The dynamic influence of commensal bacteria on the immune response to pathogens.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 3622187)

Published in Curr Opin Microbiol on January 17, 2013

Authors

Michael C Abt1, David Artis

Author Affiliations

1: Department of Microbiology and Institute for Immunology, University of Pennsylvania, Philadelphia, PA 19104, USA.

Articles cited by this

An obesity-associated gut microbiome with increased capacity for energy harvest. Nature (2006) 44.35

Transforming growth factor-beta induces development of the T(H)17 lineage. Nature (2006) 25.91

Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell (2009) 20.29

Functional role of type I and type II interferons in antiviral defense. Science (1994) 18.92

Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell (2006) 18.83

Commensal host-bacterial relationships in the gut. Science (2001) 14.82

The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol (2009) 13.87

Molecular analysis of commensal host-microbial relationships in the intestine. Science (2001) 12.04

An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature (2007) 10.92

Interactions between the microbiota and the immune system. Science (2012) 10.45

Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science (2006) 9.95

Interactions between commensal intestinal bacteria and the immune system. Nat Rev Immunol (2004) 8.45

The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science (2011) 7.07

The impact of the gut microbiota on human health: an integrative view. Cell (2012) 6.01

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell (2006) 5.97

Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses. Immunity (2008) 5.82

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78

Outbreak of Clostridium difficile infection in a long-term care facility: association with gatifloxacin use. Clin Infect Dis (2004) 5.67

Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proc Natl Acad Sci U S A (2011) 5.44

Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut (2004) 5.32

Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients. N Engl J Med (2000) 5.08

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med (2010) 4.98

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits. Nature (2008) 4.87

Type I interferon: friend or foe? J Exp Med (2010) 4.40

Compartmentalized control of skin immunity by resident commensals. Science (2012) 4.19

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science (2012) 4.17

Intestinal floras of populations that have a high risk of colon cancer. Appl Environ Microbiol (1995) 3.77

The microbiome in infectious disease and inflammation. Annu Rev Immunol (2012) 3.76

Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun (2008) 3.68

Intestinal microbiota promote enteric virus replication and systemic pathogenesis. Science (2011) 3.62

Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota. Semin Immunol (2006) 3.48

Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity (2012) 3.47

Successful transmission of a retrovirus depends on the commensal microbiota. Science (2011) 3.34

Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals. N Engl J Med (1999) 2.87

Gut commensal bacteria direct a protective immune response against Toxoplasma gondii. Cell Host Microbe (2009) 2.67

A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses. Proc Natl Acad Sci U S A (1995) 2.57

Role of the commensal microbiota in normal and pathogenic host immune responses. Cell Host Microbe (2011) 2.46

Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection. Infect Immun (2009) 2.26

Antibiotic treatment alters the colonic mucus layer and predisposes the host to exacerbated Citrobacter rodentium-induced colitis. Infect Immun (2011) 2.24

Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota. Immunity (2012) 2.23

Exploitation of the intestinal microflora by the parasitic nematode Trichuris muris. Science (2010) 1.98

The effect of vancomycin and third-generation cephalosporins on prevalence of vancomycin-resistant enterococci in 126 U.S. adult intensive care units. Ann Intern Med (2001) 1.72

Microbiota, disease, and back to health: a metastable journey. Sci Transl Med (2012) 1.70

Antibiotic use in children is associated with increased risk of asthma. Pediatrics (2009) 1.68

Perturbation of the small intestine microbial ecology by streptomycin alters pathology in a Salmonella enterica serovar typhimurium murine model of infection. Infect Immun (2009) 1.59

Increased susceptibility to primary infection with Listeria monocytogenes in germfree mice may be due to lack of accumulation of L-selectin+ CD44+ T cells in sites of inflammation. Infect Immun (1996) 1.11

Germ-free mice produce high levels of interferon-gamma in response to infection with Leishmania major but fail to heal lesions. Parasitology (2005) 0.85

Articles by these authors

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature (2009) 8.71

Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol (2011) 6.73

IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses. Nature (2010) 5.07

Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature (2007) 4.68

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22. Nat Immunol (2011) 4.64

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol (2009) 4.28

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science (2012) 4.20

CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut. Immunity (2010) 4.19

Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity (2012) 3.47

IL-35-mediated induction of a potent regulatory T cell population. Nat Immunol (2010) 3.43

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med (2006) 3.36

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 3.33

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria. Nature (2013) 3.21

Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nat Med (2013) 2.94

Notch signaling is an important regulator of type 2 immunity. J Exp Med (2005) 2.87

Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol (2010) 2.85

Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol (2010) 2.72

Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J Immunol (2012) 2.70

TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation. Sci Transl Med (2013) 2.64

Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine. J Exp Med (2008) 2.63

Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung. J Exp Med (2009) 2.51

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat Med (2012) 2.49

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J Exp Med (2009) 2.45

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature (2011) 2.42

Regulation of pathogenesis and immunity in helminth infections. J Exp Med (2009) 2.39

Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A. J Exp Med (2010) 2.30

New paradigms in type 2 immunity. Science (2012) 2.27

Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora. Immunity (2013) 2.01

Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy. J Immunol (2006) 1.94

Commensal bacteria at the interface of host metabolism and the immune system. Nat Immunol (2013) 1.93

Community-wide response of the gut microbiota to enteropathogenic Citrobacter rodentium infection revealed by deep sequencing. Infect Immun (2009) 1.91

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol (2013) 1.91

Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J Allergy Clin Immunol (2006) 1.79

Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease. Immunity (2012) 1.73

T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity (2013) 1.72

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat Immunol (2011) 1.67

Cutting edge: Natural helper cells derive from lymphoid progenitors. J Immunol (2011) 1.67

Functional biology of the IL-22-IL-22R pathway in regulating immunity and inflammation at barrier surfaces. Adv Immunol (2010) 1.64

Innate immune cell populations function as initiators and effectors in Th2 cytokine responses. Trends Immunol (2010) 1.61

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis. Nature (2013) 1.59

The intestinal microbiota in health and disease: the influence of microbial products on immune cell homeostasis. Curr Opin Gastroenterol (2009) 1.57

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev (2011) 1.54

On the hunt for helminths: innate immune cells in the recognition and response to helminth parasites. Cell Microbiol (2008) 1.50

The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development. Immunol Rev (2004) 1.44

Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation. J Immunol (2008) 1.41

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med (2013) 1.39

IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. J Exp Med (2007) 1.34

Persistence and function of central and effector memory CD4+ T cells following infection with a gastrointestinal helminth. J Immunol (2006) 1.33

Regulation of RELM/FIZZ isoform expression by Cdx2 in response to innate and adaptive immune stimulation in the intestine. Am J Physiol Gastrointest Liver Physiol (2004) 1.31

Basophils and allergic inflammation. J Allergy Clin Immunol (2013) 1.29

Innate lymphoid cells: balancing immunity, inflammation, and tissue repair in the intestine. Cell Host Microbe (2012) 1.29

Cooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity. PLoS Pathog (2013) 1.28

Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung. Curr Opin Immunol (2012) 1.25

Colitis and intestinal inflammation in IL10-/- mice results from IL-13Rα2-mediated attenuation of IL-13 activity. Gastroenterology (2010) 1.22

IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis. J Immunol (2009) 1.21

Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. Immunity (2013) 1.20

A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples. Genome Biol (2012) 1.17

New paradigms in basophil development, regulation and function. Immunol Cell Biol (2010) 1.08

The role of IL-27 in the development of T-cell responses during parasitic infections. Immunol Rev (2004) 1.06

Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses. J Virol (2013) 1.05

Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc Natl Acad Sci U S A (2011) 1.05

TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. Blood (2010) 1.01

Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma. Int Immunol (2006) 1.01

Innate lymphoid cells and allergic inflammation. Curr Opin Immunol (2013) 1.00

New insights into basophil biology: initiators, regulators, and effectors of type 2 inflammation. Ann N Y Acad Sci (2011) 1.00

Lymph node hypertrophy following Leishmania major infection is dependent on TLR9. J Immunol (2011) 1.00

Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection. J Immunol (2012) 1.00

New lessons from old pathogens: what parasitic infections have taught us about the role of nuclear factor-kappaB in the regulation of immunity. Immunol Rev (2004) 0.99

SnapShot: innate lymphoid cells. Immunity (2013) 0.99

Hookworm excretory/secretory products induce interleukin-4 (IL-4)+ IL-10+ CD4+ T cell responses and suppress pathology in a mouse model of colitis. Infect Immun (2013) 0.98

Adaptation of a nematode parasite to living within the mammalian epithelium. J Exp Zool A Comp Exp Biol (2005) 0.96

IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD. Int Immunol (2008) 0.95

B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses. J Immunol (2006) 0.94

Functional heterogeneity in the basophil cell lineage. Adv Immunol (2012) 0.92

Anatomical localization of commensal bacteria in immune cell homeostasis and disease. Immunol Rev (2014) 0.92

Forum: Immunology: Allergy challenged. Nature (2012) 0.90

Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection. J Immunol (2014) 0.89

Cutting edge: Helminth infection induces IgE in the absence of mu- or delta-chain expression. J Immunol (2008) 0.89

Maintaining diplomatic relations between mammals and beneficial microbial communities. Sci Signal (2009) 0.88

IL-31-IL-31R interactions limit the magnitude of Th2 cytokine-dependent immunity and inflammation following intestinal helminth infection. J Immunol (2009) 0.88

New friendships and old feuds: relationships between innate lymphoid cells and microbial communities. Immunol Cell Biol (2013) 0.85

NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS. J Neuroimmunol (2010) 0.84

Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. J Immunol (2005) 0.84

Immunity at the barriers. Eur J Immunol (2013) 0.78

Immunology. Rebuilding the thymus. Science (2012) 0.78

Chemiluminescence-based detection of gastrointestinal malignancies. Luminescence (2009) 0.77

Experimental Leishmania major infection suppresses HIV-1 DNA vaccine induced cellular immune response. Cells Tissues Organs (2004) 0.76

Special issue: translatability of helminth therapy. Int J Parasitol (2013) 0.76

The quiescin sulfhydryl oxidase (hQSOX1b) tunes the expression of resistin-like molecule alpha (RELM-α or mFIZZ1) in a wheat germ cell-free extract. PLoS One (2013) 0.76

Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity. PLoS Pathog (2017) 0.75

The influence of commensal bacteria-derived signals on basophil-associated allergic inflammation. Gut Microbes (2012) 0.75

David Artis: Fear no worm. Interview by Amy Maxmen. J Exp Med (2009) 0.75

O-003 Understanding the Relevance of Whole Exome Sequencing Identified Variants in Patients with Very Early-Onset-IBD. Inflamm Bowel Dis (2016) 0.75

Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis. Inflamm Bowel Dis (2017) 0.75

Innate immunity. Curr Opin Immunol (2010) 0.75