Published in Oncol Rep on May 23, 2013
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Deregulated proliferation and differentiation in brain tumors. Cell Tissue Res (2014) 0.80
Regulation of stem cell function by protein ubiquitylation. EMBO Rep (2014) 0.78
Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma. Oncotarget (2016) 0.77
SAHA and/or MG132 reverse the aggressive phenotypes of glioma cells: An in vitro and vivo study. Oncotarget (2016) 0.75
Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02
Malignant gliomas in adults. N Engl J Med (2008) 20.54
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers. Nature (2007) 5.65
Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin (2010) 5.53
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature (2001) 5.07
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat Rev Mol Cell Biol (2007) 4.49
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell (1997) 4.24
FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res (2007) 3.79
Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res (2007) 3.56
Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma. Cancer (2005) 2.84
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal. Mol Cell Biol (2006) 2.63
Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem (2008) 2.42
Prevalent overexpression of prolyl isomerase Pin1 in human cancers. Am J Pathol (2004) 2.32
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Genes Dev (1998) 2.29
The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. Cancer Res (2003) 2.01
The paradox of response and survival in cancer therapeutics. Blood (2005) 1.63
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. Proc Natl Acad Sci U S A (2010) 1.57
Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas. Histopathology (2011) 1.55
Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase. Mol Cell (2012) 1.48
Downregulation of RUNX3 and TES by hypermethylation in glioblastoma. Oncogene (2006) 1.41
Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J Cell Sci (2003) 1.34
Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells. BMC Cancer (2008) 1.31
Oct4A is expressed by a subpopulation of prostate neuroendocrine cells. Prostate (2009) 1.25
NANOG modulates stemness in human colorectal cancer. Oncogene (2012) 1.19
Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins. J Biol Chem (2009) 1.16
Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification. Nat Clin Pract Cardiovasc Med (2006) 1.15
Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers. Oncogene (2012) 1.13
Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression. Cancer Res (2009) 1.12
Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Mol Cancer (2008) 1.09
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx. J Biol Chem (2007) 1.06
Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation. Nat Cell Biol (2009) 0.99
Expression of NANOG in human gliomas and its relationship with undifferentiated glioma cells. Oncol Rep (2011) 0.96
Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer. Oncogene (2012) 0.93
Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription. Mol Cell Biol (2009) 0.91
High Pin1 expression is associated with tumor progression in colorectal cancer. J Surg Oncol (2006) 0.91
RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. J Cancer Res Clin Oncol (2011) 0.91
Vascular endothelial growth factor is a strong predictor of early distant recurrences in a prospective study of premenopausal women with lymph-node negative breast cancer. Breast (2008) 0.88
Increased Nanog expression promotes tumor development and Cisplatin resistance in human esophageal cancer cells. Cell Physiol Biochem (2012) 0.86
Correlation between glioblastoma stem-like cells and tumor vascularization. Oncol Rep (2011) 0.83
Pin1 acts as a modulator of cell proliferation through alteration in NF-κB but not β-catenin/TCF4 signalling in a subset of endometrial carcinoma cells. J Pathol (2010) 0.80
An immunohistochemical scoring system of prolyl isomerase Pin1 for predicting relapse of prostate carcinoma after radical prostatectomy. Pathol Res Pract (2006) 0.78
MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression. Int J Oncol (2013) 0.96
Gray matter and white matter abnormalities in online game addiction. Eur J Radiol (2013) 0.94
Prefrontal cortex involvement in the event-based prospective memory: evidence from patients with lesions in the prefrontal cortex. Brain Inj (2008) 0.80
Effects of CDNF on 6-OHDA-induced apoptosis in PC12 cells via modulation of Bcl-2/Bax and caspase-3 activation. Neurol Sci (2014) 0.78
Neuronavigation-assisted endoscopic unilateral cyst fenestration for treatment of symptomatic septum pellucidum cysts. J Neurol Surg A Cent Eur Neurosurg (2013) 0.75