Published in Org Biomol Chem on July 21, 2013
Using 5-deoxy-5-[18F]fluororibose to glycosylate peptides for positron emission tomography. Nat Protoc (2013) 0.79
Sweetening pharmaceutical radiochemistry by (18)f-fluoroglycosylation: a short review. Biomed Res Int (2014) 0.78
Fluorine-18 patents (2009-2015). Part 2: new radiochemistry. Pharm Pat Anal (2016) 0.75
Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1. Biochem J (2002) 2.16
Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis. PLoS Biol (2011) 1.92
Crystal structure and mechanism of a bacterial fluorinating enzyme. Nature (2004) 1.70
Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide. J Nat Prod (2010) 1.39
Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study. Am J Clin Nutr (2013) 1.39
Analysis of CF···FC interactions on cyclohexane and naphthalene frameworks. J Phys Chem A (2014) 1.39
Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China. Cancer Prev Res (Phila) (2011) 1.37
The observation of a large gauche preference when 2-fluoroethylamine and 2-fluoroethanol become protonated. Org Biomol Chem (2004) 1.30
The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A. Chem Biol (2006) 1.27
Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity. J Mol Biol (2007) 1.13
The fluorinase from Streptomyces cattleya is also a chlorinase. Angew Chem Int Ed Engl (2006) 1.13
Catalytic asymmetric fluorination comes of age. Angew Chem Int Ed Engl (2008) 1.13
Dimerizable redox-sensitive triazine-based cationic lipids for in vitro gene delivery. ChemMedChem (2007) 1.12
Recommendations for measurement of tumour vascularity with positron emission tomography in early phase clinical trials. Eur Radiol (2012) 1.09
In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase. Chem Biol (2008) 1.09
Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis. Proc Natl Acad Sci U S A (2014) 1.06
Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya. FEBS Lett (2003) 1.06
Molecular insights into bacteroid development during Rhizobium-legume symbiosis. FEMS Microbiol Rev (2013) 1.04
Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya. Nat Prod Rep (2004) 1.04
The fluorine gauche effect. Langmuir isotherms report the relative conformational stability of (+/-)-erythro- and (+/-)-threo-9,10-difluorostearic acids. Chem Commun (Camb) (2002) 1.03
Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy. Biochem J (2004) 1.02
Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism. Chembiochem (2004) 1.00
The fluorinase, the chlorinase and the duf-62 enzymes. Curr Opin Chem Biol (2008) 0.99
Alicyclic ring structure: conformational influence of the CF2 group in cyclododecanes. Angew Chem Int Ed Engl (2011) 0.98
Mechanism of enzymatic fluorination in Streptomyces cattleya. J Am Chem Soc (2007) 0.98
Egr1 signaling in prostate cancer. Cancer Biol Ther (2003) 0.98
Synthesis and structure of all-syn-1,2,3,4-tetrafluorocyclohexane. Chem Commun (Camb) (2011) 0.97
Synthesis and structure of stereoisomeric multivicinal hexafluoroalkanes. Angew Chem Int Ed Engl (2009) 0.97
Enantioselective synthesis of an all-syn four vicinal fluorine motif. J Am Chem Soc (2006) 0.96
The identification of 5'-fluoro-5-deoxyinosine as a shunt product in cell free extracts of Streptomyces cattleya. Bioorg Chem (2005) 0.95
alpha,beta,gamma-Trifluoroalkanes: a stereoselective synthesis placing three vicinal fluorines along a hydrocarbon chain. J Am Chem Soc (2005) 0.95
Prins fluorination cyclisations: Preparation of 4-fluoro-pyran and -piperidine heterocycles. Beilstein J Org Chem (2010) 0.93
Insight into enzymatic C-F bond formation from QM and QM/MM calculations. J Am Chem Soc (2005) 0.93
Accelerating influence of the gem-difluoromethylene group in a ring-closing olefin metathesis reaction. A Thorpe-Ingold effect? Chem Commun (Camb) (2013) 0.92
Astrocytes shed large membrane vesicles that contain mitochondria, lipid droplets and ATP. Histochem Cell Biol (2012) 0.92
Role of cysteine residues and disulfide bonds in the activity of a legume root nodule-specific, cysteine-rich peptide. J Biol Chem (2012) 0.91
Synthesis and elaboration of all-cis-1,2,4,5-tetrafluoro-3-phenylcyclohexane: a polar cyclohexane motif. Chemistry (2014) 0.91
Preparation of (R)-Fluoropyruvaldehyde N,S-Ketals by Highly Stereospecific Tandem Pummerer Rearrangement/1,2-p-Tolylthio Group Migration of (R)-alpha-(Fluoroalkyl)-beta-sulfinylenamines. J Org Chem (1997) 0.90
Fluorinase mediated C-(18)F bond formation, an enzymatic tool for PET labelling. Chem Commun (Camb) (2006) 0.90
Avirulence protein 3a (AVR3a) from the potato pathogen Phytophthora infestans forms homodimers through its predicted translocation region and does not specifically bind phospholipids. J Biol Chem (2012) 0.90
One-step synthesis of O-benzyl hydroxamates from unactivated aliphatic and aromatic esters. J Org Chem (2005) 0.89
S-adenosyl-L-methionine:hydroxide adenosyltransferase: a SAM enzyme. Angew Chem Int Ed Engl (2008) 0.89
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells. Biochem J (2004) 0.89
Fluorocyclohexanes: synthesis and structure of all-syn-1,2,4,5-tetrafluorocyclohexane. Chem Commun (Camb) (2012) 0.88
Synthesis, structure and conformation of partially-modified retro- and retro-inverso psi[NHCH(CF3)]Gly peptides. Chemistry (2003) 0.87
Stereoelectronic interactions and the one-bond C-F coupling constant in sevoflurane. J Phys Chem A (2012) 0.86
Multi-vicinal fluoroalkanes: a new class of organofluorine compounds. Org Biomol Chem (2008) 0.86
Total synthesis of tubulysins U and V. Angew Chem Int Ed Engl (2007) 0.86
Hypoxia stimulates 18F-fluorodeoxyglucose uptake in breast cancer cells via hypoxia inducible factor-1 and AMP-activated protein kinase. Nucl Med Biol (2013) 0.86
Diastereoselective synthesis of 2,3,4,5,6-pentafluoroheptanes. J Org Chem (2009) 0.85
Response to trastuzumab by HER2 expressing breast tumour xenografts is accompanied by decreased Hexokinase II, glut1 and [18F]-FDG incorporation and changes in 31P-NMR-detectable phosphomonoesters. Cancer Chemother Pharmacol (2012) 0.85
Fluorinase-coupled base swaps: synthesis of [18F]-5'-deoxy-5'-fluorouridines. Angew Chem Int Ed Engl (2008) 0.85
Fluorine containing amino acids: synthesis and peptide coupling of amino acids containing the all-cis tetrafluorocyclohexyl motif. Org Biomol Chem (2015) 0.85
Synthesis and conformation of multi-vicinal fluoroalkane diastereoisomers. Angew Chem Int Ed Engl (2007) 0.85
Liquid crystals carrying stereodefined vicinal difluoro- and trifluoro- alkyl motifs. Chem Commun (Camb) (2007) 0.85
Fluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA. Org Biomol Chem (2011) 0.85
Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews. Angew Chem Int Ed Engl (2001) 0.84
Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. Chemosphere (2003) 0.84
Stepwise preparation of all-cis 1,3,4-trifluoro-2-phenylcyclohexane, avoiding a phenonium intermediate. J Org Chem (2014) 0.84
An electrostatic gauche effect in beta-fluoro- and beta-hydroxy-N-ethylpyridinium cations. Angew Chem Int Ed Engl (2007) 0.84
Cloning, characterization and regulation of a family of phi class glutathione transferases from wheat. Plant Mol Biol (2003) 0.84
Synthesis of phosphonate and phostone analogues of ribose-1-phosphates. Beilstein J Org Chem (2009) 0.83
Cell-free biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. Angew Chem Int Ed Engl (2002) 0.83
The rare fluorinated natural products and biotechnological prospects for fluorine enzymology. Methods Enzymol (2012) 0.83
Efforts toward the total synthesis of tubulysins: new hopes for a more effective targeted drug delivery to tumors. ChemMedChem (2006) 0.82
Identification of 5-fluoro-5-deoxy-D-ribose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya. Chem Commun (Camb) (2004) 0.82
Replacement of isobutyl by trifluoromethyl in pepstatin A selectively affects inhibition of aspartic proteinases. Chembiochem (2006) 0.82
Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates. Org Biomol Chem (2006) 0.81
An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids. Small (2010) 0.81
Fluorosugars: synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of D-glucose and D-altrose and assessment of their erythrocyte transmembrane transport. Chem Commun (Camb) (2010) 0.81
The pine-cone body: an intermediate structure between the cap mesenchyme and the renal vesicle in the developing nod mouse kidney revealed by an ultrastructural study. J Matern Fetal Neonatal Med (2012) 0.81
Synthesis and vanilloid receptor (TRPV1) activity of the enantiomers of alpha-fluorinated capsaicin. Chembiochem (2009) 0.81
The identification of (3R,4S)-5-fluoro-5-deoxy-D-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya. Bioorg Chem (2007) 0.81
An enzymatic route to 5-deoxy-5-[18F]fluoro-D-ribose, a [18F]-fluorinated sugar for PET imaging. Chem Commun (Camb) (2009) 0.80
Crystallization and X-ray diffraction of 5'-fluoro-5'-deoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya. Acta Crystallogr D Biol Crystallogr (2003) 0.80
The mechanisms of radical SAM/cobalamin methylations: an evolving working hypothesis. Chembiochem (2013) 0.80
Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants. Bioorg Chem (2012) 0.80
[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging. Chem Commun (Camb) (2012) 0.80
Chemoselective C-4 aerobic oxidation of catechin derivatives catalyzed by the Trametes villosa laccase/1-hydroxybenzotriazole system: synthetic and mechanistic aspects. J Org Chem (2011) 0.80
Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62). Chembiochem (2009) 0.80
Efficient cell transfection with melamine-based gemini surfactants. Bioconjug Chem (2013) 0.80
New fluorinated peptidomimetics through tandem aza-michael addition to alpha-trifluoromethyl acrylamide acceptors: synthesis and conformational study in solid state and solution. J Org Chem (2009) 0.80
Assessing the bioisosterism of the trifluoromethyl group with a protease probe. ChemMedChem (2009) 0.80
A dimerizable cationic lipid with potential for gene delivery. J Gene Med (2008) 0.79
Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet. Org Biomol Chem (2012) 0.79
Polar alicyclic rings: synthesis and structure of all cis-1,2,3,4-tetrafluorocyclopentane. Chem Commun (Camb) (2016) 0.79
The multi-vicinal fluoroalkane motif: an examination of 2,3,4,5-tetrafluorohexane stereoisomers. Org Biomol Chem (2008) 0.79
Synthesis, conformation and biological evaluation of the enantiomers of 3-fluoro-gamma-aminobutyric acid ((R)- and (S)-3F-GABA): an analogue of the neurotransmitter GABA. Chembiochem (2007) 0.79
Highly stereoselective tandem aza-Michael addition-enolate protonation to form partially modified retropeptide mimetics incorporating a trifluoroalanine surrogate. Angew Chem Int Ed Engl (2003) 0.79
Multicomponent reactions of methyl substituted all-cis tetrafluorocyclohexane aldehydes. Org Biomol Chem (2015) 0.79
Enantiomers of 4-amino-3-fluorobutanoic acid as substrates for gamma-aminobutyric acid aminotransferase. Conformational probes for GABA binding. Biochemistry (2007) 0.79
The yin of exofacial protein sulfhydryls and the yang of intracellular glutathione in in vitro transfection with SS14 bioreducible lipoplexes. J Control Release (2012) 0.79
Mechanistic insights into the cytochrome P450-mediated oxidation and rearrangement of littorine in tropane alkaloid biosynthesis. Chembiochem (2009) 0.79
Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors. Bioorg Med Chem Lett (2009) 0.79
3-Fluoro-N-methyl-D-aspartic acid (3F-NMDA) stereoisomers as conformational probes for exploring agonist binding at NMDA receptors. Chemistry (2012) 0.79