Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.

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Published in J Immunol on January 09, 2013

Authors

Florina Olaru1, Xu-Ping Wang, Wentian Luo, Linna Ge, Jeffrey H Miner, Sandra Kleinau, Xochiquetzal J Geiger, Andrew Wasiluk, Laurence Heidet, A Richard Kitching, Dorin-Bogdan Borza

Author Affiliations

1: Division of Nephrology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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