Published in Protein Sci on March 26, 2013
Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies. FEBS Lett (2013) 0.99
Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis. Proc Natl Acad Sci U S A (2013) 0.93
Mass spectrometry in studies of protein thiol chemistry and signaling: opportunities and caveats. Free Radic Biol Med (2014) 0.89
Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry. Proc Natl Acad Sci U S A (2013) 0.85
Measuring hydrogen exchange rates in invisible protein excited states. Proc Natl Acad Sci U S A (2014) 0.82
A new approach to measuring protein backbone protection with high spatial resolution using H/D exchange and electron capture dissociation. Anal Chem (2013) 0.79
Crucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study. J Biol Chem (2014) 0.78
Electron-capture dissociation and ion mobility mass spectrometry for characterization of the hemoglobin protein assembly. Protein Sci (2015) 0.77
Load-dependent destabilization of the γ-rotor shaft in FOF1 ATP synthase revealed by hydrogen/deuterium-exchange mass spectrometry. Proc Natl Acad Sci U S A (2016) 0.76
Changes in protein structure monitored by use of gas-phase hydrogen/deuterium exchange. Proteomics (2015) 0.75
DisProt 7.0: a major update of the database of disordered proteins. Nucleic Acids Res (2016) 0.75
Kinetics of Protein Complex Dissociation Studied by Hydrogen/Deuterium Exchange and Mass Spectrometry. Anal Chem (2015) 0.75
Evidence for an essential role of intradimer interaction in catalytic function of carnosine dipeptidase II using electrospray-ionization mass spectrometry. Protein Sci (2015) 0.75
Protein structural dynamics at the gas/water interface examined by hydrogen exchange mass spectrometry. Protein Sci (2015) 0.75
Are Charge-State Distributions a Reliable Tool Describing Molecular Ensembles of Intrinsically Disordered Proteins by Native MS? J Am Soc Mass Spectrom (2016) 0.75
Hydrogen exchange in proteins. Adv Protein Chem (1966) 7.02
Native mass spectrometry: a bridge between interactomics and structural biology. Nat Methods (2008) 3.11
Appendix 5. Nomenclature for peptide fragment ions (positive ions). Methods Enzymol (1990) 2.41
Investigation of intact protein complexes by mass spectrometry. Mass Spectrom Rev (2004) 2.39
Origin of asymmetric charge partitioning in the dissociation of gas-phase protein homodimers. J Am Chem Soc (2003) 2.15
Detection of multiple protein conformational ensembles in solution via deconvolution of charge-state distributions in ESI MS. Anal Chem (2001) 2.08
Solvent-induced conformational changes of polypeptides probed by electrospray-ionization mass spectrometry. Rapid Commun Mass Spectrom (1991) 2.06
Is apomyoglobin a molten globule? Structural characterization by NMR. J Mol Biol (1996) 2.02
Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars. Nat Rev Drug Discov (2012) 1.80
High resolution, high-throughput amide deuterium exchange-mass spectrometry (DXMS) determination of protein binding site structure and dynamics: utility in pharmaceutical design. J Cell Biochem Suppl (2001) 1.74
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry. Anal Chem (2009) 1.65
Structure and properties of alpha-synuclein and other amyloids determined at the amino acid level. Proc Natl Acad Sci U S A (2005) 1.65
Protein hydrogen exchange mechanism: local fluctuations. Protein Sci (2003) 1.63
Post-translational modifications differentially affect IgG1 conformation and receptor binding. Mol Cell Proteomics (2010) 1.59
Acid-induced unfolding of cytochrome c at different methanol concentrations: electrospray ionization mass spectrometry specifically monitors changes in the tertiary structure. Biochemistry (1997) 1.58
Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions. Expert Rev Proteomics (2011) 1.45
Estimates of protein surface areas in solution by electrospray ionization mass spectrometry. Anal Chem (2005) 1.42
Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein. Protein Sci (2002) 1.35
Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein. J Am Chem Soc (2009) 1.35
Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling. J Am Soc Mass Spectrom (2009) 1.33
Electron capture/transfer versus collisionally activated/induced dissociations: solo or duet? J Am Soc Mass Spectrom (2008) 1.31
H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach? Anal Chem (2009) 1.30
Do ionic charges in ESI MS provide useful information on macromolecular structure? J Am Soc Mass Spectrom (2008) 1.27
Equilibrium unfolding of proteins monitored by electrospray ionization mass spectrometry: distinguishing two-state from multi-state transitions. Rapid Commun Mass Spectrom (1998) 1.27
Epitope mapping by amide hydrogen/deuterium exchange coupled with immobilization of antibody, on-line proteolysis, liquid chromatography and mass spectrometry. Rapid Commun Mass Spectrom (2009) 1.27
Electron capture dissociation of electrosprayed protein ions for spatially resolved hydrogen exchange measurements. J Am Chem Soc (2008) 1.25
Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry. Biochemistry (2008) 1.18
Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches. Anal Chem (2008) 1.14
Gas-phase dissociation pathways of multiply charged peptide clusters. J Am Soc Mass Spectrom (2003) 1.09
Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization. Biochemistry (2011) 1.09
A chemometric approach to detection and characterization of multiple protein conformers in solution using electrospray ionization mass spectrometry. Anal Chem (2003) 1.08
Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein. Proteins (2010) 1.05
Noncanonical interactions between serum transferrin and transferrin receptor evaluated with electrospray ionization mass spectrometry. Proc Natl Acad Sci U S A (2010) 1.05
Epitope mapping of a 95 kDa antigen in complex with antibody by solution-phase amide backbone hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2011) 1.04
Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry. J Am Soc Mass Spectrom (2009) 1.04
ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements. J Am Soc Mass Spectrom (2011) 1.01
Automated hydrogen/deuterium exchange electron transfer dissociation high resolution mass spectrometry measured at single-amide resolution. J Am Soc Mass Spectrom (2011) 1.01
Assessment of metals in reconstituted metallothioneins by electrospray mass spectrometry. Anal Chem (1993) 1.00
Real-time hydrogen/deuterium exchange kinetics via supercharged electrospray ionization tandem mass spectrometry. Anal Chem (2010) 1.00
Highly asymmetric interactions between globin chains during hemoglobin assembly revealed by electrospray ionization mass spectrometry. Biochemistry (2003) 0.98
Co-populated conformational ensembles of beta2-microglobulin uncovered quantitatively by electrospray ionization mass spectrometry. J Biol Chem (2004) 0.96
Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry. Protein Sci (2002) 0.96
Charge-surface correlation in electrospray ionization of folded and unfolded proteins. Anal Chem (2011) 0.94
Dynamics of iron release from transferrin N-lobe studied by electrospray ionization mass spectrometry. Anal Chem (2001) 0.94
Compaction properties of an intrinsically disordered protein: Sic1 and its kinase-inhibitor domain. Biophys J (2011) 0.93
On the conformation-dependent neutralization theory and charging of individual proteins and their non-covalent complexes in the gas phase. J Mass Spectrom (2004) 0.92
Determination of the mechanism of action of anti-FasL antibody by epitope mapping and homology modeling. Biochemistry (2009) 0.92
Signal response of coexisting protein conformers in electrospray mass spectrometry. Anal Chem (2007) 0.92
Subunit disassembly and unfolding kinetics of hemoglobin studied by time-resolved electrospray mass spectrometry. Biochemistry (2004) 0.91
Metal-dependent folding and stability of nuclear hormone receptor DNA-binding domains. J Mol Biol (2002) 0.91
Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking. J Mol Recognit (2012) 0.90
Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry. Biochemistry (2012) 0.90
Compact conformations of α-synuclein induced by alcohols and copper. Proteins (2011) 0.89
Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry. Biochim Biophys Acta (2011) 0.89
Gas-phase interference-free analysis of protein ion charge-state distributions: detection of small-scale conformational transitions accompanying pepsin inactivation. Anal Chem (2007) 0.88
Impact of oxidation on protein therapeutics: conformational dynamics of intact and oxidized acid-β-glucocerebrosidase at near-physiological pH. Protein Sci (2010) 0.88
Structures of apomyoglobin's various acid-destabilized forms. Biochemistry (2001) 0.87
Hydrogen-deuterium exchange mass spectrometry reveals the interaction of Fenna-Matthews-Olson protein and chlorosome CsmA protein. Biochemistry (2011) 0.87
Detecting equilibrium cytochrome c folding intermediates by electrospray ionisation mass spectrometry: two partially folded forms populate the molten-globule state. Protein Sci (2002) 0.87
IL-1beta epitope mapping using site-directed mutagenesis and hydrogen-deuterium exchange mass spectrometry analysis. Biochemistry (2005) 0.87
Hydrogen/deuterium exchange mass spectrometry reveals specific changes in the local flexibility of plasminogen activator inhibitor 1 upon binding to the somatomedin B domain of vitronectin. Biochemistry (2012) 0.86
Symmetric behavior of hemoglobin alpha- and beta- subunits during acid-induced denaturation observed by electrospray mass spectrometry. Biochemistry (2007) 0.86
Hydrogen exchange kinetics of proteins in denaturants: a generalized two-process model. J Mol Biol (1999) 0.85
Electrospray ionization mass spectrometry of highly heterogeneous protein systems: protein ion charge state assignment via incomplete charge reduction. Anal Chem (2010) 0.84
Unfolding dynamics of a beta-sheet protein studied by mass spectrometry. J Mass Spectrom (1999) 0.84
Advanced mass spectrometry-based methods for the analysis of conformational integrity of biopharmaceutical products. Curr Pharm Biotechnol (2011) 0.84
Electrospray ionization-mass spectrometry conformational analysis of isolated domains of an intrinsically disordered protein. Biotechnol J (2011) 0.82
Studies of pH-dependent self-association of a recombinant form of arylsulfatase A with electrospray ionization mass spectrometry and size-exclusion chromatography. Anal Chem (2013) 0.80
Direct monitoring of heat-stressed biopolymers with temperature-controlled electrospray ionization mass spectrometry. Anal Chem (2011) 0.79
Mapping the protein-protein interface between a toxin and its cognate antitoxin from the bacterial pathogen Streptococcus pyogenes. Biochemistry (2011) 0.78
The emerging role of MS in structure elucidation of protein-nucleic acid complexes. Biochem Soc Trans (2008) 0.78
Crystallization and preliminary crystallographic analysis of a new crystal form of arylsulfatase A isolated from human placenta. Acta Crystallogr D Biol Crystallogr (2000) 0.76
H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach? Anal Chem (2009) 1.30
Do ionic charges in ESI MS provide useful information on macromolecular structure? J Am Soc Mass Spectrom (2008) 1.27
Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches. Anal Chem (2008) 1.14
Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics. Biotechnol Adv (2011) 1.07
Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein. Proteins (2010) 1.05
Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry. J Am Soc Mass Spectrom (2009) 1.04
Further unraveling the regulatory twist by elucidating metabolic coinducer-mediated CbbR-cbbI promoter interactions in Rhodopseudomonas palustris CGA010. J Bacteriol (2012) 0.92
Investigation of structure, dynamics and function of metalloproteins with electrospray ionization mass spectrometry. Anal Bioanal Chem (2006) 0.90
Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry. Biochim Biophys Acta (2011) 0.89
Pitfalls in protein quantitation using acid-catalyzed O18 labeling: hydrolysis-driven deamidation. Anal Chem (2011) 0.88
Gas-phase interference-free analysis of protein ion charge-state distributions: detection of small-scale conformational transitions accompanying pepsin inactivation. Anal Chem (2007) 0.88
Conformer-specific characterization of nonnative protein states using hydrogen exchange and top-down mass spectrometry. Proc Natl Acad Sci U S A (2013) 0.85
Emerging mass spectrometry-based approaches to probe protein-receptor interactions: focus on overcoming physiological barriers. Adv Drug Deliv Rev (2013) 0.84
Electrospray ionization mass spectrometry of highly heterogeneous protein systems: protein ion charge state assignment via incomplete charge reduction. Anal Chem (2010) 0.84
Unravelling the regulatory twist--regulation of CO2 fixation in Rhodopseudomonas palustris CGA010 mediated by atypical response regulator(s). Mol Microbiol (2011) 0.82
Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin. Biochemistry (2009) 0.81
Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin. Protein Expr Purif (2010) 0.81
Human serum transferrin: is there a link among autism, high oxalate levels, and iron deficiency anemia? Biochemistry (2013) 0.80
Biochemical and structural characterization of recombinant human serum transferrin from rice (Oryza sativa L.). J Inorg Biochem (2012) 0.80
Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate. Mol Pharm (2013) 0.80
Studies of pH-dependent self-association of a recombinant form of arylsulfatase A with electrospray ionization mass spectrometry and size-exclusion chromatography. Anal Chem (2013) 0.80
Direct monitoring of heat-stressed biopolymers with temperature-controlled electrospray ionization mass spectrometry. Anal Chem (2011) 0.79
A new approach to measuring protein backbone protection with high spatial resolution using H/D exchange and electron capture dissociation. Anal Chem (2013) 0.79
Regulatory twist and synergistic role of metabolic coinducer- and response regulator-mediated CbbR-cbbI interactions in Rhodopseudomonas palustris CGA010. J Bacteriol (2013) 0.78
Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis. Biochemistry (2008) 0.76
Assessing the iron delivery efficacy of transferrin in clinical samples by native electrospray ionization mass spectrometry. Analyst (2015) 0.75