Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies.

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Published in Clin Cancer Res on February 19, 2013

Authors

Dong M Shin1, Hongzheng Zhang, Nabil F Saba, Amy Y Chen, Sreenivas Nannapaneni, A R M Ruhul Amin, Susan Müller, Melinda Lewis, Gabriel Sica, Scott Kono, Johann C Brandes, William J Grist, Rachel Moreno-Williams, Jonathan J Beitler, Sufi M Thomas, Zhengjia Chen, Hyung Ju C Shin, Jennifer R Grandis, Fadlo R Khuri, Zhuo Georgia Chen

Author Affiliations

1: Department of Hematology and Medical Oncology, Emory University School of Medicine Atlanta, Georgia 30322, USA.

Associated clinical trials:

Erlotinib Prevention of Oral Cancer (EPOC) | NCT00402779

Phase I/II Study of Chemoprevention With EGFR and COX-2 Inhibitor | NCT00314262

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