Published in Proc Natl Acad Sci U S A on December 15, 2009
EMT and dissemination precede pancreatic tumor formation. Cell (2012) 9.27
Eyes wide open: a critical review of sphere-formation as an assay for stem cells. Cell Stem Cell (2011) 3.55
Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell (2012) 3.36
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development (2011) 3.11
Organoid models of human and mouse ductal pancreatic cancer. Cell (2014) 2.99
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J (2013) 2.24
Beta-cell growth and regeneration: replication is only part of the story. Diabetes (2010) 1.92
Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas. Development (2011) 1.89
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A (2010) 1.84
Islet β cell mass in diabetes and how it relates to function, birth, and death. Ann N Y Acad Sci (2013) 1.84
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development (2013) 1.83
Pancreatic ductal cells in development, regeneration, and neoplasia. J Clin Invest (2011) 1.80
Extensive pancreas regeneration following acinar-specific disruption of Xbp1 in mice. Gastroenterology (2011) 1.72
Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation. Am J Physiol Gastrointest Liver Physiol (2012) 1.67
Tracking adult stem cells. EMBO Rep (2011) 1.56
Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells. Environ Health Perspect (2012) 1.53
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med (2014) 1.47
Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing β-cells. Development (2011) 1.36
Facultative stem cells in liver and pancreas: fact and fancy. Dev Dyn (2011) 1.32
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis. Genes Dev (2013) 1.28
Direct reprogramming by oncogenic Ras and Myc. Proc Natl Acad Sci U S A (2013) 1.26
Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease. Cell Stem Cell (2014) 1.21
Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol (2012) 1.21
Progenitor cell domains in the developing and adult pancreas. Cell Cycle (2011) 1.20
Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel. Proc Natl Acad Sci U S A (2013) 1.20
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. Elife (2013) 1.19
Heterogeneity and targeting of pancreatic cancer stem cells. Clin Cancer Res (2012) 1.18
Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proc Natl Acad Sci U S A (2011) 1.17
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes. J Clin Endocrinol Metab (2015) 1.07
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. Dev Biol (2011) 1.06
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Dev Biol (2012) 1.06
Aldehyde dehydrogenase 1A1 in stem cells and cancer. Oncotarget (2016) 1.06
Analysis of the tumor-initiating and metastatic capacity of PDX1-positive cells from the adult pancreas. Proc Natl Acad Sci U S A (2014) 1.03
Biological and clinical relevance of stem cells in pancreatic adenocarcinoma. J Gastroenterol Hepatol (2012) 1.00
Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells. PLoS One (2013) 1.00
Pancreatic beta-cells: from generation to regeneration. Semin Cell Dev Biol (2010) 0.97
The use of stem cells for pancreatic regeneration in diabetes mellitus. Nat Rev Endocrinol (2013) 0.97
Isolation, culture and genetic manipulation of mouse pancreatic ductal cells. Nat Protoc (2013) 0.97
Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunol Immunother (2014) 0.96
Regulation of Cellular Identity in Cancer. Dev Cell (2015) 0.96
Severely fibrotic pancreases from young patients with chronic pancreatitis: evidence for a ductal origin of islet neogenesis. Acta Diabetol (2011) 0.95
Regulation of acinar cell function in the pancreas. Curr Opin Gastroenterol (2010) 0.93
Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer. Cancer Res (2013) 0.92
Stem cells versus plasticity in liver and pancreas regeneration. Nat Cell Biol (2016) 0.92
Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways. Prog Mol Biol Transl Sci (2010) 0.91
Self-renewal and multilineage differentiation of mouse dental epithelial stem cells. Stem Cell Res (2013) 0.90
Bmi1 is required for regeneration of the exocrine pancreas in mice. Gastroenterology (2012) 0.88
Pancreatic cancer stem cells: new insights and perspectives. J Gastroenterol (2011) 0.87
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature (2016) 0.87
Aldh1-expressing endocrine progenitor cells regulate secondary islet formation in larval zebrafish pancreas. PLoS One (2013) 0.87
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Dev Biol (2012) 0.87
A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. Cell Syst (2016) 0.86
Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice. Purinergic Signal (2013) 0.86
Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer. Pancreatology (2013) 0.86
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development (2015) 0.86
Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. Sci Rep (2015) 0.85
In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice. Stem Cells Dev (2014) 0.85
Sox9: a master regulator of the pancreatic program. Rev Diabet Stud (2014) 0.84
The GCTM-5 epitope associated with the mucin-like glycoprotein FCGBP marks progenitor cells in tissues of endodermal origin. Stem Cells (2012) 0.84
Inflammation increases cells expressing ZSCAN4 and progenitor cell markers in the adult pancreas. Am J Physiol Gastrointest Liver Physiol (2013) 0.84
The quest for tissue stem cells in the pancreas and other organs, and their application in beta-cell replacement. Rev Diabet Stud (2010) 0.84
Label-retaining cells in the adult murine salivary glands possess characteristics of adult progenitor cells. PLoS One (2014) 0.83
A concise review on the current understanding of pancreatic cancer stem cells. J Cancer Stem Cell Res (2015) 0.82
Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development. Dev Biol (2014) 0.82
Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro. Stem Cells Dev (2015) 0.82
Centroacinar Cells Are Progenitors That Contribute to Endocrine Pancreas Regeneration. Diabetes (2015) 0.82
Potential pathways to restore β-cell mass: pluripotent stem cells, reprogramming, and endogenous regeneration. Curr Diab Rep (2011) 0.82
Dicer regulates differentiation and viability during mouse pancreatic cancer initiation. PLoS One (2014) 0.82
A quantitative assay for insulin-expressing colony-forming progenitors. J Vis Exp (2011) 0.82
Pancreatic cyst development: insights from von Hippel-Lindau disease. Cilia (2013) 0.81
Reprogramming Mouse Cells With a Pancreatic Duct Phenotype to Insulin-Producing β-Like Cells. Endocrinology (2015) 0.81
A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics. Dis Model Mech (2015) 0.81
Molecular imaging in tracking tumor stem-like cells. J Biomed Biotechnol (2012) 0.81
Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate. PLoS One (2015) 0.81
Stem cell-based approaches for the treatment of diabetes. Stem Cells Int (2011) 0.81
ALDH expression characterizes G1-phase proliferating beta cells during pregnancy. PLoS One (2014) 0.81
Making β cells from adult cells within the pancreas. Curr Diab Rep (2013) 0.81
Proliferating pancreatic beta-cells upregulate ALDH. Histochem Cell Biol (2014) 0.81
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol (2014) 0.80
Pancreatic duct glands (PDGs) are a progenitor compartment responsible for pancreatic ductal epithelial repair. Stem Cell Res (2015) 0.80
Stem cell marker-positive stellate cells and mast cells are reduced in benign-appearing bladder tissue in patients with urothelial carcinoma. Virchows Arch (2014) 0.80
Modeling pancreatic cancer with organoids. Trends Cancer (2016) 0.79
Retinoid signaling in pancreatic cancer, injury and regeneration. PLoS One (2011) 0.79
β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion. Cell Reprogram (2014) 0.79
Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement. Transplantation (2016) 0.79
Is stage-specific embryonic antigen 4 a marker for human ductal stem/progenitor cells? Biores Open Access (2012) 0.79
Development and regeneration in the endocrine pancreas. ISRN Endocrinol (2012) 0.79
Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biol (2015) 0.79
Purified human pancreatic duct cell culture conditions defined by serum-free high-content growth factor screening. PLoS One (2012) 0.78
Advances in acute and chronic pancreatitis: from development to inflammation and repair. Gastroenterology (2012) 0.78
Centroacinar cells: At the center of pancreas regeneration. Dev Biol (2016) 0.78
Chondroitin sulfate proteoglycan CSPG4 as a novel hypoxia-sensitive marker in pancreatic tumors. PLoS One (2014) 0.78
A red-shifted fluorescent substrate for aldehyde dehydrogenase. Nat Commun (2014) 0.78
Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer. Oncogene (2015) 0.78
A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm). Am J Cancer Res (2016) 0.77
ALDH1B1 links alcohol consumption and diabetes. Biochem Biophys Res Commun (2015) 0.77
Cells of origin of pancreatic neoplasms. Surg Today (2017) 0.77
The impact of hypoxia in pancreatic cancer invasion and metastasis. Hypoxia (Auckl) (2014) 0.76
Concise reviews: In vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors. Stem Cells (2015) 0.76
Adult tissue sources for new β cells. Transl Res (2013) 0.76
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell (2007) 22.89
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature (2004) 16.56
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature (2008) 16.21
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol (2008) 10.60
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell (2008) 8.57
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell (2003) 5.36
Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev Cell (2007) 4.90
A multipotent progenitor domain guides pancreatic organogenesis. Dev Cell (2007) 4.13
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A (2008) 4.01
Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci U S A (1999) 3.91
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 3.73
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development (2005) 3.57
In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia. Gastroenterology (2007) 3.41
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell (2005) 3.15
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes (2001) 2.95
Hedgehog signaling is required for effective regeneration of exocrine pancreas. Gastroenterology (2008) 2.71
Identification of a primitive brain-derived neural stem cell population based on aldehyde dehydrogenase activity. Stem Cells (2005) 2.67
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev (2009) 2.57
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev Biol (2005) 2.13
A CD133-expressing murine liver oval cell population with bilineage potential. Stem Cells (2007) 1.87
Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS. Proc Natl Acad Sci U S A (2006) 1.77
Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by flow cytometric cell sorting. Gastroenterology (2006) 1.74
Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development. Dev Dyn (2005) 1.70
Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting. Diabetes (2004) 1.59
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis. Proc Natl Acad Sci U S A (2009) 1.56
Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development (2006) 1.50
Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems. Blood (2008) 1.45
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells. PLoS One (2008) 1.24
Primary explant cultures of adult and embryonic pancreas. Methods Mol Med (2005) 1.16
Differentiation and proliferation of endocrine cells in the regenerating rat pancreas after 90% pancreatectomy. Arch Histol Cytol (2003) 1.13
Close association of centroacinar/ductular and insular cells in the rat pancreas. Histol Histopathol (1986) 1.01
Production of neurospheres from CNS tissue. Methods Mol Biol (2008) 1.01
Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin. Ann Anat (2003) 1.00
Minireview: pancreatic progenitor cells--recent studies. Endocrinology (2008) 0.99
The importance of the centroacinar region in cerulein-induced mouse pancreatic growth. Scand J Gastroenterol (1992) 0.95
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (2008) 36.02
EMT and dissemination precede pancreatic tumor formation. Cell (2012) 9.27
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A (2007) 6.44
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell (2003) 5.36
Main-duct intraductal papillary mucinous neoplasms of the pancreas: clinical predictors of malignancy and long-term survival following resection. Ann Surg (2004) 5.09
Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg (2003) 4.86
SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A (2007) 4.19
Pancreatic ductal adenocarcinoma: long-term survival does not equal cure. Surgery (2012) 3.87
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development (2005) 3.57
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology (2005) 3.56
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proc Natl Acad Sci U S A (2008) 3.43
In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia. Gastroenterology (2007) 3.41
Perioperative CA19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma. J Clin Oncol (2006) 3.37
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res (2006) 3.06
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mech Dev (2006) 3.02
Branch-duct intraductal papillary mucinous neoplasms: observations in 145 patients who underwent resection. Gastroenterology (2007) 2.96
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest (2007) 2.92
Hedgehog signaling is required for effective regeneration of exocrine pancreas. Gastroenterology (2008) 2.71
Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells. Cancer Res (2005) 2.64
Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish. Dev Biol (2007) 2.62
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev (2009) 2.57
Mucinous cystic neoplasm of the pancreas is not an aggressive entity: lessons from 163 resected patients. Ann Surg (2008) 2.45
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol (2003) 2.41
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev (2010) 2.37
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest (2002) 2.28
Nonapical symmetric divisions underlie horizontal cell layer formation in the developing retina in vivo. Neuron (2007) 2.25
Implications and cost of pancreatic leak following distal pancreatic resection. Arch Surg (2006) 2.25
Incidental pancreatic cysts: do we really know what we are watching? Pancreatology (2010) 2.22
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development (2004) 2.21
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network. Cancer Discov (2011) 2.14
Viral 2A peptides allow expression of multiple proteins from a single ORF in transgenic zebrafish embryos. Genesis (2007) 2.12
Plectin-1 as a novel biomarker for pancreatic cancer. Clin Cancer Res (2010) 2.03
Targeting of amacrine cell neurites to appropriate synaptic laminae in the developing zebrafish retina. Development (2005) 2.00
Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw (2012) 1.97
Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes. Gut (2011) 1.94
Pancreatic cancer. Curr Probl Cancer (2002) 1.92
Mucin-producing neoplasms of the pancreas: an analysis of distinguishing clinical and epidemiologic characteristics. Clin Gastroenterol Hepatol (2009) 1.90
Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia. Gastroenterology (2009) 1.78
Implications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomes. Arch Surg (2011) 1.78
FOLFIRINOX in locally advanced pancreatic cancer: the Massachusetts General Hospital Cancer Center experience. Oncologist (2013) 1.76
Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas. Clin Cancer Res (2006) 1.75
FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev Biol (2003) 1.73
Implications and management of pancreatic fistulas following pancreaticoduodenectomy: the Massachusetts General Hospital experience. Arch Surg (2008) 1.72
Debridement and closed packing for sterile or infected necrotizing pancreatitis: insights into indications and outcomes in 167 patients. Ann Surg (2008) 1.69
851 resected cystic tumors of the pancreas: a 33-year experience at the Massachusetts General Hospital. Surgery (2012) 1.68
Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol (2007) 1.68
Gal4/UAS transgenic tools and their application to zebrafish. Zebrafish (2008) 1.68
Current trends in pancreatic cystic neoplasms. Arch Surg (2009) 1.68
Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis. Ann Surg (2003) 1.66
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev Dyn (2002) 1.61
Diminished beta-cell replication contributes to reduced beta-cell mass in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol (2005) 1.54
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol (2009) 1.52
Pancreatic adenocarcinoma. J Natl Compr Canc Netw (2010) 1.52
Middle pancreatectomy: indications, short- and long-term operative outcomes. Ann Surg (2007) 1.46
Polyswitch lentivectors: "all-in-one" lentiviral vectors for drug-inducible gene expression, live selection, and recombination cloning. Hum Gene Ther (2011) 1.46
Metastatic tumors in the pancreas in the modern era. J Am Coll Surg (2010) 1.45
Evolving patterns in the detection and outcomes of pancreatic neuroendocrine neoplasms: the Massachusetts General Hospital experience from 1977 to 2005. Arch Surg (2007) 1.45
Improved contemporary surgical management of insulinomas: a 25-year experience at the Massachusetts General Hospital. Ann Surg (2008) 1.45
Zebrafish models for cancer. Annu Rev Pathol (2011) 1.41
Evolution of the Whipple procedure at the Massachusetts General Hospital. Surgery (2012) 1.40
Beta cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo. Proc Natl Acad Sci U S A (2007) 1.39
Pancreatic fistula rates after 462 distal pancreatectomies: staplers do not decrease fistula rates. J Gastrointest Surg (2008) 1.38
Validation of a postresection pancreatic adenocarcinoma nomogram for disease-specific survival. J Clin Oncol (2005) 1.37
Oncogenic KRAS induces progenitor cell expansion and malignant transformation in zebrafish exocrine pancreas. Gastroenterology (2008) 1.36
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Dev Biol (2004) 1.36
Predicting resectability of periampullary cancer with three-dimensional computed tomography. J Gastrointest Surg (2004) 1.34
Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology (2013) 1.34
A case of mistaken identity? Nonductal origins of pancreatic "ductal" cancers. Cancer Cell (2007) 1.32
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas. Mech Dev (2004) 1.31
Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology (2003) 1.28
The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss. Proc Natl Acad Sci U S A (2003) 1.27
Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Dev Biol (2004) 1.26
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes Dev (2008) 1.26
FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol (2008) 1.26
FGF10 signaling controls stomach morphogenesis. Dev Biol (2006) 1.23
Ribosomal biogenesis genes play an essential and p53-independent role in zebrafish pancreas development. Development (2012) 1.22
Global genomic analysis of intraductal papillary mucinous neoplasms of the pancreas reveals significant molecular differences compared to ductal adenocarcinoma. Ann Surg (2009) 1.17
Epithelial cell guidance by self-generated EGF gradients. Integr Biol (Camb) (2012) 1.17
Primary explant cultures of adult and embryonic pancreas. Methods Mol Med (2005) 1.16
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Dev Biol (2007) 1.15
Distal pancreatectomy with splenic preservation revisited. Surgery (2007) 1.14
Evidence for repatterning of the gastric fundic epithelium associated with Ménétrier's disease and TGFalpha overexpression. Gastroenterology (2005) 1.14
Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells. Gastroenterology (2002) 1.13
Surgery for small and asymptomatic branch-duct IPMNs. Ann Surg (2014) 1.13
Gene expression alterations in the non-neoplastic parenchyma adjacent to infiltrating pancreatic ductal adenocarcinoma. Mod Pathol (2005) 1.13
Early detection of sporadic pancreatic cancer: summative review. Pancreas (2015) 1.10
Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse. Diabetes (2008) 1.09
N0/N1, PNL, or LNR? The effect of lymph node number on accurate survival prediction in pancreatic ductal adenocarcinoma. J Gastrointest Surg (2012) 1.09
Pancreatic ductal morphogenesis and the Pdx1 homeodomain transcription factor. Mol Biol Cell (2009) 1.09
Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn (2003) 1.07
Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays. Oncogene (2004) 1.07
GeneSpeed: protein domain organization of the transcriptome. Nucleic Acids Res (2006) 1.07
Quality of life in pancreatic cancer: analysis by stage and treatment. J Gastrointest Surg (2008) 1.07
Added value of selected images embedded into radiology reports to referring clinicians. J Am Coll Radiol (2010) 1.05
Understanding hospital readmissions after pancreaticoduodenectomy: can we prevent them?: a 10-year contemporary experience with 1,173 patients at the Massachusetts General Hospital. J Gastrointest Surg (2013) 1.03
Sphere-forming assays for assessment of benign and malignant pancreatic stem cells. Methods Mol Biol (2013) 1.03