hypertension. Circulation (2010) 2.76

Neurologic outcomes and postresuscitation care of patients with myoclonus following cardiac arrest. Crit Care Med (2015) 2.75

Large-scale implementation of sedation and delirium monitoring in the intensive care unit: a report from two medical centers. Crit Care Med (2005) 2.72

The association between delirium and cognitive decline: a review of the empirical literature. Neuropsychol Rev (2004) 2.72

Feasibility of physical and occupational therapy beginning from initiation of mechanical ventilation. Crit Care Med (2010) 2.71

Predictors of reintubation in critically ill patients. Respir Care (2013) 2.71

Care of the potential organ donor. N Engl J Med (2004) 2.66

Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit. Crit Care Med (2011) 2.59