Published in Org Lett on December 26, 2012
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Synthesis of the deoxyaminosugar (+)-D-forosamine via a novel domino-Knoevenagel-hetero-Diels-Alder reaction. Org Lett (2009) 0.77
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Efficient and versatile synthesis of indoles from enamines and imines by cross-dehydrogenative coupling. Angew Chem Int Ed Engl (2012) 0.77
The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: synthesis, structure and bioactivity of isocyalexin A. Org Biomol Chem (2012) 0.77
Immobilized alpha-diazophosphonoacetate as a versatile key precursor for palladium catalyzed indole synthesis on a polymer support. Chem Commun (Camb) (2002) 0.76
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell (2008) 5.67
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology (2008) 2.05
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Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol (2005) 1.47
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Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun (2006) 1.41
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Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. J Med Chem (2011) 1.25
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Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. J Immunol (2007) 1.12
An oxazolo[3,2-b]indazole route to 1H-indazolones. Org Lett (2009) 1.12
Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Mol Pharmacol (2011) 1.07
Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells. Free Radic Biol Med (2008) 1.05
Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. J Med Chem (2010) 1.04
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. Am J Physiol Lung Cell Mol Physiol (2003) 1.03
A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular Bis-heterocyclizations. J Org Chem (2007) 1.01
N,N-bond-forming heterocyclization: synthesis of 3-alkoxy-2H-indazoles. J Org Chem (2006) 0.98
The Davis-Beirut reaction: N1,N2-disubstituted-1H-indazolones via 1,6-electrophilic addition to 3-alkoxy-2H-indazoles. Org Lett (2011) 0.97
Synthesis of a library of 2-alkyl-3-alkyloxy-2H-indazole-6-carboxamides. J Comb Chem (2007) 0.96
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Nucleophilic substitution of oxazino-/oxazolino-/benzoxazin [3,2-b]indazoles: an effective route to 1H-indazolones. Org Lett (2010) 0.96
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A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. J Comb Chem (2007) 0.95
Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorg Med Chem Lett (2009) 0.95
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Efficient syntheses of the unknown quinolino[2,3-c]cinnolines; synthesis of neocryptolepines. Org Lett (2010) 0.88
Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis? Trends Mol Med (2012) 0.88
Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to gamma-butyrolactones. J Org Chem (2002) 0.87
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Synthesis of spiro-fused pyrazolidoylisoxazolines. J Org Chem (2011) 0.87
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Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin. J Med Chem (2009) 0.83
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Multicomponent assembly of highly substituted indoles by dual palladium-catalyzed coupling reactions. Angew Chem Int Ed Engl (2012) 0.82
Isoxazolopyrimidines as Novel ΔF508-CFTR Correctors. Synlett (2010) 0.82
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Functional fluorescently labeled bithiazole ΔF508-CFTR corrector imaged in whole body slices in mice. Bioconjug Chem (2011) 0.80
Multicomponent macrocyclization reactions (MCMRs) employing highly reactive acyl ketene and nitrile oxide intermediates. Org Lett (2011) 0.80
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Versatile "traceless" sulfone linker for SPOS: preparation of isoxazolinopyrrole 2-carboxylates. J Org Chem (2002) 0.80
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Expedient synthesis of a 72-membered isoxazolino-β-ketoamide library by a 2·3-component reaction. ACS Comb Sci (2012) 0.78
Acid and base catalyzed Davis-Beirut reaction: experimental and theoretical mechanistic studies and synthesis of novel 3-amino-2H-indazoles. Tetrahedron Lett (2012) 0.78
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Activation of CFTR by UCCF-029 and genistein. Bioorg Med Chem Lett (2008) 0.76
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. Bioorg Med Chem Lett (2012) 0.76
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Synthesis of substituted chromanones: an organocatalytic aldol/oxa-Michael reaction. Org Lett (2010) 0.75
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On-bead combinatorial techniques for the identification of selective aldose reductase inhibitors. Bioorg Med Chem (2006) 0.75
Correction to "Diverting Reactive Intermediates Toward Unusual Chemistry: Unexpected Anthranil Products from Davis-Beirut Reaction". J Org Chem (2017) 0.75
Imidazopyridinium and pyridopyrimidium bromides: synthesis and hydrolysis. J Org Chem (2002) 0.75
Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives. J Org Chem (2002) 0.75
The sulfone linker in solid-phase synthesis: preparation of 3,5-disubstituted cyclopent-2-enones. J Org Chem (2002) 0.75
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