Published in PLoS One on December 28, 2012
Analysis of canonical and non-canonical splice sites in mammalian genomes. Nucleic Acids Res (2000) 4.29
Mechanisms initiating platelet thrombus formation. Thromb Haemost (1997) 2.73
Bernard-Soulier syndrome. Blood (1998) 2.29
Signaling events underlying thrombus formation. J Thromb Haemost (2003) 2.07
Central role of the P2Y12 receptor in platelet activation. J Clin Invest (2004) 1.96
Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome. Proc Natl Acad Sci U S A (2000) 1.94
Platelet membrane glycoproteins implicated in ristocetin-induced aggregation. Studies of the proteins on platelets from patients with Bernard-Soulier syndrome and von Willebrand's disease. J Clin Invest (1976) 1.67
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress. J Clin Invest (1991) 1.66
Modified thromboelastography evaluation of platelet dysfunction in patients undergoing coronary artery surgery. Eur J Cardiothorac Surg (2010) 1.57
Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg (2012) 1.54
Postinjury coagulopathy management: goal directed resuscitation via POC thrombelastography. Ann Surg (2010) 1.51
Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma. J Am Coll Surg (2012) 1.35
High dose factor VIIa improves clot structure and stability in a model of haemophilia B. Br J Haematol (2005) 1.27
Signaling through G proteins in platelets: to the integrins and beyond. Thromb Haemost (1997) 1.22
Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic risk. Blood (2002) 1.20
A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia. Blood (1987) 1.17
Influence of Ca2+ on the structure of reptilase-derived and thrombin-derived fibrin gels. Biochem J (1986) 1.14
Platelet adhesion to collagen. Thromb Res (2011) 1.04
Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography. J Extra Corpor Technol (2011) 1.02
The predictive value of modified computerized thromboelastography and platelet function analysis for postoperative blood loss in routine cardiac surgery. Anesth Analg (2003) 1.02
Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications. J Biol Chem (1992) 1.01
Comparison of early platelet activation in patients undergoing on-pump versus off-pump coronary artery bypass surgery. J Thorac Cardiovasc Surg (2007) 0.99
Platelet dysfunction is an early marker for traumatic brain injury-induced coagulopathy. Neurocrit Care (2013) 0.96
NH2-terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens. J Clin Invest (1992) 0.91
Naturally occurring mutations in glycoprotein Ibalpha that result in defective ligand binding and synthesis of a truncated protein. Blood (1998) 0.91
Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg (1994) 0.91
Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI. Biochem Biophys Res Commun (2000) 0.90
Shear-induced interaction of platelets with von Willebrand factor results in glycoprotein Ibalpha shedding. Am J Physiol Heart Circ Physiol (2009) 0.89
A dinucleotide deletion results in defective membrane anchoring and circulating soluble glycoprotein Ib alpha in a novel form of Bernard-Soulier syndrome. Blood (1997) 0.88
Coagulation monitoring of the bleeding traumatized patient. Curr Opin Anaesthesiol (2012) 0.86
Bernard-Soulier syndrome caused by a dinucleotide deletion and reading frameshift in the region encoding the glycoprotein Ib alpha transmembrane domain. Blood (1997) 0.83
An accompanying genetic severe deficiency of tissue factor protects mice with a protein C deficiency from lethal endotoxemia. Blood (2010) 0.81
Increases in circulating levels of monocyte-platelet and neutrophil-platelet complexes following hip arthroplasty. Clin Sci (Lond) (2002) 0.80
Systematic screening for genetic polymorphism in human platelet glycoprotein Ibalpha. Immunogenetics (1996) 0.80
Disappearance of glycoprotein Ib from the platelet surface in pericardial blood during cardiopulmonary bypass. J Thorac Cardiovasc Surg (1998) 0.79
Molecular biological identification and characterization of inherited platelet receptor disorders. Methods Mol Med (1999) 0.77
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci U S A (2005) 2.46
Acute liver failure induced by green tea extracts: case report and review of the literature. Liver Transpl (2006) 2.13
Structure and function of the plasminogen/plasmin system. Thromb Haemost (2005) 2.02
Cardiovascular disease in US firefighters: a systematic review. Cardiol Rev (2011) 1.86
Management of "buried" penis in adulthood: an overview. Plast Reconstr Surg (2009) 1.69
Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture. Blood (2009) 1.59
Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med (2007) 1.53
A missense mutation in the sodium phosphate co-transporter Slc34a1 impairs phosphate homeostasis. J Am Soc Nephrol (2008) 1.51
Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization. Stem Cells (2007) 1.45
Emergency physician survey: recombinant tissue plasminogen activator for stroke. Ann Emerg Med (2006) 1.39
Rapid selection of Drosophila S2 cells with the puromycin resistance gene. Biotechniques (2003) 1.35
Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma. J Am Coll Surg (2012) 1.35
Transcriptional profiling of the transition from normal intestinal epithelia to adenomas and carcinomas in the APCMin/+ mouse. Physiol Genomics (2003) 1.26
Cannabinoid hyperemesis and compulsive bathing: a case series and paradoxical pathophysiological explanation. J Am Board Fam Med (2010) 1.25
Evidence-based approach to cholangiocarcinoma: a systematic review of the current literature. J Am Coll Surg (2008) 1.25
Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge. Thromb Haemost (2002) 1.23
Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities. J Clin Invest (2005) 1.17
Regulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97). J Biol Chem (2002) 1.12
Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1-deficient mice. J Biol Chem (2003) 1.08
A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells. J Biol Chem (2006) 1.05
Thrombospondin 1--a regulator of adenoma growth and carcinoma progression in the APC(Min/+) mouse model. Carcinogenesis (2003) 1.04
Plasminogen activator inhibitor-1: the double-edged sword in apoptosis. Thromb Haemost (2008) 1.03
Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells. Cancer Lett (2010) 1.03
Conservation of critical functional domains in murine plasminogen activator inhibitor-1. J Biol Chem (2004) 1.02
Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol (2009) 1.01
Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination. J Biomed Biotechnol (2012) 1.01
Generation of genetically-altered mice producing very low levels of coagulation factorVII. Thromb Haemost (2005) 1.00
Three new Nudix hydrolases from Escherichia coli. J Biol Chem (2006) 0.98
Aspiration of radiolucent dentures in facial trauma: Case report. Ear Nose Throat J (2010) 0.97
Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse. Am J Pathol (2002) 0.96
Unexpected role of anticoagulant protein C in controlling epithelial barrier integrity and intestinal inflammation. Proc Natl Acad Sci U S A (2011) 0.96
Characterization of streptokinases from group A Streptococci reveals a strong functional relationship that supports the coinheritance of plasminogen-binding M protein and cluster 2b streptokinase. J Biol Chem (2012) 0.96
Platelet dysfunction is an early marker for traumatic brain injury-induced coagulopathy. Neurocrit Care (2013) 0.96
A natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genes. J Biol Chem (2013) 0.95
Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway. Thromb Haemost (2006) 0.93
The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection. Am J Pathol (2003) 0.93
Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden. PLoS One (2010) 0.93
Living-donor right hepatectomy with or without inclusion of middle hepatic vein: comparison of morbidity and outcome in 56 patients. Am J Transplant (2004) 0.93
Prognostic factors affecting the clinical outcome of carcinoma ex pleomorphic adenoma in the major salivary gland. World J Surg Oncol (2013) 0.92
Measurement of oxygen consumption in children undergoing cardiac catheterization: comparison between mass spectrometry and the breath-by-breath method. Pediatr Cardiol (2013) 0.91
Impact of excess body weight on arterial structure, function, and blood pressure in firefighters. Am J Cardiol (2009) 0.90
Structural changes in postural sway lend insight into effects of balance training, vision, and support surface on postural control in a healthy population. Eur J Appl Physiol (2010) 0.90
Type II gall bladder perforation with abdominal wall abscess in a cirrhotic patient: case report and review of the literature. J Surg Educ (2008) 0.89
Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice. Carcinogenesis (2008) 0.88
Calcified fecolith--a rare cause of large bowel obstruction. Emerg Radiol (2006) 0.88
Coagulation factor Xa modulates airway remodeling in a murine model of asthma. Am J Respir Crit Care Med (2006) 0.88
Mutation in integrin-linked kinase (ILK(R211A)) and heat-shock protein 70 comprise a broadly cardioprotective complex. PLoS One (2013) 0.88
Reducing missed injuries at a level II trauma center. J Trauma Nurs (2006) 0.87
Early platelet dysfunction in a rodent model of blunt traumatic brain injury reflects the acute traumatic coagulopathy found in humans. J Neurotrauma (2013) 0.87
Osteogenic potential of human periosteum-derived progenitor cells in PLGA scaffold using allogeneic serum. J Zhejiang Univ Sci B (2006) 0.86
Identification and resuscitation of the trauma patient in shock. Emerg Med Clin North Am (2007) 0.86
Complement-mediated opsonization of invasive group A Streptococcus pyogenes strain AP53 is regulated by the bacterial two-component cluster of virulence responder/sensor (CovRS) system. J Biol Chem (2013) 0.86
Late presentation of anal canal duplication in an adolescent female--a rare diagnosis. Int J Colorectal Dis (2012) 0.85
The current state of pancreatic cancer in Canada: incidence, mortality, and surgical therapy. Pancreas (2014) 0.85
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice. Am J Physiol Lung Cell Mol Physiol (2009) 0.85
Effect of muscle fatigue on the compliance of the gastrocnemius medialis tendon and aponeurosis. J Biomech (2006) 0.84
Core temperature and heart rate response to repeated bouts of firefighting activities. Ergonomics (2013) 0.84
The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain. J Biol Chem (2007) 0.84
Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β-domains. FEBS Lett (2013) 0.84
A deficiency of uPAR alters endothelial angiogenic function and cell morphology. Vasc Cell (2011) 0.84
An unruptured, thrombosed 10 cm right coronary artery aneurysm mimicking a pericardial cyst. J Cardiothorac Surg (2013) 0.83
A semi-automated method for patient-specific computational flow modelling of left ventricles. Comput Methods Biomech Biomed Engin (2013) 0.83
Conantokins inhibit NMDAR-dependent calcium influx in developing rat hippocampal neurons in primary culture with resulting effects on CREB phosphorylation. Mol Cell Neurosci (2010) 0.83
Changes in fascicle length from rest to maximal voluntary contraction affect the assessment of voluntary activation. J Biomech (2007) 0.83
Effects of short-term training using SmartCranks on cycle work distribution and power output during cycling. Eur J Appl Physiol (2008) 0.82
Significant correlation of comprehensive Aristotle score with total cardiac output during the early postoperative period after the Norwood procedure. J Thorac Cardiovasc Surg (2008) 0.82
Fracture blisters. West J Emerg Med (2011) 0.82
Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats. J Trauma Acute Care Surg (2014) 0.82
Early invasive Listeria monocytogenes infection after orthotopic liver transplantation: case report and review of the literature. Liver Transpl (2008) 0.81
Physiological recovery from firefighting activities in rehabilitation and beyond. Prehosp Emerg Care (2011) 0.81
Development and validation of a lateral flow immunoassay using colloidal gold for the identification of serotype-specific foot-and-mouth disease virus O, A and Asia 1. J Virol Methods (2010) 0.81
The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B. Neuropharmacology (2009) 0.81
Fibrinogen has chaperone-like activity. Biochem Biophys Res Commun (2008) 0.81
Percutaneous pulmonary valve implantation within bioprosthetic valves. Eur Heart J (2010) 0.81
C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line. Life Sci (2006) 0.81
An accompanying genetic severe deficiency of tissue factor protects mice with a protein C deficiency from lethal endotoxemia. Blood (2010) 0.81
Focal arterial inflammation is augmented in mice with a deficiency of the protein C gene. Thromb Haemost (2006) 0.80
Firefighter health and fitness assessment: a call to action. J Strength Cond Res (2014) 0.80
Monoclonal gammopathy and glomerulopathy associated with chronic lymphocytic leukemia. Nat Clin Pract Nephrol (2008) 0.80