Published in PLoS One on March 15, 2013
EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells. Cell Cycle (2013) 0.83
Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation. FEBS J (2014) 0.81
Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts. PLoS One (2014) 0.77
Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src. Oncotarget (2016) 0.77
GW5074 and PP2 kinase inhibitors implicate nontraditional c-Raf and Lyn function as drivers of retinoic acid-induced maturation. Cell Signal (2015) 0.75
Induced myelomonocytic differentiation in leukemia cells is accompanied by noncanonical transcription factor expression. FEBS Open Bio (2015) 0.75
The selectivity of protein kinase inhibitors: a further update. Biochem J (2007) 15.73
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem (1996) 10.08
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta (2006) 7.33
Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat Rev Mol Cell Biol (2005) 7.07
Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci U S A (1980) 6.65
Regulation of Raf-1 by direct feedback phosphorylation. Mol Cell (2005) 5.88
The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression. Blood (1987) 3.90
Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide. J Exp Med (1979) 2.80
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia. FASEB J (1991) 2.75
Identification of the major phosphorylation sites of the Raf-1 kinase. J Biol Chem (1993) 2.70
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism. Proc Natl Acad Sci U S A (2001) 2.58
Retinoids, retinoic acid receptors, and cancer. Annu Rev Pathol (2011) 2.40
MEK kinase activity is not necessary for Raf-1 function. EMBO J (2001) 2.36
The HL60 cell line: a model system for studying human myeloid cell differentiation. Br J Cancer Suppl (1988) 1.58
Retinoid pathway and cancer therapeutics. Adv Drug Deliv Rev (2010) 1.53
Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest. Cancer Res (1998) 1.52
A critical role for Lyn in acute myeloid leukemia. Blood (2007) 1.40
A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell. Mol Cell Biol (1990) 1.37
Leukocyte CD11/CD18 integrins: biological and clinical relevance. Haematologica (1995) 1.37
Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition. J Biol Chem (2003) 1.28
Dephosphorylation of Ser-259 regulates Raf-1 membrane association. J Biol Chem (2001) 1.25
Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase. Mol Biol Cell (2006) 1.24
Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity. Blood (1992) 1.16
A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation. Blood (1997) 1.16
A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. J Biol Chem (2007) 1.16
Phosphatase and feedback regulation of Raf-1 signaling. Cell Cycle (2007) 1.15
Therapeutic targeting of Src-kinase Lyn in myeloid leukemic cell growth. Leukemia (1999) 1.11
Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis. J Clin Invest (2002) 1.09
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol Cell (2008) 1.08
Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn. Exp Cell Res (2010) 1.06
Inhibition of Src family kinases enhances retinoic acid induced gene expression and myeloid differentiation. Mol Cancer Ther (2007) 1.05
Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells. Leukemia (2011) 1.05
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. J Cell Biochem (2006) 1.02
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res (2008) 1.02
Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta. Cancer Chemother Pharmacol (2005) 1.01
Control of HL-60 cell differentiation lineage specificity, a late event occurring after precommitment. Cancer Res (1987) 1.01
Evaluation of the process for superoxide production by NADPH oxidase in human neutrophils: evidence for cytoplasmic origin of superoxide. Redox Rep (2001) 0.97
Dasatinib promotes ATRA-induced differentiation of AML cells. Leukemia (2009) 0.97
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. Exp Cell Res (2009) 0.96
Expression of src family genes during monocytic differentiation of HL-60 cells. J Immunol (1991) 0.94
Identification of a population of bipotent stem cells in the HL60 human promyelocytic leukemia cell line. Proc Natl Acad Sci U S A (1981) 0.93
Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation. Exp Cell Res (2009) 0.91
Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells. FASEB J (2008) 0.88
Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells. Eur J Cell Biol (2005) 0.88
Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2. J Biol Chem (2004) 0.88
c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. J Biol Chem (2009) 0.87
Involvement of retinoic acid receptor-alpha-mediated signaling pathway in induction of CD38 cell-surface antigen. Blood (1997) 0.87
Location and functional significance of retinol-binding sites on the serine/threonine kinase, c-Raf. J Biol Chem (2004) 0.86
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation. Biochem Biophys Res Commun (2006) 0.85
Vav promotes differentiation of human tumoral myeloid precursors. Exp Cell Res (2005) 0.85
Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2. Biochem Biophys Res Commun (2006) 0.84
Association of PI 3-K with tyrosine phosphorylated Vav is essential for its activity in neutrophil-like maturation of myeloid cells. Cell Signal (2004) 0.80
Mutation in the ligand-binding domain of the retinoic acid receptor alpha in HL-60 leukemic cells resistant to retinoic acid and with increased sensitivity to vitamin D3 analogs. Leuk Res (1996) 0.78
c-kit expression identifies cardiovascular precursors in the neonatal heart. Proc Natl Acad Sci U S A (2009) 2.06
A review of the mammalian unfolded protein response. Biotechnol Bioeng (2011) 1.83
Engineering the spatial organization of metabolic enzymes: mimicking nature's synergy. Curr Opin Biotechnol (2008) 1.76
Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies. PLoS Comput Biol (2007) 1.33
Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. Environ Sci Technol (2014) 1.25
A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. J Biol Chem (2007) 1.16
Activation of the aryl hydrocarbon receptor AhR Promotes retinoic acid-induced differentiation of myeloblastic leukemia cells by restricting expression of the stem cell transcription factor Oct4. Cancer Res (2011) 1.07
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. J Cell Biochem (2006) 1.02
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res (2008) 1.02
Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells. Cancer Res (2007) 0.99
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. Exp Cell Res (2009) 0.96
Physicochemical regulation of endothelial sprouting in a 3D microfluidic angiogenesis model. J Biomed Mater Res A (2013) 0.95
Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems. PLoS One (2010) 0.94
Hydrodynamic optical alignment for microflow cytometry. Lab Chip (2011) 0.94
Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells. Leuk Lymphoma (2011) 0.92
Multiscale models of breast cancer progression. Ann Biomed Eng (2012) 0.91
Mechanism-based small molecule probes for labeling CD38 on live cells. J Am Chem Soc (2009) 0.90
A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression. Mol Cell Biol (2004) 0.90
Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Res (2006) 0.89
CT screening and follow-up of lung nodules: effects of tube current-time setting and nodule size and density on detectability and of tube current-time setting on apparent size. AJR Am J Roentgenol (2011) 0.89
c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. J Biol Chem (2009) 0.87
ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary. Exp Cell Res (2010) 0.87
All-trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL-60 leukemia cells. Am J Hematol (2006) 0.86
Ensembles of signal transduction models using Pareto Optimal Ensemble Techniques (POETs). Biotechnol J (2010) 0.86
Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells. Integr Biol (Camb) (2011) 0.85
Inhibiting the platelet derived growth factor receptor increases signs of retinoic acid syndrome in myeloid differentiated HL-60 cells. FEBS Lett (2008) 0.85
A test of highly optimized tolerance reveals fragile cell-cycle mechanisms are molecular targets in clinical cancer trials. PLoS One (2008) 0.85
Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation. Exp Cell Res (2008) 0.84
Magnetic endoscope imaging (ScopeGuide) elucidates the mechanism of action of the pain-alleviating impact of water exchange colonoscopy - attenuation of loop formation. J Interv Gastroenterol (2012) 0.84
6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Mol Cancer (2013) 0.83
Retinoic acid-induced growth arrest and differentiation: retinoic acid up-regulates CD32 (Fc gammaRII) expression, the ectopic expression of which retards the cell cycle. Mol Cancer Ther (2002) 0.83
Ensembles of uncertain mathematical models can identify network response to therapeutic interventions. Mol Biosyst (2010) 0.82
Venous hypertension and cerebral aneurysm rupture. Neuroradiol J (2011) 0.81
The proliferation inhibitory proteins p27(Kip1) and retinoblastoma are involved in the control of equine lymphocyte proliferation. Vet Immunol Immunopathol (2004) 0.81
Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation. FEBS J (2014) 0.81
Stochastic reaction-diffusion simulation of enzyme compartmentalization reveals improved catalytic efficiency for a synthetic metabolic pathway. Metab Eng (2007) 0.80
Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. J Am Chem Soc (2014) 0.80
Cybernetic model predictive control of a continuous bioreactor with cell recycle. Biotechnol Prog (2003) 0.80
Computational modeling and analysis of insulin induced eukaryotic translation initiation. PLoS Comput Biol (2011) 0.80
Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. Oncology (2009) 0.79
Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. Leuk Lymphoma (2010) 0.79
Ubiquibodies, synthetic E3 ubiquitin ligases endowed with unnatural substrate specificity for targeted protein silencing. J Biol Chem (2014) 0.79
Recurrent pneumonia, persistent cough, and dyspnea in a 41-year-old man. Chest (2012) 0.79
RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition. Cell Cycle (2010) 0.79
Ectopic expression of CXCR5/BLR1 accelerates retinoic acid- and vitamin D(3)-induced monocytic differentiation of U937 cells. Exp Biol Med (Maywood) (2002) 0.78
Anti-factor IXa Aptamer reduces propagation of thrombin generation in plasma anticoagulated with warfarin. Thromb Res (2009) 0.76
Hierarchical approaches for systems modeling in cardiac development. Wiley Interdiscip Rev Syst Biol Med (2013) 0.75
Augmenting Interpretation of Chest Radiographs With Deep Learning Probability Maps. J Thorac Imaging (2020) 0.75
Impact of water exchange colonoscopy on serum sodium and potassium levels: an observational study. Dig Dis Sci (2013) 0.75
Retinoic acid therapy served by ligands cross linking and masking CD38. Leuk Res (2006) 0.75