Published in Proc Natl Acad Sci U S A on February 25, 2003
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Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics. Genes Dev (2004) 1.97
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E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas. Mol Cell Biol (2003) 1.50
E2F4 loss suppresses tumorigenesis in Rb mutant mice. Cancer Cell (2002) 1.48
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev (2010) 1.47
Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. Mol Cell (2003) 1.47
Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo. Mol Cell Biol (2002) 1.44
The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol Cancer Res (2008) 1.43
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Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Dev Dyn (2009) 1.27
Insulin-like growth factor 2 is required for progression to advanced medulloblastoma in patched1 heterozygous mice. Cancer Res (2008) 1.18
Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells. Mol Syst Biol (2015) 1.11
E2f4 is required for normal development of the airway epithelium. Dev Biol (2007) 1.11
Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. PLoS One (2007) 1.07
Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues. Mol Cell Biol (2007) 1.07
Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences. Proc Natl Acad Sci U S A (2011) 1.04
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Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development (2003) 0.99
Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers. Proc Natl Acad Sci U S A (2010) 0.96
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E2F3 plays an essential role in cardiac development and function. Cell Cycle (2008) 0.94
E2f6 and Bmi1 cooperate in axial skeletal development. Dev Dyn (2008) 0.89
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A (2009) 0.86
Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery. PLoS Genet (2013) 0.84
Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations. Cell Cycle (2010) 0.82
CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity. Proc Natl Acad Sci U S A (2014) 0.82
E2F4 cooperates with pRB in the development of extra-embryonic tissues. Dev Biol (2009) 0.82
pRB and E2F4 play distinct cell-intrinsic roles in fetal erythropoiesis. Cell Cycle (2010) 0.80
Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. Methods Enzymol (2008) 0.76