Published in Proc Natl Acad Sci U S A on September 09, 2013
Applications of hydrogen/deuterium exchange MS from 2012 to 2014. Anal Chem (2014) 1.16
High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome. Proc Natl Acad Sci U S A (2015) 0.81
A synchrotron-based hydroxyl radical footprinting analysis of amyloid fibrils and prefibrillar intermediates with residue-specific resolution. Biochemistry (2014) 0.80
Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment. Mol Cell Proteomics (2017) 0.79
Quantitative protein topography analysis and high-resolution structure prediction using hydroxyl radical labeling and tandem-ion mass spectrometry (MS). Mol Cell Proteomics (2015) 0.79
Functional dynamics of hexameric helicase probed by hydrogen exchange and simulation. Biophys J (2014) 0.79
Structural characterization of semen coagulum-derived SEM1(86-107) amyloid fibrils that enhance HIV-1 infection. Biochemistry (2014) 0.79
Cytochrome c folds through foldon-dependent native-like intermediates in an ordered pathway. Proc Natl Acad Sci U S A (2016) 0.77
Meandering Down the Energy Landscape of Protein Folding: Are We There Yet? Biophys J (2016) 0.76
Simultaneous Determination of Two Subdomain Folding Rates Using the "Transfer-Quench" Method. Biophys J (2017) 0.75
Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry. Proc Natl Acad Sci U S A (2017) 0.75
Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data. Front Mol Biosci (2017) 0.75
High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC. PLoS Pathog (2016) 0.75
Computational method allowing Hydrogen-Deuterium Exchange Mass Spectrometry at single amide Resolution. Sci Rep (2017) 0.75
The case for defined protein folding pathways. Proc Natl Acad Sci U S A (2017) 0.75
Primary structure effects on peptide group hydrogen exchange. Proteins (1993) 10.79
Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation. Protein Sci (1993) 5.85
Isotope effects in peptide group hydrogen exchange. Proteins (1993) 3.21
Protein analysis by hydrogen exchange mass spectrometry. Annu Rev Biophys Biomol Struct (2003) 2.94
Hydrogen exchange and mass spectrometry: A historical perspective. J Am Soc Mass Spectrom (2006) 2.78
Hydrogen exchange mass spectrometry for studying protein structure and dynamics. Chem Soc Rev (2010) 2.65
Mechanisms and uses of hydrogen exchange. Curr Opin Struct Biol (1996) 2.48
HD desktop: an integrated platform for the analysis and visualization of H/D exchange data. J Am Soc Mass Spectrom (2008) 1.82
Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation. J Am Chem Soc (2005) 1.77
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry. Anal Chem (2009) 1.65
Hydrogen/deuterium exchange-mass spectrometry: a powerful tool for probing protein structure, dynamics and interactions. Curr Med Chem (2007) 1.47
Electron transfer dissociation facilitates the measurement of deuterium incorporation into selectively labeled peptides with single residue resolution. J Am Chem Soc (2008) 1.47
Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions. Expert Rev Proteomics (2011) 1.45
ExMS: data analysis for HX-MS experiments. J Am Soc Mass Spectrom (2011) 1.44
Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein. J Am Chem Soc (2009) 1.35
Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling. J Am Soc Mass Spectrom (2009) 1.33
Electron capture dissociation of electrosprayed protein ions for spatially resolved hydrogen exchange measurements. J Am Chem Soc (2008) 1.25
Hydrogen exchange mass spectrometry: are we out of the quicksand? J Am Soc Mass Spectrom (2012) 1.23
Protein dynamics viewed by hydrogen exchange. Protein Sci (2012) 1.22
Many overlapping peptides for protein hydrogen exchange experiments by the fragment separation-mass spectrometry method. J Am Soc Mass Spectrom (2011) 1.22
Protein hydrogen exchange: testing current models. Protein Sci (2012) 1.20
The foldon substructure of staphylococcal nuclease. J Mol Biol (2007) 1.09
Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization. Biochemistry (2011) 1.09
Minimizing back exchange in the hydrogen exchange-mass spectrometry experiment. J Am Soc Mass Spectrom (2012) 1.05
Automated hydrogen/deuterium exchange electron transfer dissociation high resolution mass spectrometry measured at single-amide resolution. J Am Soc Mass Spectrom (2011) 1.01
Improved protein hydrogen/deuterium exchange mass spectrometry platform with fully automated data processing. Anal Chem (2012) 1.00
Characterizing short-lived protein folding intermediates by top-down hydrogen exchange mass spectrometry. Anal Chem (2010) 0.98
Mass spectrometry-based methods to study protein architecture and dynamics. Protein Sci (2013) 0.97
Conformer-specific hydrogen exchange analysis of Aβ(1-42) oligomers by top-down electron capture dissociation mass spectrometry. Anal Chem (2011) 0.97
Spatially resolved protein hydrogen exchange measured by matrix-assisted laser desorption ionization in-source decay. Anal Chem (2011) 0.89
Fragmentation hydrogen exchange mass spectrometry: a review of methodology and applications. Protein Expr Purif (2012) 0.89
Structure and dynamics of small soluble Aβ(1-40) oligomers studied by top-down hydrogen exchange mass spectrometry. Biochemistry (2012) 0.89
Computing H/D-exchange rates of single residues from data of proteolytic fragments. BMC Bioinformatics (2010) 0.87
Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry. J Am Soc Mass Spectrom (2008) 0.86
A simple test to detect hydrogen/deuterium scrambling during gas-phase peptide fragmentation. Anal Chem (2008) 0.85
Unraveling the dynamics of protein interactions with quantitative mass spectrometry. Crit Rev Biochem Mol Biol (2011) 0.85
Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dissociation. Anal Chem (2012) 0.85
New developments in protein structure-function analysis by MS and use of hydrogen-deuterium exchange microfluidics. FEBS J (2011) 0.82
Improved sequence resolution by global analysis of overlapped peptides in hydrogen/deuterium exchange mass spectrometry. J Am Soc Mass Spectrom (2012) 0.80
Structural interrogation of electrosprayed peptide ions by gas-phase H/D exchange and electron capture dissociation mass spectrometry. Anal Chem (2011) 0.80
Hydrogen-deuterium exchange coupled to mass spectrometry to investigate ligand-receptor interactions. Methods Mol Biol (2012) 0.78
Hydrogen exchange methods to study protein folding. Methods (2004) 2.47
Protein folding: the stepwise assembly of foldon units. Proc Natl Acad Sci U S A (2005) 2.29
Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry. Proc Natl Acad Sci U S A (2003) 2.09
The E46K mutation in alpha-synuclein increases amyloid fibril formation. J Biol Chem (2005) 1.98
Urea, but not guanidinium, destabilizes proteins by forming hydrogen bonds to the peptide group. Proc Natl Acad Sci U S A (2009) 1.73
Fast and slow intermediate accumulation and the initial barrier mechanism in protein folding. J Mol Biol (2002) 1.70
Protein folding and misfolding: mechanism and principles. Q Rev Biophys (2008) 1.68
Structure and properties of alpha-synuclein and other amyloids determined at the amino acid level. Proc Natl Acad Sci U S A (2005) 1.65
Protein hydrogen exchange mechanism: local fluctuations. Protein Sci (2003) 1.63
How cytochrome c folds, and why: submolecular foldon units and their stepwise sequential stabilization. J Mol Biol (2004) 1.51
Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry. Proc Natl Acad Sci U S A (2009) 1.50
ExMS: data analysis for HX-MS experiments. J Am Soc Mass Spectrom (2011) 1.44
Cytochrome c folding pathway: kinetic native-state hydrogen exchange. Proc Natl Acad Sci U S A (2002) 1.37
Order of steps in the cytochrome C folding pathway: evidence for a sequential stabilization mechanism. J Mol Biol (2006) 1.36
Cooperative omega loops in cytochrome c: role in folding and function. J Mol Biol (2003) 1.35
Stepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometry. Proc Natl Acad Sci U S A (2013) 1.34
Replacement of histone H3 with CENP-A directs global nucleosome array condensation and loosening of nucleosome superhelical termini. Proc Natl Acad Sci U S A (2011) 1.33
The N-terminal to C-terminal motif in protein folding and function. Proc Natl Acad Sci U S A (2005) 1.29
Recombinant equine cytochrome c in Escherichia coli: high-level expression, characterization, and folding and assembly mutants. Biochemistry (2002) 1.29
Protein dynamics viewed by hydrogen exchange. Protein Sci (2012) 1.22
Many overlapping peptides for protein hydrogen exchange experiments by the fragment separation-mass spectrometry method. J Am Soc Mass Spectrom (2011) 1.22
Protein hydrogen exchange: testing current models. Protein Sci (2012) 1.20
Folding trajectories of human dihydrofolate reductase inside the GroEL GroES chaperonin cavity and free in solution. Proc Natl Acad Sci U S A (2007) 1.12
Intimate view of a kinetic protein folding intermediate: residue-resolved structure, interactions, stability, folding and unfolding rates, homogeneity. J Mol Biol (2003) 1.11
Folding units govern the cytochrome c alkaline transition. J Mol Biol (2003) 1.11
A unified mechanism for protein folding: predetermined pathways with optional errors. Protein Sci (2007) 1.09
The foldon substructure of staphylococcal nuclease. J Mol Biol (2007) 1.09
Minimizing back exchange in the hydrogen exchange-mass spectrometry experiment. J Am Soc Mass Spectrom (2012) 1.05
Submolecular cooperativity produces multi-state protein unfolding and refolding. Biophys Chem (2002) 1.04
An efficient organic solvent based extraction method for the proteomic analysis of Arabidopsis plasma membranes. J Proteome Res (2009) 1.04
Folding of a large protein at high structural resolution. Proc Natl Acad Sci U S A (2013) 1.02
Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry. Proc Natl Acad Sci U S A (2012) 1.00
Functional role of a protein foldon--an Omega-loop foldon controls the alkaline transition in ferricytochrome c. Proteins (2006) 0.99
The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching. J Cell Biol (2008) 0.97
Protein misfolding: optional barriers, misfolded intermediates, and pathway heterogeneity. J Mol Biol (2004) 0.95
Protein folding: independent unrelated pathways or predetermined pathway with optional errors. Proc Natl Acad Sci U S A (2008) 0.94
Branching in the sequential folding pathway of cytochrome c. Protein Sci (2007) 0.93
Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry. Biochemistry (2012) 0.90
Backbone and side-chain heteronuclear resonance assignments and hyperfine NMR shifts in horse cytochrome c. Protein Sci (2003) 0.89
AMORE-HX: a multidimensional optimization of radial enhanced NMR-sampled hydrogen exchange. J Biomol NMR (2009) 0.88
Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry. J Lipid Res (2013) 0.85
Fast structural dynamics in reduced and oxidized cytochrome c. Protein Sci (2009) 0.83
Berger C. Mayne (1920-2011): a friend and his contributions to photosynthesis research. Photosynth Res (2012) 0.75