Wah Chiu

Author PubWeight™ 193.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Outcome of the first electron microscopy validation task force meeting. Structure 2012 4.35
2 Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature 2006 3.73
3 Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med 2012 3.54
4 Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy. Nature 2008 3.54
5 De novo backbone trace of GroEL from single particle electron cryomicroscopy. Structure 2008 3.41
6 EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Res 2010 3.32
7 Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol 2006 3.14
8 Protein structure fitting and refinement guided by cryo-EM density. Structure 2008 3.12
9 Refinement of protein structures into low-resolution density maps using rosetta. J Mol Biol 2009 2.94
10 The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell 2003 2.89
11 Mechanism of folding chamber closure in a group II chaperonin. Nature 2010 2.85
12 Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nat Struct Biol 2003 2.76
13 Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat Mater 2011 2.71
14 Common ancestry of herpesviruses and tailed DNA bacteriophages. J Virol 2005 2.60
15 Identification of secondary structure elements in intermediate-resolution density maps. Structure 2007 2.60
16 Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells. J Am Chem Soc 2008 2.56
17 Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy. Structure 2004 2.50
18 Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions. J Struct Biol 2010 2.48
19 The pore structure of the closed RyR1 channel. Structure 2005 2.42
20 Outcome of a workshop on archiving structural models of biological macromolecules. Structure 2006 2.32
21 Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure 2004 2.30
22 Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure 2006 2.26
23 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc Natl Acad Sci U S A 2010 2.17
24 Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus. Nat Struct Mol Biol 2010 2.12
25 Refinement of protein structures by iterative comparative modeling and CryoEM density fitting. J Mol Biol 2006 2.06
26 An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate. Structure 2006 2.04
27 Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proc Natl Acad Sci U S A 2011 2.03
28 Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency. J Struct Biol 2012 1.94
29 Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography. J Mol Biol 2006 1.90
30 Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm. J Struct Biol 2007 1.90
31 The molecular architecture of the eukaryotic chaperonin TRiC/CCT. Structure 2012 1.80
32 DNA packaging and delivery machines in tailed bacteriophages. Curr Opin Struct Biol 2007 1.79
33 A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol 2005 1.78
34 4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. EMBO J 2011 1.77
35 Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure. Structure 2011 1.71
36 Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. J Mol Biol 2010 1.71
37 A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol 2004 1.70
38 Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A 2008 1.68
39 Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins. Nat Struct Mol Biol 2007 1.67
40 Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy. J Struct Biol 2005 1.67
41 Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol Cell 2005 1.65
42 JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles. J Struct Biol 2008 1.62
43 Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV. J Struct Biol 2006 1.61
44 Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions. Structure 2010 1.60
45 Structure of the acrosomal bundle. Nature 2004 1.59
46 Cryo-EM of macromolecular assemblies at near-atomic resolution. Nat Protoc 2010 1.58
47 3D volume reconstruction of a mouse brain from histological sections using warp filtering. J Neurosci Methods 2006 1.51
48 Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol 2008 1.51
49 Applications of a bilateral denoising filter in biological electron microscopy. J Struct Biol 2003 1.50
50 Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem 2004 1.47
51 Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM. Proc Natl Acad Sci U S A 2009 1.45
52 Electron cryotomography reveals the portal in the herpesvirus capsid. J Virol 2006 1.40
53 Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell 2012 1.40
54 Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. J Mol Biol 2007 1.37
55 Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. J Biol Chem 2003 1.35
56 Automated segmentation of molecular subunits in electron cryomicroscopy density maps. J Struct Biol 2006 1.34
57 Structure of the herpesvirus major capsid protein. EMBO J 2003 1.33
58 Modeling protein structure at near atomic resolutions with Gorgon. J Struct Biol 2011 1.29
59 Model of human low-density lipoprotein and bound receptor based on cryoEM. Proc Natl Acad Sci U S A 2009 1.27
60 Structure of Ca2+ release channel at 14 A resolution. J Mol Biol 2005 1.27
61 Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy. J Biol Chem 2003 1.26
62 Dual action of ATP hydrolysis couples lid closure to substrate release into the group II chaperonin chamber. Cell 2011 1.25
63 Flexible architecture of IP3R1 by Cryo-EM. Structure 2011 1.24
64 Visualizing virus assembly intermediates inside marine cyanobacteria. Nature 2013 1.20
65 Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion. Virology 2004 1.19
66 Learning-based segmentation framework for tissue images containing gene expression data. IEEE Trans Med Imaging 2007 1.17
67 Visualizing GroEL/ES in the act of encapsulating a folding protein. Cell 2013 1.16
68 Determination of icosahedral virus structures by electron cryomicroscopy at subnanometer resolution. Adv Protein Chem 2003 1.16
69 A geometric database for gene expression data. Symp Geom Process 2003 1.15
70 Validation of cryo-EM structure of IP₃R1 channel. Structure 2013 1.15
71 Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection. J Mol Biol 2010 1.15
72 Cryo-EM model validation using independent map reconstructions. Protein Sci 2013 1.13
73 Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. EMBO J 2011 1.12
74 Radiation damage effects at four specimen temperatures from 4 to 100 K. J Struct Biol 2009 1.12
75 Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy. Structure 2009 1.10
76 Object oriented database and electronic notebook for transmission electron microscopy. Microsc Microanal 2003 1.10
77 Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling. Proc Natl Acad Sci U S A 2013 1.10
78 Cryoelectron microscopy of protein IX-modified adenoviruses suggests a new position for the C terminus of protein IX. J Virol 2006 1.09
79 Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. PLoS Comput Biol 2006 1.08
80 Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proc Natl Acad Sci U S A 2001 1.06
81 Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. J Mol Biol 2003 1.05
82 The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A 2002 1.04
83 An examination of the electrostatic interactions between the N-terminal tail of the Brome Mosaic Virus coat protein and encapsidated RNAs. J Mol Biol 2012 1.04
84 Computing a family of skeletons of volumetric models for shape description. Comput Aided Des 2007 1.03
85 Multifunctional RNA nanoparticles. Nano Lett 2014 1.03
86 The 2010 cryo-EM modeling challenge. Biopolymers 2012 1.02
87 TRiC's tricks inhibit huntingtin aggregation. Elife 2013 1.02
88 Automated pipeline for atlas-based annotation of gene expression patterns: application to postnatal day 7 mouse brain. Methods 2009 1.01
89 Reprogramming an ATP-driven protein machine into a light-gated nanocage. Nat Nanotechnol 2013 1.00
90 Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy. Biochemistry 2003 0.98
91 Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope. J Struct Biol 2008 0.98
92 Structure of Trypanosoma brucei flagellum accounts for its bihelical motion. Proc Natl Acad Sci U S A 2011 0.97
93 Near-atomic-resolution cryo-EM for molecular virology. Curr Opin Virol 2011 0.97
94 Fast rotational matching of single-particle images. J Struct Biol 2005 0.96
95 Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther 2002 0.96
96 Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps. Biopolymers 2012 0.96
97 Gorgon and pathwalking: macromolecular modeling tools for subnanometer resolution density maps. Biopolymers 2012 0.96
98 Modular software platform for low-dose electron microscopy and tomography. J Microsc 2007 0.95
99 The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions. J Virol 2011 0.95
100 Cryoelectron microscopy of icosahedral virus particles. Methods Mol Biol 2007 0.94
101 Partially polymerized liposomes: stable against leakage yet capable of instantaneous release for remote controlled drug delivery. Nanotechnology 2011 0.94
102 Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism. Structure 2013 0.94
103 Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography. Adv Exp Med Biol 2012 0.93
104 Crystallographic conformers of actin in a biologically active bundle of filaments. J Mol Biol 2007 0.93
105 Tracing conformational changes in proteins. BMC Struct Biol 2010 0.92
106 Constructing and validating initial Cα models from subnanometer resolution density maps with pathwalking. Structure 2012 0.92
107 A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions. PLoS Pathog 2012 0.91
108 Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. J Biol Chem 2013 0.91
109 MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures. Bioinformatics 2010 0.90
110 The group II chaperonin Mm-Cpn binds and refolds human γD crystallin. Protein Sci 2011 0.90
111 Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopy. J Struct Biol 2011 0.89
112 Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. EMBO J 2004 0.89
113 Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum. J Mol Biol 2002 0.88
114 Structure of isolated nucleocapsids from venezuelan equine encephalitis virus and implications for assembly and disassembly of enveloped virus. J Virol 2003 0.88
115 Focal pair merging for contrast enhancement of single particles. J Struct Biol 2003 0.87
116 Location and flexibility of the unique C-terminal tail of Aquifex aeolicus co-chaperonin protein 10 as derived by cryo-electron microscopy and biophysical techniques. J Mol Biol 2008 0.86
117 Identifying Components in 3D Density Maps of Protein Nanomachines by Multi-scale Segmentation. IEEE NIH Life Sci Syst Appl Workshop 2009 0.86
118 Single-particle electron cryomicroscopy of the ion channels in the excitation-contraction coupling junction. Methods Cell Biol 2007 0.85
119 EMEN2: an object oriented database and electronic lab notebook. Microsc Microanal 2013 0.82
120 Studying large viruses. Adv Protein Chem 2003 0.82
121 Filamentous, mixed micelles of triblock copolymers enhance tumor localization of indocyanine green in a murine xenograft model. Mol Pharm 2011 0.82
122 Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation. Biophys J 2012 0.82
123 Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy. J Am Chem Soc 2010 0.82
124 Workshop on the validation and modeling of electron cryo-microscopy structures of biological nanomachines. Pac Symp Biocomput 2011 0.81
125 Web-based Simulation for Contrast Transfer Function and Envelope Functions. Microsc Microanal 2001 0.81
126 Automated specimen search in cryo-TEM observation with DIFF-defocus imaging. J Electron Microsc (Tokyo) 2010 0.79
127 Exploring new limits in complex biological structures. Curr Opin Struct Biol 2013 0.78
128 Hybrid segmentation framework for tissue images containing gene expression data. Med Image Comput Comput Assist Interv 2005 0.78
129 A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB. Appl Biosaf 2010 0.78
130 Erratum: Structural diversity of supercoiled DNA. Nat Commun 2015 0.77
131 Biophysical methods: structure, dynamics and gorgeous images. Curr Opin Struct Biol 2007 0.76
132 Workshop on molecular animation. Structure 2010 0.75
133 Cryo-EM techniques to resolve the structure of HSV-1 capsid-associated components. Methods Mol Biol 2014 0.75
134 Electron beam coater for reduction of charging in ice-embedded biological specimens using Ti(88)Si(12) alloy. Microsc Microanal 2003 0.75
135 Virus structure. Preface. Adv Protein Chem 2003 0.75
136 Decontamination of SARS-CoV-2 and other RNA viruses from N95 level meltblown polypropylene fabric using heat under different humidities. medRxiv 2020 0.75
137 A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. bioRxiv 2020 0.75
138 Corrigendum: Protruding knob-like proteins violate local symmetries in an icosahedral marine virus. Nat Commun 2015 0.75
139 The 4th Annual Meeting of the American Society for Nanomedicine. J Neuroimmune Pharmacol 2014 0.75
140 The pseudo-atomic structure of an RND-type tripartite multidrug efflux pump. Biol Chem 2015 0.75