Published in J Am Coll Cardiol on September 01, 2004
Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. Physiol Rev (2008) 5.52
Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection. Heart Fail Rev (2007) 2.14
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. Anesthesiology (2008) 2.14
Remote ischaemic pre- and delayed postconditioning - similar degree of cardioprotection but distinct mechanisms. Exp Physiol (2012) 1.80
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion. J Mol Cell Cardiol (2007) 1.58
Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling. Br J Pharmacol (2007) 1.52
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Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside. Crit Care (2015) 1.46
Potential therapeutic benefits of strategies directed to mitochondria. Antioxid Redox Signal (2010) 1.40
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Effects of diabetes on myocardial infarct size and cardioprotection by preconditioning and postconditioning. Cardiovasc Diabetol (2012) 1.21
Postconditioning: old wine in a new bottle? J Am Coll Cardiol (2004) 1.19
Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetes. Antioxid Redox Signal (2010) 1.17
Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success. Basic Res Cardiol (2008) 1.14
Cardioprotection by postconditioning in conscious rats is limited to coronary occlusions <45 min. Am J Physiol Heart Circ Physiol (2006) 1.13
Protective ischaemia in patients: preconditioning and postconditioning. Cardiovasc Res (2009) 1.10
Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway. J Biomed Sci (2011) 1.09
MG53 participates in ischaemic postconditioning through the RISK signalling pathway. Cardiovasc Res (2011) 1.09
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The paradigm of postconditioning to protect the heart. J Cell Mol Med (2007) 1.07
Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol-independent action at reperfusion. Br J Pharmacol (2010) 1.05
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Cardioprotective effects of mineralocorticoid receptor antagonists at reperfusion. Eur Heart J (2009) 1.03
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest (2015) 1.00
A role for the RISK pathway and K(ATP) channels in pre- and post-conditioning induced by levosimendan in the isolated guinea pig heart. Br J Pharmacol (2008) 0.98
Connexin 43 in ischemic pre- and postconditioning. Heart Fail Rev (2007) 0.97
Infarct limitation by a protein kinase G activator at reperfusion in rabbit hearts is dependent on sensitizing the heart to A2b agonists by protein kinase C. Am J Physiol Heart Circ Physiol (2008) 0.96
Cellular postconditioning: allogeneic cardiosphere-derived cells reduce infarct size and attenuate microvascular obstruction when administered after reperfusion in pigs with acute myocardial infarction. Circ Heart Fail (2015) 0.94
Postconditioning: a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion. Heart Fail Rev (2007) 0.94
Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury. J Cereb Blood Flow Metab (2012) 0.94
Postconditioning leads to an increase in protein S-nitrosylation. Am J Physiol Heart Circ Physiol (2014) 0.93
Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future. Br J Pharmacol (2014) 0.90
Postconditioning signalling in the heart: mechanisms and translatability. Br J Pharmacol (2014) 0.88
Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning. Basic Res Cardiol (2008) 0.87
Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery. Basic Res Cardiol (2016) 0.87
K(ATP) channel-dependent metaboproteome decoded: systems approaches to heart failure prediction, diagnosis, and therapy. Cardiovasc Res (2011) 0.86
Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation. J Transplant (2012) 0.86
The cGMP/PKG pathway as a common mediator of cardioprotection: translatability and mechanism. Br J Pharmacol (2015) 0.85
Postconditioning, a series of brief interruptions of early reperfusion, prevents neurologic injury after spinal cord ischemia. Ann Surg (2006) 0.85
Cardiomyocyte overexpression of the α1A-adrenergic receptor in the rat phenocopies second but not first window preconditioning. Am J Physiol Heart Circ Physiol (2012) 0.84
Endothelial NOS activity and myocardial oxygen metabolism define the salvageable ischemic time window for ischemic postconditioning. Am J Physiol Heart Circ Physiol (2011) 0.84
Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts. PeerJ (2016) 0.83
Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway. Cardiovasc Res (2015) 0.83
The Protective Effects of Ischemic Postconditioning against Stroke: From Rapid to Delayed and Remote Postconditioning. Open Drug Discov J (2011) 0.83
Protection of the ischemic myocardium during the reperfusion: between hope and reality. Am J Cardiovasc Dis (2012) 0.83
Transient acidosis during early reperfusion attenuates myocardium ischemia reperfusion injury via PI3k-Akt-eNOS signaling pathway. Oxid Med Cell Longev (2013) 0.83
Cardiac Mechano-Gated Ion Channels and Arrhythmias. Circ Res (2016) 0.82
Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis. Oxid Med Cell Longev (2015) 0.82
Myocardial ischemic conditioning: Physiological aspects and clinical applications in cardiac surgery. J Saudi Heart Assoc (2013) 0.81
The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats. Am J Physiol Heart Circ Physiol (2007) 0.80
Intermittent losartan administration triggers cardiac post-conditioning in isolated rat hearts: role of BK2 receptors. PLoS One (2014) 0.78
Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning. Basic Res Cardiol (2014) 0.78
Protective Effects of Shen-Yuan-Dan, a Traditional Chinese Medicine, against Myocardial Ischemia/Reperfusion Injury In Vivo and In Vitro. Evid Based Complement Alternat Med (2013) 0.78
Remifentanil functions in the adaptive protection of cardiac function following ischemia. Exp Ther Med (2017) 0.77
Rapid ventricular pacing-induced postconditioning attenuates reperfusion injury: effects on peroxynitrite, RISK and SAFE pathways. Br J Pharmacol (2015) 0.77
Ischemic postconditioning and pinacidil suppress calcium overload in anoxia-reoxygenation cardiomyocytes via down-regulation of the calcium-sensing receptor. PeerJ (2016) 0.77
Adenosine diphosphate reduces infarct size and improves porcine heart function after myocardial infarct. Physiol Rep (2013) 0.77
Post-conditioning with gradually increased reperfusion provides better cardioprotection in rats. World J Emerg Med (2014) 0.77
Ischaemic postconditioning: from bench to bedside ... Cardiovasc J Afr (2008) 0.76
Biological networks in ischemic tolerance - rethinking the approach to clinical conditioning. Transl Stroke Res (2013) 0.76
Combination of remote ischemic perconditioning and remote ischemic postconditioning fails to increase protection against myocardial ischemia/reperfusion injury, compared with either alone. Mol Med Rep (2015) 0.75
ATP-induced cardioprotection against myocardial ischemia/reperfusion injury is mediated through the RISK pathway. Exp Ther Med (2016) 0.75
Overview of Experimental and Clinical Findings regarding the Neuroprotective Effects of Cerebral Ischemic Postconditioning. Biomed Res Int (2017) 0.75
Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial KATP channels. Sci Rep (2016) 0.75
Mechanical post-conditioning in STEMI patients undergoing primary percutaneous coronary intervention. J Saudi Heart Assoc (2014) 0.75
Modulation of receptor sensitivity: possible therapeutic target? Br J Pharmacol (2009) 0.75
Scleroderma. N Engl J Med (2009) 6.50
Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol (2007) 5.16
Preconditioning the myocardium: from cellular physiology to clinical cardiology. Physiol Rev (2003) 3.83
Differential roles of macrophages in diverse phases of skin repair. J Immunol (2010) 3.56
Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol (2007) 3.51
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature (2002) 3.21
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nat Med (2013) 3.10
2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA (2010) 3.05
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med (2004) 2.58
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood (2012) 2.43
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade. Cardiovasc Res (2006) 2.39
Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity (2011) 2.39
Signaling pathways in ischemic preconditioning. Heart Fail Rev (2007) 2.26
alpha-Smooth Muscle Actin Expressing Stroma Promotes an Aggressive Tumor Biology in Pancreatic Ductal Adenocarcinoma. Pancreas (2010) 1.94
Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria. Circ Res (2005) 1.86
Oseltamivir ring prophylaxis for containment of 2009 H1N1 influenza outbreaks. N Engl J Med (2010) 1.79
In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain. Exp Neurol (2008) 1.73
Total liquid ventilation provides ultra-fast cardioprotective cooling. J Am Coll Cardiol (2007) 1.73
Effects of early oseltamivir therapy on viral shedding in 2009 pandemic influenza A (H1N1) virus infection. Clin Infect Dis (2010) 1.72
Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem (2002) 1.66
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J Clin Invest (2006) 1.65
Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection. Am J Physiol Heart Circ Physiol (2003) 1.63
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation (2007) 1.61
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt. Am J Physiol Heart Circ Physiol (2005) 1.59
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion. J Mol Cell Cardiol (2007) 1.58
Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. J Invest Dermatol (2006) 1.54
New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma. Curr Rheumatol Rep (2007) 1.54
Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA. Eur J Immunol (2006) 1.51
Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts. Cardiovasc Drugs Ther (2013) 1.51
Impact of silver nanoparticles on human cells: effect of particle size. Nanotoxicology (2010) 1.49
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis (2004) 1.48
Merkel cell polyomavirus DNA in persons without merkel cell carcinoma. Emerg Infect Dis (2009) 1.45
Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J Allergy Clin Immunol (2006) 1.43
Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiol Dis (2005) 1.42
Interrelation of immunity and tissue repair or regeneration. Semin Cell Dev Biol (2009) 1.42
Dose-response relationships of the protective and antiprotective effects of acute ethanol exposure in isolated rabbit hearts. Heart Dis (2002) 1.42
Mechanism of cardioprotection by early ischemic preconditioning. Cardiovasc Drugs Ther (2010) 1.41
A2b adenosine receptors in cardioprotection: timing is everything. J Mol Cell Cardiol (2010) 1.41
Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol (2004) 1.41
Why do we still not have cardioprotective drugs? Circ J (2009) 1.40
Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1. J Cell Sci (2007) 1.39
Adenosine: trigger and mediator of cardioprotection. Basic Res Cardiol (2007) 1.38
Bypassing big pharma. Circulation (2007) 1.38
A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus. PLoS Curr (2010) 1.37
Mast cell-specific Cre/loxP-mediated recombination in vivo. Transgenic Res (2007) 1.36
Keloids--clinical diagnosis, pathogenesis, and treatment options. J Dtsch Dermatol Ges (2004) 1.34
Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies. Cardiovasc Res (2005) 1.33
CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer. Gastroenterology (2010) 1.33
Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo. Blood (2003) 1.32
NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol (2004) 1.29
Mechanical tension and integrin alpha 2 beta 1 regulate fibroblast functions. J Investig Dermatol Symp Proc (2006) 1.26
Effectiveness of public health measures in mitigating pandemic influenza spread: a prospective sero-epidemiological cohort study. J Infect Dis (2010) 1.26
cGMP signalling in pre- and post-conditioning: the role of mitochondria. Cardiovasc Res (2007) 1.25
Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains. Vaccine (2010) 1.23
Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas. Int J Cancer (2002) 1.23
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling. Hum Mol Genet (2006) 1.22
Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation. EMBO J (2005) 1.22
Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo. J Cell Sci (2010) 1.21
Protection through postconditioning or a mitochondria-targeted S-nitrosothiol is unaffected by cardiomyocyte-selective ablation of protein kinase G. Basic Res Cardiol (2013) 1.21
Mitochondrial K(ATP) channels: role in cardioprotection. Cardiovasc Res (2002) 1.17
Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of alpha2beta1 integrin. J Cell Sci (2006) 1.17
Home telemonitoring in patients with chronic heart failure: a chance to improve patient care? Dtsch Arztebl Int (2010) 1.17
A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs. PLoS One (2013) 1.16
XIAP expression is an independent prognostic marker in clear-cell renal carcinomas. Hum Pathol (2004) 1.16
Dissecting the roles of endothelin, TGF-beta and GM-CSF on myofibroblast differentiation by keratinocytes. Thromb Haemost (2004) 1.15
Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo. Free Radic Biol Med (2005) 1.14
Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success. Basic Res Cardiol (2008) 1.14
Phosphodiesterase type 5 inhibition is a novel therapeutic option in Raynaud disease. Arch Intern Med (2006) 1.14
Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice. J Cereb Blood Flow Metab (2006) 1.13
Silicone granuloma of the face treated with minocycline. J Am Acad Dermatol (2005) 1.12
Cardioprotective PKG-independent NO signaling at reperfusion. Am J Physiol Heart Circ Physiol (2010) 1.12
Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res (2004) 1.11
South-east Asian Zika virus strain linked to cluster of cases in Singapore, August 2016. Euro Surveill (2016) 1.11
Cell-matrix interactions in dermal repair and scarring. Fibrogenesis Tissue Repair (2010) 1.11
Differential proteomic analysis distinguishes tissue repair biomarker signatures in wound exudates obtained from normal healing and chronic wounds. J Proteome Res (2010) 1.10
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. Eur J Heart Fail (2008) 1.10
Accelerated wound closure in mice deficient for interleukin-10. Am J Pathol (2007) 1.09
Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair. Am J Pathol (2006) 1.09