Published in J Membr Biol on February 01, 1990
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Optical imaging of Ca2+-evoked fluid secretion by murine nasal submucosal gland serous acinar cells. J Physiol (2007) 0.92
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An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum. J Biol Chem (2010) 0.76
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med (2005) 10.39
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Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest (2002) 4.97
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CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol (1994) 4.62
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Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem (2003) 4.40
Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature (2005) 4.20
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Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain (2010) 3.95
Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J (2004) 3.80
Green fluorescent protein as a noninvasive intracellular pH indicator. Biophys J (1998) 3.61
Determinants of the translational mobility of a small solute in cell cytoplasm. J Cell Biol (1993) 3.46
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest (1997) 3.45
Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem (2000) 3.29
Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy. J Gen Physiol (2004) 3.10
Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem (1998) 3.00
Crowding effects on diffusion in solutions and cells. Annu Rev Biophys (2008) 3.00
Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem (1999) 2.91
Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis. Kidney Int (2006) 2.89
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Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice. Proc Natl Acad Sci U S A (1998) 2.73
Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry. J Cell Biol (1991) 2.73
Differentiated structure and function of cultures from human tracheal epithelium. Am J Physiol (1992) 2.68
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem (2010) 2.66
Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J (1999) 2.59
Aquaporin 4 and neuromyelitis optica. Lancet Neurol (2012) 2.58
Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem (1997) 2.56
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J Cell Sci (1995) 2.55
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci (2005) 2.48
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol (2012) 2.45
Green fluorescent protein-based halide indicators with improved chloride and iodide affinities. FEBS Lett (2001) 2.38
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Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci U S A (1995) 2.37
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Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol (2005) 2.32
Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro. Mol Cell (1998) 2.31
Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. J Biol Chem (2003) 2.25
Culture and transformation of human airway epithelial cells. Am J Physiol (1995) 2.22
Localization of the CHIP28 water channel in rat kidney. Am J Physiol (1992) 2.17
Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol (2002) 2.16
The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J Biol Chem (1996) 2.16
Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J Cell Biol (1998) 2.12
Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proc Natl Acad Sci U S A (2001) 2.10
Altered fluid transport across airway epithelium in cystic fibrosis. Science (1993) 2.09
Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem (2005) 2.08
Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. FASEB J (2006) 2.07
Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest (2000) 2.07
Aquaporins and cell migration. Pflugers Arch (2007) 2.02
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Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. J Biol Chem (2001) 1.99
CFTR: folding, misfolding and correcting the ΔF508 conformational defect. Trends Mol Med (2011) 1.99
Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol (2003) 1.99
Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem (2011) 1.98
K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods (2005) 1.98
Analysis of fluorophore diffusion by continuous distributions of diffusion coefficients: application to photobleaching measurements of multicomponent and anomalous diffusion. Biophys J (1998) 1.95
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A (2000) 1.94
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci (2004) 1.90
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem (2002) 1.89
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. J Clin Invest (1998) 1.87
Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.87
Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium. Proc Natl Acad Sci U S A (1985) 1.87
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A (1998) 1.85
Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem (1992) 1.85
Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Mol Pharmacol (2007) 1.85
Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol (1993) 1.84
Three-dimensional organization of a human water channel. Nature (1997) 1.83
Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am J Physiol (1996) 1.82
Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH. J Clin Invest (2001) 1.80
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol (2005) 1.80
Cytoplasmic viscosity near the cell plasma membrane: translational diffusion of a small fluorescent solute measured by total internal reflection-fluorescence photobleaching recovery. Biophys J (1996) 1.79
Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. J Biol Chem (2002) 1.79
Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J Cell Sci (1997) 1.78
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides. Bioorg Med Chem (2008) 1.75
Transepithelial transport by pulmonary alveolar type II cells in primary culture. Proc Natl Acad Sci U S A (1982) 1.75
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways. FASEB J (2004) 1.75
Second messengers regulate endosomal acidification in Swiss 3T3 fibroblasts. J Cell Biol (1992) 1.74
Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. FASEB J (2006) 1.72
Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity. Biophys J (1990) 1.72
Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol (2011) 1.72
Inhibition of Ca2+-activated Cl- channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea. FASEB J (2010) 1.71
AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience (2009) 1.70
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem (2000) 1.70
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am J Physiol (1995) 1.69
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions. Mol Biol Cell (2006) 1.69
New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience (2004) 1.69
Direct measurement of trans-Golgi pH in living cells and regulation by second messengers. J Biol Chem (1995) 1.68
Impaired hearing in mice lacking aquaporin-4 water channels. J Biol Chem (2001) 1.68
Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists. Am J Physiol Cell Physiol (2001) 1.68
Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport. J Clin Invest (1996) 1.68
Simultaneous optical measurement of osmotic and diffusional water permeability in cells and liposomes. Biochemistry (1989) 1.68
Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J (2004) 1.68
Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain (2008) 1.67
The aqueous pore in the red cell membrane: band 3 as a channel for anions, cations, nonelectrolytes, and water. Ann N Y Acad Sci (1983) 1.66
New drug targets for cholera therapy. Trends Pharmacol Sci (2005) 1.64
cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units. J Biol Chem (1995) 1.62
Aquaporin-3 facilitates epidermal cell migration and proliferation during wound healing. J Mol Med (Berl) (2007) 1.62