Published in Thromb Haemost on September 01, 2002
Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med (2007) 3.35
Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J Clin Invest (2009) 1.86
Extraembryonic expression of EPCR is essential for embryonic viability. Blood (2005) 1.49
Heparin rescues factor V Leiden-associated placental failure independent of anticoagulation in a murine high-risk pregnancy model. Blood (2013) 1.43
Retracted Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. Blood (2009) 1.36
Sphingosine 1-phosphate in coagulation and inflammation. Semin Immunopathol (2011) 1.34
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors. J Biol Chem (2010) 1.24
The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications. Blood (2009) 1.21
Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates. Blood (2007) 1.12
Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier. J Cereb Blood Flow Metab (2008) 1.10
PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat Med (2015) 1.08
Endothelial protein C receptor function in murine and human breast cancer development. PLoS One (2013) 1.05
Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice. Blood (2006) 1.04
Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice. J Thromb Haemost (2014) 0.88
Survival advantage of heterozygous factor V Leiden carriers in murine sepsis. J Thromb Haemost (2015) 0.85
Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers. J Exp Med (2007) 0.84
Antibody SPC-54 provides acute in vivo blockage of the murine protein C system. Blood Cells Mol Dis (2013) 0.81
Infrared fluorescence for vascular barrier breach in vivo--a novel method for quantitation of albumin efflux. Thromb Haemost (2012) 0.80
Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. Blood (2015) 0.77
Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity. J Exp Med (2016) 0.75
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. Nat Med (2003) 4.04
Total synthesis of a functional designer eukaryotic chromosome. Science (2014) 3.31
A missense mutation in the sodium phosphate co-transporter Slc34a1 impairs phosphate homeostasis. J Am Soc Nephrol (2008) 1.51
FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse. Thromb Haemost (2002) 1.49
Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization. Stem Cells (2007) 1.45
A multiscale model of thrombus development. J R Soc Interface (2008) 1.42
A cardioprotective role for the endothelial protein C receptor in lipopolysaccharide-induced endotoxemia in the mouse. Blood (2004) 1.35
IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling. Stem Cells (2008) 1.32
A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade. Biophys J (2010) 1.26
Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities. J Clin Invest (2005) 1.17
Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1-deficient mice. J Biol Chem (2003) 1.08
Fibrin networks regulate protein transport during thrombus development. PLoS Comput Biol (2013) 1.04
Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo. Eur J Pharmacol (2009) 1.01
Generation of genetically-altered mice producing very low levels of coagulation factorVII. Thromb Haemost (2005) 1.00
Computational approaches to studying thrombus development. Arterioscler Thromb Vasc Biol (2011) 0.99
Two-photon intravital imaging of thrombus development. J Biomed Opt (2010) 0.97
Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse. Am J Pathol (2002) 0.96
Characterization of streptokinases from group A Streptococci reveals a strong functional relationship that supports the coinheritance of plasminogen-binding M protein and cluster 2b streptokinase. J Biol Chem (2012) 0.96
The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection. Am J Pathol (2003) 0.93
Prognostic factors affecting the clinical outcome of carcinoma ex pleomorphic adenoma in the major salivary gland. World J Surg Oncol (2013) 0.92
Modelling platelet-blood flow interaction using the subcellular element Langevin method. J R Soc Interface (2011) 0.90
Coagulation factor Xa modulates airway remodeling in a murine model of asthma. Am J Respir Crit Care Med (2006) 0.88
Multiscale models of thrombogenesis. Wiley Interdiscip Rev Syst Biol Med (2012) 0.87
Early platelet dysfunction in a rodent model of blunt traumatic brain injury reflects the acute traumatic coagulopathy found in humans. J Neurotrauma (2013) 0.87
Osteogenic potential of human periosteum-derived progenitor cells in PLGA scaffold using allogeneic serum. J Zhejiang Univ Sci B (2006) 0.86
Complement-mediated opsonization of invasive group A Streptococcus pyogenes strain AP53 is regulated by the bacterial two-component cluster of virulence responder/sensor (CovRS) system. J Biol Chem (2013) 0.86
Functional differences between Streptococcus pyogenes cluster 1 and cluster 2b streptokinases are determined by their β-domains. FEBS Lett (2013) 0.84
Identifying and genotyping transgene integration loci. Transgenic Res (2008) 0.84
Prevention of human PC-346C prostate cancer growth in mice by a xenogeneic tissue vaccine. Cancer Immunol Immunother (2007) 0.84
A semi-automated method for patient-specific computational flow modelling of left ventricles. Comput Methods Biomech Biomed Engin (2013) 0.83
Development and validation of a lateral flow immunoassay using colloidal gold for the identification of serotype-specific foot-and-mouth disease virus O, A and Asia 1. J Virol Methods (2010) 0.81
C/T conversion alters interleukin-1A promoter function in a human astrocyte cell line. Life Sci (2006) 0.81
The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B. Neuropharmacology (2009) 0.81
Multiscale model of fibrin accumulation on the blood clot surface and platelet dynamics. Methods Cell Biol (2012) 0.81
Focal arterial inflammation is augmented in mice with a deficiency of the protein C gene. Thromb Haemost (2006) 0.80
A simple and rapid colloidal gold-based immunochromatogarpic strip test for detection of FMDV serotype A. Virol Sin (2011) 0.79
Systemic platelet dysfunction is the result of local dysregulated coagulation and platelet activation in the brain in a rat model of isolated traumatic brain injury. J Neurotrauma (2014) 0.77
Tissue distribution of fetal liver cells following in utero transplantation in mice. Exp Biol Med (Maywood) (2005) 0.77
How to improve the efficacy of endoscopic ultrasound-guided celiac plexus neurolysis in pain management in patients with pancreatic cancer: analysis in a single center. Surg Laparosc Endosc Percutan Tech (2014) 0.76
Vaccination against prostate cancer using a live tissue factor deficient cell line in Lobund-Wistar rats. Cancer Immunol Immunother (2006) 0.76
Mechano-rheological properties of the murine thrombus determined via nanoindentation and finite element modeling. J Mech Behav Biomed Mater (2012) 0.76
Rat prostate tumors express cancer procoagulant, an activator of coagulation factor X. Comp Med (2008) 0.75
Abnormal whole blood thrombi in humans with inherited platelet receptor defects. PLoS One (2012) 0.75
Determination of the left ventricular myofiber angle analytically and its significance. Conf Proc IEEE Eng Med Biol Soc (2005) 0.75
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Tissue vaccines for cancer. Expert Rev Vaccines (2007) 0.75
[Case-control studies on therapeutic effects of combined methods of minimally invasive percutaneous proximal humerus locked osteosynthesis plate with injectable bone for the treatment of proximal humerus fractures in elderly patients]. Zhongguo Gu Shang (2013) 0.75
[Establishment of a colloid gold-immunochromatography assay for detection of type Asia I foot-and-mouth disease virus]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2007) 0.75
Role of sphingosine kinase in the expression of adhesion molecules on monocytes induced by tumor necrosis factor-alpha (relevant to atherosclerosis). Conf Proc IEEE Eng Med Biol Soc (2005) 0.75
Impact of Direct Cardiovascular Laboratory Activation by Emergency Physicians on False-Positive Activation Rates. Ann Acad Med Singapore (2016) 0.75