Published in Int J Epidemiol on December 01, 2012
Atomic data: James Mackenzie Lecture 2015. Br J Gen Pract (2016) 0.82
Lessons from Mackenzie that still resonate. Br J Gen Pract (2013) 0.75
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science (2007) 32.97
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet (2012) 20.09
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Metformin and reduced risk of cancer in diabetic patients. BMJ (2005) 13.04
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Designing and evaluating complex interventions to improve health care. BMJ (2007) 9.78
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet (2007) 6.87
Early treatment with prednisolone or acyclovir in Bell's palsy. N Engl J Med (2007) 6.85
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care (2009) 6.17
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat Genet (2008) 5.93
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Diabetes (2008) 4.57
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use. Diabetes Care (2003) 4.23
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
NeuPSIG guidelines on neuropathic pain assessment. Pain (2010) 4.04
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes (2008) 3.76
The epidemiology of chronic pain of predominantly neuropathic origin. Results from a general population survey. J Pain (2006) 3.67
Common variants in WFS1 confer risk of type 2 diabetes. Nat Genet (2007) 3.58
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Process evaluations for cluster-randomised trials of complex interventions: a proposed framework for design and reporting. Trials (2013) 2.77
Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis. BMJ Open (2013) 2.59
The S-LANSS score for identifying pain of predominantly neuropathic origin: validation for use in clinical and postal research. J Pain (2005) 2.37
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet (2012) 2.34
Biomedicine, holism and general medical practice: responses to the 2004 General Practitioner contract. Sociol Health Illn (2008) 2.28
Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity. Age Ageing (2012) 2.26
Multimorbidity and the inverse care law in primary care. BMJ (2012) 2.26
Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability. BMC Med Genet (2006) 2.25
Managing patients with mental and physical multimorbidity. BMJ (2012) 2.08
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function. Am J Respir Crit Care Med (2011) 2.07
Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes (2007) 2.03
Screening for and treating left-ventricular abnormalities in diabetes mellitus: a new way of reducing cardiac deaths. Lancet (2002) 1.89
A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One (2012) 1.72
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med (2013) 1.70
Risk of cardiovascular disease and total mortality in adults with type 1 diabetes: Scottish registry linkage study. PLoS Med (2012) 1.69
Cohort Profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness. Int J Epidemiol (2012) 1.67
Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Diabetes (2008) 1.64
e-Prescribing, efficiency, quality: lessons from the computerization of UK family practice. J Am Med Inform Assoc (2006) 1.61
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet (2009) 1.61
Assessing change in chronic pain severity: the chronic pain grade compared with retrospective perceptions. Br J Gen Pract (2002) 1.60
Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol (2009) 1.60
Depression and multimorbidity: a cross-sectional study of 1,751,841 patients in primary care. J Clin Psychiatry (2014) 1.59
An 'endless struggle': a qualitative study of general practitioners' and practice nurses' experiences of managing multimorbidity in socio-economically deprived areas of Scotland. Chronic Illn (2010) 1.54
Effect of Metformin on mortality in patients with heart failure and type 2 diabetes mellitus. Am J Cardiol (2010) 1.50
No differences in mortality between users of pancreatic-specific and non-pancreatic-specific sulphonylureas: a cohort analysis. Diabetes Obes Metab (2007) 1.50
Long-acting β-agonist prescribing in people with asthma in primary care. Thorax (2012) 1.48
A randomized controlled trial of spiritual healing in restricted neck movement. J Altern Complement Med (2003) 1.45
World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain? Pain (2015) 1.44
Severe chronic pain is associated with increased 10 year mortality. A cohort record linkage study. Eur J Pain (2009) 1.42
Bell's palsy: new evidence provides a definitive drug therapy strategy. Br J Gen Pract (2009) 1.38
Serum thyroid-stimulating hormone concentration and morbidity from cardiovascular disease and fractures in patients on long-term thyroxine therapy. J Clin Endocrinol Metab (2009) 1.36
Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: a GoDARTS study. Diabetes (2009) 1.34
Development and validation of a model for predicting emergency admissions over the next year (PEONY): a UK historical cohort study. Arch Intern Med (2008) 1.34
Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia. Malar J (2010) 1.31
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol (2013) 1.30
Locality deprivation and Type 2 diabetes incidence: a local test of relative inequalities. Soc Sci Med (2007) 1.30
Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance. Diabetes (2011) 1.29
Double trouble: the impact of multimorbidity and deprivation on preference-weighted health related quality of life a cross sectional analysis of the Scottish Health Survey. Int J Equity Health (2013) 1.28
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study. Arterioscler Thromb Vasc Biol (2004) 1.26
Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group. Diabetes Care (2011) 1.26
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes (2013) 1.25
Metformin in cancer treatment and prevention. Annu Rev Med (2014) 1.23
Quality and safety of medication use in primary care: consensus validation of a new set of explicit medication assessment criteria and prioritisation of topics for improvement. BMC Clin Pharmacol (2012) 1.22
Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). Invest Ophthalmol Vis Sci (2011) 1.22
Record rewards: the effects of targeted quality incentives on the recording of risk factors by primary care providers. Health Econ (2010) 1.20
Practice postcode versus patient population: a comparison of data sources in England and Scotland. Int J Health Geogr (2008) 1.20
Interventions for impetigo. Cochrane Database Syst Rev (2012) 1.19
A managed clinical network for cardiac services: set-up, operation and impact on patient care. Int J Integr Care (2005) 1.19
A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study. Pharmacogenet Genomics (2008) 1.19
Schizophrenia is associated with excess multiple physical-health comorbidities but low levels of recorded cardiovascular disease in primary care: cross-sectional study. BMJ Open (2013) 1.18
Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study. Pharmacogenet Genomics (2008) 1.18
Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial. BMJ Open (2013) 1.16
Assessment of neuropathic pain in primary care. Am J Med (2009) 1.14
Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: a nationwide study. Diabetes Care (2012) 1.14
Early experience of the use of short message service (SMS) technology in routine clinical care. Inform Prim Care (2008) 1.14
Trends in primary care antidepressant prescribing 1995-2007: a longitudinal population database analysis. Br J Gen Pract (2011) 1.13
Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study. Circulation (2005) 1.13
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis (2012) 1.13
Neuropathic pain in the community: more under-treated than refractory? Pain (2013) 1.10
Can pain can be more or less neuropathic? Comparison of symptom assessment tools with ratings of certainty by clinicians. Pain (2006) 1.10