Published in PLoS Genet on April 04, 2013
A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole. PLoS Biol (2014) 1.69
Current and emerging Legionella diagnostics for laboratory and outbreak investigations. Clin Microbiol Rev (2015) 1.41
Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis. BMC Infect Dis (2014) 1.25
Recent insights into Candida albicans biofilm resistance mechanisms. Curr Genet (2013) 1.20
The fitness consequences of aneuploidy are driven by condition-dependent gene effects. PLoS Biol (2015) 0.93
The Candida pathogenic species complex. Cold Spring Harb Perspect Med (2014) 0.86
NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning. PLoS Comput Biol (2016) 0.85
Synergy Maps: exploring compound combinations using network-based visualization. J Cheminform (2015) 0.82
Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive. Mol Cell Biol (2016) 0.80
Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence. PLoS Pathog (2015) 0.80
Disruption of the transcriptional regulator Cas5 results in enhanced killing of Candida albicans by Fluconazole. Antimicrob Agents Chemother (2014) 0.79
Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress. PLoS Genet (2016) 0.78
Dual action antifungal small molecule modulates multidrug efflux and TOR signaling. Nat Chem Biol (2016) 0.77
Ploidy-regulated variation in biofilm-related phenotypes in natural isolates of Saccharomyces cerevisiae. G3 (Bethesda) (2014) 0.77
Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks Candida albicans Morphogenesis, and Is Effluxed via Yor1 and Circuitry Controlled by Zcf29. Antimicrob Agents Chemother (2016) 0.76
Molecular Characterization of Gβ-Like Protein CpcB Involved in Antifungal Drug Susceptibility and Virulence in A. fumigatus. Front Microbiol (2016) 0.76
Bioactivity in Rhododendron: A Systemic Analysis of Antimicrobial and Cytotoxic Activities and Their Phylogenetic and Phytochemical Origins. Front Plant Sci (2017) 0.75
Encyclopedia of bacterial gene circuits whose presence or absence correlate with pathogenicity--a large-scale system analysis of decoded bacterial genomes. BMC Genomics (2015) 0.75
Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome. MBio (2016) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
The Sequence Alignment/Map format and SAMtools. Bioinformatics (2009) 232.39
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res (2008) 157.44
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res (2010) 97.51
Fast gapped-read alignment with Bowtie 2. Nat Methods (2012) 83.79
SOAP: short oligonucleotide alignment program. Bioinformatics (2008) 68.13
A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet (2011) 59.36
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med (1998) 53.26
A survey of sequence alignment algorithms for next-generation sequencing. Brief Bioinform (2010) 18.05
Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev (2007) 15.66
HSP90 and the chaperoning of cancer. Nat Rev Cancer (2005) 11.98
Population genomics of domestic and wild yeasts. Nature (2009) 11.79
Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev (1998) 9.76
HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol (2010) 7.16
Targeting the dynamic HSP90 complex in cancer. Nat Rev Cancer (2010) 6.81
Improved survival among HIV-infected individuals following initiation of antiretroviral therapy. JAMA (1998) 6.69
Savant: genome browser for high-throughput sequencing data. Bioinformatics (2010) 6.51
The diploid genome sequence of Candida albicans. Proc Natl Acad Sci U S A (2004) 6.34
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins. Cell (2009) 6.20
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell (1997) 5.73
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus. Antimicrob Agents Chemother (1997) 5.66
hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. Mol Cell Biol (1989) 5.37
CNV-seq, a new method to detect copy number variation using high-throughput sequencing. BMC Bioinformatics (2009) 5.14
Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi. Science (2005) 5.04
Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry. Clin Infect Dis (2009) 4.59
Humans as the world's greatest evolutionary force. Science (2001) 4.51
Aneuploidy and isochromosome formation in drug-resistant Candida albicans. Science (2006) 4.09
Epidemiology of invasive mycoses in North America. Crit Rev Microbiol (2010) 4.06
Hsp90 molecular chaperone inhibitors: are we there yet? Clin Cancer Res (2012) 4.01
Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment. Am J Med (2012) 4.00
Tackling antibiotic resistance. Nat Rev Microbiol (2011) 3.95
Candida Albicans: a molecular revolution built on lessons from budding yeast. Nat Rev Genet (2002) 3.46
Saccharomyces Genome Database provides mutant phenotype data. Nucleic Acids Res (2009) 3.38
Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature (1995) 3.36
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data. Bioinformatics (2012) 3.21
Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence. Mol Microbiol (2003) 3.12
Projected life expectancy of people with HIV according to timing of diagnosis. AIDS (2012) 3.09
Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase. Proc Natl Acad Sci U S A (1991) 3.02
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 2.97
PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J Biol Chem (1994) 2.92
Calcineurin is essential for survival during membrane stress in Candida albicans. EMBO J (2002) 2.81
Antibiotic interactions that select against resistance. Nature (2007) 2.70
Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat Rev Microbiol (2007) 2.60
Evolution of drug resistance in experimental populations of Candida albicans. J Bacteriol (2000) 2.58
Tackling human fungal infections. Science (2012) 2.49
Evolution of antifungal-drug resistance: mechanisms and pathogen fitness. Nat Rev Microbiol (2005) 2.47
Accelerated evolution of resistance in multidrug environments. Proc Natl Acad Sci U S A (2008) 2.45
Drug interactions and the evolution of antibiotic resistance. Nat Rev Microbiol (2009) 2.40
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease. Proc Natl Acad Sci U S A (2009) 2.35
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1. Mol Microbiol (2008) 2.34
Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans. Antimicrob Agents Chemother (2000) 2.27
Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin. Cell Stress Chaperones (1998) 2.25
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples. Nucleic Acids Res (2010) 2.20
Population biological principles of drug-resistance evolution in infectious diseases. Lancet Infect Dis (2011) 2.11
Genetic architecture of Hsp90-dependent drug resistance. Eukaryot Cell (2006) 2.09
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. PLoS Genet (2009) 2.07
The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nat Rev Microbiol (2008) 2.06
The probability that beneficial mutations are lost in populations with periodic bottlenecks. Evolution (2001) 2.05
Drug interactions modulate the potential for evolution of resistance. Proc Natl Acad Sci U S A (2008) 1.98
Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms. BMC Genomics (2006) 1.91
Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol Mol Biol Rev (2011) 1.90
Calcineurin. Structure, function, and inhibition. Cell Biochem Biophys (1999) 1.82
Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei. Antimicrob Agents Chemother (2003) 1.80
Sphingolipid functions in Saccharomyces cerevisiae. Biochim Biophys Acta (2002) 1.79
Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol (2007) 1.79
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS Pathog (2009) 1.76
Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance. Eukaryot Cell (2008) 1.73
Fungal infections in solid-organ transplantation. Clin Infect Dis (1993) 1.67
Resistance of human fungal pathogens to antifungal drugs. Curr Opin Microbiol (2002) 1.65
Divergence in fitness and evolution of drug resistance in experimental populations of Candida albicans. J Bacteriol (2001) 1.63
PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. PLoS Pathog (2010) 1.63
Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms. Antimicrob Agents Chemother (2008) 1.62
Hypermutation as a factor contributing to the acquisition of antimicrobial resistance. Clin Infect Dis (2003) 1.58
Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics (2003) 1.57
The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. Mol Cell Biol (1994) 1.54
Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids. J Bacteriol (1991) 1.53
Multiple amino acid substitutions in lanosterol 14alpha-demethylase contribute to azole resistance in Candida albicans. Microbiology (1999) 1.53
Hsp90 governs dispersion and drug resistance of fungal biofilms. PLoS Pathog (2011) 1.53
New tools at the Candida Genome Database: biochemical pathways and full-text literature search. Nucleic Acids Res (2009) 1.51
Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol (2011) 1.51
Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. EMBO J (1995) 1.47
Genomic plasticity of the human fungal pathogen Candida albicans. Eukaryot Cell (2010) 1.46
Evolutionary insight from whole-genome sequencing of experimentally evolved microbes. Mol Ecol (2012) 1.45
Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin. Mol Cell Biol (2000) 1.40
Heat shock protein 90 in neurodegenerative diseases. Mol Neurodegener (2010) 1.38
Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae. EMBO J (2002) 1.29
Optimal drug synergy in antimicrobial treatments. PLoS Comput Biol (2010) 1.23
Regulation of pleiotropic drug resistance in yeast. Drug Resist Updat (1999) 1.17
Determinants of divergent adaptation and Dobzhansky-Muller interaction in experimental yeast populations. Curr Biol (2010) 1.15
Cyclophilin residues that affect noncompetitive inhibition of the protein serine phosphatase activity of calcineurin by the cyclophilin.cyclosporin A complex. Biochemistry (1994) 1.14
Structural basis of the radicicol resistance displayed by a fungal hsp90. ACS Chem Biol (2009) 1.10
The 2012 Garrod lecture: discovery of antibacterial drugs in the 21st century. J Antimicrob Chemother (2012) 1.04
The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans. Mol Microbiol (2012) 1.01
The identification of myriocin-binding proteins. Chem Biol (1999) 1.00
Antagonism between two mechanisms of antifungal drug resistance. Eukaryot Cell (2006) 0.89
Exploring gene function and drug action using chemogenomic dosage assays. Methods Enzymol (2010) 0.89
The chemical biology of immunophilin ligands. Curr Med Chem (2011) 0.89
A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta. Biochem Pharmacol (2010) 0.88
Fungal infections in oncology patients: update on epidemiology, prevention, and treatment. Curr Opin Oncol (2010) 0.87
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The genetic landscape of a cell. Science (2010) 16.52
A high-resolution atlas of nucleosome occupancy in yeast. Nat Genet (2007) 12.21
An "Electronic Fluorescent Pictograph" browser for exploring and analyzing large-scale biological data sets. PLoS One (2007) 9.60
The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science (2008) 8.52
Most "dark matter" transcripts are associated with known genes. PLoS Biol (2010) 6.60
Quantitative phenotyping via deep barcode sequencing. Genome Res (2009) 5.13
Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. Proc Natl Acad Sci U S A (2004) 5.10
Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics (2005) 5.08
Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nat Genet (2007) 4.59
A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell (2008) 4.49
Genotype to phenotype: a complex problem. Science (2010) 2.92
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia. Cancer Cell (2011) 2.68
Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling. Curr Biol (2009) 2.50
A predicted interactome for Arabidopsis. Plant Physiol (2007) 2.41
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol (2012) 2.40
Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures. Nat Protoc (2007) 2.36
Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PLoS Genet (2005) 2.32
Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nat Biotechnol (2011) 2.26
An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol (2008) 2.21
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples. Nucleic Acids Res (2010) 2.20
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. PLoS Genet (2009) 2.07
Combination chemical genetics. Nat Chem Biol (2008) 1.98
A unique and universal molecular barcode array. Nat Methods (2006) 1.96
Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol Mol Biol Rev (2011) 1.90
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet (2009) 1.90
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome. Nucleic Acids Res (2005) 1.89
Systematic exploration of synergistic drug pairs. Mol Syst Biol (2011) 1.89
Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Nat Biotechnol (2011) 1.77
Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLoS Pathog (2009) 1.76
Global gene deletion analysis exploring yeast filamentous growth. Science (2012) 1.67
Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise. Curr Biol (2012) 1.65
Compound prioritization methods increase rates of chemical probe discovery in model organisms. Chem Biol (2011) 1.64
PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. PLoS Pathog (2010) 1.63
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation. PLoS Genet (2010) 1.59
Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics (2003) 1.57
Chromatin is an ancient innovation conserved between Archaea and Eukarya. Elife (2012) 1.56
Yeast Barcoders: a chemogenomic application of a universal donor-strain collection carrying bar-code identifiers. Nat Methods (2008) 1.56
Diversity of eukaryotic DNA replication origins revealed by genome-wide analysis of chromatin structure. PLoS Genet (2010) 1.54
Hsp90 governs dispersion and drug resistance of fungal biofilms. PLoS Pathog (2011) 1.53
Extensive role of the general regulatory factors, Abf1 and Rap1, in determining genome-wide chromatin structure in budding yeast. Nucleic Acids Res (2010) 1.48
The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Res (2008) 1.44
Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action. Genome Biol (2010) 1.42
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans. Nat Chem Biol (2010) 1.41
The effects of intrathecal morphine on patients undergoing minimally invasive direct coronary artery bypass surgery. J Cardiothorac Vasc Anesth (2005) 1.40
Multiple means to the same end: the genetic basis of acquired stress resistance in yeast. PLoS Genet (2011) 1.40
Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (2014) 1.39
Introns regulate RNA and protein abundance in yeast. Genetics (2006) 1.39
Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast. PLoS Genet (2008) 1.37
Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. J Cell Biol (2010) 1.36
DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology. Chem Biol (2013) 1.29
Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Mol Cell (2009) 1.24
Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen. PLoS Genet (2008) 1.18
A survey of yeast genomic assays for drug and target discovery. Pharmacol Ther (2010) 1.18
Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection. PLoS Pathog (2010) 1.17
Yeast chemical genomics and drug discovery: an update. Trends Pharmacol Sci (2008) 1.17
Identification of genes involved in the toxic response of Saccharomyces cerevisiae against iron and copper overload by parallel analysis of deletion mutants. Toxicol Sci (2007) 1.16
Bugs, drugs and chemical genomics. Nat Chem Biol (2011) 1.15
Alternative splicing of PTC7 in Saccharomyces cerevisiae determines protein localization. Genetics (2009) 1.14
A comprehensive platform for highly multiplexed mammalian functional genetic screens. BMC Genomics (2011) 1.12
Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. PLoS One (2012) 1.12
The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4. EMBO J (2011) 1.11
A universal TagModule collection for parallel genetic analysis of microorganisms. Nucleic Acids Res (2010) 1.11
Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. PLoS Pathog (2012) 1.10
Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay. J Nat Prod (2007) 1.10
Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae. Genome Biol (2012) 1.09
Recent advances and method development for drug target identification. Trends Pharmacol Sci (2009) 1.09
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection. Nat Methods (2011) 1.08
Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry. PLoS Genet (2012) 1.07
Chemical-genetic approaches for exploring the mode of action of natural products. Prog Drug Res (2008) 1.04
A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription. PLoS Genet (2013) 1.04
Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest (2012) 1.04
Whole genome duplication and enrichment of metal cation transporters revealed by de novo genome sequencing of extremely halotolerant black yeast Hortaea werneckii. PLoS One (2013) 1.04
The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proc Natl Acad Sci U S A (2008) 1.04
Thermal control of microbial development and virulence: molecular mechanisms of microbial temperature sensing. MBio (2012) 1.03
Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) (2012) 1.02
Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns. Mol Cell Biol (2011) 1.01
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. Nucleic Acids Res (2013) 1.00
Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. J Cell Biol (2013) 0.98
Competitive genomic screens of barcoded yeast libraries. J Vis Exp (2011) 0.97
Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs. Nat Rev Microbiol (2012) 0.96
Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. PLoS Pathog (2012) 0.95
Genome sequence of Shigella flexneri serotype 5a strain M90T Sm. J Bacteriol (2012) 0.95
Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet (2008) 0.94
Experimental approaches to identify genetic networks. Curr Opin Biotechnol (2006) 0.92
Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents. ACS Chem Biol (2012) 0.92
Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection. Genome Biol (2014) 0.91
Elucidating drug resistance in human fungal pathogens. Future Microbiol (2014) 0.90
Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell (2011) 0.90
Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans. Mol Biol Cell (2011) 0.90
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. Cell Rep (2012) 0.90
Exploring gene function and drug action using chemogenomic dosage assays. Methods Enzymol (2010) 0.89
The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. PLoS One (2012) 0.89
Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system. Genome Res (2007) 0.89
Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae. BMC Genomics (2009) 0.88
Precise gene-dose alleles for chemical genetics. Genetics (2009) 0.86