Uwe Völker

Author PubWeight™ 207.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 2011 13.25
2 Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 2009 12.44
3 A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet 2009 6.31
4 New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 5.58
5 Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet 2009 4.97
6 Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis. Science 2012 4.41
7 Cohort profile: the study of health in Pomerania. Int J Epidemiol 2010 4.38
8 Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet 2012 3.71
9 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet 2010 3.55
10 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011 3.40
11 Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA 2013 3.15
12 New gene functions in megakaryopoiesis and platelet formation. Nature 2011 3.14
13 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
14 SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. Annu Rev Microbiol 2007 2.73
15 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA 2009 2.10
16 Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing. Mol Cell Proteomics 2009 2.08
17 Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis. Microbiology 2005 1.99
18 A genome-wide association study of metabolic traits in human urine. Nat Genet 2011 1.84
19 A comprehensive proteome map of growing Bacillus subtilis cells. Proteomics 2004 1.78
20 Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012 1.68
21 Multiple loci are associated with white blood cell phenotypes. PLoS Genet 2011 1.65
22 Genome-wide transcriptional profiling analysis of adaptation of Bacillus subtilis to high salinity. J Bacteriol 2003 1.63
23 A genome-wide association study of aging. Neurobiol Aging 2011 1.54
24 A new, accurate predictive model for incident hypertension. J Hypertens 2013 1.53
25 Genetic determinants of serum testosterone concentrations in men. PLoS Genet 2011 1.45
26 Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy. Eur Heart J 2012 1.44
27 Characterization of the human neutrophil alloantigen-3a. Nat Med 2009 1.43
28 Chill induction of the SigB-dependent general stress response in Bacillus subtilis and its contribution to low-temperature adaptation. J Bacteriol 2003 1.38
29 Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis. J Bacteriol 2005 1.35
30 High-salinity-induced iron limitation in Bacillus subtilis. J Bacteriol 2002 1.34
31 Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis. J Bacteriol 2002 1.32
32 Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS One 2012 1.31
33 Profiling of alterations in platelet proteins during storage of platelet concentrates. Transfusion 2007 1.30
34 Functional and structural characterization of RsbU, a stress signaling protein phosphatase 2C. J Biol Chem 2004 1.29
35 A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome. PLoS One 2009 1.27
36 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet 2011 1.26
37 Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP). Drug Metab Dispos 2006 1.22
38 Adaptation of Bacillus subtilis to growth at low temperature: a combined transcriptomic and proteomic appraisal. Microbiology 2006 1.21
39 Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase. Eur J Biochem 2002 1.17
40 Comparison of the proteome of Methylobacterium extorquens AM1 grown under methylotrophic and nonmethylotrophic conditions. Proteomics 2004 1.17
41 Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood. Eur J Hum Genet 2012 1.15
42 Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon. Metab Eng 2010 1.14
43 Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet 2012 1.14
44 Characterization of the human myocardial proteome in inflammatory dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies. J Proteome Res 2011 1.12
45 Human immune proteome in experimental colonization with Staphylococcus aureus. Clin Vaccine Immunol 2009 1.09
46 Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. Am J Hum Genet 2011 1.07
47 Assembly of an oxalate decarboxylase produced under sigmaK control into the Bacillus subtilis spore coat. J Bacteriol 2004 1.06
48 Assembly and function of a spore coat-associated transglutaminase of Bacillus subtilis. J Bacteriol 2005 1.05
49 Genome-wide association study of chronic periodontitis in a general German population. J Clin Periodontol 2013 1.04
50 Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation 2011 1.03
51 A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species. FEMS Microbiol Lett 2009 1.02
52 Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet 2014 1.02
53 Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet 2013 1.02
54 Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics. Proteomics 2004 1.01
55 Efficient, global-scale quantification of absolute protein amounts by integration of targeted mass spectrometry and two-dimensional gel-based proteomics. Anal Chem 2011 1.01
56 Glycerol-3-phosphate-induced catabolite repression in Escherichia coli. J Bacteriol 2002 1.01
57 Hypermetabolic syndrome as a consequence of repeated psychological stress in mice. Endocrinology 2008 1.00
58 The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy. Cancer Res 2007 1.00
59 2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM). Proteomics 2006 1.00
60 A metabolomics and proteomics study of the adaptation of Staphylococcus aureus to glucose starvation. Mol Biosyst 2011 0.99
61 Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells. J Cancer Res Clin Oncol 2007 0.99
62 Defining the structure of the general stress regulon of Bacillus subtilis using targeted microarray analysis and random forest classification. Microbiology 2011 0.98
63 Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers. Proteomics 2011 0.97
64 Cohort profile: Greifswald approach to individualized medicine (GANI_MED). J Transl Med 2014 0.97
65 Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques. Proteomics 2008 0.96
66 A novel approach to pathogen reduction in platelet concentrates using short-wave ultraviolet light. Transfusion 2009 0.95
67 A proteomics workflow for quantitative and time-resolved analysis of adaptation reactions of internalized bacteria. Methods 2013 0.94
68 The timing of cotE expression affects Bacillus subtilis spore coat morphology but not lysozyme resistance. J Bacteriol 2006 0.93
69 Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells. Cell Calcium 2008 0.92
70 Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization. J Biol Chem 2010 0.92
71 Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis. PLoS Pathog 2011 0.92
72 A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. Eur Heart J 2013 0.92
73 Immune cell activation by enterotoxin gene cluster (egc)-encoded and non-egc superantigens from Staphylococcus aureus. J Immunol 2008 0.91
74 Osmotic control of opuA expression in Bacillus subtilis and its modulation in response to intracellular glycine betaine and proline pools. J Bacteriol 2012 0.91
75 CcpA forms complexes with CodY and RpoA in Bacillus subtilis. FEBS J 2012 0.91
76 Exercise training in patients with chronic heart failure promotes restoration of high-density lipoprotein functional properties. Circ Res 2013 0.91
77 Identification of periodontitis associated changes in the proteome of whole human saliva by mass spectrometric analysis. J Clin Periodontol 2013 0.90
78 Virus-induced dilated cardiomyopathy is characterized by increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes. Proteomics 2011 0.90
79 2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics 2007 0.89
80 Proteome analysis of host-pathogen interactions: Investigation of pathogen responses to the host cell environment. Proteomics 2011 0.88
81 Profiling alterations in platelets induced by Amotosalen/UVA pathogen reduction and gamma irradiation--a LC-ESI-MS/MS-based proteomics approach. Blood Transfus 2012 0.87
82 Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates. Transfusion 2006 0.87
83 Comparative evaluation of saliva collection methods for proteome analysis. Clin Chim Acta 2013 0.87
84 Advanced tool for characterization of microbial cultures by combining cytomics and proteomics. Appl Microbiol Biotechnol 2010 0.87
85 Impaired HDL function in obese adolescents: impact of lifestyle intervention and bariatric surgery. Obesity (Silver Spring) 2013 0.86
86 Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation. PLoS One 2010 0.86
87 A description of large-scale metabolomics studies: increasing value by combining metabolomics with genome-wide SNP genotyping and transcriptional profiling. J Endocrinol 2012 0.86
88 Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches. Proteomics 2010 0.85
89 S. aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms. Cell Microbiol 2013 0.85
90 Proteomics of blood-based therapeutics: a promising tool for quality assurance in transfusion medicine. BioDrugs 2007 0.85
91 Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells. Proteomics 2010 0.85
92 Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective. Environ Microbiol 2014 0.84
93 Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells. Oncol Rep 2008 0.84
94 RsbV-independent induction of the SigB-dependent general stress regulon of Bacillus subtilis during growth at high temperature. J Bacteriol 2004 0.84
95 A network-based approach to visualize prevalence and progression of metabolic syndrome components. PLoS One 2012 0.84
96 Protein-based stable isotope probing (protein-SIP) in functional metaproteomics. Mass Spectrom Rev 2012 0.83
97 Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: analysis of changes in the myocardial proteome. Proteomics 2010 0.83
98 Proteomic identification of potential prognostic biomarkers in resectable pancreatic ductal adenocarcinoma. Proteomics 2014 0.83
99 Altered hepatic mRNA expression of immune response and apoptosis-associated genes after acute and chronic psychological stress in mice. Mol Immunol 2009 0.83
100 How mathematical modelling elucidates signalling in Bacillus subtilis. Mol Microbiol 2010 0.82
101 Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol 2013 0.82
102 Identification of Pseudomonas proteins coordinately induced by acidic amino acids and their amides: a two-dimensional electrophoresis study. Microbiology 2003 0.82
103 The alternative sigma factor B modulates virulence gene expression in a murine Staphylococcus aureus infection model but does not influence kidney gene expression pattern of the host. Int J Med Microbiol 2011 0.82
104 Transfusion medicine and proteomics. Alliance or coexistence? Blood Transfus 2010 0.81
105 Proteome analysis reveals new mechanisms of Bcl11b-loss driven apoptosis. J Proteome Res 2010 0.81
106 The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis. Lab Invest 2011 0.81
107 Translating pharmacological findings from hypothyroid rodents to euthyroid humans: is there a functional role of endogenous 3,5-T2? Thyroid 2014 0.81
108 Proteomic characterization of freeze-dried human plasma: providing treatment of bleeding disorders without the need for a cold chain. Transfusion 2008 0.81
109 Repeating structures of the major staphylococcal autolysin are essential for the interaction with human thrombospondin 1 and vitronectin. J Biol Chem 2013 0.80
110 Proteomic characterization of a pilR regulatory mutant of Azoarcus sp. strain BH72 with the aid of gel-based and gel-free approaches. Proteomics 2010 0.80
111 Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy. Am J Pathol 2011 0.80
112 A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio. J Mol Endocrinol 2012 0.80
113 Early storage lesions in apheresis platelets are induced by the activation of the integrin αIIbβ₃ and focal adhesion signaling pathways. J Proteomics 2012 0.80
114 Sulfur-36S stable isotope labeling of amino acids for quantification (SULAQ). Proteomics 2011 0.79
115 Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function. Pharmacogenet Genomics 2009 0.79
116 Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis. Eur J Clin Pharmacol 2012 0.79
117 ClpP modulates the activity of the Bacillus subtilis stress response transcription factor, sigmaB. J Bacteriol 2007 0.79
118 Functional genomics of the initial phase of cold adaptation of Pseudomonas putida KT2440. FEMS Microbiol Lett 2011 0.79
119 Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. Proteomics 2013 0.79
120 An unorthodox pancreatic lesion in a young man presenting with jaundice. Gastroenterology 2011 0.79
121 Labeling of the pathogenic bacterium Staphylococcus aureus with gold or ferric oxide-core nanoparticles highlights new capabilities for investigation of host-pathogen interactions. Cytometry A 2013 0.79
122 OMICS-based exploration of the molecular phenotype of resident cardiac progenitor cells from adult murine heart. J Proteomics 2012 0.78
123 Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model. PLoS One 2013 0.78
124 Regression of polypoid nasal mucosa after systemic corticosteroid therapy: a proteomics study. Am J Rhinol Allergy 2009 0.78
125 Comparison of genotyping using pooled DNA samples (allelotyping) and individual genotyping using the affymetrix genome-wide human SNP array 6.0. BMC Genomics 2013 0.78
126 Low dose proteasome inhibition affects alternative splicing. J Proteome Res 2012 0.78
127 Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma. Anticancer Res 2007 0.78
128 Effects of irbesartan on gene expression revealed by transcriptome analysis of left atrial tissue in a porcine model of acute rapid pacing in vivo. Int J Cardiol 2013 0.78
129 Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72. PLoS One 2012 0.78
130 Genome-wide meta-analyses of plasma renin activity and concentration reveal association with the kininogen 1 and prekallikrein genes. Circ Cardiovasc Genet 2014 0.78
131 Proteomics approaches for the analysis of enriched microbial subpopulations and visualization of complex functional information. Curr Opin Biotechnol 2012 0.77
132 A genomewide association study of smoking relapse in four European population-based samples. Psychiatr Genet 2013 0.77
133 Neuroproteomics in stem cell differentiation. Proteomics Clin Appl 2007 0.77
134 Correlates of adverse outcomes in abdominally obese individuals: findings from the five-year followup of the population-based study of health in Pomerania. J Obes 2013 0.77
135 Deletion of membrane-associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus. Mol Microbiol 2014 0.77
136 Potential role of antibodies against cardiac Kv channel-interacting protein 2 in dilated cardiomyopathy. Am Heart J 2008 0.77
137 Immunoadsorption and subsequent immunoglobulin substitution decreases myocardial gene expression of desmin in dilated cardiomyopathy. J Mol Med (Berl) 2007 0.76
138 Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis. Proteomics 2002 0.76
139 Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis. Mol Biosyst 2012 0.76
140 Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry. Pharmacogenet Genomics 2006 0.76
141 Altered immune proteome of Staphylococcus aureus under iron-restricted growth conditions. Proteomics 2014 0.76
142 Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome. J Hypertens 2011 0.76
143 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
144 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest 2017 0.75
145 Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circ Cardiovasc Genet 2016 0.75
146 A time resolved metabolomics study: the influence of different carbon sources during growth and starvation of Bacillus subtilis. Mol Biosyst 2014 0.75
147 In-depth proteomic analysis of the human cerumen-a potential novel diagnostically relevant biofluid. J Proteomics 2013 0.75
148 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet 2017 0.75
149 Characterization of the human myocardial proteome in dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies. Methods Mol Biol 2013 0.75
150 Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. Circ Cardiovasc Genet 2017 0.75
151 Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep 2017 0.75
152 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
153 Purification and biochemical characterization of a lysosomal α-fucosidase from the deuterostomia Asterias rubens. Biochimie 2012 0.75
154 2-DE proteomic profiling of neuronal stem cells. Neurodegener Dis 2006 0.75
155 Antibodies against potassium channel interacting protein 2 induce necrosis in isolated rat cardiomyocytes. J Cell Biochem 2014 0.75
156 Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells. Thromb Haemost 2016 0.75
157 Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun 2015 0.75
158 Complete primary structure of a newly characterized galactose-specific lectin from the seeds of Dolichos lablab. Glycoconj J 2008 0.75