Published in Development on November 28, 2012
The Fibroblast Growth Factor signaling pathway. Wiley Interdiscip Rev Dev Biol (2015) 1.82
Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages. Nat Cell Biol (2013) 1.81
Oct4 cell-autonomously promotes primitive endoderm development in the mouse blastocyst. Dev Cell (2013) 1.74
Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling. PLoS One (2014) 1.44
Anatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo. Genesis (2013) 1.21
A self-organization framework for symmetry breaking in the mammalian embryo. Nat Rev Mol Cell Biol (2013) 1.20
A rapid and efficient 2D/3D nuclear segmentation method for analysis of early mouse embryo and stem cell image data. Stem Cell Reports (2014) 1.18
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell (2014) 1.12
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development (2014) 1.05
Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo. Philos Trans R Soc Lond B Biol Sci (2014) 1.04
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet (2014) 1.00
The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos. Open Biol (2013) 0.98
Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst. Cell Rep (2015) 0.96
Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells. Genes Dev (2015) 0.95
Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells. Nat Protoc (2013) 0.94
Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation. Genes Dev (2013) 0.92
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst. Stem Cells (2013) 0.90
Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells. Sci Rep (2014) 0.89
The birth of embryonic pluripotency. Philos Trans R Soc Lond B Biol Sci (2014) 0.88
Atypical protein kinase C couples cell sorting with primitive endoderm maturation in the mouse blastocyst. Development (2013) 0.88
CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development. Dev Biol (2013) 0.87
The molecular underpinnings of totipotency. Philos Trans R Soc Lond B Biol Sci (2014) 0.86
Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst. Nat Commun (2016) 0.85
OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells. Stem Cell Reports (2016) 0.84
Single cells get together: High-resolution approaches to study the dynamics of early mouse development. Semin Cell Dev Biol (2015) 0.84
FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells. Development (2015) 0.83
Cell signaling and transcription factors regulating cell fate during formation of the mouse blastocyst. Trends Genet (2015) 0.82
Primitive endoderm differentiation: from specification to epithelium formation. Philos Trans R Soc Lond B Biol Sci (2014) 0.81
From blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesis. Philos Trans R Soc Lond B Biol Sci (2014) 0.81
Developmental lineage priming in Dictyostelium by heterogeneous Ras activation. Elife (2013) 0.81
Fgfr1 regulates development through the combinatorial use of signaling proteins. Genes Dev (2015) 0.79
Destabilization of pluripotency in the absence of Mad2l2. Cell Cycle (2015) 0.79
Genetic insights into the mechanisms of Fgf signaling. Genes Dev (2016) 0.79
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development. Cell Stem Cell (2017) 0.79
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci Rep (2016) 0.77
Cell Fate Specification Based on Tristability in the Inner Cell Mass of Mouse Blastocysts. Biophys J (2016) 0.77
Clonal analyses in the anterior pre-placodal region: implications for the early lineage bias of placodal progenitors. Int J Dev Biol (2013) 0.76
Quantitative Analysis of Protein Expression to Study Lineage Specification in Mouse Preimplantation Embryos. J Vis Exp (2016) 0.76
Have you seen? Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. EMBO J (2014) 0.75
The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo. Development (2017) 0.75
p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development. Open Biol (2016) 0.75
Four simple rules that are sufficient to generate the mammalian blastocyst. PLoS Biol (2017) 0.75
ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation. Sci Rep (2017) 0.75
A multiscale model of early cell lineage specification including cell division. NPJ Syst Biol Appl (2017) 0.75
Single-cell gene expression of the bovine blastocyst. Reproduction (2017) 0.75
The ground state of embryonic stem cell self-renewal. Nature (2008) 19.44
Promotion of trophoblast stem cell proliferation by FGF4. Science (1998) 8.02
Naive and primed pluripotent states. Cell Stem Cell (2009) 7.15
Capture of authentic embryonic stem cells from rat blastocysts. Cell (2008) 6.60
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell (2010) 6.24
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development (2007) 5.62
Germline competent embryonic stem cells derived from rat blastocysts. Cell (2008) 5.52
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell (2006) 4.77
Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line. Curr Biol (1997) 4.46
An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis. Nucleic Acids Res (2006) 4.26
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development (2009) 4.25
Defined conditions for neural commitment and differentiation. Methods Enzymol (2003) 3.99
Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell (2009) 3.92
Stochastic patterning in the mouse pre-implantation embryo. Development (2007) 3.83
Requirement of FGF-4 for postimplantation mouse development. Science (1995) 3.64
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc Natl Acad Sci U S A (1998) 3.27
Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev (2002) 3.12
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell (2008) 3.08
A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. Development (2007) 2.92
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (2005) 2.91
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development (2008) 2.88
Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol (2003) 2.85
Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. Cell (1998) 2.64
FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development (2010) 2.60
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development. Nat Genet (2000) 2.59
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev (2010) 2.50
Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development (1992) 2.45
The role of FGF/Erk signaling in pluripotent cells. Development (2010) 2.40
Investigation of the fate of 4-5 day post-coitum mouse inner cell mass cells by blastocyst injection. J Embryol Exp Morphol (1979) 2.38
BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo. Development (1999) 2.16
Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo. Proc Natl Acad Sci U S A (2010) 2.12
Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body. J Cell Biol (2001) 1.58
Investigation of cell lineage and differentiation in the extraembryonic endoderm of the mouse embryo. J Embryol Exp Morphol (1982) 1.57
Lineage allocation and asymmetries in the early mouse embryo. Philos Trans R Soc Lond B Biol Sci (2003) 1.52
Expression and function of FGF-4 in peri-implantation development in mouse embryos. Development (1994) 1.51
Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling. Dev Cell (2011) 1.50
Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst. Dev Biol (2009) 1.48
Human hypoblast formation is not dependent on FGF signalling. Dev Biol (2011) 1.46
Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells. BMC Dev Biol (2007) 1.45
The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17. Dev Biol (2010) 1.34
Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo. Development (2011) 1.33
Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm. Genesis (2003) 1.31
Genetic identification of tissue of origin of cellular populations within the mouse placenta. J Embryol Exp Morphol (1985) 1.30
The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos. Development (2012) 1.23
Characterization of a binding protein for leukemia inhibitory factor localized in extracellular matrix. J Cell Biol (1993) 1.20
A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst. Development (2010) 1.18
Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates. Development (2004) 1.08
Effect of culture conditions on diploid to giant-cell transformation in postimplantation mouse trophoblast. J Embryol Exp Morphol (1981) 1.00
Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol (2012) 0.97
Afp::mCherry, a red fluorescent transgenic reporter of the mouse visceral endoderm. Genesis (2011) 0.93
An in situ cell marker for clonal analysis of development of the extraembryonic endoderm in the mouse. J Embryol Exp Morphol (1984) 0.92
Troika of the mouse blastocyst: lineage segregation and stem cells. Curr Stem Cell Res Ther (2012) 0.90
Ectopic expression of GATA6 bypasses requirement for Grb2 in primitive endoderm formation. Dev Dyn (2010) 0.85
Ex utero culture and live imaging of mouse embryos. Methods Mol Biol (2011) 0.81
[Early embryogenesis in mammals: stem cells and first commitment steps]. Med Sci (Paris) (2008) 0.78
The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Dev Cell (2005) 3.96
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell (2008) 3.08
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst. Development (2008) 2.88
Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Neuron (2008) 2.86
The first cleavage of the mouse zygote predicts the blastocyst axis. Nature (2005) 2.25
A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse. BMC Dev Biol (2010) 1.92
Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo. J Cell Sci (2005) 1.85
In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice. Genesis (2006) 1.85
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo. Blood (2011) 1.79
Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud. Dev Cell (2013) 1.79
A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3D. BMC Bioinformatics (2010) 1.69
Using a histone yellow fluorescent protein fusion for tagging and tracking endothelial cells in ES cells and mice. Genesis (2005) 1.69
Developmental potential and behavior of tetraploid cells in the mouse embryo. Dev Biol (2005) 1.56
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library. Stem Cells (2006) 1.55
Genetic and spectrally distinct in vivo imaging: embryonic stem cells and mice with widespread expression of a monomeric red fluorescent protein. BMC Biotechnol (2005) 1.52
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci U S A (2013) 1.51
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryos. BMC Dev Biol (2009) 1.40
Production of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos. Nat Protoc (2006) 1.39
The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17. Dev Biol (2010) 1.34
Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo. Development (2011) 1.33
A membrane associated mCherry fluorescent reporter line for studying vascular remodeling and cardiac function during murine embryonic development. Anat Rec (Hoboken) (2009) 1.33
Eomes::GFP-a tool for live imaging cells of the trophoblast, primitive streak, and telencephalon in the mouse embryo. Genesis (2007) 1.31
Cellular dynamics in the early mouse embryo: from axis formation to gastrulation. Curr Opin Genet Dev (2010) 1.30
Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development. Dev Dyn (2006) 1.30
Dynamic imaging of mammalian neural tube closure. Dev Biol (2010) 1.29
Transthyretin mouse transgenes direct RFP expression or Cre-mediated recombination throughout the visceral endoderm. Genesis (2009) 1.28
A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells. Development (2013) 1.26
A transgenic mouse that reveals cell shape and arrangement during ureteric bud branching. Genesis (2009) 1.26
Live-imaging fluorescent proteins in mouse embryos: multi-dimensional, multi-spectral perspectives. Trends Biotechnol (2009) 1.25
A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea. Development (2012) 1.25
Oriented cell motility and division underlie early limb bud morphogenesis. Development (2010) 1.23
Anatomy of a blastocyst: cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo. Genesis (2013) 1.21
Dual transgene strategy for live visualization of chromatin and plasma membrane dynamics in murine embryonic stem cells and embryonic tissues. Genesis (2009) 1.21
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature (2013) 1.18
A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst. Development (2010) 1.18
Nap1-mediated actin remodeling is essential for mammalian myoblast fusion. J Cell Sci (2009) 1.18
Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development (2007) 1.15
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development (2014) 1.05
Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states. Development (2012) 1.04
Imaging mouse development with confocal time-lapse microscopy. Methods Enzymol (2010) 1.03
BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity. Dev Biol (2011) 1.01
Interaction of Wnt3a, Msgn1 and Tbx6 in neural versus paraxial mesoderm lineage commitment and paraxial mesoderm differentiation in the mouse embryo. Dev Biol (2012) 1.00
Live imaging of fluorescent proteins in chordate embryos: from ascidians to mice. Microsc Res Tech (2006) 0.99
Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol (2012) 0.97
Transitions between epithelial and mesenchymal states and the morphogenesis of the early mouse embryo. Cell Adh Migr (2010) 0.95
Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells. Nat Protoc (2013) 0.94
The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev (2013) 0.94
A bright single-cell resolution live imaging reporter of Notch signaling in the mouse. BMC Dev Biol (2013) 0.94
A comparative analysis of extra-embryonic endoderm cell lines. PLoS One (2010) 0.94
BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors. J Neurosci (2012) 0.93
Afp::mCherry, a red fluorescent transgenic reporter of the mouse visceral endoderm. Genesis (2011) 0.93
Generation of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos. Methods Mol Biol (2011) 0.90
Troika of the mouse blastocyst: lineage segregation and stem cells. Curr Stem Cell Res Ther (2012) 0.90
PDGF signaling is required for primitive endoderm cell survival in the inner cell mass of the mouse blastocyst. Stem Cells (2013) 0.90
Live imaging of mouse embryos. Cold Spring Harb Protoc (2011) 0.89
eXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formation. PLoS One (2010) 0.88
Cell lineage allocation within the inner cell mass of the mouse blastocyst. Results Probl Cell Differ (2012) 0.87
Murine Notch1 is required for lymphatic vascular morphogenesis during development. Dev Dyn (2014) 0.86
Dynamic and polarized muscle cell behaviors accompany tail morphogenesis in the ascidian Ciona intestinalis. PLoS One (2007) 0.86
Photomodulatable fluorescent proteins for imaging cell dynamics and cell fate. Organogenesis (2009) 0.84
DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency. Cell Cycle (2011) 0.84
Aggregation chimeras: combining ES cells, diploid, and tetraploid embryos. Methods Mol Biol (2009) 0.83
Live imaging fluorescent proteins in early mouse embryos. Methods Enzymol (2012) 0.82
Preparation of rat serum for culturing mouse embryos. Cold Spring Harb Protoc (2011) 0.82
PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix. Elife (2013) 0.82
Microscopy to mechanism across the scales of development. Curr Opin Genet Dev (2011) 0.82
N-glycoprotein surfaceomes of four developmentally distinct mouse cell types. Proteomics Clin Appl (2014) 0.81
Ex utero culture and live imaging of mouse embryos. Methods Mol Biol (2011) 0.81
Live imaging and morphometric analysis of embryonic development in the ascidian Ciona intestinalis. Genesis (2005) 0.81
Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells. Biol Open (2012) 0.80
Sex-specific gene expression in preimplantation mouse embryos. Genome Biol (2006) 0.79
Live imaging, identifying, and tracking single cells in complex populations in vivo and ex vivo. Methods Mol Biol (2013) 0.78
Follow your gut: relaying information from the site of left-right symmetry breaking in the mouse. Genesis (2014) 0.78
Preparation of postimplantation mouse embryos for imaging. Cold Spring Harb Protoc (2011) 0.78
The multidimensionality of cell behaviors underlying morphogenesis: a case study in ascidians. Bioessays (2006) 0.77
Live imaging mouse embryonic development: seeing is believing and revealing. Methods Mol Biol (2014) 0.77
Time-lapse imaging of postimplantation mouse embryos. Cold Spring Harb Protoc (2011) 0.76
Birth defects associated with perturbations in preimplantation, gastrulation, and axis extension: from conjoined twinning to caudal dysgenesis. Wiley Interdiscip Rev Dev Biol (2012) 0.75
Mammalian development: Mechanics drives cell differentiation. Nature (2016) 0.75
A conditional mutant allele for analysis of Mixl1 function in the mouse. Genesis (2014) 0.75
Shedding light on bioscience. Symposium on Optical Imaging: Applications to Biology and Medicine. EMBO Rep (2003) 0.75
VISIONS: the art of science. Mol Reprod Dev (2009) 0.75
A cornucopia of delights for the mouse fancier. Genome Biol (2007) 0.75
Highlights of the special imaging issue. Genesis (2011) 0.75