Published in Cardiovasc Drugs Ther on April 01, 2013
Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future. Br J Pharmacol (2014) 0.90
Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther (2013) 0.89
Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery. Basic Res Cardiol (2016) 0.87
Triple therapy greatly increases myocardial salvage during ischemia/reperfusion in the in situ rat heart. Cardiovasc Drugs Ther (2013) 0.85
Cardioprotective Properties of the Platelet P2Y12 Receptor Inhibitor, Cangrelor: Protective in Diabetics and Reliant Upon the Presence of Blood. Cardiovasc Drugs Ther (2015) 0.76
Cardioprotection--time to take into account clinical complexity: the case of antiplatelet agents : editorial to "two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts" by Xi-Ming Yang et al. Cardiovasc Drugs Ther (2013) 0.75
New and revisited approaches to preserving the reperfused myocardium. Nat Rev Cardiol (2017) 0.75
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Protecting the acutely ischemic myocardium beyond reperfusion therapies: are we any closer to realizing the dream of infarct size elimination? Arch Mal Coeur Vaiss (2007) 1.06
Platelet P2Y₁₂ blockers confer direct postconditioning-like protection in reperfused rabbit hearts. J Cardiovasc Pharmacol Ther (2012) 1.04
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Myocardial salvage in acute myocardial infarction--challenges in clinical translation. J Mol Cell Cardiol (2011) 0.98
P2Y12 platelet inhibition in clinical practice. J Thromb Thrombolysis (2012) 0.97
Antagonism of P2Y12 or GPIIb/IIIa receptors reduces platelet-mediated myocardial injury after ischaemia and reperfusion in isolated rat hearts. Thromb Haemost (2010) 0.96
Attenuation of infarction in cynomolgus monkeys: preconditioning and postconditioning. Basic Res Cardiol (2009) 0.93
Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion. Heart (2005) 0.92
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The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats. Arterioscler Thromb Vasc Biol (2007) 0.88
Impaired platelet function reduces myocardial infarct size in Galphaq knock-out mice in vivo. J Mol Cell Cardiol (2007) 0.86
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Duration and reinstatement of myocardial protection against infarction by ischemic preconditioning in open chest dogs. J Mol Cell Cardiol (2001) 0.85
Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor gamma-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury. J Mol Cell Cardiol (2005) 0.85
Lack of effect of glycoprotein IIb/IIIa blockade on myocardial platelet or polymorphonuclear leukocyte accumulation and on infarct size after transient coronary occlusion in pigs. J Am Coll Cardiol (2002) 0.84
Platelet GPIIb/IIIa receptor blockade reduces infarct size in a canine model of ischemia-reperfusion. J Am Coll Cardiol (2000) 0.84
Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev (2003) 3.83
2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA (2010) 3.05
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol (2004) 2.94
Masked hypertension in diabetes mellitus: treatment implications for clinical practice. Hypertension (2013) 2.89
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade. Cardiovasc Res (2006) 2.39
Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Res (2014) 2.34
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Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane. Science (2002) 2.23
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Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria. Circ Res (2005) 1.86
Oseltamivir ring prophylaxis for containment of 2009 H1N1 influenza outbreaks. N Engl J Med (2010) 1.79
In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain. Exp Neurol (2008) 1.73
Total liquid ventilation provides ultra-fast cardioprotective cooling. J Am Coll Cardiol (2007) 1.73
Effects of early oseltamivir therapy on viral shedding in 2009 pandemic influenza A (H1N1) virus infection. Clin Infect Dis (2010) 1.72
Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection. Am J Physiol Heart Circ Physiol (2003) 1.63
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation (2007) 1.61
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt. Am J Physiol Heart Circ Physiol (2005) 1.59
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion. J Mol Cell Cardiol (2007) 1.58
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Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiol Dis (2005) 1.42
Dose-response relationships of the protective and antiprotective effects of acute ethanol exposure in isolated rabbit hearts. Heart Dis (2002) 1.42
Mechanism of cardioprotection by early ischemic preconditioning. Cardiovasc Drugs Ther (2010) 1.41
Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol (2004) 1.41
Why do we still not have cardioprotective drugs? Circ J (2009) 1.40
Adenosine: trigger and mediator of cardioprotection. Basic Res Cardiol (2007) 1.38
Bypassing big pharma. Circulation (2007) 1.38
A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus. PLoS Curr (2010) 1.37
Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies. Cardiovasc Res (2005) 1.33
CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer. Gastroenterology (2010) 1.33
NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol (2004) 1.29
Effectiveness of public health measures in mitigating pandemic influenza spread: a prospective sero-epidemiological cohort study. J Infect Dis (2010) 1.26
cGMP signalling in pre- and post-conditioning: the role of mitochondria. Cardiovasc Res (2007) 1.25
Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains. Vaccine (2010) 1.23
Mitochondrial K(ATP) channels: role in cardioprotection. Cardiovasc Res (2002) 1.17
A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs. PLoS One (2013) 1.16
Inhibition of collagen-induced platelet aggregation by anopheline antiplatelet protein, a saliva protein from a malaria vector mosquito. Blood (2007) 1.16
Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success. Basic Res Cardiol (2008) 1.14
Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells. Am J Physiol Heart Circ Physiol (2003) 1.14
Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice. J Cereb Blood Flow Metab (2006) 1.13
Cilostazol as a unique antithrombotic agent. Curr Pharm Des (2003) 1.13
Cardioprotective PKG-independent NO signaling at reperfusion. Am J Physiol Heart Circ Physiol (2010) 1.12
Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res (2004) 1.11
South-east Asian Zika virus strain linked to cluster of cases in Singapore, August 2016. Euro Surveill (2016) 1.11
The prognostic role of RASSF1A promoter methylation in breast cancer: a meta-analysis of published data. PLoS One (2012) 1.08
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Basic Res Cardiol (2006) 1.07
Exogenous NO triggers preconditioning via a cGMP- and mitoKATP-dependent mechanism. Am J Physiol Heart Circ Physiol (2004) 1.06
Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells. Cancer Res (2013) 1.06
Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells. Cancer (2010) 1.05
Mapping preconditioning's signaling pathways: an engineering approach. Ann N Y Acad Sci (2008) 1.05
Platelet P2Y₁₂ blockers confer direct postconditioning-like protection in reperfused rabbit hearts. J Cardiovasc Pharmacol Ther (2012) 1.04
BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts. Eur Heart J (2009) 1.04
ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases. Am J Physiol Heart Circ Physiol (2002) 1.03
Therapeutic potential of phosphodiesterase inhibitors in parasitic diseases. Handb Exp Pharmacol (2011) 1.03
Betulin induces mitochondrial cytochrome c release associated apoptosis in human cancer cells. Mol Carcinog (2010) 1.02
Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice. Cell Signal (2007) 1.01
Significance of combination therapy of zoledronic acid and gemcitabine on pancreatic cancer. Cancer Sci (2011) 1.01
Tumor-stromal interactions with direct cell contacts enhance proliferation of human pancreatic carcinoma cells. Cancer Sci (2009) 1.01
Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts. Am J Physiol Heart Circ Physiol (2010) 1.00
Protection from post-conditioning depends on the number of short ischemic insults in anesthetized pigs. Basic Res Cardiol (2006) 1.00
Ischemic postconditioning: from receptor to end-effector. Antioxid Redox Signal (2010) 0.98
Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts. Basic Res Cardiol (2006) 0.98
Redox modulation of vascular tone: focus of potassium channel mechanisms of dilation. Arterioscler Thromb Vasc Biol (2005) 0.98
The small chill: mild hypothermia for cardioprotection? Cardiovasc Res (2010) 0.97