Published in N Engl J Med on May 24, 1990
Implementing guidelines in general practice care. Qual Health Care (1992) 6.39
Decisions near the end of life: professional views on life-sustaining treatments. Am J Public Health (1993) 4.27
Adoption of information technology enabled innovations by primary care physicians: model and questionnaire development. Proc Annu Symp Comput Appl Med Care (1994) 3.19
Clinical guidelines: their implementation in general practice. Br J Gen Pract (1995) 2.67
Evaluation of user acceptance of a clinical expert system. J Am Med Inform Assoc (1995) 2.55
Simple low back pain: rest or active exercise? Ann Rheum Dis (1993) 1.07
The Doctor's, the Druggist's, and the Detail Rep's Dance: Who leads, who follows? Can Fam Physician (1991) 1.06
Bayesian communication: a clinically significant paradigm for electronic publication. J Am Med Inform Assoc (2000) 0.88
Clinical guidelines. Report of a local initiative. Introduction. Occas Pap R Coll Gen Pract (1992) 0.85
Playing the cost-containment game. West J Med (1992) 0.75
The route to a national health policy lies through the states. Yale J Biol Med (1992) 0.75
Modifying physician practice patterns--reflections on past deeds. West J Med (1991) 0.75
Study on management of pediatric migraine by general practitioners in northern France. J Headache Pain (2009) 0.75
The effect on test ordering of informing physicians of the charges for outpatient diagnostic tests. N Engl J Med (1990) 9.74
The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. JAMA (1996) 17.62
Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med (1977) 8.24
Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation (1999) 8.17
Clinical prediction rules. Applications and methodological standards. N Engl J Med (1985) 7.72
Adverse outcomes of underuse of beta-blockers in elderly survivors of acute myocardial infarction. JAMA (1997) 7.42
The value of the autopsy in three medical eras. N Engl J Med (1983) 7.00
Contaminant blood cultures and resource utilization. The true consequences of false-positive results. JAMA (1991) 6.28
Forecasting coronary heart disease incidence, mortality, and cost: the Coronary Heart Disease Policy Model. Am J Public Health (1987) 6.21
A clinical prediction rule for delirium after elective noncardiac surgery. JAMA (1994) 5.92
Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments) Am J Respir Crit Care Med (1996) 5.82
The emerging role of "hospitalists" in the American health care system. N Engl J Med (1996) 5.40
The recent decline in mortality from coronary heart disease, 1980-1990. The effect of secular trends in risk factors and treatment. JAMA (1997) 5.36
The impact of a regulation restricting medical house staff working hours on the quality of patient care. JAMA (1993) 5.11
Inactivation of the sodium current in Myxicola giant axons. Evidence for coupling to the activation process. J Gen Physiol (1972) 4.92
Adult (not internal) medicine. Ann Intern Med (1997) 4.60
Quantitative description of sodium and potassium currents and computed action potentials in Myxicola giant axons. J Gen Physiol (1973) 4.44
Current- and voltage-clamped studies on Myxicola giant axons. Effect of tetrodotoxin. J Gen Physiol (1969) 4.36
Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as compared with dual-chamber pacing. Pacemaker Selection in the Elderly Investigators. N Engl J Med (1998) 4.22
Expected gains in life expectancy from various coronary heart disease risk factor modifications. Circulation (1991) 3.75
Comparative reproducibility and validity of systems for assessing cardiovascular functional class: advantages of a new specific activity scale. Circulation (1981) 3.74
The decline in ischemic heart disease mortality rates. An analysis of the comparative effects of medical interventions and changes in lifestyle. Ann Intern Med (1984) 3.71
Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am J Med (1989) 3.65
Evaluation of the patient with acute chest pain. N Engl J Med (2000) 3.42
Predicting bacteremia in hospitalized patients. A prospectively validated model. Ann Intern Med (1990) 3.31
Resuscitation preferences among patients with severe congestive heart failure: results from the SUPPORT project. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. Circulation (1998) 3.11
ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J (2009) 3.08
The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. Ann Intern Med (1995) 3.08
Development of the 'Activities of Daily Vision Scale'. A measure of visual functional status. Med Care (1992) 3.06
Effect of race on the presentation and management of patients with acute chest pain. Ann Intern Med (1993) 3.00
Rectification in instantaneous potassium current-voltage relations in Myxicola giant axons. J Physiol (1971) 2.84
Cost-effectiveness of cholesterol-lowering therapies according to selected patient characteristics. Ann Intern Med (2000) 2.71
Fate of cardiology research originally published in abstract form. N Engl J Med (1980) 2.67
Evaluation and outcome of emergency room patients with transient loss of consciousness. Am J Med (1982) 2.59
Correlates of early hospital readmission or death in patients with congestive heart failure. Am J Cardiol (1997) 2.55
Reorganizing an academic medical service: impact on cost, quality, patient satisfaction, and education. JAMA (1998) 2.53
Factors contributing to the hospitalization of patients with congestive heart failure. Am J Public Health (1997) 2.51
Ruling out acute myocardial infarction. A prospective multicenter validation of a 12-hour strategy for patients at low risk. N Engl J Med (1991) 2.47
Computation of impulse conduction in myelinated fibers; theoretical basis of the velocity-diameter relation. Biophys J (1968) 2.47
Patient and house officer attitudes on physician attire and etiquette. JAMA (1987) 2.44
Candidates for thrombolysis among emergency room patients with acute chest pain. Potential true- and false-positive rates. Ann Intern Med (1989) 2.43
Acutely injured patients with trauma in Massachusetts: differences in care and mortality, by insurance status. Am J Public Health (1994) 2.38
Preventability of emergent hospital readmission. Am J Med (1991) 2.35
A computer-derived protocol to aid in the diagnosis of emergency room patients with acute chest pain. N Engl J Med (1982) 2.28
Current separations in Myxicola giant axons. J Gen Physiol (1969) 2.28
Correlation between preoperative ischemia and major cardiac events after peripheral vascular surgery. N Engl J Med (1989) 2.28
Screening procedures in the asymptomatic adult. Comparison of physicians' recommendations, patients' desires, published guidelines, and actual practice. JAMA (1985) 2.20
Health values of the seriously ill. SUPPORT investigators. Ann Intern Med (1995) 2.14
Making medicine more scientific. Nature (1994) 2.11
A multivariate approach to the prediction of no-show behavior in a primary care center. Arch Intern Med (1982) 2.10
Preoperative assessment of patients with known or suspected coronary disease. N Engl J Med (1995) 2.09
The relationship of postoperative delirium with psychoactive medications. JAMA (1994) 2.09
Optimal management strategies for HIV-infected patients who present with cough or dyspnea: a cost-effective analysis. J Gen Intern Med (1992) 2.07
Supraventricular arrhythmia in patients having noncardiac surgery: clinical correlates and effect on length of stay. Ann Intern Med (1998) 2.04
Long-term cost-effectiveness of various initial monotherapies for mild to moderate hypertension. JAMA (1990) 2.01
Right heart catheterization and cardiac complications in patients undergoing noncardiac surgery: an observational study. JAMA (2001) 1.99
Impact of inter-physician communication on the effectiveness of medical consultations. Am J Med (1983) 1.98
Balancing risks and benefits: Primum non nocere is too simplistic. Pediatrics (2001) 1.96
Diagnostic yield of the autopsy in a university hospital and a community hospital. N Engl J Med (1988) 1.94
Improved visual function and attenuation of declines in health-related quality of life after cataract extraction. Arch Ophthalmol (1994) 1.93
Kinetics of channel gating in excitable membranes. Q Rev Biophys (1976) 1.93
The association of intraoperative factors with the development of postoperative delirium. Am J Med (1998) 1.92
Cost effectiveness of thrombolytic therapy with streptokinase in elderly patients with suspected acute myocardial infarction. N Engl J Med (1992) 1.92
Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med (2001) 1.88
Acute chest pain in the emergency room. Identification and examination of low-risk patients. Arch Intern Med (1985) 1.86
Risk assessment in cancer patients with fever and neutropenia: a prospective, two-center validation of a prediction rule. J Clin Oncol (1992) 1.86
A critical pathway for management of patients with acute chest pain who are at low risk for myocardial ischemia: recommendations and potential impact. Ann Intern Med (1997) 1.85
The effects of some ions on the membrane potential of the giant axon of Myxicola. J Cell Physiol (1968) 1.83
Risks of general anesthesia and elective operation in the hypertensive patient. Anesthesiology (1979) 1.83
Overestimation of clinical diagnostic performance caused by low necropsy rates. Qual Saf Health Care (2005) 1.82
Patient age and decisions to withhold life-sustaining treatments from seriously ill, hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment. Ann Intern Med (1999) 1.81
Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Ann Intern Med (1987) 1.81
Care of patients with a low probability of acute myocardial infarction. Cost effectiveness of alternatives to coronary-care-unit admission. N Engl J Med (1984) 1.80
Predictors of event-free survival after balloon aortic valvuloplasty. N Engl J Med (1991) 1.78
Leak current rectification in Myxicola giant axons. Constant field and constant conductance components. J Gen Physiol (1969) 1.76
Significance of post-cholecystectomy subhepatic fluid collections. Ann Surg (1983) 1.74
The impact of postoperative pain on the development of postoperative delirium. Anesth Analg (1998) 1.72
The autopsy as an outcome and performance measure. Evid Rep Technol Assess (Summ) (2002) 1.71
Quantitative description of the sodium conductance of the giant axon of Myxicola in terms of a generalized second-order variable. Biophys J (1975) 1.71
Initial conditions and the kinetics of the sodium conductance in Myxicola giant axons. II. Relaxation experiments. J Gen Physiol (1978) 1.70
HYPERPARATHYROIDISM IN SIBLINGS. Ann Surg (1936) 1.67
Evidence that hospital care for acute myocardial infarction has not contributed to the decline in coronary mortality between 1973-1974 and 1978-1979. Circulation (1982) 1.67
The permeability of the sodium channel in Myxicola to the alkali cations. J Gen Physiol (1976) 1.65
Cardiac troponin T as a marker for myocardial ischemia in patients seen at the emergency department for acute chest pain. Am Heart J (1999) 1.61
Appointment reminders to reduce no-show rates. A stratified analysis of their cost-effectiveness. JAMA (1983) 1.61
Ten commandments for effective consultations. Arch Intern Med (1983) 1.59
Performance of tests of significance based on stratification by a multivariate confounder score or by a propensity score. J Clin Epidemiol (1989) 1.58
Cost-effectiveness of routine coronary angiography after acute myocardial infarction. Circulation (1996) 1.58
Age-related differences in management of heart disease: a study of cardiac medication use in an older cohort. Pacemaker Selection in the Elderly (PASE) Investigators. J Am Geriatr Soc (1999) 1.58
Comorbidity as a correlate of length of stay for hospitalized patients with acute chest pain. J Gen Intern Med (1996) 1.56
Cost-effectiveness of a new short-stay unit to "rule out" acute myocardial infarction in low risk patients. J Am Coll Cardiol (1994) 1.55
Cost-effectiveness of captopril therapy after myocardial infarction. J Am Coll Cardiol (1995) 1.52
Surgical treatment of chronic pancreatitis. Am J Surg (1974) 1.50
Empiric comparison of multivariate analytic techniques: advantages and disadvantages of recursive partitioning analysis. J Chronic Dis (1984) 1.49
Triage decisions for emergency department patients with chest pain: do physicians' risk attitudes make the difference? J Gen Intern Med (1995) 1.49
Serum enzyme assays in the diagnosis of acute myocardial infarction. Recommendations based on a quantitative analysis. Ann Intern Med (1986) 1.48
Diagnostic advances v the value of the autopsy. 1912-1980. Arch Pathol Lab Med (1984) 1.48
Bleeding in outpatients treated with warfarin: relation to the prothrombin time and important remediable lesions. Am J Med (1989) 1.48