Published in Nat Rev Cardiol on April 30, 2013
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circ Res (2004) 4.13
Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation (2003) 3.68
Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids. Science (2004) 3.63
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
The roles of senescence and telomere shortening in cardiovascular disease. Nat Rev Cardiol (2013) 1.48
Genetics of leukocyte telomere length and its role in atherosclerosis. Mutat Res (2011) 1.44
Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet (1998) 1.39
Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells. J Cell Physiol (2008) 0.96
Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims. Cytogenet Genome Res (2009) 0.89
Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice. PLoS One (2010) 0.85
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. EMBO J (2004) 2.18
Involvement of mammalian Mus81 in genome integrity and tumor suppression. Science (2004) 2.03
Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol (2007) 1.87
Anti-proliferative activity of silver nanoparticles. BMC Cell Biol (2009) 1.80
Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J (2003) 1.68
Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol (2004) 1.63
A role for Brca1 in chromosome end maintenance. Hum Mol Genet (2006) 1.29
Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability. Curr Biol (2005) 1.24
Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet (2011) 1.23
Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation. Cancer Res (2002) 1.20
Collaboration of Brca1 and Chk2 in tumorigenesis. Genes Dev (2004) 1.18
Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress. Cancer Res (2007) 1.09
Functional interplay of p53 and Mus81 in DNA damage responses and cancer. Cancer Res (2007) 1.03
DNA damage and p53-mediated growth arrest in human cells treated with platinum nanoparticles. Nanomedicine (Lond) (2010) 1.01
TAp73 is a downstream target of p53 in controlling the cellular defense against stress. J Biol Chem (2007) 1.01
Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo. EMBO J (2010) 1.00
Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis. Cancer Res (2002) 1.00
Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells. PLoS One (2010) 0.98
Telomere and telomerase modulation by the mammalian Rad9/Rad1/Hus1 DNA-damage-checkpoint complex. Curr Biol (2006) 0.97
Health impact and safety of engineered nanomaterials. Chem Commun (Camb) (2011) 0.97
Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis. J Cell Sci (2005) 0.97
Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr (2012) 0.96
Short dysfunctional telomeres impair the repair of arsenite-induced oxidative damage in mouse cells. J Cell Physiol (2008) 0.96
Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells. J Cell Biochem (2013) 0.93
Lack of poly(ADP-ribose) polymerase-1 gene product enhances cellular sensitivity to arsenite. Cancer Res (2005) 0.92
Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells. Cancer Prev Res (Phila) (2013) 0.91
Oxidative damage induced genotoxic effects in human fibroblasts from Xeroderma Pigmentosum group A patients. Int J Biochem Cell Biol (2008) 0.91
Isoform-specific activation of protein kinase c in irradiated human fibroblasts and their bystander cells. Int J Biochem Cell Biol (2007) 0.91
Retracted Environmental toxicogenomics: a post-genomic approach to analysing biological responses to environmental toxins. Int J Biochem Cell Biol (2009) 0.91
Telomere-mediated genomic instability and the clinico-pathological parameters in breast cancer. Genes Chromosomes Cancer (2008) 0.90
Annexin-1 protects MCF7 breast cancer cells against heat-induced growth arrest and DNA damage. Cancer Lett (2010) 0.89
A role for Mus81 in the repair of chromium-induced DNA damage. Mutat Res (2008) 0.88
Telomere-mediated chromosomal instability triggers TLR4 induced inflammation and death in mice. PLoS One (2010) 0.85
Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals. Radiat Res (2004) 0.85
Human embryonic stem cells may display higher resistance to genotoxic stress as compared to primary explanted somatic cells. Stem Cells Dev (2008) 0.85
Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics. Mol Cancer Ther (2007) 0.84
Inhibition of poly (ADP-Ribose) polymerase-1 in telomerase deficient mouse embryonic fibroblasts increases arsenite-induced genome instability. Genome Integr (2010) 0.84
Enhanced genotoxicity of silver nanoparticles in DNA repair deficient Mammalian cells. Front Genet (2012) 0.84
Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. Mutat Res (2007) 0.82
Comparison of lymphocyte apoptotic index and qualitative DNA damage in yoga practitioners and breast cancer patients: A pilot study. Int J Yoga (2013) 0.81
Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress. J Cell Mol Med (2009) 0.81
Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells. Genes Chromosomes Cancer (2012) 0.81
The difference in LET and ion species dependence for induction of initially measured and non-rejoined chromatin breaks in normal human fibroblasts. Radiat Res (2008) 0.80
Cationic antimicrobial peptides and biogenic silver nanoparticles kill mycobacteria without eliciting DNA damage and cytotoxicity in mouse macrophages. Antimicrob Agents Chemother (2013) 0.80
Folate deficiency is associated with the formation of complex nuclear anomalies in the cytokinesis-block micronucleus cytome assay. Environ Mol Mutagen (2012) 0.79
A comparative study of protein kinase C activation in gamma-irradiated proliferating and confluent human lung fibroblast cells. J Radiat Res (2009) 0.77
Biochemical response of diverse organs in adult Danio rerio (zebrafish) exposed to sub-lethal concentrations of microcystin-LR and microcystin-RR: a balneation study. Aquat Toxicol (2011) 0.77
MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells. J Nutrigenet Nutrigenomics (2015) 0.77
Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype. Genome Integr (2012) 0.75
Genome Integrity - a new open access journal. Genome Integr (2010) 0.75
Analysis of telomere damage by fluorescence in situ hybridisation on micronuclei in lymphocytes of breast carcinoma patients after radiotherapy. Breast Cancer Res Treat (2007) 0.75