Published in J Neurosci on August 13, 2008
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J Cell Biol (2014) 2.95
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci (2012) 2.68
The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ (2012) 2.45
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
Mitochondrial dynamics regulates migration and invasion of breast cancer cells. Oncogene (2012) 1.69
Mitochondrial trafficking in neurons. Cold Spring Harb Perspect Biol (2013) 1.69
Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies. Biomark Med (2010) 1.69
Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr Biol (2012) 1.64
Mitochondrial trafficking and anchoring in neurons: New insight and implications. J Cell Biol (2014) 1.41
Mitochondrial transport and docking in axons. Exp Neurol (2009) 1.41
Nerve growth factor induces axonal filopodia through localized microdomains of phosphoinositide 3-kinase activity that drive the formation of cytoskeletal precursors to filopodia. J Neurosci (2010) 1.39
Mitochondria and neuroplasticity. ASN Neuro (2010) 1.36
Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria. J Neurosci (2010) 1.28
PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J Neurosci (2011) 1.24
Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis. Cell Rep (2013) 1.23
Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration. J Neurosci (2012) 1.18
Ageing and Parkinson's disease: why is advancing age the biggest risk factor? Ageing Res Rev (2014) 1.17
Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms. Pharmacol Ther (2012) 1.15
Mitochondrial matrix Ca2+ as an intrinsic signal regulating mitochondrial motility in axons. Proc Natl Acad Sci U S A (2011) 1.12
Mitochondrial localized STAT3 is involved in NGF induced neurite outgrowth. PLoS One (2011) 1.10
Regulation of mitochondrial transport in neurons. Exp Cell Res (2015) 1.06
The role of mitochondrially derived ATP in synaptic vesicle recycling. J Biol Chem (2015) 0.98
p75NTR-dependent modulation of cellular handling of reactive oxygen species. J Neurochem (2009) 0.97
Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxia. J Neurosci (2010) 0.97
The dynamics of the mitochondrial organelle as a potential therapeutic target. J Cereb Blood Flow Metab (2012) 0.94
The Organization of Mitochondrial Quality Control and Life Cycle in the Nervous System In Vivo in the Absence of PINK1. J Neurosci (2015) 0.92
Drp1-mediated mitochondrial dynamics and survival of developing chick motoneurons during the period of normal programmed cell death. FASEB J (2012) 0.87
The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro (2009) 0.87
Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo. PLoS One (2009) 0.87
Mitochondrial dynamics regulate growth cone motility, guidance, and neurite growth rate in perinatal retinal ganglion cells in vitro. Invest Ophthalmol Vis Sci (2012) 0.86
Induction of caspase 3 activation by multiple Legionella pneumophila Dot/Icm substrates. Cell Microbiol (2013) 0.85
From structure to function: mitochondrial morphology, motion and shaping in vascular smooth muscle. J Vasc Res (2013) 0.84
Mitochondrial protein quality control in health and disease. Br J Pharmacol (2014) 0.84
Compartmentalized Regulation of Parkin-Mediated Mitochondrial Quality Control in the Drosophila Nervous System In Vivo. J Neurosci (2016) 0.82
FUS Interacts with HSP60 to Promote Mitochondrial Damage. PLoS Genet (2015) 0.82
The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone. Exp Cell Res (2012) 0.81
Mitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer's Disease. Pharmaceuticals (Basel) (2012) 0.81
Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning. J Neurochem (2012) 0.81
Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia. Pain (2011) 0.80
The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration. Neuron (2016) 0.79
Mitochondrial fission augments capsaicin-induced axonal degeneration. Acta Neuropathol (2014) 0.79
Progressive Decrease of Mitochondrial Motility during Maturation of Cortical Axons In Vitro and In Vivo. Curr Biol (2016) 0.79
Mitochondria Localize to Injured Axons to Support Regeneration. Neuron (2016) 0.78
CSPGs inhibit axon branching by impairing mitochondria-dependent regulation of actin dynamics and axonal translation. Dev Neurobiol (2016) 0.76
Dynamics of Mitochondrial Transport in Axons. Front Cell Neurosci (2016) 0.76
Nerve growth factor alters microtubule targeting agent-induced neurotransmitter release but not MTA-induced neurite retraction in sensory neurons. Exp Neurol (2016) 0.75
Knockout of Cyclophilin-D Provides Partial Amelioration of Intrinsic and Synaptic Properties Altered by Mild Traumatic Brain Injury. Front Syst Neurosci (2016) 0.75
Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission-fusion balance within mitochondrial networks. Nat Commun (2016) 0.75
FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep (2016) 0.75
Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. Neuron (2017) 0.75
Chondroitin Sulfate Proteoglycans Negatively Regulate the Positioning of Mitochondria and Endoplasmic Reticulum to Distal Axons. Dev Neurobiol (2017) 0.75
Analysis of mitochondrial organization and function in the Drosophila blastoderm embryo. Sci Rep (2017) 0.75
Respiratory enzymes in oxidative phosphorylation. III. The steady state. J Biol Chem (1955) 7.56
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell (2004) 7.45
Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci U S A (1980) 7.31
Synapses in the central nervous system. J Biophys Biochem Cytol (1956) 6.63
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A (1991) 5.78
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys J (1999) 5.05
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron (2005) 4.87
Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J Cell Biol (1981) 3.97
Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J Cell Biol (1995) 3.74
Mitochondria and neuronal survival. Physiol Rev (2000) 3.56
AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest (2006) 3.39
Axonal mitochondrial transport and potential are correlated. J Cell Sci (2004) 3.15
Membrane potential can be determined in individual cells from the nernstian distribution of cationic dyes. Biophys J (1988) 2.90
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. EMBO J (2002) 2.70
Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins. Proc Natl Acad Sci U S A (2007) 2.65
The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth. J Cell Sci (1993) 2.63
OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. Brain (2008) 2.57
Simultaneous imaging of cell and mitochondrial membrane potentials. Biophys J (1989) 2.46
Transient mitochondrial depolarizations reflect focal sarcoplasmic reticular calcium release in single rat cardiomyocytes. J Cell Biol (1998) 2.39
Nerve growth factor signaling regulates motility and docking of axonal mitochondria. Curr Biol (2004) 2.37
Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence. J Biol Chem (2007) 2.22
Growth cone guidance: first steps towards a deeper understanding. Annu Rev Neurosci (1999) 2.06
The distribution of mitochondrial activity in relation to optic nerve structure. Arch Ophthalmol (2002) 2.06
The relationship between mitochondrial state, ATP hydrolysis, [Mg2+]i and [Ca2+]i studied in isolated rat cardiomyocytes. J Physiol (1996) 2.03
Synaptic mitochondria are more susceptible to Ca2+overload than nonsynaptic mitochondria. J Biol Chem (2006) 1.93
Mitochondrial movement and positioning in axons: the role of growth factor signaling. J Exp Biol (2003) 1.92
Localized sources of neurotrophins initiate axon collateral sprouting. J Neurosci (1998) 1.90
Assessment of mitochondrial membrane potential in proximal tubules after hypoxia-reoxygenation. Am J Physiol Renal Physiol (2004) 1.84
Actin-ATP hydrolysis is a major energy drain for neurons. J Neurosci (2003) 1.73
A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons. EMBO J (2004) 1.71
Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons. J Cell Sci (1996) 1.68
Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci (2000) 1.66
High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition. J Neurosci (2007) 1.65
Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance. Neuron (1999) 1.65
Characterization of the turning response of dorsal root neurites toward nerve growth factor. J Cell Biol (1980) 1.64
In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem (2004) 1.57
The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor. J Cell Biol (1993) 1.55
PTEN couples Sema3A signalling to growth cone collapse. J Cell Sci (2006) 1.54
Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord. J Neurosci (2006) 1.51
The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor. J Neurosci (1997) 1.42
Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794. J Biol Chem (2007) 1.41
Spontaneous changes in mitochondrial membrane potential in cultured neurons. J Neurosci (2001) 1.41
Response of mitochondrial traffic to axon determination and differential branch growth. J Neurosci (2003) 1.37
Regulation of growth cone behavior by calcium: new dynamics to earlier perspectives. J Neurobiol (2000) 1.32
Quantitative analysis of spontaneous mitochondrial depolarizations. Biophys J (2003) 1.30
AMP-activated protein kinase kinase: detection with recombinant AMPK alpha1 subunit. Biochem Biophys Res Commun (2002) 1.29
Cellular localization of nerve growth factor synthesis by in situ hybridization. EMBO J (1987) 1.28
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Mol Cell Proteomics (2007) 1.27
Expression of phosphatidylinositol (4,5) bisphosphate-specific pleckstrin homology domains alters direction but not the level of axonal transport of mitochondria. Mol Biol Cell (2003) 1.26
Tyrosine phosphorylation in mitochondria: a new frontier in mitochondrial signaling. Free Radic Biol Med (2005) 1.23
Mitoenergetic failure in Alzheimer disease. Am J Physiol Cell Physiol (2006) 1.22
Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: inhibition of alpha-ketoglutarate dehydrogenase. J Neurochem (1999) 1.19
Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons. Mol Cell Neurosci (2005) 1.15
Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria. Biophys J (2003) 1.14
Subcellular heterogeneity of mitochondrial function and dysfunction: evidence obtained by confocal imaging. Mol Cell Biochem (2004) 1.11
Axoplasmic organelles at nodes of Ranvier. I. Occurrence and distribution in large myelinated spinal root axons of the adult cat. J Neurocytol (1993) 1.10
Control of semaphorin signaling. Curr Opin Neurobiol (2002) 1.10
Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: enzyme and substrate characterization and functional role. Biochemistry (2001) 1.08
Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. J Neurosci (2003) 1.07
A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. J Neurosci (1998) 1.06
Calcium signalling in growth cone migration. Cell Calcium (2005) 1.05
The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor. Biochemistry (1993) 1.05
Homogeneous longitudinal profiles and synchronous fluctuations of mitochondrial transmembrane potential. FEBS Lett (2000) 1.03
Zn2+ inhibits mitochondrial movement in neurons by phosphatidylinositol 3-kinase activation. J Neurosci (2005) 1.02
Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation. J Neurochem (2003) 1.00
Responses of growth cones to changes in osmolality of the surrounding medium. J Cell Sci (1991) 1.00
Growth cones integrate signaling from multiple guidance cues. J Histochem Cytochem (2003) 0.98
Fluorescence imaging of metabolic responses in single mitochondria. Biochem Biophys Res Commun (2002) 0.98
Nerve growth factor (NGF) influences differentiation and proliferation of myogenic cells in vitro via TrKA. Int J Dev Neurosci (2000) 0.97
Focal accumulation of intra-axonal mitochondria in demyelination of the cat optic nerve. Acta Neuropathol (1998) 0.95
Mechanisms of axon guidance: membrane dynamics and axonal transport in semaphorin signalling. J Neurochem (2007) 0.92
Nerve growth factor, glial cell line-derived neurotrophic factor and neurturin prevent semaphorin 3A-mediated growth cone collapse in adult sensory neurons. Neuroscience (2006) 0.91
Plasma membrane recycling and flow in growing neurites. Neuroscience (2000) 0.88
Protein synthesizing units in presynaptic and postsynaptic domains of squid neurons. J Cell Sci (1998) 0.85
Mitochondria consume energy and compromise cellular membrane potential by reversing ATP synthetase activity during focal ischemia in rats. J Cereb Blood Flow Metab (2004) 0.85
Growing and working with peripheral neurons. Methods Cell Biol (2003) 0.83
Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease. Neurobiol Aging (2005) 0.83
Determination of resting membrane potential of individual neuroblastoma cells (IMR-32) using a potentiometric dye (TMRM) and confocal microscopy. J Fluoresc (2004) 0.82
Comparing the properties of neuronal culture systems: a shopping guide for the cell biologist. Methods Cell Biol (2003) 0.81
Mitochondrial heterogeneity within and between different cell types. Neurochem Res (2004) 0.79
Localization of nerve growth factor receptors in sympathetic neurons cultured in vitro. Brain Res (1979) 0.78
Functional characterization of calcium channels localized on the growth cones of cultured rat dorsal root ganglion cells. Neurosci Lett (2002) 0.77
Nerve growth factor signaling regulates motility and docking of axonal mitochondria. Curr Biol (2004) 2.37
Mitochondrial movement and positioning in axons: the role of growth factor signaling. J Exp Biol (2003) 1.92
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
Response of mitochondrial traffic to axon determination and differential branch growth. J Neurosci (2003) 1.37
Mitochondrial biogenesis in the axons of vertebrate peripheral neurons. Dev Neurobiol (2008) 1.32
Organization and translation of mRNA in sympathetic axons. J Cell Sci (2003) 1.31
Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria. J Neurosci (2010) 1.28
Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxia. J Neurosci (2010) 0.97
Transfection of primary central and peripheral nervous system neurons by electroporation. Methods Cell Biol (2003) 0.86
Legionella pneumophila infection of Drosophila S2 cells induces only minor changes in mitochondrial dynamics. PLoS One (2013) 0.75
Exploring the life cycle of mitochondria in neuropsychiatric diseases: mitochondrial dynamics and quality control. Neurobiol Dis (2012) 0.75
How to get on the right track. Nat Neurosci (2011) 0.75
Peter J. Hollenbeck. Curr Biol (2010) 0.75