Published in PLoS One on January 24, 2013
Lacritin and the tear proteome as natural replacement therapy for dry eye. Exp Eye Res (2013) 0.87
Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology. Biochim Biophys Acta (2014) 0.84
Proteomic analysis of pure human airway gland mucus reveals a large component of protective proteins. PLoS One (2015) 0.79
The importance of the Pseudomonas aeruginosa type III secretion system in epithelium traversal depends upon conditions of host susceptibility. Infect Immun (2015) 0.79
Cytotoxic activity and degradation patterns of structural proteins by corneal isolates of Acanthamoeba spp. Graefes Arch Clin Exp Ophthalmol (2014) 0.77
Co-regulation of Dectin-1 and TLR2 in inflammatory response of human corneal epithelial cells induced by Aspergillus fumigates. Int J Ophthalmol (2016) 0.76
Small leucine-rich repeat proteoglycans in corneal inflammation and wound healing. Exp Eye Res (2016) 0.75
Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model. BMC Med (2017) 0.75
The small leucine-rich repeat proteoglycans in tissue repair and atherosclerosis. J Intern Med (2015) 0.75
Proteomics in the Study of Bacterial Keratitis. Proteomes (2015) 0.75
Lumican overexpression exacerbates lipopolysaccharide-induced renal injury in mice. Mol Med Rep (2015) 0.75
The role of Syk signaling in antifungal innate immunity of human corneal epithelial cells. BMC Ophthalmol (2015) 0.75
Macrophage physiology in the eye. Pflugers Arch (2017) 0.75
Small leucine rich proteoglycans, a novel link to osteoclastogenesis. Sci Rep (2017) 0.75
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol (2010) 24.08
Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol (2003) 10.29
Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol (1998) 3.78
Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat Rev Immunol (2003) 3.74
IL-12 family cytokines: immunological playmakers. Nat Immunol (2012) 3.12
Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stroma. Invest Ophthalmol Vis Sci (2000) 2.10
Corneal response to Pseudomonas aeruginosa infection. Prog Retin Eye Res (2004) 2.09
The molecular basis of corneal transparency. Exp Eye Res (2010) 2.08
Regulation of the antimicrobial response by NLR proteins. Immunity (2011) 2.04
Pseudomonas aeruginosa infection and inflammation during contact lens wear: a review. Optom Vis Sci (2007) 1.90
Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Invest Ophthalmol Vis Sci (2005) 1.88
Role of lumican in the corneal epithelium during wound healing. J Biol Chem (2000) 1.85
TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. J Immunol (2010) 1.70
Regulation of endotoxin-induced keratitis by PECAM-1, MIP-2, and toll-like receptor 4. Invest Ophthalmol Vis Sci (2002) 1.46
CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis. J Leukoc Biol (2006) 1.44
Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest Ophthalmol Vis Sci (2005) 1.37
Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model. Invest Ophthalmol Vis Sci (2003) 1.31
The pathogenesis of bacterial keratitis: studies with Pseudomonas aeruginosa. Clin Exp Optom (2002) 1.30
Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis. Infect Immun (2007) 1.27
Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2005) 1.26
A novel role of the lumican core protein in bacterial lipopolysaccharide-induced innate immune response. J Biol Chem (2007) 1.26
Differential expression of inflammatory and fibrogenic genes and their regulation by NF-kappaB inhibition in a mouse model of chronic colitis. J Immunol (2007) 1.20
Pseudomonas keratitis. The role of an uncharacterized exoprotein, protease IV, in corneal virulence. Invest Ophthalmol Vis Sci (1996) 1.20
TLR4 is required for host resistance in Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2006) 1.20
Focus on molecules: lumican. Exp Eye Res (2005) 1.19
Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1. J Biol Chem (2007) 1.18
Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin. J Biol Chem (2009) 1.13
Infectious keratitis following keratoplasty. Surv Ophthalmol (2007) 1.12
ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival. J Immunol (2012) 1.06
High expression of chemokines Gro-alpha (CXCL-1), IL-8 (CXCL-8), and MCP-1 (CCL-2) in inflamed human corneas in vivo. Arch Ophthalmol (2003) 1.02
Infectious keratitis after photorefractive keratectomy in the United States army and navy. Ophthalmology (2006) 1.02
Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection. Microbes Infect (2010) 0.99
Role of neutrophils, MyD88-mediated neutrophil recruitment, and complement in antibody-mediated defense against Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci (2009) 0.98
Role of innate and adaptive immunity in the pathogenesis of keratitis. Ocul Immunol Inflamm (2005) 0.97
Role of IL-12 and IFN-gamma in Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci (2002) 0.96
Microbial keratitis. Br J Ophthalmol (2003) 0.94
Reviews for immune privilege in the year 2010: immune privilege and infection. Ocul Immunol Inflamm (2010) 0.93
Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient. J Leukoc Biol (2010) 0.86
The Clinical and Cellular Basis of Contact Lens-related Corneal Infections: A Review. Clin Ophthalmol (2008) 0.84
Contribution of the cornea to cytokine levels in the whole eye induced during the early phase of Pseudomonas aeruginosa challenge. Immunol Cell Biol (2005) 0.84
Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity. J Biol Chem (2012) 0.84
Bilateral bacterial keratitis in three patients following photorefractive keratectomy. J Refract Surg (2007) 0.77
MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology (2008) 3.29
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas. Proc Natl Acad Sci U S A (2009) 3.25
A murine model of chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-kappa B. Gastroenterology (2003) 2.53
Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun (2009) 2.05
Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm Bowel Dis (2007) 1.94
Reduced expression of the small leucine-rich proteoglycans, lumican, and decorin is associated with poor outcome in node-negative invasive breast cancer. Clin Cancer Res (2003) 1.67
A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice. J Biol Chem (2002) 1.64
Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling. Invest Ophthalmol Vis Sci (2005) 1.37
An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis. Hum Mol Genet (2011) 1.29
A novel role of the lumican core protein in bacterial lipopolysaccharide-induced innate immune response. J Biol Chem (2007) 1.26
Subnormal cytokine profile in the tear fluid of keratoconus patients. PLoS One (2011) 1.23
Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: implications in the cornea. Exp Eye Res (2004) 1.22
Differential expression of inflammatory and fibrogenic genes and their regulation by NF-kappaB inhibition in a mouse model of chronic colitis. J Immunol (2007) 1.20
Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin. J Biol Chem (2009) 1.13
Neonatal corneal stromal development in the normal and lumican-deficient mouse. Invest Ophthalmol Vis Sci (2003) 1.10
Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells. PLoS One (2008) 1.05
Chronic caloric restriction induces forestomach hypertrophy with enhanced ghrelin levels during aging. Peptides (2007) 1.02
Transforming growth factor-β signaling pathway activation in Keratoconus. Am J Ophthalmol (2011) 1.00
Fibromodulin regulates collagen fibrillogenesis during peripheral corneal development. Dev Dyn (2010) 0.98
Differential gene expression patterns of the developing and adult mouse cornea compared to the lens and tendon. Exp Eye Res (2008) 0.96
Sphere formation from corneal keratocytes and phenotype specific markers. Exp Eye Res (2011) 0.94
The keratoconus corneal proteome: loss of epithelial integrity and stromal degeneration. J Proteomics (2013) 0.94
Extracellular matrix protein lumican regulates inflammation in a mouse model of colitis. Inflamm Bowel Dis (2011) 0.90
Neonatal development of the corneal stroma in wild-type and lumican-null mice. Invest Ophthalmol Vis Sci (2006) 0.89
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy. Invest Ophthalmol Vis Sci (2013) 0.88
Aging changes of mouse corneal endothelium and Descemet's membrane. Exp Eye Res (2006) 0.87
Cryopreservation and lentiviral-mediated genetic modification of human primary cultured corneal endothelial cells. Invest Ophthalmol Vis Sci (2007) 0.86
Proteome profiling of wild type and lumican-deficient mouse corneas. J Proteomics (2011) 0.85
Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity. J Biol Chem (2012) 0.84
A novel antimicrobial peptidoglycan recognition protein in the cornea. Invest Ophthalmol Vis Sci (2009) 0.83
Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development. Am J Pathol (2011) 0.81
A cellular model for the investigation of Fuchs' endothelial corneal dystrophy. Exp Eye Res (2011) 0.79
Proteomics of human aqueous humor. OMICS (2015) 0.78
Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype. J Control Release (2011) 0.77