Published in PLoS Biol on May 27, 2008
The canonical Notch signaling pathway: unfolding the activation mechanism. Cell (2009) 14.72
A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature (2011) 5.78
Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64
Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 3.33
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest (2015) 2.93
Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol (2010) 2.72
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia. Proc Natl Acad Sci U S A (2009) 2.54
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J Exp Med (2009) 2.45
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell (2009) 2.19
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS One (2010) 1.92
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J Exp Med (2009) 1.83
Metalloproteinases and their natural inhibitors in inflammation and immunity. Nat Rev Immunol (2013) 1.77
Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma. PLoS Biol (2009) 1.76
Notch inhibitors for cancer treatment. Pharmacol Ther (2013) 1.55
Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin. Cancer Cell (2012) 1.54
Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice. J Clin Invest (2011) 1.51
Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol (2012) 1.40
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation. J Exp Med (2012) 1.39
Non-canonical Notch signaling: emerging role and mechanism. Trends Cell Biol (2012) 1.37
Notch signaling. Cold Spring Harb Perspect Biol (2012) 1.35
The role of thymic stromal lymphopoietin (TSLP) in allergic disorders. Curr Opin Immunol (2010) 1.34
Thymic stromal lymphopoietin and allergic disease. J Allergy Clin Immunol (2012) 1.33
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol (2010) 1.32
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors. PLoS One (2010) 1.30
The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling. Development (2011) 1.25
Notch signaling in bulge stem cells is not required for selection of hair follicle fate. Development (2009) 1.23
Thymic stromal lymphopoietin. Ann N Y Acad Sci (2010) 1.21
Dynamic role of epithelium-derived cytokines in asthma. Clin Immunol (2012) 1.14
The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol (2013) 1.12
Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol (2014) 1.11
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development (2012) 1.11
Notch signaling regulates late-stage epidermal differentiation and maintains postnatal hair cycle homeostasis. PLoS One (2011) 1.09
Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc Natl Acad Sci U S A (2010) 1.07
Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation. Proc Natl Acad Sci U S A (2011) 1.05
Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci (2009) 1.04
Alteration of Notch signaling in skeletal development and disease. Ann N Y Acad Sci (2010) 1.04
Functions of thymic stromal lymphopoietin in immunity and disease. Immunol Res (2012) 1.00
Thymic stromal lymphopoietin interferes with airway tolerance by suppressing the generation of antigen-specific regulatory T cells. J Immunol (2011) 1.00
Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease. Immunol Res (2008) 0.98
Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9. J Bone Miner Res (2013) 0.97
The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol (2012) 0.97
Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis. J Clin Invest (2014) 0.96
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility. Elife (2014) 0.95
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development (2010) 0.93
Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7. Oncogene (2010) 0.93
The Role of TSLP in IL-13-induced atopic march. Sci Rep (2011) 0.92
Group 2 innate lymphoid cells utilize the IRF4-IL-9 module to coordinate epithelial cell maintenance of lung homeostasis. Mucosal Immunol (2015) 0.92
Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction. Nat Cell Biol (2015) 0.90
Wound healing and cancer stem cells: inflammation as a driver of treatment resistance in breast cancer. Cancer Growth Metastasis (2015) 0.90
Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice. PLoS One (2012) 0.87
The importance of TSLP in allergic disease and its role as a potential therapeutic target. Expert Rev Clin Immunol (2014) 0.86
Notch signaling in skeletal stem cells. Calcif Tissue Int (2013) 0.86
Epidermal ADAM17 is dispensable for notch activation. J Invest Dermatol (2013) 0.86
Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis. J Clin Invest (2016) 0.86
Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo. Mol Cancer Res (2011) 0.86
Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol (2010) 0.85
Loss of Grainy head-like 1 is associated with disruption of the epidermal barrier and squamous cell carcinoma of the skin. PLoS One (2014) 0.85
Loss of Notch1 disrupts the barrier repair in the corneal epithelium. PLoS One (2013) 0.84
Thymic stromal lymphopoietin and cancer. J Immunol (2014) 0.84
The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation. J Invest Dermatol (2013) 0.83
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7. Int Immunol (2009) 0.83
The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development (2015) 0.83
Noncanonical Notch signaling modulates cytokine responses of dendritic cells to inflammatory stimuli. J Immunol (2012) 0.82
Role of Notch signaling in regulating innate immunity and inflammation in health and disease. Protein Cell (2016) 0.81
Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activity. Development (2015) 0.80
Unusual timing of CD127 expression by mouse uterine natural killer cells. J Leukoc Biol (2012) 0.80
Thymic stromal lymphopoietin expression is increased in the horny layer of patients with atopic dermatitis. Clin Exp Immunol (2013) 0.79
The anatomical distribution of genetic associations. Nucleic Acids Res (2015) 0.78
Cutaneous Notch signaling in health and disease. Cold Spring Harb Perspect Med (2013) 0.78
Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects. J Bone Miner Res (2015) 0.77
Circulating TSLP associates with decreased wheezing in non-atopic preschool children: data from the URECA birth cohort. Clin Exp Allergy (2014) 0.76
The role of barrier genes in epidermal malignancy. Oncogene (2016) 0.76
When skin damage causes death. PLoS Biol (2008) 0.76
The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development. J Invest Dermatol (2016) 0.75
Direct control of regulatory T cells by keratinocytes. Nat Immunol (2017) 0.75
Thymic stromal lymphopoietin in hepatitis C virus-related cryoglobulinemic vasculitis: gene expression level and protein distribution. Arthritis Res Ther (2015) 0.75
Notch as a tumour suppressor. Nat Rev Cancer (2017) 0.75
Analysis of chromatin accessibility in human epidermis identifies putative barrier dysfunction-sensing enhancers. PLoS One (2017) 0.75
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proc Natl Acad Sci U S A (2006) 10.65
A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem (1997) 5.14
Getting under the skin of epidermal morphogenesis. Nat Rev Genet (2002) 4.54
Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol (2002) 4.29
Epidermal barrier formation and recovery in skin disorders. J Clin Invest (2006) 4.14
Patterned acquisition of skin barrier function during development. Development (1998) 3.88
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J Exp Med (2007) 3.66
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med (2008) 3.64
Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51
Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med (2006) 3.25
A role for thymic stromal lymphopoietin in CD4(+) T cell development. J Exp Med (2004) 2.81
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell (2004) 2.68
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev (1996) 2.61
Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB. Proc Natl Acad Sci U S A (2007) 2.51
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development. Nat Immunol (2003) 2.24
Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell (2005) 2.21
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev (2005) 2.17
The hematopoietic stem cell and its niche: a comparative view. Genes Dev (2007) 2.15
Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice. J Exp Med (2001) 2.06
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem (2007) 1.99
Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation. Genes Dev (2002) 1.97
The epithelium takes centre stage in asthma and atopic dermatitis. Trends Immunol (2007) 1.84
High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell (2004) 1.78
CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? Curr Opin Genet Dev (2002) 1.68
Notch and the immune system. Immunity (2003) 1.66
Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol (2002) 1.65
TSLP: finally in the limelight. Nat Immunol (2002) 1.47
Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes. Development (2007) 1.46
Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing. Biol Cell (2005) 1.43
Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation. Nat Cell Biol (2007) 1.40
Notch signaling in lymphopoiesis. Semin Immunol (2003) 1.37
Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. Proc Natl Acad Sci U S A (2003) 1.35
Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood (2007) 1.34
It's got you covered. NF-kappaB in the epidermis. J Cell Biol (2000) 1.27
Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis. Blood (2003) 1.21
Activation of Notch1 in the hair follicle leads to cell-fate switch and Mohawk alopecia. Differentiation (2004) 1.17
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat Genet (2005) 1.16
Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail. Dev Biol (2003) 1.15
Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis. Dev Biol (2005) 1.13
Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth. Proc Natl Acad Sci U S A (2006) 1.12
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment. Proc Natl Acad Sci U S A (2004) 1.11
Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. Dev Biol (2005) 1.04
Thymic stromal lymphopoietin:a potential therapeutic target for allergy and asthma. Curr Allergy Asthma Rep (2006) 1.00
Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage. Biochemistry (2004) 0.97
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Somatic mutations affect key pathways in lung adenocarcinoma. Nature (2008) 30.02
Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity (2005) 23.00
A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol (2008) 6.78
The genome of the model beetle and pest Tribolium castaneum. Nature (2008) 6.50
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest (2003) 6.44
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature (2010) 5.97
Exploration of essential gene functions via titratable promoter alleles. Cell (2004) 5.21
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell (2004) 4.91
Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: an update of radiation therapy oncology group trial (RTOG) 90-01. J Clin Oncol (2004) 4.69
Developmental regulation of Foxp3 expression during ontogeny. J Exp Med (2005) 4.32
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu Rev Neurosci (2003) 3.79
Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development. Dev Cell (2010) 3.78
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med (2008) 3.64
CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science (2003) 3.61
Role of COL4A1 in small-vessel disease and hemorrhagic stroke. N Engl J Med (2006) 3.58
Intramembrane proteolysis: theme and variations. Science (2004) 3.06
Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity. Proc Natl Acad Sci U S A (2005) 3.01
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat Immunol (2011) 2.99
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells. Gastroenterology (2011) 2.94
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes. Proc Natl Acad Sci U S A (2005) 2.85
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (2007) 2.70
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell (2004) 2.68
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev Biol (2004) 2.59
Measurement of tumor volume by PET to evaluate prognosis in patients with advanced cervical cancer treated by radiation therapy. Int J Radiat Oncol Biol Phys (2002) 2.55
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med (2010) 2.44
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man. Dev Cell (2012) 2.43
Transcriptional architecture of the primate neocortex. Neuron (2012) 2.42
The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development (2005) 2.36
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice. Proc Natl Acad Sci U S A (2010) 2.34
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability. J Biol Chem (2005) 2.33
The standardized uptake value for F-18 fluorodeoxyglucose is a sensitive predictive biomarker for cervical cancer treatment response and survival. Cancer (2007) 2.30
A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. Gynecol Oncol (2009) 2.26
Differentiation of regulatory Foxp3+ T cells in the thymic cortex. Proc Natl Acad Sci U S A (2008) 2.24
Association of posttherapy positron emission tomography with tumor response and survival in cervical carcinoma. JAMA (2007) 2.22
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment. Cancer Cell (2009) 2.19
A microRNA expression signature for cervical cancer prognosis. Cancer Res (2010) 2.14
Podocytes use FcRn to clear IgG from the glomerular basement membrane. Proc Natl Acad Sci U S A (2008) 2.12
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol (2006) 2.10
Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM: relationship to therapeutic response-a preliminary report. Int J Radiat Oncol Biol Phys (2003) 2.09
Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci (2010) 2.07
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood (2004) 2.06
Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy. J Invest Dermatol (2005) 2.06
Positron emission tomography with [(18)F]-3'-deoxy-3'fluorothymidine (FLT) as a predictor of outcome in patients with locally advanced resectable rectal cancer: a pilot study. Mol Imaging Biol (2013) 2.05
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell (2003) 2.05
Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. Int J Radiat Oncol Biol Phys (2009) 2.05
NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem (2007) 1.99
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE. Development (2007) 1.94
Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier. J Clin Invest (2006) 1.93
A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis. Proc Natl Acad Sci U S A (2003) 1.92
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. PLoS One (2010) 1.92
RovA, a global regulator of Yersinia pestis, specifically required for bubonic plague. Proc Natl Acad Sci U S A (2006) 1.92
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol (2013) 1.87
Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney. Development (2003) 1.87
Progress toward a microradiation therapy small animal conformal irradiator. Med Phys (2006) 1.84
Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. J Biol Chem (2009) 1.83
Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma. PLoS Biol (2009) 1.76
Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Res (2010) 1.75
Intratumoral metabolic heterogeneity of cervical cancer. Clin Cancer Res (2008) 1.74
Maintenance of glomerular filtration barrier integrity requires laminin alpha5. J Am Soc Nephrol (2010) 1.73
Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis. J Am Soc Nephrol (2006) 1.70
Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen. J Am Soc Nephrol (2005) 1.69
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors. Blood (2004) 1.68
Cervical carcinoma in the elderly: an analysis of patterns of care and outcome. Cancer (2005) 1.68
Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome. Am J Pathol (2002) 1.67
Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest (2006) 1.66
Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol (2002) 1.65
SnapShot: notch signaling pathway. Cell (2007) 1.63
Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation. Dev Cell (2005) 1.62
Partial rescue of glomerular laminin alpha5 mutations by wild-type endothelia produce hybrid glomeruli. J Am Soc Nephrol (2007) 1.62
Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data. Mol Cell (2004) 1.62
Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration. Nat Med (2004) 1.60
Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol (2008) 1.59
Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. J Clin Invest (2014) 1.58
Regulation of thymic epithelium by keratinocyte growth factor. Blood (2002) 1.57
Coordinate control of axon defasciculation and myelination by laminin-2 and -8. J Cell Biol (2005) 1.56
Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS One (2008) 1.56
Lymph node staging by positron emission tomography in cervical cancer: relationship to prognosis. J Clin Oncol (2010) 1.55
Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin. Cancer Cell (2012) 1.54
Development of a DNA microarray for toxicology based on hepatotoxin-regulated sequences. EHP Toxicogenomics (2003) 1.54
GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling. Hum Mol Genet (2011) 1.52
Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice. J Clin Invest (2011) 1.51
Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone). J Nucl Med (2008) 1.51
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem (2011) 1.51
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile. Aging Cell (2013) 1.48
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis. J Clin Invest (2016) 1.48
Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation. J Immunol (2007) 1.46
Albumin-associated free fatty acids induce macropinocytosis in podocytes. J Clin Invest (2015) 1.46
Magnitude of interfractional vaginal cuff movement: implications for external irradiation. Int J Radiat Oncol Biol Phys (2011) 1.46
Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes. Development (2007) 1.46
Ectodomain shedding and intramembrane cleavage of mammalian Notch proteins is not regulated through oligomerization. J Biol Chem (2004) 1.45
Beta1-integrins are critical for cerebellar granule cell precursor proliferation. J Neurosci (2004) 1.44