Published in Nat Rev Mol Cell Biol on June 19, 2013
Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages. Nat Cell Biol (2013) 1.81
The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell (2017) 1.43
Restarting life: fertilization and the transition from meiosis to mitosis. Nat Rev Mol Cell Biol (2013) 1.18
Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Dev Cell (2014) 1.06
Cadherin-dependent filopodia control preimplantation embryo compaction. Nat Cell Biol (2013) 1.04
Limited predictive value of blastomere angle of division in trophectoderm and inner cell mass specification. Development (2014) 0.99
Asymmetric division of contractile domains couples cell positioning and fate specification. Nature (2016) 0.90
Single cells get together: High-resolution approaches to study the dynamics of early mouse development. Semin Cell Dev Biol (2015) 0.84
Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep (2015) 0.84
Transcription factor AP-2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage. Development (2015) 0.83
Origin of cellular asymmetries in the pre-implantation mouse embryo: a hypothesis. Philos Trans R Soc Lond B Biol Sci (2014) 0.80
Dynamic expression of chromatin modifiers during developmental transitions in mouse preimplantation embryos. Sci Rep (2015) 0.77
Bacterial swarms recruit cargo bacteria to pave the way in toxic environments. MBio (2015) 0.77
Generic Theoretical Models to Predict Division Patterns of Cleaving Embryos. Dev Cell (2016) 0.76
The Principal Forces of Oocyte Polarity Are Evolutionary Conserved but May Not Affect the Contribution of the First Two Blastomeres to the Blastocyst Development in Mammals. PLoS One (2016) 0.76
A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis. Elife (2016) 0.75
Chemical reaction networks: Colour by number. Nat Chem (2013) 0.75
Random Allocation of Blastomere Descendants to the Trophectoderm and ICM of the Bovine Blastocyst. Biol Reprod (2016) 0.75
Self-Organizing Global Gene Expression Regulated through Criticality: Mechanism of the Cell-Fate Change. PLoS One (2016) 0.75
Cell Polarity in Cerebral Cortex Development-Cellular Architecture Shaped by Biochemical Networks. Front Cell Neurosci (2017) 0.75
Four simple rules that are sufficient to generate the mammalian blastocyst. PLoS Biol (2017) 0.75
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell (2003) 20.16
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell (1998) 19.05
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72
Nanog safeguards pluripotency and mediates germline development. Nature (2007) 13.01
Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev (2003) 12.38
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell (2010) 12.23
mRNA-Seq whole-transcriptome analysis of a single cell. Nat Methods (2009) 11.71
Imaging individual mRNA molecules using multiple singly labeled probes. Nat Methods (2008) 10.40
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell (1988) 7.72
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature (2008) 7.60
A gradient of bicoid protein in Drosophila embryos. Cell (1988) 7.30
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell (2005) 7.30
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell (2012) 7.17
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature (1984) 6.54
A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell (2010) 6.24
Variability in gene expression underlies incomplete penetrance. Nature (2010) 5.85
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Capturing pluripotency. Cell (2008) 5.08
Developmental patterning by mechanical signals in Arabidopsis. Science (2008) 5.04
Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA-Seq analysis. Cell Stem Cell (2010) 4.97
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development (2005) 4.89
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell (2006) 4.77
Intestinal stem cell replacement follows a pattern of neutral drift. Science (2010) 4.62
Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells. PLoS Biol (2009) 4.60
An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis. Nucleic Acids Res (2006) 4.26
Simulation of the differential adhesion driven rearrangement of biological cells. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (1993) 3.95
Stochastic patterning in the mouse pre-implantation embryo. Development (2007) 3.83
Quantitative high-speed imaging of entire developing embryos with simultaneous multiview light-sheet microscopy. Nat Methods (2012) 3.80
Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development (2009) 3.25
Multiview light-sheet microscope for rapid in toto imaging. Nat Methods (2012) 3.12
Mouse chimaeras developed from fused eggs. Nature (1961) 2.88
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development (2008) 2.88
Surface mechanics mediate pattern formation in the developing retina. Nature (2004) 2.84
Single-molecule transcript counting of stem-cell markers in the mouse intestine. Nat Cell Biol (2011) 2.72
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development (2007) 2.71
Noise can induce bimodality in positive transcriptional feedback loops without bistability. Science (2010) 2.60
FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development (2010) 2.60
First cleavage plane of the mouse egg is not predetermined but defined by the topology of the two apposing pronuclei. Nature (2004) 2.58
Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science (2012) 2.57
Blastocyst axis is specified independently of early cell lineage but aligns with the ZP shape. Science (2007) 2.55
Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system. Dev Cell (2006) 2.52
Alignment between PIN1 polarity and microtubule orientation in the shoot apical meristem reveals a tight coupling between morphogenesis and auxin transport. PLoS Biol (2010) 2.44
The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate. Dev Cell (2010) 2.41
Specification of the anteroposterior axis in Caenorhabditis elegans. Development (1996) 2.35
Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos. Mech Dev (2007) 2.29
Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. Dev Biol (2007) 2.26
The foundation of two distinct cell lineages within the mouse morula. Cell (1981) 2.24
Role for sperm in spatial patterning of the early mouse embryo. Nature (2001) 2.20
Universal patterns of stem cell fate in cycling adult tissues. Development (2011) 2.19
Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage. J Embryol Exp Morphol (1967) 2.15
Self-organization in cell biology: a brief history. Nat Rev Mol Cell Biol (2008) 2.13
Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo. Proc Natl Acad Sci U S A (2010) 2.12
Polarity of the mouse embryo is established at blastocyst and is not prepatterned. Genes Dev (2005) 2.05
Mouse chimeras obtained by the injection of cells into the blastocyst. Nature (1968) 1.99
Mouse germ line stem cells undergo rapid and stochastic turnover. Cell Stem Cell (2010) 1.97
How amoeboids self-organize into a fruiting body: multicellular coordination in Dictyostelium discoideum. Proc Natl Acad Sci U S A (2001) 1.86
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One (2011) 1.82
Formation of the embryonic-abembryonic axis of the mouse blastocyst: relationships between orientation of early cleavage divisions and pattern of symmetric/asymmetric divisions. Development (2008) 1.75
Cytosystems dynamics in self-organization of tissue architecture. Nature (2013) 1.74
An autoregulatory circuit for long-range self-organization in Dictyostelium cell populations. Nature (2005) 1.67
Optimality in the development of intestinal crypts. Cell (2012) 1.67
Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development. Development (2001) 1.66
Four-cell stage mouse blastomeres have different developmental properties. Development (2005) 1.62
[Cell functions and change in cell function in the development of Dictyostelium discoideum. V. Stagespecific cell contact formation and its quantitative evaluation]. Exp Cell Res (1961) 1.54
Experiments on the development of isolated blastomers of mouse eggs. Nature (1959) 1.53
Cell shape and membrane changes in the eight-cell mouse embryo: prerequisites for morphogenesis of the blastocyst. Dev Biol (1975) 1.49
Emerging asymmetry and embryonic patterning in early mouse development. Dev Cell (2004) 1.49
Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst. Dev Biol (2009) 1.48
FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development (2012) 1.47
Specification of embryonic axes begins before cleavage in normal mouse development. Development (2001) 1.44
A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst. Dev Biol (1987) 1.43
Oct4 kinetics predict cell lineage patterning in the early mammalian embryo. Nat Cell Biol (2011) 1.40
Experimental analysis of second cleavage in the mouse. Hum Reprod (2002) 1.25
Is the similarity of monozygotic twins due to genetic factors alone? Nature (1981) 1.25
Kinematics of gray crescent formation in Xenopus eggs: the displacement of subcortical cytoplasm relative to the egg surface. Dev Biol (1986) 1.24
Mitotic spindles and cleavage planes are oriented randomly in the two-cell mouse embryo. Curr Biol (2005) 1.20
Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction. Dev Biol (2005) 1.20
Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin. Development (2010) 1.18
Potential of isolated mouse inner cell masses to form trophectoderm derivatives in vivo. Dev Biol (1979) 1.16
Ezrin becomes restricted to outer cells following asymmetrical division in the preimplantation mouse embryo. Dev Biol (1996) 1.15
Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod (1997) 1.15
Establishment of trophectoderm and inner cell mass lineages in the mouse embryo. Mol Reprod Dev (2009) 1.12
Monozygotic twinning in rhesus monkeys by manipulation of in vitro-derived embryos. Biol Reprod (2002) 1.10
From mouse egg to mouse embryo: polarities, axes, and tissues. Annu Rev Cell Dev Biol (2009) 1.07
Distribution of antibody- and lectin-binding sites on dissociated blastomeres from mouse morulae: evidence for polarization at compaction. J Embryol Exp Morphol (1980) 1.06
Ability of outside cells from preimplantation mouse embryos to form inner cell mass derivatives. Dev Biol (1980) 1.06
Formation and consequences of cell patterns in preimplantation mouse development. J Embryol Exp Morphol (1979) 1.02
Computer simulation of emerging asymmetry in the mouse blastocyst. Development (2008) 1.02
Developmental fate and lineage commitment of singled mouse blastomeres. Development (2012) 0.94
Systems biology beyond networks: generating order from disorder through self-organization. Semin Cancer Biol (2011) 0.93
Where do we stand now? Mouse early embryo patterning meeting in Freiburg, Germany (2005). Int J Dev Biol (2006) 0.92
Generation and live imaging of an endogenous Cdx2 reporter mouse line. Genesis (2012) 0.90
Orientation of mitotic spindles during the 8- to 16-cell stage transition in mouse embryos. PLoS One (2009) 0.86
Stochastic processes during mouse blastocyst patterning. Cells Tissues Organs (2008) 0.83
Stochastic processes in the development of pluripotency in vivo. Biotechnol J (2012) 0.81
Simulating the mammalian blastocyst--molecular and mechanical interactions pattern the embryo. PLoS Comput Biol (2011) 0.81
Theoretical exploration of blastocyst morphogenesis. Int J Dev Biol (2009) 0.78
Segregation during cleavage in the mammalian embryo? A critical comparison of whole-mount/CLSM and section immunohistochemistry casts doubts on segregation of axis-relevant leptin domains in the rabbit. Histochem Cell Biol (2011) 0.76
Stochastic patterning in the mouse pre-implantation embryo. Development (2007) 3.83
Mechanism of phototaxis in marine zooplankton. Nature (2008) 2.46
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. J Cell Biol (2005) 2.21
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development. J Cell Biol (2012) 2.18
Polarity of the mouse embryo is established at blastocyst and is not prepatterned. Genes Dev (2005) 2.05
Space asymmetry directs preferential sperm entry in the absence of polarity in the mouse oocyte. PLoS Biol (2006) 1.57
A computational model predicts Xenopus meiotic spindle organization. J Cell Biol (2010) 1.53
Modelling microtubule patterns. Nat Cell Biol (2006) 1.25
Force- and length-dependent catastrophe activities explain interphase microtubule organization in fission yeast. Mol Syst Biol (2009) 1.18
Chromatin shapes the mitotic spindle. Cell (2009) 1.17
A theory of microtubule catastrophes and their regulation. Proc Natl Acad Sci U S A (2009) 1.11
Computer simulation of emerging asymmetry in the mouse blastocyst. Development (2008) 1.02
Hypomethylation of paternal DNA in the late mouse zygote is not essential for development. Int J Dev Biol (2008) 0.97
Spindle pole body-anchored Kar3 drives the nucleus along microtubules from another nucleus in preparation for nuclear fusion during yeast karyogamy. Genes Dev (2013) 0.96
Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development. Genes Dev (2012) 0.87
The mitotic spindle and actin tails. Biol Cell (2004) 0.87
Role of transglutaminase 1 in stabilisation of intercellular junctions of the vascular endothelium. Histochem Cell Biol (2004) 0.87
Dynamic rearrangement of surface proteins is essential for cytokinesis. Genesis (2008) 0.85
Patterns of molecular motors that guide and sort filaments. Lab Chip (2012) 0.83
Stochastic processes during mouse blastocyst patterning. Cells Tissues Organs (2008) 0.83
Stochastic processes in the development of pluripotency in vivo. Biotechnol J (2012) 0.81
The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo. J Biol Chem (2012) 0.80
Gradual meiosis-to-mitosis transition in the early mouse embryo. Results Probl Cell Differ (2012) 0.76
Corrigendum: Pulsatile cell-autonomous contractility drives compaction in the mouse embryo. Nat Cell Biol (2017) 0.75
[Mitotic spindle assembly depends on chromatin geometry]. Med Sci (Paris) (2010) 0.75