Published in Cold Spring Harb Perspect Biol on June 01, 2013
Glycolytic Enzymes Localize to Synapses under Energy Stress to Support Synaptic Function. Neuron (2016) 1.65
Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons. Acta Neuropathol Commun (2015) 1.45
Mitochondrial trafficking and anchoring in neurons: New insight and implications. J Cell Biol (2014) 1.41
Transfer RNA and human disease. Front Genet (2014) 1.35
Bidirectional cargo transport: moving beyond tug of war. Nat Rev Mol Cell Biol (2014) 1.32
Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase. Cell (2014) 1.21
Shaping the dynamic mitochondrial network. BMC Biol (2014) 1.08
Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons. J Neurosci (2014) 1.03
A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation. Nat Cell Biol (2016) 1.02
Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease. Proc Natl Acad Sci U S A (2014) 0.99
Neuronal activity and glutamate uptake decrease mitochondrial mobility in astrocytes and position mitochondria near glutamate transporters. J Neurosci (2014) 0.97
Nutrient-driven O-GlcNAc cycling - think globally but act locally. J Cell Sci (2014) 0.96
Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. J Clin Invest (2015) 0.95
PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease. FEBS J (2014) 0.94
Mitochondria in lung diseases. Expert Rev Respir Med (2013) 0.93
Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion. Mol Cell (2014) 0.93
The dynein inhibitor Ciliobrevin D inhibits the bidirectional transport of organelles along sensory axons and impairs NGF-mediated regulation of growth cones and axon branches. Dev Neurobiol (2014) 0.92
Unique function of Kinesin Kif5A in localization of mitochondria in axons. J Neurosci (2014) 0.91
Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons. Proc Natl Acad Sci U S A (2014) 0.88
Altered serine/threonine kinase activity in schizophrenia. Brain Res (2014) 0.88
Reciprocal Regulation of Mitochondrial Dynamics and Calcium Signaling in Astrocyte Processes. J Neurosci (2015) 0.88
Astroglial glutamate transporters coordinate excitatory signaling and brain energetics. Neurochem Int (2016) 0.86
The intricate relationship between microtubules and their associated motor proteins during axon growth and maintenance. Neural Dev (2013) 0.86
Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling. J Neurosci (2015) 0.86
Preserve and protect: maintaining axons within functional circuits. Trends Neurosci (2014) 0.86
Low-level light in combination with metabolic modulators for effective therapy of injured brain. J Cereb Blood Flow Metab (2015) 0.85
Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease. Oxid Med Cell Longev (2015) 0.84
Potential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies. Curr Neuropharmacol (2016) 0.83
Mitophagy and the mitochondrial unfolded protein response in neurodegeneration and bacterial infection. BMC Biol (2015) 0.83
Quality Saving Mechanisms of Mitochondria during Aging in a Fully Time-Dependent Computational Biophysical Model. PLoS One (2016) 0.83
Mitochondrial dysfunction: different routes to Alzheimer's disease therapy. Oxid Med Cell Longev (2014) 0.82
Role of asymmetric cell division in lifespan control in Saccharomyces cerevisiae. FEMS Yeast Res (2014) 0.81
Miro1 deficiency in amyotrophic lateral sclerosis. Front Aging Neurosci (2015) 0.81
Cellular and subcellular oxidative stress parameters following severe spinal cord injury. Redox Biol (2015) 0.79
The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration. Neuron (2016) 0.79
Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking. Elife (2016) 0.79
Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity. J Biol Chem (2015) 0.79
KIF5A mutations cause an infantile onset phenotype including severe myoclonus with evidence of mitochondrial dysfunction. Ann Neurol (2016) 0.79
Mitochondrial fission augments capsaicin-induced axonal degeneration. Acta Neuropathol (2014) 0.79
Role of protein kinase A in regulating mitochondrial function and neuronal development: implications to neurodegenerative diseases. Rev Neurosci (2015) 0.79
Abnormal intermediate filament organization alters mitochondrial motility in giant axonal neuropathy fibroblasts. Mol Biol Cell (2015) 0.78
Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences. Front Neurosci (2015) 0.78
Parkin suppresses Drp1-independent mitochondrial division. Biochem Biophys Res Commun (2016) 0.77
Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons. J Cell Sci (2015) 0.77
Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3. Elife (2015) 0.77
The Interplay of Axonal Energy Homeostasis and Mitochondrial Trafficking and Anchoring. Trends Cell Biol (2017) 0.77
Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis. Transl Neurodegener (2015) 0.77
Mitochondria-cytoskeleton associations in mammalian cytokinesis. Cell Div (2016) 0.77
BDNF pro-peptide regulates dendritic spines via caspase-3. Cell Death Dis (2016) 0.77
Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons. Elife (2017) 0.77
Disabling mitochondrial reprogramming in cancer. Pharmacol Res (2015) 0.76
Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission. Virology (2016) 0.76
Actin filaments as dynamic reservoirs for Drp1 recruitment. Mol Biol Cell (2016) 0.76
Activity-dependent degeneration of axotomized neuromuscular synapses in Wld S mice. Neuroscience (2015) 0.76
Targeted Mutagenesis of Duplicated Genes in Caenorhabditis elegans Using CRISPR-Cas9. J Genet Genomics (2016) 0.75
Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy. Hum Mol Genet (2016) 0.75
P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway. PLoS One (2014) 0.75
Altered Cytoskeleton as a Mitochondrial Decay Signature in the Retinal Pigment Epithelium. Protein J (2016) 0.75
Methodological advances in imaging intravital axonal transport. F1000Res (2017) 0.75
Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes. Elife (2016) 0.75
Biosynthesis of glycerol phosphate is associated with long-term potentiation in hippocampal neurons. Metabolomics (2016) 0.75
HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging. Neuropharmacology (2017) 0.75
Developmental changes in trak-mediated mitochondrial transport in neurons. Mol Cell Neurosci (2017) 0.75
In vivo Imaging of Mitochondrial Transport in Single-Axon Regeneration of Zebrafish Mauthner Cells. Front Cell Neurosci (2017) 0.75
Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. Neuron (2017) 0.75
Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes. J Neurosci (2016) 0.75
Comparison of Glutamate Turnover in Nerve Terminals and Brain Tissue During [1,6-(13)C2]Glucose Metabolism in Anesthetized Rats. Neurochem Res (2016) 0.75
68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment. Front Aging Neurosci (2017) 0.75
Loss of forebrain MTCH2 decreases mitochondria motility and calcium handling and impairs hippocampal-dependent cognitive functions. Sci Rep (2017) 0.75
Paclitaxel-induced increase in mitochondrial volume mediates dysregulation of intracellular Ca(2+) in putative nociceptive glabrous skin neurons from the rat. Cell Calcium (2017) 0.75
Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration. Mol Biol Cell (2017) 0.75
An emerging role for mitochondrial dynamics in schizophrenia. Schizophr Res (2017) 0.75
Reduction of organelle motility by removal of potassium and other solutes. PLoS One (2017) 0.75
TNFα Decreases Mitochondrial Movement in Human Airway Smooth Muscle. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity. PLoS One (2017) 0.75
Protocols for assessing mitophagy in neuronal cell lines and primary neurons. Neuromethods (2017) 0.75
Accumulating Evidence for Axonal Translation in Neuronal Homeostasis. Front Neurosci (2017) 0.75
A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans. Front Neurosci (2017) 0.75
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature (1998) 21.49
Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (2004) 15.91
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science (1996) 15.88
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature (2006) 11.91
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature (2006) 11.81
Mechanisms of mitophagy. Nat Rev Mol Cell Biol (2011) 10.66
The molecular motor toolbox for intracellular transport. Cell (2003) 9.97
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A (2003) 7.57
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet (2004) 7.45
The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A (2008) 7.41
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell (2011) 5.98
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol (2010) 5.94
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci U S A (2006) 5.78
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell (2004) 5.67
Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method. J Cell Biol (1982) 5.51
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J (1997) 5.03
Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans. Cell (1991) 4.78
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet (2011) 4.41
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell (1998) 4.35
Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell (2007) 4.30
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol (2006) 4.28
The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility. Cell (2009) 4.26
KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell (1994) 4.17
Role of axonal transport in neurodegenerative diseases. Annu Rev Neurosci (2008) 4.09
The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron (2005) 3.71
Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics (1996) 3.56
Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron (2002) 3.52
Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron (2009) 3.49
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One (2010) 3.16
Axonal mitochondrial transport and potential are correlated. J Cell Sci (2004) 3.15
Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit. J Cell Biol (2004) 3.12
Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase. Proc Natl Acad Sci U S A (2008) 3.04
Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell (2008) 2.93
The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking. Biochem Biophys Res Commun (2006) 2.63
The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth. J Cell Sci (1993) 2.63
Imaging axonal transport of mitochondria in vivo. Nat Methods (2007) 2.60
Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem (2002) 2.56
Glutamate decreases mitochondrial size and movement in primary forebrain neurons. J Neurosci (2003) 2.56
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex. J Neurosci (2010) 2.55
Moving mitochondria: establishing distribution of an essential organelle. Traffic (2007) 2.44
Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J Cell Biol (2004) 2.42
Defect in synaptic vesicle precursor transport and neuronal cell death in KIF1A motor protein-deficient mice. J Cell Biol (1998) 2.40
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry (2009) 2.38
Nerve growth factor signaling regulates motility and docking of axonal mitochondria. Curr Biol (2004) 2.37
Mitochondrial trafficking to synapses in cultured primary cortical neurons. J Neurosci (2006) 2.26
Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics. EMBO J (2009) 2.11
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport. Nat Neurosci (2006) 2.11
Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harb Perspect Biol (2012) 2.10
In situ localization of mitochondrial DNA replication in intact mammalian cells. J Cell Biol (1996) 2.01
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet (2012) 2.01
Flying through the drosophila cytoskeletal genome. J Cell Biol (2000) 1.96
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin. Nat Neurosci (2009) 1.95
Mitochondrial movement and positioning in axons: the role of growth factor signaling. J Exp Biol (2003) 1.92
Mitochondrial GTPase mitofusin 2 mutation in Charcot-Marie-Tooth neuropathy type 2A. Hum Genet (2004) 1.91
A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. Nat Neurosci (2007) 1.89
Local translation of extranuclear lamin B promotes axon maintenance. Cell (2012) 1.79
Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Mol Biol Cell (2007) 1.76
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. J Biol Chem (2005) 1.72
The PINK1/Parkin pathway: a mitochondrial quality control system? J Bioenerg Biomembr (2009) 1.72
A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J (2004) 1.71
Movement of mitochondria in the axons and dendrites of cultured hippocampal neurons. J Comp Neurol (2000) 1.69
Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function. J Cell Biol (2000) 1.64
HDAC6 regulates mitochondrial transport in hippocampal neurons. PLoS One (2010) 1.63
Syntabulin-mediated anterograde transport of mitochondria along neuronal processes. J Cell Biol (2005) 1.60
Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase. J Biol Chem (2002) 1.60
TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. Neuron (2013) 1.60
Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport. J Neurosci (2009) 1.57
Mitochondrial dynamics and Ca2+ signaling. Biochim Biophys Acta (2006) 1.57
A specific light chain of kinesin associates with mitochondria in cultured cells. Mol Biol Cell (1998) 1.51
Mitochondrial membrane potential in axons increases with local nerve growth factor or semaphorin signaling. J Neurosci (2008) 1.51
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. J Cell Biol (2004) 1.49
Mitochondrial dynamics and peripheral neuropathy. Neuroscientist (2007) 1.43
Mechanisms of mitochondria-neurofilament interactions. J Neurosci (2003) 1.41
Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons. J Comp Neurol (2000) 1.39
Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function. Traffic (2007) 1.35
Mitochondrial biogenesis in the axons of vertebrate peripheral neurons. Dev Neurobiol (2008) 1.32
Mapping the GRIF-1 binding domain of the kinesin, KIF5C, substantiates a role for GRIF-1 as an adaptor protein in the anterograde trafficking of cargoes. J Biol Chem (2006) 1.32
High resolution imaging of live mitochondria. Biochim Biophys Acta (2006) 1.29
Mitochondria are redistributed in Drosophila photoreceptors lacking milton, a kinesin-associated protein. J Comp Neurol (2003) 1.28
Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria. J Neurosci (2010) 1.28
Plectin isoform 1b mediates mitochondrion-intermediate filament network linkage and controls organelle shape. J Cell Biol (2008) 1.28
Milton controls the early acquisition of mitochondria by Drosophila oocytes. Development (2006) 1.27
Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons. J Biol Chem (2011) 1.26
Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases. Exp Cell Res (2007) 1.25
Association of mitochondria with plectin and desmin intermediate filaments in striated muscle. Exp Cell Res (1999) 1.24
Myelination and axonal electrical activity modulate the distribution and motility of mitochondria at CNS nodes of Ranvier. J Neurosci (2011) 1.23
Regulation of mitochondria distribution by RhoA and formins. J Cell Sci (2006) 1.22
Local synthesis of nuclear-encoded mitochondrial proteins in the presynaptic nerve terminal. J Neurosci Res (2001) 1.22
O-GlcNAc cycling: implications for neurodegenerative disorders. Int J Biochem Cell Biol (2009) 1.22
Plectin 5'-transcript diversity: short alternative sequences determine stability of gene products, initiation of translation and subcellular localization of isoforms. Hum Mol Genet (2003) 1.21
Identification, molecular cloning, and characterization of a novel GABAA receptor-associated protein, GRIF-1. J Biol Chem (2002) 1.20
Vimentin intermediate filaments modulate the motility of mitochondria. Mol Biol Cell (2011) 1.18
Human Myo19 is a novel myosin that associates with mitochondria. Curr Biol (2009) 1.14
ADP regulates movements of mitochondria in neurons. Biophys J (2007) 1.13
KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome. Development (2008) 1.13
Quantitative imaging of energy expenditure in human brain. Neuroimage (2012) 1.09
Regulation of axonal trafficking of cytochrome c oxidase IV mRNA. Mol Cell Neurosci (2010) 1.09
GRIF1 binds Hrs and is a new regulator of endosomal trafficking. J Cell Sci (2006) 1.07
A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. J Neurosci (1998) 1.06